MAPPFinder 2.0 Results for the Gene Ontology File: C:\Users\Taur.vil\Desktop\Vilgalys_2013_10_10_VibrioFileOne.gex Table: DecreasedVibrio_2009_TV-Criterion1-GO Database: C:\Users\Taur.vil\Downloads\Vc-Std_External_20090622\Vc-Std_External_20090622.gdb colors:|Pathogenic vs lab| 6/18/2009 Vibrio cholerae Pvalues = true Calculation Summary: 579 probes met the [AvgLogFC_all]<-0.25 AND [Pvalue]<0.05 criteria. 474 probes meeting the filter linked to a UniProt ID. 255 genes meeting the criterion linked to a GO term. 5221 Probes in this dataset 4449 Probes linked to a UniProt ID. 1990 Genes linked to a GO term. The z score is based on an N of 1990 and a R of 255 distinct genes in the GO. GOID GO Name GO Type Number Changed Local Number Measured Local Number in GO Local Percent Changed Local Percent Present Local Number Changed Number Measured Number in GO Percent Changed Percent Present Z Score PermuteP AdjustedP 0006457 protein folding P 12 22 23 54.54546 95.65218 12 22 24 54.54546 91.66666 5.887 0 0.001 0046417 chorismate metabolic process P 0 0 0 0 0 4 4 16 100 25 5.221 0 0.027 0009073 aromatic amino acid family biosynthetic process P 4 4 16 100 25 4 4 16 100 25 5.221 0 0.027 0005737 cytoplasm C 38 154 322 24.67533 47.82609 46 216 396 21.2963 54.54546 3.949 0 0.362 0008270 zinc ion binding F 14 46 74 30.43478 62.16216 14 46 74 30.43478 62.16216 3.617 0 0.941 0044424 intracellular part C 0 0 0 0 0 48 240 430 20 55.81395 3.551 0 0.941 0051082 unfolded protein binding F 6 10 11 60 90.90909 6 10 11 60 90.90909 4.474 0.001 0.244 0009072 aromatic amino acid family metabolic process P 0 1 4 0 25 4 6 21 66.66666 28.57143 3.952 0.001 0.362 0005351 sugar:hydrogen symporter activity F 10 28 34 35.71429 82.35294 10 28 34 35.71429 82.35294 3.65 0.001 0.941 0005402 cation:sugar symporter activity F 0 0 0 0 0 10 28 34 35.71429 82.35294 3.65 0.001 0.941 0015295 solute:hydrogen symporter activity F 0 0 0 0 0 10 28 34 35.71429 82.35294 3.65 0.001 0.941 0009401 phosphoenolpyruvate-dependent sugar phosphotransferase system P 9 24 26 37.5 92.30769 9 24 26 37.5 92.30769 3.639 0.001 0.941 0051119 sugar transmembrane transporter activity F 0 0 0 0 0 10 29 35 34.48276 82.85714 3.516 0.001 0.941 0008982 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity F 7 15 17 46.66667 88.23529 7 15 17 46.66667 88.23529 3.936 0.002 0.362 0015144 carbohydrate transmembrane transporter activity F 0 0 0 0 0 10 30 36 33.33333 83.33334 3.387 0.002 0.95 0016020 membrane C 39 449 489 8.685968 91.82004 52 560 602 9.285714 93.02325 -2.946 0.002 0.981 0040011 locomotion P 0 0 0 0 0 2 85 88 2.352941 96.59091 -2.948 0.002 0.981 0003746 translation elongation factor activity F 4 6 7 66.66666 85.71429 4 6 7 66.66666 85.71429 3.952 0.003 0.362 0006414 translational elongation P 4 6 7 66.66666 85.71429 4 6 7 66.66666 85.71429 3.952 0.003 0.362 0016859 cis-trans isomerase activity F 0 0 0 0 0 5 9 11 55.55556 81.81818 3.844 0.003 0.395 0003755 peptidyl-prolyl cis-trans isomerase activity F 5 9 10 55.55556 90 5 9 10 55.55556 90 3.844 0.003 0.395 0008643 carbohydrate transport P 5 17 23 29.41176 73.91304 10 32 38 31.25 84.21053 3.145 0.003 0.976 0009605 response to external stimulus P 0 0 0 0 0 2 75 79 2.666667 94.93671 -2.679 0.003 0.998 0043648 dicarboxylic acid metabolic process P 0 0 0 0 0 4 6 26 66.66666 23.07692 3.952 0.004 0.362 0005515 protein binding F 9 30 32 30 93.75 17 70 79 24.28572 88.6076 2.923 0.004 0.981 0051179 localization P 0 0 0 0 0 35 419 456 8.353222 91.88596 -3.074 0.004 0.978 0060089 molecular transducer activity F 0 0 0 0 0 10 173 177 5.780347 97.74011 -2.896 0.005 0.981 0004871 signal transducer activity F 5 106 110 4.716981 96.36364 10 173 177 5.780347 97.74011 -2.896 0.005 0.981 0015293 symporter activity F 0 1 1 0 100 12 44 50 27.27273 88 2.901 0.006 0.981 0015294 solute:cation symporter activity F 0 0 0 0 0 12 44 50 27.27273 88 2.901 0.006 0.981 0005622 intracellular C 19 180 197 10.55556 91.37056 60 352 547 17.04545 64.35101 2.617 0.006 0.999 0051234 establishment of localization P 0 0 0 0 0 34 392 429 8.67347 91.37529 -2.736 0.006 0.998 0006810 transport P 22 270 304 8.148149 88.81579 34 392 429 8.67347 91.37529 -2.736 0.006 0.998 0009166 nucleotide catabolic process P 3 4 6 75 66.66666 3 4 7 75 57.14286 3.724 0.007 0.563 0016896 exoribonuclease activity, producing 5’-phosphomonoesters F 2 2 2 100 100 3 4 6 75 66.66666 3.724 0.007 0.563 0004532 exoribonuclease activity F 0 0 0 0 0 3 4 6 75 66.66666 3.724 0.007 0.563 0046872 metal ion binding F 17 74 175 22.97297 42.28571 32 161 276 19.87578 58.33333 2.796 0.007 0.985 0016408 C-acyltransferase activity F 0 0 0 0 0 2 2 4 100 50 3.69 0.008 0.941 0016453 C-acetyltransferase activity F 0 0 0 0 0 2 2 2 100 100 3.69 0.008 0.941 0009055 electron carrier activity F 2 69 83 2.898551 83.13253 2 69 83 2.898551 83.13253 -2.507 0.008 1 0043167 ion binding F 0 0 0 0 0 34 174 290 19.54023 60 2.778 0.009 0.998 0006066 cellular alcohol metabolic process P 1 1 1 100 100 9 32 50 28.125 64 2.612 0.01 0.999 0005215 transporter activity F 11 150 161 7.333333 93.1677 27 323 353 8.359133 91.50142 -2.617 0.012 0.999 0004519 endonuclease activity F 5 10 15 50 66.66666 6 16 23 37.5 69.56522 2.965 0.013 0.981 0008312 7S RNA binding F 2 2 2 100 100 2 2 2 100 100 3.69 0.014 0.941 0048500 signal recognition particle C 2 2 2 100 100 2 2 2 100 100 3.69 0.014 0.941 0003824 catalytic activity F 50 274 403 18.24817 67.99007 150 1022 1416 14.6771 72.17514 2.554 0.014 1 0003849 3-deoxy-7-phosphoheptulonate synthase activity F 2 2 2 100 100 2 2 2 100 100 3.69 0.016 0.941 0045182 translation regulator activity F 0 0 0 0 0 5 12 13 41.66667 92.30769 2.999 0.016 0.978 0008135 translation factor activity, nucleic acid binding F 0 0 0 0 0 5 12 13 41.66667 92.30769 2.999 0.016 0.978 0019538 protein metabolic process P 0 5 9 0 55.55556 39 212 269 18.39623 78.81041 2.572 0.016 1 0042026 protein refolding P 2 2 2 100 100 2 2 2 100 100 3.69 0.017 0.941 0006006 glucose metabolic process P 2 5 6 40 83.33334 6 18 30 33.33333 60 2.616 0.017 0.999 0016788 hydrolase activity, acting on ester bonds F 2 9 11 22.22222 81.81818 17 76 104 22.36842 73.07692 2.54 0.017 1 0007076 mitotic chromosome condensation P 3 5 5 60 100 3 5 5 60 100 3.16 0.019 0.974 0007067 mitosis P 0 0 0 0 0 3 5 5 60 100 3.16 0.019 0.974 0022403 cell cycle phase P 0 0 0 0 0 3 5 5 60 100 3.16 0.019 0.974 0000070 mitotic sister chromatid segregation P 0 0 0 0 0 3 5 5 60 100 3.16 0.019 0.974 0000278 mitotic cell cycle P 0 0 0 0 0 3 5 5 60 100 3.16 0.019 0.974 0051276 chromosome organization P 0 0 0 0 0 3 5 5 60 100 3.16 0.019 0.974 0000087 M phase of mitotic cell cycle P 0 0 0 0 0 3 5 5 60 100 3.16 0.019 0.974 0000819 sister chromatid segregation P 0 0 0 0 0 3 5 5 60 100 3.16 0.019 0.974 0006323 DNA packaging P 0 0 0 0 0 3 5 5 60 100 3.16 0.019 0.974 0030261 chromosome condensation P 1 2 2 50 100 3 5 5 60 100 3.16 0.019 0.974 0022402 cell cycle process P 0 0 0 0 0 3 5 5 60 100 3.16 0.019 0.974 0000279 M phase P 0 0 0 0 0 3 5 5 60 100 3.16 0.019 0.974 0008152 metabolic process P 42 237 339 17.72152 69.91151 158 1098 1471 14.3898 74.6431 2.333 0.019 1 0000155 two-component sensor activity F 1 48 50 2.083333 96 1 48 50 2.083333 96 -2.251 0.019 1 0004672 protein kinase activity F 0 0 0 0 0 1 48 50 2.083333 96 -2.251 0.019 1 0004673 protein histidine kinase activity F 1 40 42 2.5 95.2381 1 48 50 2.083333 96 -2.251 0.019 1 0008746 NAD(P) transhydrogenase activity F 1 1 1 100 100 2 2 3 100 66.66666 3.69 0.02 0.941 0008750 NAD(P)+ transhydrogenase (AB-specific) activity F 2 2 2 100 100 2 2 2 100 100 3.69 0.02 0.941 0016652 oxidoreductase activity, acting on NADH or NADPH, NAD or NADP as acceptor F 0 0 0 0 0 2 2 3 100 66.66666 3.69 0.02 0.941 0019842 vitamin binding F 0 0 0 0 0 10 38 56 26.31579 67.85714 2.514 0.02 1 0004518 nuclease activity F 3 15 24 20 62.5 10 39 52 25.64103 75 2.42 0.02 1 0007610 behavior P 0 0 0 0 0 2 66 69 3.030303 95.65218 -2.418 0.02 1 0007626 locomotory behavior P 0 0 0 0 0 2 66 69 3.030303 95.65218 -2.418 0.02 1 0042330 taxis P 0 0 0 0 0 2 66 69 3.030303 95.65218 -2.418 0.02 1 0006935 chemotaxis P 2 65 68 3.076923 95.58823 2 66 69 3.030303 95.65218 -2.418 0.02 1 0006007 glucose catabolic process P 0 0 1 0 0 4 9 19 44.44444 47.36842 2.845 0.021 0.985 0019320 hexose catabolic process P 0 0 0 0 0 4 9 19 44.44444 47.36842 2.845 0.021 0.985 0008565 protein transporter activity F 1 45 45 2.222222 100 1 50 50 2 100 -2.316 0.021 1 0016775 phosphotransferase activity, nitrogenous group as acceptor F 0 0 0 0 0 1 50 52 2 96.15385 -2.316 0.022 1 0009095 aromatic amino acid family biosynthetic process, prephenate pathway P 0 0 0 0 0 2 2 2 100 100 3.69 0.023 0.941 0004106 chorismate mutase activity F 2 2 2 100 100 2 2 2 100 100 3.69 0.023 0.941 0044267 cellular protein metabolic process P 2 2 2 100 100 38 207 263 18.35749 78.70722 2.52 0.023 1 0006996 organelle organization P 0 0 0 0 0 8 28 29 28.57143 96.55173 2.512 0.023 1 0009279 cell outer membrane C 9 34 36 26.47059 94.44444 9 34 36 26.47059 94.44444 2.402 0.024 1 0016853 isomerase activity F 10 41 66 24.39024 62.12121 12 50 77 24 64.93507 2.396 0.025 1 0044238 primary metabolic process P 0 2 2 0 100 117 788 1083 14.84772 72.76085 2.197 0.025 1 0003989 acetyl-CoA carboxylase activity F 2 2 3 100 66.66666 2 2 3 100 66.66666 3.69 0.026 0.941 0016421 CoA carboxylase activity F 0 0 0 0 0 2 2 3 100 66.66666 3.69 0.026 0.941 0009317 acetyl-CoA carboxylase complex C 2 2 3 100 66.66666 2 2 3 100 66.66666 3.69 0.026 0.941 0016885 ligase activity, forming carbon-carbon bonds F 0 0 0 0 0 2 2 3 100 66.66666 3.69 0.026 0.941 0004540 ribonuclease activity F 1 6 7 16.66667 85.71429 4 9 15 44.44444 60 2.845 0.026 0.985 0019843 rRNA binding F 0 33 34 0 97.05882 0 33 34 0 97.05882 -2.22 0.026 1 0006605 protein targeting P 1 3 3 33.33333 100 3 6 6 50 100 2.729 0.027 0.998 0015291 secondary active transmembrane transporter activity F 0 0 0 0 0 15 69 77 21.73913 89.61039 2.257 0.027 1 0042995 cell projection C 0 0 0 0 0 1 48 50 2.083333 96 -2.251 0.028 1 0046365 monosaccharide catabolic process P 0 0 0 0 0 4 10 20 40 50 2.578 0.029 1 0006304 DNA modification P 1 2 2 50 100 3 6 8 50 75 2.729 0.03 0.998 0003924 GTPase activity F 4 10 12 40 83.33334 4 10 12 40 83.33334 2.578 0.032 1 0019438 aromatic compound biosynthetic process P 0 0 0 0 0 5 15 33 33.33333 45.45454 2.386 0.032 1 0031323 regulation of cellular metabolic process P 0 0 0 0 0 22 250 261 8.8 95.78544 -2.03 0.033 1 0045449 regulation of transcription P 2 35 37 5.714286 94.5946 21 243 254 8.641975 95.66929 -2.076 0.033 1 0019318 hexose metabolic process P 0 1 1 0 100 6 21 35 28.57143 60 2.171 0.034 1 0051252 regulation of RNA metabolic process P 0 2 2 0 100 21 242 251 8.677686 96.41434 -2.054 0.034 1 0006350 transcription P 12 130 137 9.230769 94.89051 21 244 259 8.606558 94.2085 -2.099 0.034 1 0006096 glycolysis P 3 6 14 50 42.85714 3 6 14 50 42.85714 2.729 0.035 0.998 0005488 binding F 13 86 116 15.11628 74.13793 137 946 1214 14.48203 77.92422 2.119 0.035 1 0032502 developmental process P 0 0 0 0 0 0 28 44 0 63.63636 -2.043 0.035 1 0032940 secretion by cell P 0 0 0 0 0 1 43 43 2.325581 100 -2.08 0.035 1 0009306 protein secretion P 0 29 29 0 100 1 43 43 2.325581 100 -2.08 0.035 1 0046903 secretion P 0 0 0 0 0 1 43 43 2.325581 100 -2.08 0.035 1 0019867 outer membrane C 5 16 16 31.25 100 10 40 42 25 95.2381 2.329 0.036 1 0006886 intracellular protein transport P 2 7 7 28.57143 100 5 16 16 31.25 100 2.215 0.036 1 0046907 intracellular transport P 0 0 0 0 0 5 16 16 31.25 100 2.215 0.036 1 0030528 transcription regulator activity F 0 9 9 0 100 18 211 217 8.530806 97.23502 -1.968 0.036 1 0019104 DNA N-glycosylase activity F 1 1 1 100 100 2 3 4 66.66666 75 2.792 0.039 0.998 0006613 cotranslational protein targeting to membrane P 0 0 0 0 0 2 3 3 66.66666 100 2.792 0.04 0.998 0006614 SRP-dependent cotranslational protein targeting to membrane P 2 3 3 66.66666 100 2 3 3 66.66666 100 2.792 0.04 0.998 0045047 protein targeting to ER P 0 0 0 0 0 2 3 3 66.66666 100 2.792 0.04 0.998 0006612 protein targeting to membrane P 0 0 0 0 0 2 3 3 66.66666 100 2.792 0.04 0.998 0017171 serine hydrolase activity F 0 0 0 0 0 6 21 24 28.57143 87.5 2.171 0.04 1 0008236 serine-type peptidase activity F 1 5 6 20 83.33334 6 21 24 28.57143 87.5 2.171 0.04 1 0006355 regulation of transcription, DNA-dependent P 21 239 248 8.786611 96.37096 21 240 249 8.75 96.38554 -2.008 0.04 1 0006351 transcription, DNA-dependent P 0 0 4 0 0 21 241 254 8.713693 94.88189 -2.031 0.04 1 0032774 RNA biosynthetic process P 0 0 0 0 0 21 241 255 8.713693 94.5098 -2.031 0.04 1 0031224 intrinsic to membrane C 0 0 0 0 0 32 340 358 9.411765 94.97207 -2.061 0.042 1 0046164 alcohol catabolic process P 0 0 0 0 0 4 11 22 36.36364 50 2.343 0.043 1 0044425 membrane part C 0 0 0 0 0 33 349 377 9.455587 92.57294 -2.067 0.043 1 0016758 transferase activity, transferring hexosyl groups F 0 1 2 0 50 2 3 8 66.66666 37.5 2.792 0.044 0.998 0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process P 0 0 0 0 0 22 248 259 8.870968 95.7529 -1.985 0.044 1 0019222 regulation of metabolic process P 0 0 0 0 0 23 257 270 8.949416 95.18519 -1.986 0.044 1 0016829 lyase activity F 4 20 73 20 27.39726 12 55 108 21.81818 50.92593 2.026 0.046 1 0019861 flagellum C 1 30 32 3.333333 93.75 1 44 46 2.272727 95.65218 -2.115 0.046 1 0016021 integral to membrane C 32 335 353 9.552238 94.90085 32 339 357 9.439528 94.95798 -2.04 0.048 1 0048856 anatomical structure development P 0 0 0 0 0 0 24 40 0 60 -1.889 0.049 1 0009653 anatomical structure morphogenesis P 0 0 0 0 0 0 24 40 0 60 -1.889 0.049 1 0032989 cellular structure morphogenesis P 0 0 0 0 0 0 24 40 0 60 -1.889 0.049 1 0000902 cell morphogenesis P 0 1 2 0 50 0 24 40 0 60 -1.889 0.049 1 0048869 cellular developmental process P 0 0 0 0 0 0 24 40 0 60 -1.889 0.049 1 0010556 regulation of macromolecule biosynthetic process P 0 0 0 0 0 22 247 258 8.906882 95.73643 -1.963 0.05 1 0031326 regulation of cellular biosynthetic process P 0 0 0 0 0 22 247 258 8.906882 95.73643 -1.963 0.05 1 0009889 regulation of biosynthetic process P 0 0 0 0 0 22 247 258 8.906882 95.73643 -1.963 0.05 1 0034613 cellular protein localization P 0 0 0 0 0 5 17 17 29.41176 100 2.056 0.052 1 0016310 phosphorylation P 1 37 45 2.702703 82.22222 2 53 66 3.773585 80.30303 -1.995 0.052 1 0010468 regulation of gene expression P 0 0 0 0 0 22 248 261 8.870968 95.01916 -1.985 0.053 1 0070011 peptidase activity, acting on L-amino acid peptides F 0 1 1 0 100 13 61 70 21.31148 87.14286 2.016 0.054 1 0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor F 1 2 2 50 100 2 3 5 66.66666 60 2.792 0.055 0.998 0019725 cellular homeostasis P 0 0 0 0 0 6 23 27 26.08696 85.18519 1.915 0.06 1 0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5’-phosphomonoesters F 0 0 0 0 0 3 8 12 37.5 66.66666 2.093 0.061 1 0004252 serine-type endopeptidase activity F 4 13 16 30.76923 81.25 4 13 16 30.76923 81.25 1.943 0.063 1 0008081 phosphoric diester hydrolase activity F 1 2 2 50 100 2 4 5 50 80 2.227 0.064 1 0006284 base-excision repair P 2 4 5 50 80 2 4 5 50 80 2.227 0.065 1 0008610 lipid biosynthetic process P 2 8 18 25 44.44444 8 33 60 24.24242 55 1.98 0.065 1 0016835 carbon-oxygen lyase activity F 0 2 2 0 100 5 18 40 27.77778 45 1.908 0.065 1 0060255 regulation of macromolecule metabolic process P 0 0 0 0 0 23 253 266 9.090909 95.11279 -1.896 0.066 1 0018106 peptidyl-histidine phosphorylation P 1 39 41 2.564103 95.12195 1 39 41 2.564103 95.12195 -1.934 0.067 1 0006468 protein amino acid phosphorylation P 0 0 0 0 0 1 39 41 2.564103 95.12195 -1.934 0.067 1 0018202 peptidyl-histidine modification P 0 0 0 0 0 1 39 41 2.564103 95.12195 -1.934 0.067 1 0003700 transcription factor activity F 12 151 152 7.94702 99.3421 12 151 152 7.94702 99.3421 -1.861 0.068 1 0043169 cation binding F 2 12 13 16.66667 92.30769 25 137 213 18.24817 64.31925 1.972 0.069 1 0045454 cell redox homeostasis P 5 18 22 27.77778 81.81818 5 18 22 27.77778 81.81818 1.908 0.069 1 0009987 cellular process P 1 3 3 33.33333 100 154 1101 1453 13.98728 75.77426 1.742 0.072 1 0004176 ATP-dependent peptidase activity F 2 4 4 50 100 2 4 4 50 100 2.227 0.073 1 0046677 response to antibiotic P 2 4 6 50 66.66666 2 4 6 50 66.66666 2.227 0.077 1 0030170 pyridoxal phosphate binding F 7 28 44 25 63.63636 7 28 44 25 63.63636 1.942 0.077 1 0015932 nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity F 0 0 0 0 0 2 4 4 50 100 2.227 0.078 1 0005337 nucleoside transmembrane transporter activity F 1 1 1 100 100 2 4 4 50 100 2.227 0.078 1 0016799 hydrolase activity, hydrolyzing N-glycosyl compounds F 0 0 1 0 0 2 4 5 50 80 2.227 0.078 1 0016757 transferase activity, transferring glycosyl groups F 0 5 23 0 21.73913 4 13 31 30.76923 41.93548 1.943 0.079 1 0006508 proteolysis P 13 61 69 21.31148 88.4058 13 63 72 20.63492 87.5 1.887 0.079 1 0016070 RNA metabolic process P 0 2 3 0 66.66666 29 298 354 9.731544 84.18079 -1.726 0.079 1 0042221 response to chemical stimulus P 0 0 0 0 0 5 81 89 6.17284 91.01124 -1.825 0.079 1 0006730 one-carbon compound metabolic process P 1 1 7 100 14.28571 4 13 21 30.76923 61.90476 1.943 0.081 1 0019344 cysteine biosynthetic process P 1 1 4 100 25 2 4 7 50 57.14286 2.227 0.083 1 0006534 cysteine metabolic process P 0 0 2 0 0 2 4 9 50 44.44444 2.227 0.083 1 0042592 homeostatic process P 0 0 0 0 0 7 29 34 24.13793 85.29412 1.837 0.083 1 0016836 hydro-lyase activity F 0 2 6 0 33.33333 3 9 27 33.33333 33.33333 1.845 0.091 1 0000160 two-component signal transduction system (phosphorelay) P 7 100 104 7 96.15385 7 100 104 7 96.15385 -1.784 0.091 1 0007059 chromosome segregation P 2 7 7 28.57143 100 3 9 9 33.33333 100 1.845 0.093 1 0005996 monosaccharide metabolic process P 0 0 0 0 0 6 24 38 25 63.15789 1.796 0.094 1 0006793 phosphorus metabolic process P 0 0 0 0 0 3 56 73 5.357143 76.71233 -1.693 0.1 1 0006796 phosphate metabolic process P 0 0 1 0 0 3 56 72 5.357143 77.77778 -1.693 0.1 1 0005198 structural molecule activity F 0 13 14 0 92.85714 3 61 69 4.918033 88.4058 -1.874 0.1 1 0016833 oxo-acid-lyase activity F 0 1 2 0 50 2 5 10 40 50 1.821 0.101 1 0046914 transition metal ion binding F 0 4 4 0 100 19 105 173 18.09524 60.69364 1.663 0.101 1 0009165 nucleotide biosynthetic process P 0 1 5 0 20 0 21 55 0 38.18182 -1.766 0.111 1 0004067 asparaginase activity F 1 1 1 100 100 1 1 1 100 100 2.608 0.112 1 0008663 2’,3’-cyclic-nucleotide 2’-phosphodiesterase activity F 1 1 1 100 100 1 1 1 100 100 2.608 0.112 1 0004112 cyclic-nucleotide phosphodiesterase activity F 0 0 1 0 0 1 1 2 100 50 2.608 0.112 1 0043165 cell outer membrane assembly P 1 1 1 100 100 1 1 1 100 100 2.608 0.113 1 0043163 cell envelope organization P 0 0 0 0 0 1 1 1 100 100 2.608 0.113 1 0007049 cell cycle P 5 22 31 22.72727 70.96774 6 24 33 25 72.72727 1.796 0.114 1 0043022 ribosome binding F 1 1 1 100 100 1 1 1 100 100 2.608 0.115 1 0042274 ribosomal small subunit biogenesis P 1 1 1 100 100 1 1 1 100 100 2.608 0.115 1 0043021 ribonucleoprotein binding F 0 0 0 0 0 1 1 1 100 100 2.608 0.115 1 0016887 ATPase activity F 2 59 71 3.389831 83.09859 7 97 115 7.216495 84.34782 -1.691 0.115 1 0031388 organic acid phosphorylation P 1 1 1 100 100 1 1 1 100 100 2.608 0.116 1 0008887 glycerate kinase activity F 1 1 1 100 100 1 1 1 100 100 2.608 0.116 1 0008861 formate C-acetyltransferase activity F 1 1 1 100 100 1 1 1 100 100 2.608 0.116 1 0009244 lipopolysaccharide core region biosynthetic process P 2 5 5 40 100 2 5 5 40 100 1.821 0.116 1 0009311 oligosaccharide metabolic process P 0 0 0 0 0 2 5 5 40 100 1.821 0.116 1 0046401 lipopolysaccharide core region metabolic process P 0 0 0 0 0 2 5 5 40 100 1.821 0.116 1 0009312 oligosaccharide biosynthetic process P 0 0 0 0 0 2 5 5 40 100 1.821 0.116 1 0001510 RNA methylation P 0 0 0 0 0 1 1 1 100 100 2.608 0.117 1 0008650 rRNA (uridine-2’-O-)-methyltransferase activity F 1 1 1 100 100 1 1 1 100 100 2.608 0.117 1 0008171 O-methyltransferase activity F 0 0 0 0 0 1 1 6 100 16.66667 2.608 0.117 1 0031167 rRNA methylation P 1 1 1 100 100 1 1 1 100 100 2.608 0.117 1 0008935 naphthoate synthase activity F 1 1 1 100 100 1 1 1 100 100 2.608 0.118 1 0044237 cellular metabolic process P 0 5 9 0 55.55556 123 873 1211 14.08935 72.08918 1.504 0.118 1 0004844 uracil DNA N-glycosylase activity F 1 1 1 100 100 1 1 1 100 100 2.608 0.119 1 0031365 N-terminal protein amino acid modification P 0 0 0 0 0 1 1 1 100 100 2.608 0.119 1 0006473 protein amino acid acetylation P 0 0 0 0 0 1 1 1 100 100 2.608 0.119 1 0018409 peptide or protein amino-terminal blocking P 0 0 0 0 0 1 1 1 100 100 2.608 0.119 1 0006474 N-terminal protein amino acid acetylation P 1 1 1 100 100 1 1 1 100 100 2.608 0.119 1 0015307 drug:hydrogen antiporter activity F 0 0 0 0 0 1 1 1 100 100 2.608 0.119 1 0042895 antibiotic transporter activity F 0 0 0 0 0 1 1 1 100 100 2.608 0.119 1 0008493 tetracycline transporter activity F 0 0 0 0 0 1 1 1 100 100 2.608 0.119 1 0015904 tetracycline transport P 1 1 1 100 100 1 1 1 100 100 2.608 0.119 1 0015520 tetracycline:hydrogen antiporter activity F 1 1 1 100 100 1 1 1 100 100 2.608 0.119 1 0043543 protein amino acid acylation P 0 0 0 0 0 1 1 1 100 100 2.608 0.119 1 0043093 binary fission P 1 1 1 100 100 1 1 1 100 100 2.608 0.121 1 0032505 reproduction of a single-celled organism P 0 0 0 0 0 1 1 1 100 100 2.608 0.121 1 0000003 reproduction P 0 0 0 0 0 1 1 1 100 100 2.608 0.121 1 0019954 asexual reproduction P 0 0 0 0 0 1 1 1 100 100 2.608 0.121 1 0004177 aminopeptidase activity F 2 5 8 40 62.5 2 5 8 40 62.5 1.821 0.121 1 0003711 transcription elongation regulator activity F 2 5 5 40 100 2 5 5 40 100 1.821 0.122 1 0004850 uridine phosphorylase activity F 1 1 1 100 100 1 1 1 100 100 2.608 0.123 1 0008890 glycine C-acetyltransferase activity F 1 1 1 100 100 1 1 1 100 100 2.608 0.123 1 0006857 oligopeptide transport P 1 1 1 100 100 1 1 1 100 100 2.608 0.123 1 0008977 prephenate dehydrogenase activity F 1 1 1 100 100 1 1 1 100 100 2.608 0.124 1 0004665 prephenate dehydrogenase (NADP+) activity F 1 1 1 100 100 1 1 1 100 100 2.608 0.124 1 0006571 tyrosine biosynthetic process P 1 1 1 100 100 1 1 1 100 100 2.608 0.124 1 0006531 aspartate metabolic process P 1 1 1 100 100 1 1 1 100 100 2.608 0.126 1 0008797 aspartate ammonia-lyase activity F 1 1 1 100 100 1 1 1 100 100 2.608 0.126 1 0030523 dihydrolipoamide S-acyltransferase activity F 0 0 0 0 0 1 1 1 100 100 2.608 0.127 1 0006955 immune response P 1 1 1 100 100 1 1 1 100 100 2.608 0.127 1 0016418 S-acetyltransferase activity F 0 0 0 0 0 1 1 1 100 100 2.608 0.127 1 0005149 interleukin-1 receptor binding F 1 1 1 100 100 1 1 1 100 100 2.608 0.127 1 0045254 pyruvate dehydrogenase complex C 1 1 1 100 100 1 1 1 100 100 2.608 0.127 1 0004742 dihydrolipoyllysine-residue acetyltransferase activity F 1 1 1 100 100 1 1 1 100 100 2.608 0.127 1 0002376 immune system process P 0 0 0 0 0 1 1 1 100 100 2.608 0.127 1 0005102 receptor binding F 0 0 0 0 0 1 1 1 100 100 2.608 0.127 1 0008083 growth factor activity F 0 0 0 0 0 1 1 1 100 100 2.608 0.127 1 0009057 macromolecule catabolic process P 0 0 0 0 0 6 24 42 25 57.14286 1.796 0.127 1 0006629 lipid metabolic process P 2 12 16 16.66667 75 10 50 83 20 60.24096 1.539 0.128 1 0016053 organic acid biosynthetic process P 0 0 0 0 0 3 10 23 30 43.47826 1.63 0.129 1 0046394 carboxylic acid biosynthetic process P 0 0 0 0 0 3 10 23 30 43.47826 1.63 0.129 1 0006633 fatty acid biosynthetic process P 3 8 15 37.5 53.33333 3 10 17 30 58.82353 1.63 0.129 1 0018193 peptidyl-amino acid modification P 0 0 0 0 0 2 40 43 5 93.02325 -1.493 0.129 1 0004654 polyribonucleotide nucleotidyltransferase activity F 1 1 1 100 100 1 1 1 100 100 2.608 0.13 1 0044255 cellular lipid metabolic process P 0 0 0 0 0 8 37 69 21.62162 53.62319 1.618 0.13 1 0005975 carbohydrate metabolic process P 9 53 71 16.98113 74.64789 18 100 154 18 64.93507 1.592 0.13 1 0022613 ribonucleoprotein complex biogenesis and assembly P 0 0 0 0 0 6 27 28 22.22222 96.42857 1.472 0.13 1 0009307 DNA restriction-modification system P 1 1 1 100 100 1 1 1 100 100 2.608 0.131 1 0006878 cellular copper ion homeostasis P 1 1 1 100 100 1 1 1 100 100 2.608 0.131 1 0055070 copper ion homeostasis P 1 1 1 100 100 1 1 1 100 100 2.608 0.131 1 0004401 histidinol-phosphatase activity F 1 1 2 100 50 1 1 2 100 50 2.608 0.131 1 0005509 calcium ion binding F 2 5 8 40 62.5 2 5 8 40 62.5 1.821 0.131 1 0006812 cation transport P 0 14 14 0 100 4 64 80 6.25 80 -1.597 0.131 1 0051259 protein oligomerization P 0 0 0 0 0 1 1 1 100 100 2.608 0.132 1 0004332 fructose-bisphosphate aldolase activity F 1 1 1 100 100 1 1 1 100 100 2.608 0.132 1 0051262 protein tetramerization P 1 1 1 100 100 1 1 1 100 100 2.608 0.132 1 0019001 guanyl nucleotide binding F 0 0 0 0 0 6 25 29 24 86.20689 1.683 0.132 1 0005525 GTP binding F 6 25 29 24 86.20689 6 25 29 24 86.20689 1.683 0.132 1 0032561 guanyl ribonucleotide binding F 0 0 0 0 0 6 25 29 24 86.20689 1.683 0.132 1 0051604 protein maturation P 1 1 1 100 100 1 1 1 100 100 2.608 0.133 1 0008653 lipopolysaccharide metabolic process P 0 0 0 0 0 4 15 25 26.66667 60 1.611 0.133 1 0009103 lipopolysaccharide biosynthetic process P 3 8 15 37.5 53.33333 4 15 25 26.66667 60 1.611 0.133 1 0009094 L-phenylalanine biosynthetic process P 1 1 1 100 100 1 1 1 100 100 2.608 0.134 1 0004664 prephenate dehydratase activity F 1 1 1 100 100 1 1 1 100 100 2.608 0.134 1 0006811 ion transport P 2 23 36 8.695652 63.88889 6 84 103 7.142857 81.5534 -1.589 0.134 1 0065002 intracellular protein transmembrane transport P 3 10 10 30 100 3 10 10 30 100 1.63 0.135 1 0004655 porphobilinogen synthase activity F 1 1 1 100 100 1 1 1 100 100 2.608 0.136 1 0045893 positive regulation of transcription, DNA-dependent P 1 1 1 100 100 1 1 1 100 100 2.608 0.136 1 0004134 4-alpha-glucanotransferase activity F 1 1 1 100 100 1 1 1 100 100 2.608 0.136 1 0045913 positive regulation of carbohydrate metabolic process P 1 1 1 100 100 1 1 1 100 100 2.608 0.136 1 0047605 acetolactate decarboxylase activity F 1 1 1 100 100 1 1 1 100 100 2.608 0.136 1 0008816 citryl-CoA lyase activity F 1 1 1 100 100 1 1 1 100 100 2.608 0.137 1 0008815 citrate (pro-3S)-lyase activity F 1 1 1 100 100 1 1 1 100 100 2.608 0.137 1 0042803 protein homodimerization activity F 1 1 1 100 100 1 1 1 100 100 2.608 0.138 1 0030189 chaperone activator activity F 1 1 1 100 100 1 1 1 100 100 2.608 0.138 1 0000774 adenyl-nucleotide exchange factor activity F 1 1 1 100 100 1 1 1 100 100 2.608 0.138 1 0018065 protein-cofactor linkage P 0 0 0 0 0 1 1 2 100 50 2.608 0.139 1 0009249 protein lipoylation P 1 1 2 100 50 1 1 2 100 50 2.608 0.139 1 0008961 phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity F 1 1 1 100 100 1 1 1 100 100 2.608 0.139 1 0044262 cellular carbohydrate metabolic process P 0 1 3 0 33.33333 11 56 91 19.64286 61.53846 1.55 0.141 1 0004645 phosphorylase activity F 1 1 1 100 100 1 1 1 100 100 2.608 0.142 1 0004022 alcohol dehydrogenase activity F 1 1 1 100 100 1 1 1 100 100 2.608 0.143 1 0008774 acetaldehyde dehydrogenase (acetylating) activity F 1 1 1 100 100 1 1 1 100 100 2.608 0.143 1 0004523 ribonuclease H activity F 1 1 3 100 33.33333 1 1 3 100 33.33333 2.608 0.147 1 0016566 specific transcriptional repressor activity F 1 1 1 100 100 1 1 1 100 100 2.608 0.147 1 0016891 endoribonuclease activity, producing 5’-phosphomonoesters F 0 0 0 0 0 1 1 5 100 20 2.608 0.147 1 0004521 endoribonuclease activity F 0 0 0 0 0 1 1 5 100 20 2.608 0.147 1 0019109 acyl-CoA reductase activity F 1 1 1 100 100 1 1 1 100 100 2.608 0.148 1 0008218 bioluminescence P 1 1 1 100 100 1 1 1 100 100 2.608 0.148 1 0047474 long-chain-fatty-acid-luciferin-component ligase activity F 1 1 1 100 100 1 1 1 100 100 2.608 0.148 1 0031177 phosphopantetheine binding F 1 1 1 100 100 1 1 1 100 100 2.608 0.15 1 0000036 acyl carrier activity F 1 1 3 100 33.33333 1 1 3 100 33.33333 2.608 0.15 1 0019751 polyol metabolic process P 1 1 1 100 100 2 6 9 33.33333 66.66666 1.506 0.15 1 0030030 cell projection organization P 0 0 0 0 0 0 18 18 0 100 -1.634 0.151 1 0030174 regulation of DNA replication initiation P 0 0 0 0 0 1 1 1 100 100 2.608 0.154 1 0032297 negative regulation of DNA replication initiation P 1 1 1 100 100 1 1 1 100 100 2.608 0.154 1 0006520 amino acid metabolic process P 3 10 18 30 55.55556 11 56 158 19.64286 35.44304 1.55 0.16 1 0043414 biopolymer methylation P 0 0 0 0 0 2 6 8 33.33333 75 1.506 0.16 1 0020037 heme binding F 0 16 19 0 84.21053 0 16 19 0 84.21053 -1.539 0.162 1 0046906 tetrapyrrole binding F 0 0 0 0 0 0 16 19 0 84.21053 -1.539 0.162 1 0005618 cell wall C 0 0 1 0 0 2 42 47 4.761905 89.3617 -1.578 0.164 1 0009274 peptidoglycan-based cell wall C 0 1 2 0 50 2 42 46 4.761905 91.30434 -1.578 0.164 1 0003774 motor activity F 0 17 17 0 100 0 17 17 0 100 -1.587 0.164 1 0009276 Gram-negative-bacterium-type cell wall C 2 41 44 4.878049 93.18182 2 41 44 4.878049 93.18182 -1.536 0.165 1 0016072 rRNA metabolic process P 0 0 0 0 0 5 21 22 23.80952 95.45454 1.515 0.166 1 0006364 rRNA processing P 5 21 22 23.80952 95.45454 5 21 22 23.80952 95.45454 1.515 0.166 1 0006519 cellular amino acid and derivative metabolic process P 0 0 0 0 0 11 57 160 19.29825 35.625 1.486 0.168 1 0034641 cellular nitrogen compound metabolic process P 0 0 0 0 0 11 57 160 19.29825 35.625 1.486 0.168 1 0009308 cellular amine metabolic process P 0 0 0 0 0 11 57 160 19.29825 35.625 1.486 0.168 1 0043687 post-translational protein modification P 0 0 0 0 0 3 50 56 6 89.28571 -1.46 0.169 1 0006260 DNA replication P 6 23 31 26.08696 74.19355 7 32 42 21.875 76.19048 1.546 0.171 1 0009288 flagellin-based flagellum C 0 22 22 0 100 1 30 30 3.333333 100 -1.565 0.172 1 0051674 localization of cell P 0 0 0 0 0 1 28 28 3.571429 100 -1.473 0.174 1 0006928 cell motion P 0 8 8 0 100 1 28 28 3.571429 100 -1.473 0.174 1 0007154 cell communication P 0 0 0 0 0 20 204 211 9.803922 96.68246 -1.357 0.176 1 0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances F 0 6 15 0 40 1 31 49 3.225806 63.2653 -1.609 0.176 1 0004527 exonuclease activity F 3 12 15 25 80 5 20 26 25 76.92308 1.638 0.18 1 0008237 metallopeptidase activity F 3 13 16 23.07692 81.25 7 32 37 21.875 86.48649 1.546 0.181 1 0016209 antioxidant activity F 2 3 3 66.66666 100 2 6 8 33.33333 75 1.506 0.181 1 0008408 3’-5’ exonuclease activity F 1 4 6 25 66.66666 2 6 10 33.33333 60 1.506 0.181 1 0044260 cellular macromolecule metabolic process P 0 0 0 0 0 87 607 734 14.33278 82.69755 1.342 0.181 1 0042578 phosphoric ester hydrolase activity F 0 1 1 0 100 5 20 28 25 71.42857 1.638 0.182 1 0004175 endopeptidase activity F 0 0 0 0 0 7 35 40 20 87.5 1.283 0.182 1 0043170 macromolecule metabolic process P 0 0 0 0 0 88 616 747 14.28571 82.46319 1.315 0.184 1 0009070 serine family amino acid biosynthetic process P 0 0 0 0 0 2 6 11 33.33333 54.54546 1.506 0.185 1 0030001 metal ion transport P 0 4 6 0 66.66666 3 47 58 6.382979 81.03448 -1.335 0.186 1 0016830 carbon-carbon lyase activity F 1 1 2 100 50 5 21 46 23.80952 45.65217 1.515 0.188 1 0051540 metal cluster binding F 0 0 0 0 0 3 47 58 6.382979 81.03448 -1.335 0.188 1 0051536 iron-sulfur cluster binding F 2 41 52 4.878049 78.84615 3 47 58 6.382979 81.03448 -1.335 0.188 1 0008652 amino acid biosynthetic process P 1 11 62 9.090909 17.74194 7 34 88 20.58824 38.63636 1.368 0.189 1 0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups F 0 0 2 0 0 2 6 16 33.33333 37.5 1.506 0.19 1 0044265 cellular macromolecule catabolic process P 0 0 0 0 0 5 22 39 22.72727 56.41026 1.399 0.19 1 0050794 regulation of cellular process P 0 0 0 0 0 41 380 413 10.78947 92.00968 -1.312 0.19 1 0042254 ribosome biogenesis P 3 4 4 75 100 5 23 24 21.73913 95.83334 1.288 0.195 1 0016798 hydrolase activity, acting on glycosyl bonds F 1 4 7 25 57.14286 5 23 27 21.73913 85.18519 1.288 0.197 1 0065008 regulation of biological quality P 0 0 0 0 0 7 34 55 20.58824 61.81818 1.368 0.201 1 0008233 peptidase activity F 7 39 47 17.94872 82.97872 13 71 81 18.30986 87.65432 1.41 0.202 1 0008889 glycerophosphodiester phosphodiesterase activity F 1 2 2 50 100 1 2 2 50 100 1.574 0.204 1 0016407 acetyltransferase activity F 2 2 2 100 100 7 34 38 20.58824 89.47369 1.368 0.204 1 0009309 amine biosynthetic process P 0 0 0 0 0 7 35 91 20 38.46154 1.283 0.204 1 0044271 nitrogen compound biosynthetic process P 0 0 0 0 0 7 35 91 20 38.46154 1.283 0.204 1 0050789 regulation of biological process P 0 0 0 0 0 42 388 423 10.82474 91.72577 -1.306 0.205 1 0010033 response to organic substance P 1 1 1 100 100 1 2 2 50 100 1.574 0.211 1 0015893 drug transport P 0 0 0 0 0 2 7 7 28.57143 100 1.249 0.211 1 0042493 response to drug P 0 0 0 0 0 2 7 7 28.57143 100 1.249 0.211 1 0015238 drug transporter activity F 1 6 6 16.66667 100 2 7 7 28.57143 100 1.249 0.211 1 0003735 structural constituent of ribosome F 3 48 55 6.25 87.27273 3 48 55 6.25 87.27273 -1.377 0.216 1 0016787 hydrolase activity F 20 110 189 18.18182 58.20106 56 380 470 14.73684 80.85107 1.246 0.217 1 0001882 nucleoside binding F 2 7 7 28.57143 100 2 7 8 28.57143 87.5 1.249 0.218 1 0042364 water-soluble vitamin biosynthetic process P 0 0 0 0 0 1 25 44 4 56.81818 -1.327 0.219 1 0008649 rRNA methyltransferase activity F 1 3 3 33.33333 100 2 7 7 28.57143 100 1.249 0.222 1 0043364 catalysis of free radical formation F 0 0 0 0 0 1 2 2 50 100 1.574 0.223 1 0043365 [formate-C-acetyltransferase]-activating enzyme activity F 1 2 2 50 100 1 2 2 50 100 1.574 0.223 1 0008968 D-sedoheptulose 7-phosphate isomerase activity F 1 2 2 50 100 1 2 2 50 100 1.574 0.223 1 0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process P 1 7 11 14.28571 63.63636 48 432 564 11.11111 76.59574 -1.197 0.223 1 0016740 transferase activity F 30 184 323 16.30435 56.96594 45 300 443 15 67.72009 1.229 0.229 1 0017038 protein import P 1 2 2 50 100 1 2 2 50 100 1.574 0.23 1 0006570 tyrosine metabolic process P 0 1 1 0 100 1 2 3 50 66.66666 1.574 0.232 1 0009295 nucleoid C 1 2 2 50 100 1 2 2 50 100 1.574 0.233 1 0022804 active transmembrane transporter activity F 0 0 0 0 0 18 108 128 16.66667 84.375 1.231 0.233 1 0016301 kinase activity F 6 73 105 8.219178 69.52381 7 83 115 8.433735 72.17391 -1.219 0.233 1 0008616 queuosine biosynthetic process P 1 2 4 50 50 1 2 4 50 50 1.574 0.236 1 0046129 purine ribonucleoside biosynthetic process P 0 0 0 0 0 1 2 4 50 50 1.574 0.236 1 0046114 guanosine biosynthetic process P 0 0 0 0 0 1 2 4 50 50 1.574 0.236 1 0046118 7-methylguanosine biosynthetic process P 0 0 0 0 0 1 2 4 50 50 1.574 0.236 1 0009163 nucleoside biosynthetic process P 0 0 1 0 0 1 2 5 50 40 1.574 0.236 1 0008618 7-methylguanosine metabolic process P 0 0 0 0 0 1 2 4 50 50 1.574 0.236 1 0042455 ribonucleoside biosynthetic process P 0 0 0 0 0 1 2 4 50 50 1.574 0.236 1 0042451 purine nucleoside biosynthetic process P 0 0 0 0 0 1 2 4 50 50 1.574 0.236 1 0046116 queuosine metabolic process P 0 0 0 0 0 1 2 4 50 50 1.574 0.236 1 0000096 sulfur amino acid metabolic process P 0 0 0 0 0 2 7 18 28.57143 38.88889 1.249 0.237 1 0000097 sulfur amino acid biosynthetic process P 0 0 0 0 0 2 7 16 28.57143 43.75 1.249 0.237 1 0006510 ATP-dependent proteolysis P 1 2 2 50 100 1 2 2 50 100 1.574 0.238 1 0016044 membrane organization P 1 1 1 100 100 1 2 2 50 100 1.574 0.238 1 0009346 citrate lyase complex C 1 2 2 50 100 1 2 2 50 100 1.574 0.238 1 0009254 peptidoglycan turnover P 1 2 4 50 50 1 2 4 50 50 1.574 0.239 1 0004124 cysteine synthase activity F 1 2 2 50 100 1 2 2 50 100 1.574 0.239 1 0009374 biotin binding F 1 2 3 50 66.66666 1 2 3 50 66.66666 1.574 0.239 1 0043064 flagellum organization P 0 9 9 0 100 0 15 15 0 100 -1.49 0.239 1 0004616 phosphogluconate dehydrogenase (decarboxylating) activity F 1 2 2 50 100 1 2 2 50 100 1.574 0.24 1 0000175 3’-5’-exoribonuclease activity F 1 2 3 50 66.66666 1 2 3 50 66.66666 1.574 0.24 1 0042158 lipoprotein biosynthetic process P 1 2 2 50 100 1 2 2 50 100 1.574 0.241 1 0006558 L-phenylalanine metabolic process P 0 0 0 0 0 1 2 4 50 50 1.574 0.241 1 0005507 copper ion binding F 1 2 3 50 66.66666 1 2 3 50 66.66666 1.574 0.241 1 0042157 lipoprotein metabolic process P 0 0 0 0 0 1 2 2 50 100 1.574 0.241 1 0016837 carbon-oxygen lyase activity, acting on polysaccharides F 1 2 2 50 100 1 2 2 50 100 1.574 0.242 1 0004476 mannose-6-phosphate isomerase activity F 1 2 2 50 100 1 2 2 50 100 1.574 0.242 1 0030188 chaperone regulator activity F 0 1 1 0 100 1 2 2 50 100 1.574 0.243 1 0016436 rRNA (uridine) methyltransferase activity F 0 1 1 0 100 1 2 2 50 100 1.574 0.244 1 0050661 NADP binding F 2 7 16 28.57143 43.75 2 7 16 28.57143 43.75 1.249 0.246 1 0050896 response to stimulus P 0 0 0 0 0 14 146 163 9.589041 89.57055 -1.211 0.246 1 0043492 ATPase activity, coupled to movement of substances F 0 0 0 0 0 1 27 45 3.703704 60 -1.426 0.247 1 0042626 ATPase activity, coupled to transmembrane movement of substances F 1 18 19 5.555555 94.73684 1 27 45 3.703704 60 -1.426 0.247 1 0006402 mRNA catabolic process P 1 2 3 50 66.66666 1 2 3 50 66.66666 1.574 0.249 1 0016793 triphosphoric monoester hydrolase activity F 0 0 0 0 0 1 2 2 50 100 1.574 0.249 1 0008832 dGTPase activity F 1 2 2 50 100 1 2 2 50 100 1.574 0.249 1 0046039 GTP metabolic process P 1 2 2 50 100 1 2 3 50 66.66666 1.574 0.249 1 0065007 biological regulation P 0 0 0 0 0 44 400 436 11 91.74312 -1.214 0.25 1 0044432 endoplasmic reticulum part C 0 0 0 0 0 1 2 2 50 100 1.574 0.251 1 0042175 nuclear envelope-endoplasmic reticulum network C 0 0 0 0 0 1 2 2 50 100 1.574 0.251 1 0005789 endoplasmic reticulum membrane C 1 1 1 100 100 1 2 2 50 100 1.574 0.251 1 0012505 endomembrane system C 0 0 0 0 0 1 2 2 50 100 1.574 0.251 1 0042802 identical protein binding F 0 1 1 0 100 1 2 2 50 100 1.574 0.252 1 0009266 response to temperature stimulus P 0 0 0 0 0 1 2 2 50 100 1.574 0.252 1 0009408 response to heat P 1 2 2 50 100 1 2 2 50 100 1.574 0.252 1 0009628 response to abiotic stimulus P 0 0 0 0 0 1 2 2 50 100 1.574 0.252 1 0016832 aldehyde-lyase activity F 0 0 0 0 0 1 2 3 50 66.66666 1.574 0.253 1 0004133 glycogen debranching enzyme activity F 0 1 1 0 100 1 2 2 50 100 1.574 0.255 1 0004089 carbonate dehydratase activity F 1 2 2 50 100 1 2 2 50 100 1.574 0.255 1 0051301 cell division P 6 27 36 22.22222 75 6 28 37 21.42857 75.67567 1.373 0.255 1 0006164 purine nucleotide biosynthetic process P 0 2 12 0 16.66667 0 14 32 0 43.75 -1.439 0.255 1 0006109 regulation of carbohydrate metabolic process P 0 1 1 0 100 1 2 2 50 100 1.574 0.257 1 0051087 chaperone binding F 1 2 2 50 100 1 2 2 50 100 1.574 0.257 1 0006720 isoprenoid metabolic process P 0 0 0 0 0 1 2 9 50 22.22222 1.574 0.257 1 0008299 isoprenoid biosynthetic process P 1 2 9 50 22.22222 1 2 9 50 22.22222 1.574 0.257 1 0001539 ciliary or flagellar motility P 1 27 27 3.703704 100 1 27 27 3.703704 100 -1.426 0.258 1 0048870 cell motility P 0 0 0 0 0 1 27 27 3.703704 100 -1.426 0.258 1 0051053 negative regulation of DNA metabolic process P 0 0 0 0 0 1 2 2 50 100 1.574 0.259 1 0008156 negative regulation of DNA replication P 0 1 1 0 100 1 2 2 50 100 1.574 0.259 1 0033279 ribosomal subunit C 0 0 0 0 0 0 13 15 0 86.66666 -1.386 0.26 1 0005984 disaccharide metabolic process P 0 0 0 0 0 1 2 2 50 100 1.574 0.261 1 0005991 trehalose metabolic process P 1 1 1 100 100 1 2 2 50 100 1.574 0.261 1 0009260 ribonucleotide biosynthetic process P 0 0 0 0 0 0 12 28 0 42.85714 -1.332 0.261 1 0009152 purine ribonucleotide biosynthetic process P 0 1 1 0 100 0 12 26 0 46.15385 -1.332 0.261 1 0030246 carbohydrate binding F 0 14 15 0 93.33334 1 25 27 4 92.59259 -1.327 0.262 1 0015976 carbon utilization P 1 2 2 50 100 1 2 3 50 66.66666 1.574 0.265 1 0006396 RNA processing P 3 13 17 23.07692 76.47059 9 50 65 18 76.92308 1.111 0.268 1 0000156 two-component response regulator activity F 5 65 69 7.692307 94.2029 5 65 69 7.692307 94.2029 -1.256 0.268 1 0044275 cellular carbohydrate catabolic process P 0 0 0 0 0 4 18 28 22.22222 64.28571 1.199 0.271 1 0016866 intramolecular transferase activity F 1 4 4 25 100 4 19 27 21.05263 70.37037 1.079 0.274 1 0033692 cellular polysaccharide biosynthetic process P 0 0 0 0 0 4 18 32 22.22222 56.25 1.199 0.278 1 0006464 protein modification process P 0 2 7 0 28.57143 4 53 63 7.54717 84.12698 -1.162 0.279 1 0006725 cellular aromatic compound metabolic process P 1 1 1 100 100 6 31 68 19.35484 45.58823 1.098 0.284 1 0048037 cofactor binding F 2 6 8 33.33333 75 16 95 141 16.84211 67.37589 1.203 0.285 1 0051188 cofactor biosynthetic process P 0 1 1 0 100 4 51 89 7.843137 57.30337 -1.076 0.288 1 0010467 gene expression P 0 0 0 0 0 40 361 429 11.08033 84.14919 -1.089 0.288 1 0051186 cofactor metabolic process P 0 0 0 0 0 6 72 118 8.333333 61.01695 -1.158 0.288 1 0007165 signal transduction P 5 109 113 4.587156 96.46017 20 195 201 10.25641 97.01492 -1.125 0.29 1 0043283 biopolymer metabolic process P 0 0 0 0 0 84 599 717 14.02337 83.54254 1.059 0.293 1 0000271 polysaccharide biosynthetic process P 0 1 1 0 100 4 19 33 21.05263 57.57576 1.079 0.295 1 0034960 cellular biopolymer metabolic process P 0 0 0 0 0 83 593 710 13.99663 83.52113 1.028 0.297 1 0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity F 0 0 0 0 0 2 35 53 5.714286 66.03773 -1.268 0.299 1 0015399 primary active transmembrane transporter activity F 0 0 0 0 0 2 35 53 5.714286 66.03773 -1.268 0.299 1 0044464 cell part C 0 0 0 0 0 116 970 1212 11.95876 80.033 -1.113 0.302 1 0005623 cell C 0 0 0 0 0 116 970 1212 11.95876 80.033 -1.113 0.302 1 0005575 cellular_component C 0 0 0 0 0 118 985 1230 11.9797 80.0813 -1.102 0.306 1 0005840 ribosome C 4 51 58 7.843137 87.93104 4 51 58 7.843137 87.93104 -1.076 0.31 1 0017111 nucleoside-triphosphatase activity F 7 92 106 7.608696 86.79245 17 165 186 10.30303 88.70968 -1.007 0.314 1 0005506 iron ion binding F 4 46 67 8.695652 68.65672 4 51 72 7.843137 70.83334 -1.076 0.315 1 0008324 cation transmembrane transporter activity F 0 12 12 0 100 15 92 108 16.30435 85.18519 1.025 0.318 1 0016417 S-acyltransferase activity F 0 0 0 0 0 1 3 3 33.33333 100 1.064 0.325 1 0005415 nucleoside:sodium symporter activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 1.064 0.325 1 0046483 heterocycle metabolic process P 0 0 0 0 0 2 32 70 6.25 45.71429 -1.12 0.326 1 0000154 rRNA modification P 0 2 2 0 100 1 3 3 33.33333 100 1.064 0.327 1 0004743 pyruvate kinase activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 1.064 0.327 1 0006740 NADPH regeneration P 0 0 0 0 0 1 3 6 33.33333 50 1.064 0.329 1 0006739 NADP metabolic process P 0 0 1 0 0 1 3 7 33.33333 42.85714 1.064 0.329 1 0005783 endoplasmic reticulum C 0 1 1 0 100 1 3 3 33.33333 100 1.064 0.329 1 0006098 pentose-phosphate shunt P 1 3 5 33.33333 60 1 3 6 33.33333 50 1.064 0.329 1 0005496 steroid binding F 0 0 0 0 0 1 3 3 33.33333 100 1.064 0.331 1 0005498 sterol carrier activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 1.064 0.331 1 0032934 sterol binding F 0 0 0 0 0 1 3 3 33.33333 100 1.064 0.331 1 0006535 cysteine biosynthetic process from serine P 1 3 3 33.33333 100 1 3 3 33.33333 100 1.064 0.334 1 0016311 dephosphorylation P 0 1 2 0 50 1 3 4 33.33333 75 1.064 0.334 1 0006470 protein amino acid dephosphorylation P 1 3 3 33.33333 100 1 3 3 33.33333 100 1.064 0.334 1 0004725 protein tyrosine phosphatase activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 1.064 0.334 1 0030163 protein catabolic process P 1 2 4 50 50 1 3 5 33.33333 60 1.064 0.336 1 0009076 histidine family amino acid biosynthetic process P 0 0 0 0 0 1 3 10 33.33333 30 1.064 0.338 1 0009002 serine-type D-Ala-D-Ala carboxypeptidase activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 1.064 0.338 1 0000105 histidine biosynthetic process P 1 3 10 33.33333 30 1 3 10 33.33333 30 1.064 0.338 1 0006807 nitrogen compound metabolic process P 0 4 8 0 50 11 63 168 17.46032 37.5 1.121 0.34 1 0005524 ATP binding F 23 215 306 10.69767 70.26144 23 215 306 10.69767 70.26144 -0.983 0.34 1 0032559 adenyl ribonucleotide binding F 0 0 0 0 0 23 215 307 10.69767 70.03257 -0.983 0.34 1 0046873 metal ion transmembrane transporter activity F 0 3 4 0 75 1 22 27 4.545455 81.48148 -1.166 0.34 1 0004365 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity F 1 3 4 33.33333 75 1 3 4 33.33333 75 1.064 0.342 1 0006275 regulation of DNA replication P 0 1 1 0 100 1 3 3 33.33333 100 1.064 0.342 1 0008943 glyceraldehyde-3-phosphate dehydrogenase activity F 1 3 3 33.33333 100 1 3 4 33.33333 75 1.064 0.342 1 0003697 single-stranded DNA binding F 1 3 4 33.33333 75 1 3 4 33.33333 75 1.064 0.343 1 0006305 DNA alkylation P 0 0 0 0 0 1 3 5 33.33333 60 1.064 0.345 1 0006306 DNA methylation P 1 3 5 33.33333 60 1 3 5 33.33333 60 1.064 0.345 1 0006082 organic acid metabolic process P 0 0 2 0 0 15 91 226 16.48352 40.26549 1.072 0.346 1 0016071 mRNA metabolic process P 0 1 1 0 100 1 3 5 33.33333 60 1.064 0.347 1 0045941 positive regulation of transcription P 0 2 2 0 100 1 3 3 33.33333 100 1.064 0.348 1 0010557 positive regulation of macromolecule biosynthetic process P 0 0 0 0 0 1 3 3 33.33333 100 1.064 0.348 1 0009891 positive regulation of biosynthetic process P 0 0 0 0 0 1 3 3 33.33333 100 1.064 0.348 1 0010628 positive regulation of gene expression P 0 0 0 0 0 1 3 3 33.33333 100 1.064 0.348 1 0031328 positive regulation of cellular biosynthetic process P 0 0 0 0 0 1 3 3 33.33333 100 1.064 0.348 1 0016860 intramolecular oxidoreductase activity F 0 0 0 0 0 1 3 10 33.33333 30 1.064 0.349 1 0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses F 0 1 1 0 100 1 3 9 33.33333 33.33333 1.064 0.349 1 0044463 cell projection part C 0 0 0 0 0 1 22 22 4.545455 100 -1.166 0.35 1 0044461 flagellin-based flagellum part C 0 3 3 0 100 1 22 22 4.545455 100 -1.166 0.35 1 0044460 flagellum part C 0 0 0 0 0 1 22 22 4.545455 100 -1.166 0.35 1 0051254 positive regulation of RNA metabolic process P 0 0 0 0 0 1 3 3 33.33333 100 1.064 0.354 1 0006270 DNA replication initiation P 0 2 2 0 100 1 3 3 33.33333 100 1.064 0.355 1 0008235 metalloexopeptidase activity F 1 1 3 100 33.33333 1 3 5 33.33333 60 1.064 0.355 1 0030554 adenyl nucleotide binding F 0 0 0 0 0 26 241 337 10.78838 71.51335 -1.003 0.355 1 0006401 RNA catabolic process P 0 1 4 0 25 1 3 7 33.33333 42.85714 1.064 0.356 1 0044249 cellular biosynthetic process P 0 0 1 0 0 56 486 688 11.52263 70.63953 -0.98 0.356 1 0022900 electron transport chain P 1 12 15 8.333333 80 1 23 26 4.347826 88.46154 -1.222 0.356 1 0022904 respiratory electron transport chain P 0 7 7 0 100 0 11 11 0 100 -1.275 0.364 1 0015740 C4-dicarboxylate transport P 1 3 3 33.33333 100 1 3 3 33.33333 100 1.064 0.365 1 0015556 C4-dicarboxylate transmembrane transporter activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 1.064 0.365 1 0015074 DNA integration P 0 11 11 0 100 0 11 11 0 100 -1.275 0.365 1 0051287 NAD binding F 3 12 23 25 52.17391 3 12 23 25 52.17391 1.266 0.367 1 0043284 biopolymer biosynthetic process P 0 0 0 0 0 41 360 435 11.38889 82.75862 -0.894 0.368 1 0034961 cellular biopolymer biosynthetic process P 0 0 0 0 0 41 359 434 11.42061 82.71889 -0.872 0.37 1 0015103 inorganic anion transmembrane transporter activity F 0 0 0 0 0 0 11 15 0 73.33334 -1.275 0.376 1 0004536 deoxyribonuclease activity F 0 0 0 0 0 0 9 14 0 64.28571 -1.152 0.377 1 0008238 exopeptidase activity F 0 0 0 0 0 3 12 15 25 80 1.266 0.379 1 0006040 amino sugar metabolic process P 0 3 3 0 100 0 9 16 0 56.25 -1.152 0.38 1 0006119 oxidative phosphorylation P 0 0 0 0 0 0 10 15 0 66.66666 -1.215 0.382 1 0015980 energy derivation by oxidation of organic compounds P 0 0 0 0 0 0 11 19 0 57.89474 -1.275 0.384 1 0016655 oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor F 0 5 6 0 83.33334 0 8 9 0 88.88889 -1.086 0.39 1 0003678 DNA helicase activity F 0 2 2 0 100 0 9 9 0 100 -1.152 0.39 1 0045333 cellular respiration P 0 1 1 0 100 0 10 13 0 76.92308 -1.215 0.39 1 0016627 oxidoreductase activity, acting on the CH-CH group of donors F 0 4 4 0 100 3 14 18 21.42857 77.77778 0.968 0.395 1 0010382 cell wall metabolic process P 0 1 1 0 100 0 8 8 0 100 -1.086 0.396 1 0030031 cell projection assembly P 0 0 0 0 0 0 10 10 0 100 -1.215 0.399 1 0016879 ligase activity, forming carbon-nitrogen bonds F 0 1 1 0 100 0 8 33 0 24.24242 -1.086 0.401 1 0032259 methylation P 2 8 10 25 80 3 12 14 25 85.71429 1.266 0.402 1 0009060 aerobic respiration P 0 1 1 0 100 0 8 11 0 72.72727 -1.086 0.402 1 0006644 phospholipid metabolic process P 0 1 1 0 100 0 8 11 0 72.72727 -1.086 0.403 1 0006643 membrane lipid metabolic process P 0 0 0 0 0 0 8 11 0 72.72727 -1.086 0.403 1 0016769 transferase activity, transferring nitrogenous groups F 3 8 10 37.5 80 3 12 20 25 60 1.266 0.404 1 0009067 aspartate family amino acid biosynthetic process P 0 2 2 0 100 0 8 19 0 42.10526 -1.086 0.404 1 0006310 DNA recombination P 2 25 26 8 96.15385 2 28 31 7.142857 90.32258 -0.904 0.405 1 0006752 group transfer coenzyme metabolic process P 0 0 0 0 0 0 8 21 0 38.09524 -1.086 0.405 1 0003674 molecular_function F 0 0 0 0 0 229 1753 2169 13.06332 80.82066 0.904 0.406 1 0051128 regulation of cellular component organization P 0 0 0 0 0 0 8 24 0 33.33333 -1.086 0.406 1 0042724 thiamin and derivative biosynthetic process P 0 0 0 0 0 0 8 9 0 88.88889 -1.086 0.408 1 0006772 thiamin metabolic process P 0 0 0 0 0 0 8 9 0 88.88889 -1.086 0.408 1 0042723 thiamin and derivative metabolic process P 0 0 0 0 0 0 8 9 0 88.88889 -1.086 0.408 1 0009228 thiamin biosynthetic process P 0 8 9 0 88.88889 0 8 9 0 88.88889 -1.086 0.408 1 0016747 transferase activity, transferring acyl groups other than amino-acyl groups F 0 3 6 0 50 9 53 69 16.98113 76.81159 0.92 0.409 1 0030288 outer membrane-bounded periplasmic space C 2 31 33 6.451613 93.93939 2 31 33 6.451613 93.93939 -1.068 0.409 1 0006813 potassium ion transport P 0 8 8 0 100 0 8 8 0 100 -1.086 0.409 1 0008415 acyltransferase activity F 4 18 32 22.22222 56.25 9 52 68 17.30769 76.47059 0.982 0.412 1 0006631 fatty acid metabolic process P 0 1 5 0 20 3 14 25 21.42857 56 0.968 0.412 1 0009110 vitamin biosynthetic process P 0 0 0 0 0 2 30 50 6.666667 60 -1.015 0.412 1 0009108 coenzyme biosynthetic process P 0 0 0 0 0 2 29 56 6.896552 51.78571 -0.96 0.414 1 0009064 glutamine family amino acid metabolic process P 0 0 0 0 0 0 11 34 0 32.35294 -1.275 0.414 1 0034621 cellular macromolecular complex subunit organization P 0 0 0 0 0 2 28 30 7.142857 93.33334 -0.904 0.415 1 0004872 receptor activity F 0 8 8 0 100 0 8 8 0 100 -1.086 0.415 1 0015935 small ribosomal subunit C 0 8 8 0 100 0 8 8 0 100 -1.086 0.415 1 0031668 cellular response to extracellular stimulus P 0 0 0 0 0 0 9 10 0 90 -1.152 0.418 1 0009991 response to extracellular stimulus P 0 0 0 0 0 0 9 10 0 90 -1.152 0.418 1 0032984 macromolecular complex disassembly P 0 0 0 0 0 0 8 8 0 100 -1.086 0.42 1 0043624 cellular protein complex disassembly P 0 0 0 0 0 0 8 8 0 100 -1.086 0.42 1 0043241 protein complex disassembly P 0 0 0 0 0 0 8 8 0 100 -1.086 0.42 1 0022411 cellular component disassembly P 0 0 0 0 0 0 8 8 0 100 -1.086 0.42 1 0034623 cellular macromolecular complex disassembly P 0 0 0 0 0 0 8 8 0 100 -1.086 0.42 1 0006754 ATP biosynthetic process P 0 2 8 0 25 0 8 14 0 57.14286 -1.086 0.423 1 0009206 purine ribonucleoside triphosphate biosynthetic process P 0 0 0 0 0 0 8 15 0 53.33333 -1.086 0.423 1 0009145 purine nucleoside triphosphate biosynthetic process P 0 0 0 0 0 0 8 15 0 53.33333 -1.086 0.423 1 0009201 ribonucleoside triphosphate biosynthetic process P 0 0 0 0 0 0 8 15 0 53.33333 -1.086 0.423 1 0046034 ATP metabolic process P 0 0 2 0 0 0 8 14 0 57.14286 -1.086 0.423 1 0009142 nucleoside triphosphate biosynthetic process P 0 0 0 0 0 0 8 16 0 50 -1.086 0.423 1 0043234 protein complex C 0 1 1 0 100 5 55 83 9.090909 66.26506 -0.838 0.426 1 0009059 macromolecule biosynthetic process P 0 1 2 0 50 42 363 439 11.57025 82.68793 -0.784 0.429 1 0006767 water-soluble vitamin metabolic process P 0 0 0 0 0 2 28 51 7.142857 54.90196 -0.904 0.43 1 0000049 tRNA binding F 0 8 14 0 57.14286 0 8 14 0 57.14286 -1.086 0.433 1 0022890 inorganic cation transmembrane transporter activity F 0 0 0 0 0 2 31 41 6.451613 75.60976 -1.068 0.435 1 0016462 pyrophosphatase activity F 1 2 2 50 100 18 167 195 10.77844 85.64103 -0.822 0.451 1 0044444 cytoplasmic part C 0 0 0 0 0 11 68 86 16.17647 79.06977 0.844 0.458 1 0032991 macromolecular complex C 0 0 0 0 0 11 108 143 10.18519 75.52448 -0.84 0.462 1 0034470 ncRNA processing P 0 0 0 0 0 7 41 56 17.07317 73.21429 0.824 0.47 1 0016773 phosphotransferase activity, alcohol group as acceptor F 2 3 6 66.66666 50 12 77 94 15.58442 81.91489 0.742 0.474 1 0015672 monovalent inorganic cation transport P 0 1 1 0 100 3 36 47 8.333333 76.59574 -0.812 0.476 1 0034660 ncRNA metabolic process P 0 0 0 0 0 7 42 80 16.66667 52.5 0.755 0.481 1 0034645 cellular macromolecule biosynthetic process P 0 0 0 0 0 42 361 436 11.63435 82.79816 -0.741 0.483 1 0000041 transition metal ion transport P 0 0 0 0 0 1 16 20 6.25 80 -0.789 0.483 1 0022891 substrate-specific transmembrane transporter activity F 0 0 0 0 0 20 133 154 15.03759 86.36364 0.794 0.491 1 0051704 multi-organism process P 0 0 0 0 0 1 18 22 5.555555 81.81818 -0.925 0.493 1 0008509 anion transmembrane transporter activity F 0 0 0 0 0 1 18 22 5.555555 81.81818 -0.925 0.495 1 0034637 cellular carbohydrate biosynthetic process P 0 0 0 0 0 4 21 40 19.04762 52.5 0.859 0.498 1 0003677 DNA binding F 29 229 249 12.66376 91.96787 31 270 292 11.48148 92.46575 -0.704 0.498 1 0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor F 2 9 14 22.22222 64.28571 4 20 38 20 52.63158 0.966 0.5 1 0046915 transition metal ion transmembrane transporter activity F 0 0 0 0 0 1 16 18 6.25 88.88889 -0.789 0.501 1 0015082 di-, tri-valent inorganic cation transmembrane transporter activity F 0 0 0 0 0 1 16 18 6.25 88.88889 -0.789 0.501 1 0055085 transmembrane transport P 0 0 0 0 0 4 21 26 19.04762 80.76923 0.859 0.504 1 0016052 carbohydrate catabolic process P 0 0 1 0 0 4 21 32 19.04762 65.625 0.859 0.504 1 0044403 symbiosis, encompassing mutualism through parasitism P 0 0 0 0 0 1 16 19 6.25 84.21053 -0.789 0.504 1 0044419 interspecies interaction between organisms P 0 0 0 0 0 1 16 19 6.25 84.21053 -0.789 0.504 1 0006163 purine nucleotide metabolic process P 0 0 2 0 0 1 16 36 6.25 44.44444 -0.789 0.507 1 0051716 cellular response to stimulus P 0 0 0 0 0 4 44 51 9.090909 86.27451 -0.747 0.511 1 0007047 cell wall organization P 1 6 22 16.66667 27.27273 1 16 32 6.25 50 -0.789 0.518 1 0006732 coenzyme metabolic process P 0 0 0 0 0 4 45 79 8.888889 56.96202 -0.797 0.519 1 0044446 intracellular organelle part C 0 0 0 0 0 1 18 23 5.555555 78.26087 -0.925 0.522 1 0044422 organelle part C 0 0 0 0 0 1 18 23 5.555555 78.26087 -0.925 0.522 1 0016614 oxidoreductase activity, acting on CH-OH group of donors F 0 0 1 0 0 4 22 42 18.18182 52.38095 0.757 0.523 1 0033554 cellular response to stress P 0 0 0 0 0 4 43 50 9.302325 86 -0.696 0.525 1 0044248 cellular catabolic process P 0 0 0 0 0 8 50 90 16 55.55556 0.682 0.532 1 0042623 ATPase activity, coupled F 0 0 0 0 0 5 52 70 9.615385 74.28571 -0.699 0.532 1 0015075 ion transmembrane transporter activity F 0 1 1 0 100 16 108 128 14.81481 84.375 0.64 0.535 1 0050660 FAD binding F 2 25 29 8 86.20689 2 25 29 8 86.20689 -0.725 0.537 1 0016817 hydrolase activity, acting on acid anhydrides F 0 0 0 0 0 19 169 198 11.2426 85.35354 -0.639 0.538 1 0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides F 2 7 7 28.57143 100 19 169 198 11.2426 85.35354 -0.639 0.538 1 0019752 carboxylic acid metabolic process P 0 3 4 0 75 14 90 223 15.55556 40.35875 0.796 0.539 1 0006091 generation of precursor metabolites and energy P 0 1 1 0 100 4 44 67 9.090909 65.67164 -0.747 0.542 1 0005976 polysaccharide metabolic process P 0 0 1 0 0 4 23 37 17.3913 62.16216 0.66 0.543 1 0044264 cellular polysaccharide metabolic process P 0 0 0 0 0 4 23 37 17.3913 62.16216 0.66 0.543 1 0003676 nucleic acid binding F 11 55 71 20 77.46479 54 391 438 13.81074 89.26941 0.658 0.545 1 0009056 catabolic process P 0 0 0 0 0 9 55 99 16.36364 55.55556 0.798 0.547 1 0051641 cellular localization P 0 0 0 0 0 5 54 54 9.259259 100 -0.792 0.55 1 0051649 establishment of localization in cell P 0 0 0 0 0 5 53 53 9.433962 100 -0.746 0.554 1 0016874 ligase activity F 3 17 67 17.64706 25.37313 5 28 81 17.85714 34.5679 0.804 0.565 1 0043228 non-membrane-bounded organelle C 0 0 0 0 0 6 61 72 9.836065 84.72222 -0.707 0.568 1 0043232 intracellular non-membrane-bounded organelle C 0 0 0 0 0 6 61 72 9.836065 84.72222 -0.707 0.568 1 0009310 amine catabolic process P 0 0 0 0 0 0 6 18 0 33.33333 -0.94 0.582 1 0009063 amino acid catabolic process P 0 0 0 0 0 0 6 18 0 33.33333 -0.94 0.582 1 0044270 nitrogen compound catabolic process P 0 0 0 0 0 0 6 18 0 33.33333 -0.94 0.582 1 0030234 enzyme regulator activity F 0 3 3 0 100 0 6 6 0 100 -0.94 0.584 1 0046467 membrane lipid biosynthetic process P 0 0 0 0 0 0 7 10 0 70 -1.016 0.59 1 0008654 phospholipid biosynthetic process P 0 7 10 0 70 0 7 10 0 70 -1.016 0.59 1 0009117 nucleotide metabolic process P 1 1 5 100 20 5 31 75 16.12903 41.33333 0.556 0.592 1 0006753 nucleoside phosphate metabolic process P 0 0 0 0 0 5 31 75 16.12903 41.33333 0.556 0.592 1 0006099 tricarboxylic acid cycle P 0 7 10 0 70 0 7 10 0 70 -1.016 0.592 1 0009109 coenzyme catabolic process P 0 0 0 0 0 0 7 11 0 63.63636 -1.016 0.592 1 0051187 cofactor catabolic process P 0 0 0 0 0 0 7 11 0 63.63636 -1.016 0.592 1 0046356 acetyl-CoA catabolic process P 0 0 0 0 0 0 7 10 0 70 -1.016 0.592 1 0043229 intracellular organelle C 0 0 0 0 0 7 67 80 10.44776 83.75 -0.589 0.594 1 0043226 organelle C 0 0 0 0 0 7 68 81 10.29412 83.95061 -0.632 0.596 1 0016998 cell wall catabolic process P 0 7 7 0 100 0 7 7 0 100 -1.016 0.596 1 0008094 DNA-dependent ATPase activity F 0 1 1 0 100 0 7 7 0 100 -1.016 0.597 1 0009058 biosynthetic process P 8 31 55 25.80645 56.36364 62 515 739 12.03883 69.68877 -0.611 0.598 1 0044459 plasma membrane part C 0 0 0 0 0 0 5 5 0 100 -0.858 0.598 1 0009081 branched chain family amino acid metabolic process P 0 1 1 0 100 0 6 12 0 50 -0.94 0.598 1 0006768 biotin metabolic process P 0 0 0 0 0 0 5 7 0 71.42857 -0.858 0.6 1 0009102 biotin biosynthetic process P 0 5 7 0 71.42857 0 5 7 0 71.42857 -0.858 0.6 1 0046983 protein dimerization activity F 1 7 13 14.28571 53.84615 2 8 14 25 57.14286 1.033 0.601 1 0009069 serine family amino acid metabolic process P 0 0 2 0 0 2 8 18 25 44.44444 1.033 0.605 1 0032268 regulation of cellular protein metabolic process P 0 0 0 0 0 0 7 7 0 100 -1.016 0.607 1 0051246 regulation of protein metabolic process P 0 0 0 0 0 0 7 7 0 100 -1.016 0.607 1 0031504 peptidoglycan-based cell wall organization P 0 0 0 0 0 0 5 21 0 23.80952 -0.858 0.608 1 0042546 cell wall biogenesis P 0 0 0 0 0 0 5 21 0 23.80952 -0.858 0.608 1 0009273 peptidoglycan-based cell wall biogenesis P 0 4 8 0 50 0 5 21 0 23.80952 -0.858 0.608 1 0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer F 0 1 3 0 33.33333 0 4 6 0 66.66666 -0.767 0.609 1 0004520 endodeoxyribonuclease activity F 0 0 1 0 0 0 5 8 0 62.5 -0.858 0.609 1 0016831 carboxy-lyase activity F 1 7 20 14.28571 35 2 10 26 20 38.46154 0.681 0.61 1 0006353 transcription termination P 0 4 4 0 100 0 5 5 0 100 -0.858 0.61 1 0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor F 0 1 4 0 25 2 8 16 25 50 1.033 0.612 1 0043623 cellular protein complex assembly P 0 0 0 0 0 0 7 9 0 77.77778 -1.016 0.612 1 0006744 ubiquinone biosynthetic process P 0 7 9 0 77.77778 0 7 9 0 77.77778 -1.016 0.613 1 0006743 ubiquinone metabolic process P 0 0 0 0 0 0 7 9 0 77.77778 -1.016 0.613 1 0006835 dicarboxylic acid transport P 1 5 5 20 100 2 8 8 25 100 1.033 0.614 1 0005310 dicarboxylic acid transmembrane transporter activity F 0 0 0 0 0 2 8 8 25 100 1.033 0.614 1 0048519 negative regulation of biological process P 0 0 0 0 0 2 9 11 22.22222 81.81818 0.846 0.615 1 0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process P 0 0 0 0 0 2 9 11 22.22222 81.81818 0.846 0.615 1 0048523 negative regulation of cellular process P 0 0 0 0 0 2 9 11 22.22222 81.81818 0.846 0.615 1 0031327 negative regulation of cellular biosynthetic process P 0 0 0 0 0 2 9 11 22.22222 81.81818 0.846 0.615 1 0031324 negative regulation of cellular metabolic process P 0 0 0 0 0 2 9 11 22.22222 81.81818 0.846 0.615 1 0010558 negative regulation of macromolecule biosynthetic process P 0 0 0 0 0 2 9 11 22.22222 81.81818 0.846 0.615 1 0009890 negative regulation of biosynthetic process P 0 0 0 0 0 2 9 11 22.22222 81.81818 0.846 0.615 1 0009892 negative regulation of metabolic process P 0 0 0 0 0 2 9 11 22.22222 81.81818 0.846 0.615 1 0010605 negative regulation of macromolecule metabolic process P 0 0 0 0 0 2 9 11 22.22222 81.81818 0.846 0.615 1 0046348 amino sugar catabolic process P 0 2 2 0 100 0 6 6 0 100 -0.94 0.615 1 0009432 SOS response P 0 7 8 0 87.5 0 7 8 0 87.5 -1.016 0.615 1 0000272 polysaccharide catabolic process P 0 0 0 0 0 0 5 5 0 100 -0.858 0.618 1 0044247 cellular polysaccharide catabolic process P 0 0 0 0 0 0 5 5 0 100 -0.858 0.618 1 0004003 ATP-dependent DNA helicase activity F 0 6 6 0 100 0 6 6 0 100 -0.94 0.618 1 0043176 amine binding F 0 0 0 0 0 2 10 13 20 76.92308 0.681 0.619 1 0016597 amino acid binding F 2 10 13 20 76.92308 2 10 13 20 76.92308 0.681 0.619 1 0009420 flagellin-based flagellum filament C 0 5 5 0 100 0 5 5 0 100 -0.858 0.62 1 0006817 phosphate transport P 0 6 8 0 75 0 6 8 0 75 -0.94 0.62 1 0016780 phosphotransferase activity, for other substituted phosphate groups F 0 5 5 0 100 0 6 9 0 66.66666 -0.94 0.621 1 0016638 oxidoreductase activity, acting on the CH-NH2 group of donors F 0 0 0 0 0 0 5 8 0 62.5 -0.858 0.623 1 0017004 cytochrome complex assembly P 0 5 7 0 71.42857 0 5 7 0 71.42857 -0.858 0.624 1 0016469 proton-transporting two-sector ATPase complex C 0 0 2 0 0 0 6 11 0 54.54546 -0.94 0.625 1 0015985 energy coupled proton transport, down electrochemical gradient P 0 0 0 0 0 0 6 11 0 54.54546 -0.94 0.625 1 0015986 ATP synthesis coupled proton transport P 0 6 11 0 54.54546 0 6 11 0 54.54546 -0.94 0.625 1 0006766 vitamin metabolic process P 0 0 0 0 0 3 33 57 9.090909 57.89474 -0.645 0.626 1 0006760 folic acid and derivative metabolic process P 0 1 1 0 100 0 7 13 0 53.84615 -1.016 0.626 1 0009296 flagellum assembly P 0 7 7 0 100 0 7 7 0 100 -1.016 0.626 1 0016857 racemase and epimerase activity, acting on carbohydrates and derivatives F 0 2 3 0 66.66666 0 5 7 0 71.42857 -0.858 0.627 1 0016854 racemase and epimerase activity F 0 0 0 0 0 0 5 13 0 38.46154 -0.858 0.627 1 0015197 peptide transporter activity F 0 5 5 0 100 0 5 5 0 100 -0.858 0.628 1 0022892 substrate-specific transporter activity F 0 0 0 0 0 21 180 204 11.66667 88.23529 -0.483 0.63 1 0046493 lipid A metabolic process P 0 0 0 0 0 0 4 7 0 57.14286 -0.767 0.63 1 0009245 lipid A biosynthetic process P 0 4 7 0 57.14286 0 4 7 0 57.14286 -0.767 0.63 1 0045892 negative regulation of transcription, DNA-dependent P 0 4 5 0 80 0 5 6 0 83.33334 -0.858 0.63 1 0051253 negative regulation of RNA metabolic process P 0 0 0 0 0 0 5 6 0 83.33334 -0.858 0.63 1 0051537 2 iron, 2 sulfur cluster binding F 0 5 6 0 83.33334 0 5 6 0 83.33334 -0.858 0.631 1 0005694 chromosome C 2 10 13 20 76.92308 2 10 14 20 71.42857 0.681 0.632 1 0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors F 0 1 1 0 100 2 10 18 20 55.55556 0.681 0.634 1 0008360 regulation of cell shape P 0 5 21 0 23.80952 0 5 21 0 23.80952 -0.858 0.634 1 0022604 regulation of cell morphogenesis P 0 0 0 0 0 0 5 21 0 23.80952 -0.858 0.634 1 0022603 regulation of anatomical structure morphogenesis P 0 0 0 0 0 0 5 21 0 23.80952 -0.858 0.634 1 0050793 regulation of developmental process P 0 0 0 0 0 0 5 21 0 23.80952 -0.858 0.634 1 0006044 N-acetylglucosamine metabolic process P 0 1 4 0 25 0 6 9 0 66.66666 -0.94 0.634 1 0006041 glucosamine metabolic process P 0 0 0 0 0 0 6 9 0 66.66666 -0.94 0.634 1 0009116 nucleoside metabolic process P 1 6 13 16.66667 46.15385 2 10 23 20 43.47826 0.681 0.635 1 0009396 folic acid and derivative biosynthetic process P 0 6 9 0 66.66666 0 6 12 0 50 -0.94 0.635 1 0016895 exodeoxyribonuclease activity, producing 5’-phosphomonoesters F 0 0 0 0 0 0 4 6 0 66.66666 -0.767 0.64 1 0004529 exodeoxyribonuclease activity F 0 0 0 0 0 0 4 6 0 66.66666 -0.767 0.64 1 0003916 DNA topoisomerase activity F 0 5 8 0 62.5 0 5 8 0 62.5 -0.858 0.64 1 0015114 phosphate transmembrane transporter activity F 0 2 4 0 50 0 5 7 0 71.42857 -0.858 0.642 1 0042773 ATP synthesis coupled electron transport P 0 4 4 0 100 0 4 4 0 100 -0.767 0.643 1 0006417 regulation of translation P 0 4 4 0 100 0 5 5 0 100 -0.858 0.644 1 0010608 posttranscriptional regulation of gene expression P 0 0 0 0 0 0 5 5 0 100 -0.858 0.644 1 0042625 ATPase activity, coupled to transmembrane movement of ions F 0 0 0 0 0 0 5 15 0 33.33333 -0.858 0.646 1 0009084 glutamine family amino acid biosynthetic process P 0 0 0 0 0 0 6 19 0 31.57895 -0.94 0.647 1 0031226 intrinsic to plasma membrane C 0 0 0 0 0 0 4 4 0 100 -0.767 0.648 1 0005887 integral to plasma membrane C 0 3 3 0 100 0 4 4 0 100 -0.767 0.648 1 0005416 cation:amino acid symporter activity F 0 0 0 0 0 0 5 5 0 100 -0.858 0.648 1 0005283 sodium:amino acid symporter activity F 0 3 3 0 100 0 5 5 0 100 -0.858 0.648 1 0015934 large ribosomal subunit C 0 5 7 0 71.42857 0 5 7 0 71.42857 -0.858 0.649 1 0043285 biopolymer catabolic process P 0 0 0 0 0 2 11 19 18.18182 57.89474 0.534 0.65 1 0009289 fimbrium C 0 4 4 0 100 0 4 4 0 100 -0.767 0.65 1 0003684 damaged DNA binding F 0 4 6 0 66.66666 0 4 6 0 66.66666 -0.767 0.65 1 0032196 transposition P 0 2 2 0 100 0 5 7 0 71.42857 -0.858 0.65 1 0006313 transposition, DNA-mediated P 0 5 7 0 71.42857 0 5 7 0 71.42857 -0.858 0.65 1 0016782 transferase activity, transferring sulfur-containing groups F 0 0 0 0 0 0 4 10 0 40 -0.767 0.651 1 0004568 chitinase activity F 0 4 4 0 100 0 4 4 0 100 -0.767 0.652 1 0006046 N-acetylglucosamine catabolic process P 0 0 0 0 0 0 4 4 0 100 -0.767 0.652 1 0006030 chitin metabolic process P 0 0 0 0 0 0 4 4 0 100 -0.767 0.652 1 0006043 glucosamine catabolic process P 0 0 0 0 0 0 4 4 0 100 -0.767 0.652 1 0006032 chitin catabolic process P 0 4 4 0 100 0 4 4 0 100 -0.767 0.652 1 0030694 flagellin-based flagellum basal body, rod C 0 1 1 0 100 0 4 4 0 100 -0.767 0.652 1 0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen F 0 4 4 0 100 0 4 4 0 100 -0.767 0.653 1 0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen F 0 0 0 0 0 0 4 4 0 100 -0.767 0.653 1 0051213 dioxygenase activity F 0 0 0 0 0 0 4 5 0 80 -0.767 0.653 1 0050801 ion homeostasis P 0 0 0 0 0 2 10 10 20 100 0.681 0.656 1 0055080 cation homeostasis P 0 0 0 0 0 2 10 10 20 100 0.681 0.656 1 0048878 chemical homeostasis P 0 0 0 0 0 2 10 10 20 100 0.681 0.656 1 0006281 DNA repair P 4 40 47 10 85.10638 4 41 48 9.756098 85.41666 -0.592 0.659 1 0034984 cellular response to DNA damage stimulus P 0 0 0 0 0 4 41 48 9.756098 85.41666 -0.592 0.659 1 0006974 response to DNA damage stimulus P 3 16 23 18.75 69.56522 4 41 48 9.756098 85.41666 -0.592 0.659 1 0004091 carboxylesterase activity F 0 1 2 0 50 0 4 9 0 44.44444 -0.767 0.659 1 0009082 branched chain family amino acid biosynthetic process P 0 3 9 0 33.33333 0 4 10 0 40 -0.767 0.66 1 0006265 DNA topological change P 0 4 7 0 57.14286 0 4 7 0 57.14286 -0.767 0.66 1 0005886 plasma membrane C 24 200 239 12 83.68201 24 205 244 11.70732 84.0164 -0.5 0.661 1 0015232 heme transporter activity F 0 3 3 0 100 0 4 5 0 80 -0.767 0.663 1 0051181 cofactor transport P 0 0 0 0 0 0 4 4 0 100 -0.767 0.663 1 0051184 cofactor transporter activity F 0 0 0 0 0 0 4 5 0 80 -0.767 0.663 1 0009112 nucleobase metabolic process P 0 0 0 0 0 0 4 14 0 28.57143 -0.767 0.663 1 0015886 heme transport P 0 4 4 0 100 0 4 4 0 100 -0.767 0.663 1 0046112 nucleobase biosynthetic process P 0 0 0 0 0 0 4 10 0 40 -0.767 0.663 1 0045259 proton-transporting ATP synthase complex C 0 0 0 0 0 0 4 9 0 44.44444 -0.767 0.666 1 0005315 inorganic phosphate transmembrane transporter activity F 0 4 6 0 66.66666 0 4 6 0 66.66666 -0.767 0.666 1 0009168 purine ribonucleoside monophosphate biosynthetic process P 0 0 1 0 0 0 4 11 0 36.36364 -0.767 0.667 1 0009156 ribonucleoside monophosphate biosynthetic process P 0 0 1 0 0 0 4 13 0 30.76923 -0.767 0.667 1 0009124 nucleoside monophosphate biosynthetic process P 0 0 0 0 0 0 4 14 0 28.57143 -0.767 0.667 1 0009127 purine nucleoside monophosphate biosynthetic process P 0 0 0 0 0 0 4 11 0 36.36364 -0.767 0.667 1 0009161 ribonucleoside monophosphate metabolic process P 0 0 0 0 0 0 4 13 0 30.76923 -0.767 0.667 1 0009123 nucleoside monophosphate metabolic process P 0 0 0 0 0 0 4 14 0 28.57143 -0.767 0.667 1 0009167 purine ribonucleoside monophosphate metabolic process P 0 0 0 0 0 0 4 11 0 36.36364 -0.767 0.667 1 0009126 purine nucleoside monophosphate metabolic process P 0 0 0 0 0 0 4 11 0 36.36364 -0.767 0.667 1 0051180 vitamin transport P 0 0 0 0 0 0 4 5 0 80 -0.767 0.669 1 0016298 lipase activity F 0 2 2 0 100 0 4 5 0 80 -0.767 0.669 1 0019835 cytolysis P 0 4 4 0 100 0 4 4 0 100 -0.767 0.67 1 0002097 tRNA wobble base modification P 0 1 1 0 100 0 4 4 0 100 -0.767 0.67 1 0016265 death P 0 0 0 0 0 0 4 4 0 100 -0.767 0.67 1 0008219 cell death P 0 0 0 0 0 0 4 4 0 100 -0.767 0.67 1 0004072 aspartate kinase activity F 0 4 4 0 100 0 4 4 0 100 -0.767 0.671 1 0019202 amino acid kinase activity F 0 0 0 0 0 0 4 6 0 66.66666 -0.767 0.671 1 0016774 phosphotransferase activity, carboxyl group as acceptor F 0 0 2 0 0 0 4 9 0 44.44444 -0.767 0.671 1 0006537 glutamate biosynthetic process P 0 4 4 0 100 0 4 4 0 100 -0.767 0.676 1 0006536 glutamate metabolic process P 0 0 0 0 0 0 4 7 0 57.14286 -0.767 0.676 1 0004497 monooxygenase activity F 0 4 5 0 80 0 4 5 0 80 -0.767 0.677 1 0043565 sequence-specific DNA binding F 5 47 49 10.6383 95.91837 5 47 49 10.6383 95.91837 -0.452 0.678 1 0010181 FMN binding F 1 14 18 7.142857 77.77778 1 14 18 7.142857 77.77778 -0.637 0.684 1 0051183 vitamin transporter activity F 0 0 0 0 0 0 4 6 0 66.66666 -0.767 0.684 1 0015235 cobalamin transporter activity F 0 2 2 0 100 0 4 6 0 66.66666 -0.767 0.684 1 0017076 purine nucleotide binding F 0 0 1 0 0 32 266 366 12.03008 72.6776 -0.411 0.686 1 0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen F 0 0 0 0 0 0 4 6 0 66.66666 -0.767 0.686 1 0008173 RNA methyltransferase activity F 2 9 10 22.22222 90 3 16 20 18.75 80 0.713 0.693 1 0006826 iron ion transport P 0 8 11 0 72.72727 1 14 17 7.142857 82.35294 -0.637 0.693 1 0015674 di-, tri-valent inorganic cation transport P 0 0 0 0 0 1 14 17 7.142857 82.35294 -0.637 0.693 1 0004553 hydrolase activity, hydrolyzing O-glycosyl compounds F 3 17 19 17.64706 89.47369 3 18 21 16.66667 85.71429 0.491 0.698 1 0008168 methyltransferase activity F 5 45 62 11.11111 72.58064 5 50 71 10 70.42254 -0.603 0.698 1 0016741 transferase activity, transferring one-carbon groups F 0 0 0 0 0 5 50 73 10 68.49315 -0.603 0.698 1 0009259 ribonucleotide metabolic process P 0 0 0 0 0 1 14 30 7.142857 46.66667 -0.637 0.702 1 0009150 purine ribonucleotide metabolic process P 0 0 0 0 0 1 14 28 7.142857 50 -0.637 0.702 1 0005381 iron ion transmembrane transporter activity F 1 7 7 14.28571 100 1 14 15 7.142857 93.33334 -0.637 0.705 1 0006820 anion transport P 0 0 0 0 0 1 15 19 6.666667 78.94736 -0.715 0.709 1 0008134 transcription factor binding F 1 14 14 7.142857 100 1 14 14 7.142857 100 -0.637 0.71 1 0009425 flagellin-based flagellum basal body C 1 9 9 11.11111 100 1 12 12 8.333333 100 -0.466 0.714 1 0009405 pathogenesis P 1 15 18 6.666667 83.33334 1 15 18 6.666667 83.33334 -0.715 0.714 1 0015036 disulfide oxidoreductase activity F 0 1 1 0 100 1 12 13 8.333333 92.30769 -0.466 0.715 1 0016746 transferase activity, transferring acyl groups F 0 0 0 0 0 9 59 77 15.25424 76.62337 0.569 0.716 1 0015698 inorganic anion transport P 0 0 0 0 0 1 14 18 7.142857 77.77778 -0.637 0.717 1 0015078 hydrogen ion transmembrane transporter activity F 0 3 8 0 37.5 1 13 19 7.692307 68.42105 -0.554 0.719 1 0015628 protein secretion by the type II secretion system P 1 15 15 6.666667 100 1 15 15 6.666667 100 -0.715 0.719 1 0015627 type II protein secretion system complex C 1 15 15 6.666667 100 1 15 15 6.666667 100 -0.715 0.719 1 0016667 oxidoreductase activity, acting on sulfur group of donors F 0 0 0 0 0 1 14 24 7.142857 58.33333 -0.637 0.721 1 0006779 porphyrin biosynthetic process P 0 4 10 0 40 1 13 22 7.692307 59.09091 -0.554 0.725 1 0006778 porphyrin metabolic process P 0 0 0 0 0 1 13 22 7.692307 59.09091 -0.554 0.725 1 0015077 monovalent inorganic cation transmembrane transporter activity F 0 0 0 0 0 1 15 23 6.666667 65.21739 -0.715 0.732 1 0005275 amine transmembrane transporter activity F 0 0 0 0 0 1 12 13 8.333333 92.30769 -0.466 0.734 1 0016051 carbohydrate biosynthetic process P 0 1 2 0 50 4 25 58 16 43.10345 0.479 0.735 1 0006814 sodium ion transport P 2 20 26 10 76.92308 2 20 26 10 76.92308 -0.378 0.74 1 0006733 oxidoreduction coenzyme metabolic process P 0 0 0 0 0 1 12 22 8.333333 54.54546 -0.466 0.743 1 0051539 4 iron, 4 sulfur cluster binding F 3 18 24 16.66667 75 3 18 24 16.66667 75 0.491 0.748 1 0015837 amine transport P 0 0 0 0 0 2 21 23 9.523809 91.30434 -0.453 0.753 1 0006865 amino acid transport P 2 18 19 11.11111 94.73684 2 21 22 9.523809 95.45454 -0.453 0.753 1 0016779 nucleotidyltransferase activity F 1 10 32 10 31.25 2 23 45 8.695652 51.11111 -0.594 0.757 1 0000166 nucleotide binding F 23 153 244 15.03268 62.70492 36 293 400 12.28669 73.25 -0.292 0.758 1 0043933 macromolecular complex subunit organization P 0 0 0 0 0 3 29 31 10.34483 93.54839 -0.401 0.761 1 0006399 tRNA metabolic process P 0 0 0 0 0 2 22 59 9.090909 37.28814 -0.525 0.767 1 0032553 ribonucleotide binding F 0 0 0 0 0 29 240 336 12.08333 71.42857 -0.361 0.768 1 0032555 purine ribonucleotide binding F 0 0 0 0 0 29 240 336 12.08333 71.42857 -0.361 0.768 1 0008033 tRNA processing P 1 18 31 5.555555 58.06452 2 21 35 9.523809 60 -0.453 0.768 1 0070035 purine NTP-dependent helicase activity F 0 0 0 0 0 2 20 20 10 100 -0.378 0.772 1 0008026 ATP-dependent helicase activity F 2 16 16 12.5 100 2 20 20 10 100 -0.378 0.772 1 0005576 extracellular region C 2 21 26 9.523809 80.76923 2 22 27 9.090909 81.48148 -0.525 0.774 1 0034622 cellular macromolecular complex assembly P 0 0 0 0 0 2 20 22 10 90.90909 -0.378 0.788 1 0016410 N-acyltransferase activity F 0 1 1 0 100 3 31 35 9.67742 88.57143 -0.526 0.8 1 0022857 transmembrane transporter activity F 0 0 0 0 0 21 155 179 13.54839 86.59218 0.285 0.803 1 0008080 N-acetyltransferase activity F 3 29 32 10.34483 90.625 3 29 33 10.34483 87.87878 -0.401 0.805 1 0032787 monocarboxylic acid metabolic process P 0 0 0 0 0 3 30 57 10 52.63158 -0.465 0.812 1 0030529 ribonucleoprotein complex C 3 48 55 6.25 87.27273 6 53 60 11.32076 88.33334 -0.33 0.819 1 0042597 periplasmic space C 4 15 21 26.66667 71.42857 5 43 50 11.62791 86 -0.235 0.83 1 0055086 nucleobase, nucleoside and nucleotide metabolic process P 0 0 0 0 0 6 41 96 14.63415 42.70833 0.352 0.834 1 0033036 macromolecule localization P 0 0 0 0 0 8 68 68 11.76471 100 -0.263 0.841 1 0008104 protein localization P 0 0 0 0 0 8 68 68 11.76471 100 -0.263 0.841 1 0015031 protein transport P 6 27 27 22.22222 100 8 67 67 11.9403 100 -0.218 0.851 1 0045184 establishment of protein localization P 0 0 0 0 0 8 67 67 11.9403 100 -0.218 0.851 1 0008150 biological_process P 0 0 0 0 0 204 1603 2003 12.72614 80.02995 -0.239 0.856 1 0055114 oxidation reduction P 5 38 92 13.1579 41.30435 6 52 106 11.53846 49.0566 -0.279 0.86 1 0003723 RNA binding F 9 76 92 11.8421 82.6087 11 79 95 13.92405 83.1579 0.301 0.868 1 0006259 DNA metabolic process P 1 5 9 20 55.55556 13 95 115 13.68421 82.6087 0.26 0.871 1 0016043 cellular component organization P 0 0 0 0 0 13 96 115 13.54167 83.47826 0.219 0.889 1 0031975 envelope C 0 0 0 0 0 13 108 115 12.03704 93.91304 -0.248 0.89 1 0016491 oxidoreductase activity F 15 122 176 12.29508 69.31818 21 169 225 12.42604 75.11111 -0.158 0.891 1 0030312 external encapsulating structure C 0 0 0 0 0 13 106 115 12.26415 92.17391 -0.174 0.893 1 0005216 ion channel activity F 1 3 3 33.33333 100 1 4 4 25 100 0.73 1 1 0006547 histidine metabolic process P 0 1 5 0 20 1 4 15 25 26.66667 0.73 1 1 0008272 sulfate transport P 1 4 5 25 80 1 4 5 25 80 0.73 1 1 0004185 serine-type carboxypeptidase activity F 0 1 1 0 100 1 4 4 25 100 0.73 1 1 0055066 di-, tri-valent inorganic cation homeostasis P 0 0 0 0 0 1 4 4 25 100 0.73 1 1 0008617 guanosine metabolic process P 0 0 0 0 0 1 4 6 25 66.66666 0.73 1 1 0051052 regulation of DNA metabolic process P 0 0 0 0 0 1 4 4 25 100 0.73 1 1 0009075 histidine family amino acid metabolic process P 0 0 0 0 0 1 4 15 25 26.66667 0.73 1 1 0016841 ammonia-lyase activity F 0 0 0 0 0 1 4 6 25 66.66666 0.73 1 1 0030003 cellular cation homeostasis P 0 0 0 0 0 1 4 4 25 100 0.73 1 1 0006873 cellular ion homeostasis P 0 0 0 0 0 1 4 4 25 100 0.73 1 1 0055082 cellular chemical homeostasis P 0 0 0 0 0 1 4 4 25 100 0.73 1 1 0006413 translational initiation P 1 4 4 25 100 1 4 4 25 100 0.73 1 1 0007155 cell adhesion P 1 4 4 25 100 1 4 4 25 100 0.73 1 1 0040029 regulation of gene expression, epigenetic P 0 0 0 0 0 1 4 6 25 66.66666 0.73 1 1 0070008 serine-type exopeptidase activity F 0 0 0 0 0 1 4 4 25 100 0.73 1 1 0003743 translation initiation factor activity F 1 4 4 25 100 1 4 4 25 100 0.73 1 1 0022838 substrate specific channel activity F 0 0 0 0 0 1 4 4 25 100 0.73 1 1 0006563 L-serine metabolic process P 0 0 2 0 0 1 4 7 25 57.14286 0.73 1 1 0008484 sulfuric ester hydrolase activity F 1 4 4 25 100 1 4 4 25 100 0.73 1 1 0043231 intracellular membrane-bounded organelle C 0 0 0 0 0 1 4 7 25 57.14286 0.73 1 1 0030145 manganese ion binding F 1 4 18 25 22.22222 1 4 18 25 22.22222 0.73 1 1 0003984 acetolactate synthase activity F 1 4 4 25 100 1 4 4 25 100 0.73 1 1 0022610 biological adhesion P 0 0 0 0 0 1 4 4 25 100 0.73 1 1 0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5’-phosphomonoesters F 0 0 0 0 0 1 4 9 25 44.44444 0.73 1 1 0004721 phosphoprotein phosphatase activity F 0 1 3 0 33.33333 1 4 6 25 66.66666 0.73 1 1 0030005 cellular di-, tri-valent inorganic cation homeostasis P 0 0 0 0 0 1 4 4 25 100 0.73 1 1 0017153 sodium:dicarboxylate symporter activity F 1 5 5 20 100 1 5 5 20 100 0.481 1 1 0006071 glycerol metabolic process P 1 3 5 33.33333 60 1 5 8 20 62.5 0.481 1 1 0016868 intramolecular transferase activity, phosphotransferases F 0 3 5 0 60 1 5 9 20 55.55556 0.481 1 1 0009893 positive regulation of metabolic process P 0 0 0 0 0 1 5 5 20 100 0.481 1 1 0022803 passive transmembrane transporter activity F 0 0 0 0 0 1 5 5 20 100 0.481 1 1 0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process P 0 0 0 0 0 1 5 5 20 100 0.481 1 1 0016878 acid-thiol ligase activity F 0 0 0 0 0 1 5 7 20 71.42857 0.481 1 1 0031090 organelle membrane C 0 0 0 0 0 1 5 5 20 100 0.481 1 1 0008170 N-methyltransferase activity F 1 2 2 50 100 1 5 5 20 100 0.481 1 1 0006769 nicotinamide metabolic process P 0 0 0 0 0 1 5 13 20 38.46154 0.481 1 1 0009234 menaquinone biosynthetic process P 1 5 6 20 83.33334 1 5 6 20 83.33334 0.481 1 1 0019362 pyridine nucleotide metabolic process P 0 0 0 0 0 1 5 13 20 38.46154 0.481 1 1 0034755 transmembrane iron ion transport P 0 0 0 0 0 1 5 5 20 100 0.481 1 1 0016840 carbon-nitrogen lyase activity F 0 0 0 0 0 1 5 8 20 62.5 0.481 1 1 0022618 ribonucleoprotein complex assembly P 0 0 0 0 0 1 5 5 20 100 0.481 1 1 0016226 iron-sulfur cluster assembly P 1 5 6 20 83.33334 1 5 6 20 83.33334 0.481 1 1 0008289 lipid binding F 0 1 1 0 100 1 5 5 20 100 0.481 1 1 0015267 channel activity F 1 1 1 100 100 1 5 5 20 100 0.481 1 1 0016744 transferase activity, transferring aldehyde or ketonic groups F 0 0 0 0 0 1 5 9 20 55.55556 0.481 1 1 0031072 heat shock protein binding F 1 5 5 20 100 1 5 5 20 100 0.481 1 1 0042371 vitamin K biosynthetic process P 0 0 0 0 0 1 5 6 20 83.33334 0.481 1 1 0042362 fat-soluble vitamin biosynthetic process P 0 0 0 0 0 1 5 6 20 83.33334 0.481 1 1 0009233 menaquinone metabolic process P 0 0 0 0 0 1 5 6 20 83.33334 0.481 1 1 0042373 vitamin K metabolic process P 0 0 0 0 0 1 5 6 20 83.33334 0.481 1 1 0006775 fat-soluble vitamin metabolic process P 0 0 0 0 0 1 5 6 20 83.33334 0.481 1 1 0010604 positive regulation of macromolecule metabolic process P 0 0 0 0 0 1 5 5 20 100 0.481 1 1 0046128 purine ribonucleoside metabolic process P 0 0 0 0 0 1 5 9 20 55.55556 0.481 1 1 0031325 positive regulation of cellular metabolic process P 0 0 0 0 0 1 5 5 20 100 0.481 1 1 0048522 positive regulation of cellular process P 0 0 0 0 0 1 5 5 20 100 0.481 1 1 0048518 positive regulation of biological process P 0 0 0 0 0 1 5 5 20 100 0.481 1 1 0031163 metallo-sulfur cluster assembly P 0 0 0 0 0 1 5 6 20 83.33334 0.481 1 1 0006827 high-affinity iron ion transport P 1 5 5 20 100 1 5 5 20 100 0.481 1 1 0042278 purine nucleoside metabolic process P 0 0 2 0 0 1 5 11 20 45.45454 0.481 1 1 0009119 ribonucleoside metabolic process P 0 0 0 0 0 1 5 10 20 50 0.481 1 1 0015296 anion:cation symporter activity F 0 0 0 0 0 1 5 5 20 100 0.481 1 1 0016651 oxidoreductase activity, acting on NADH or NADPH F 0 2 2 0 100 2 12 16 16.66667 75 0.4 1 1 0044272 sulfur compound biosynthetic process P 0 0 0 0 0 2 12 25 16.66667 48 0.4 1 1 0046943 carboxylic acid transmembrane transporter activity F 0 0 0 0 0 3 20 20 15 100 0.294 1 1 0004222 metalloendopeptidase activity F 3 20 20 15 100 3 20 20 15 100 0.294 1 1 0006885 regulation of pH P 1 6 6 16.66667 100 1 6 6 16.66667 100 0.283 1 1 0043227 membrane-bounded organelle C 0 0 0 0 0 1 6 9 16.66667 66.66666 0.283 1 1 0034404 nucleobase, nucleoside and nucleotide biosynthetic process P 0 0 0 0 0 1 6 15 16.66667 40 0.283 1 1 0034654 nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process P 0 0 0 0 0 1 6 15 16.66667 40 0.283 1 1 0042242 cobyrinic acid a,c-diamide synthase activity F 1 6 7 16.66667 85.71429 1 6 7 16.66667 85.71429 0.283 1 1 0006855 multidrug transport P 1 6 6 16.66667 100 1 6 6 16.66667 100 0.283 1 1 0055067 monovalent inorganic cation homeostasis P 0 0 0 0 0 1 6 6 16.66667 100 0.283 1 1 0016877 ligase activity, forming carbon-sulfur bonds F 0 0 0 0 0 1 6 8 16.66667 75 0.283 1 1 0030976 thiamin pyrophosphate binding F 1 6 6 16.66667 100 1 6 6 16.66667 100 0.283 1 1 0015385 sodium:hydrogen antiporter activity F 1 6 6 16.66667 100 1 6 6 16.66667 100 0.283 1 1 0004359 glutaminase activity F 0 0 1 0 0 1 6 8 16.66667 75 0.283 1 1 0043566 structure-specific DNA binding F 0 0 0 0 0 1 6 7 16.66667 85.71429 0.283 1 1 0006800 oxygen and reactive oxygen species metabolic process P 1 2 2 50 100 1 6 8 16.66667 75 0.283 1 1 0015299 solute:hydrogen antiporter activity F 0 5 5 0 100 2 13 13 15.38461 100 0.278 1 1 0015300 solute:solute antiporter activity F 0 0 0 0 0 2 13 13 15.38461 100 0.278 1 1 0015298 solute:cation antiporter activity F 0 0 0 0 0 2 13 13 15.38461 100 0.278 1 1 0016791 phosphatase activity F 1 4 5 25 80 2 13 21 15.38461 61.90476 0.278 1 1 0004386 helicase activity F 4 28 28 14.28571 100 4 28 28 14.28571 100 0.235 1 1 0015297 antiporter activity F 1 10 10 10 100 3 21 21 14.28571 100 0.203 1 1 0065003 macromolecular complex assembly P 0 0 0 0 0 3 21 23 14.28571 91.30434 0.203 1 1 0022607 cellular component assembly P 0 0 0 0 0 3 21 23 14.28571 91.30434 0.203 1 1 0006790 sulfur metabolic process P 0 1 2 0 50 2 14 33 14.28571 42.42424 0.165 1 1 0008757 S-adenosylmethionine-dependent methyltransferase activity F 0 7 10 0 70 2 14 27 14.28571 51.85185 0.165 1 1 0016763 transferase activity, transferring pentosyl groups F 0 2 3 0 66.66666 1 7 20 14.28571 35 0.117 1 1 0004180 carboxypeptidase activity F 1 5 5 20 100 1 7 7 14.28571 100 0.117 1 1 0030955 potassium ion binding F 1 7 9 14.28571 77.77778 1 7 9 14.28571 77.77778 0.117 1 1 0015491 cation:cation antiporter activity F 0 0 0 0 0 1 7 7 14.28571 100 0.117 1 1 0016481 negative regulation of transcription P 1 2 3 50 66.66666 1 7 9 14.28571 77.77778 0.117 1 1 0042927 siderophore transporter activity F 0 0 0 0 0 1 7 7 14.28571 100 0.117 1 1 0010629 negative regulation of gene expression P 0 0 0 0 0 1 7 9 14.28571 77.77778 0.117 1 1 0015343 siderophore-iron transmembrane transporter activity F 1 7 7 14.28571 100 1 7 7 14.28571 100 0.117 1 1 0015891 siderophore transport P 1 7 7 14.28571 100 1 7 7 14.28571 100 0.117 1 1 0016564 transcription repressor activity F 0 6 7 0 85.71429 1 7 8 14.28571 87.5 0.117 1 1 0005451 monovalent cation:proton antiporter activity F 0 1 1 0 100 1 7 7 14.28571 100 0.117 1 1 0009451 RNA modification P 0 0 0 0 0 3 22 30 13.63636 73.33334 0.116 1 1 0033013 tetrapyrrole metabolic process P 0 0 0 0 0 2 15 24 13.33333 62.5 0.06 1 1 0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides F 0 0 0 0 0 2 15 23 13.33333 65.21739 0.06 1 1 0033014 tetrapyrrole biosynthetic process P 1 2 5 50 40 2 15 24 13.33333 62.5 0.06 1 1 0006412 translation P 8 66 103 12.12121 64.07767 9 69 106 13.04348 65.09434 0.058 1 1 0005342 organic acid transmembrane transporter activity F 0 0 0 0 0 3 23 23 13.04348 100 0.033 1 1 0000287 magnesium ion binding F 3 23 66 13.04348 34.84848 3 23 66 13.04348 34.84848 0.033 1 1 GO Gene Ontology r 0 0 0 0 0 255 1990 2413 12.81407 82.46996 0 1 1 0016772 transferase activity, transferring phosphorus-containing groups F 1 40 45 2.5 88.88889 16 125 182 12.8 68.68132 -0.005 1 1 0000910 cytokinesis P 0 0 0 0 0 1 8 8 12.5 100 -0.027 1 1 0022884 macromolecule transmembrane transporter activity F 0 0 0 0 0 1 8 8 12.5 100 -0.027 1 1 0008320 protein transmembrane transporter activity F 0 0 0 0 0 1 8 8 12.5 100 -0.027 1 1 0009236 cobalamin biosynthetic process P 1 8 11 12.5 72.72727 1 8 11 12.5 72.72727 -0.027 1 1 0065004 protein-DNA complex assembly P 0 0 0 0 0 1 8 8 12.5 100 -0.027 1 1 0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity F 1 8 8 12.5 100 1 8 8 12.5 100 -0.027 1 1 0032506 cytokinetic process P 0 0 0 0 0 1 8 8 12.5 100 -0.027 1 1 0009235 cobalamin metabolic process P 0 0 0 0 0 1 8 11 12.5 72.72727 -0.027 1 1 0006818 hydrogen transport P 0 0 0 0 0 1 8 13 12.5 61.53846 -0.027 1 1 0000917 barrier septum formation P 1 7 7 14.28571 100 1 8 8 12.5 100 -0.027 1 1 0006261 DNA-dependent DNA replication P 0 0 1 0 0 1 8 12 12.5 66.66666 -0.027 1 1 0006352 transcription initiation P 1 8 8 12.5 100 1 8 8 12.5 100 -0.027 1 1 0000270 peptidoglycan metabolic process P 0 0 0 0 0 1 8 25 12.5 32 -0.027 1 1 0006461 protein complex assembly P 0 3 3 0 100 1 8 10 12.5 80 -0.027 1 1 0015992 proton transport P 1 3 8 33.33333 37.5 1 8 13 12.5 61.53846 -0.027 1 1 0031420 alkali metal ion binding F 0 0 0 0 0 2 16 22 12.5 72.72727 -0.038 1 1 0015370 solute:sodium symporter activity F 0 0 0 0 0 2 16 16 12.5 100 -0.038 1 1 0015849 organic acid transport P 0 0 0 0 0 4 32 33 12.5 96.9697 -0.054 1 1 0046942 carboxylic acid transport P 0 0 0 0 0 4 32 33 12.5 96.9697 -0.054 1 1 0006950 response to stress P 4 19 21 21.05263 90.47619 8 64 74 12.5 86.48649 -0.076 1 1 0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds F 1 5 7 20 71.42857 3 25 44 12 56.81818 -0.123 1 1 0050662 coenzyme binding F 1 7 14 14.28571 50 8 65 94 12.30769 69.14893 -0.124 1 1 0043412 biopolymer modification P 0 0 0 0 0 10 81 100 12.34568 81 -0.129 1 1 0030313 cell envelope C 0 0 0 0 0 13 105 112 12.38095 93.75 -0.136 1 1 0044462 external encapsulating structure part C 0 0 0 0 0 13 105 112 12.38095 93.75 -0.136 1 1 0016987 sigma factor activity F 1 9 9 11.11111 100 1 9 9 11.11111 100 -0.153 1 1 0008483 transaminase activity F 1 8 15 12.5 53.33333 1 9 16 11.11111 56.25 -0.153 1 1 0016986 transcription initiation factor activity F 0 0 0 0 0 1 9 9 11.11111 100 -0.153 1 1 0009066 aspartate family amino acid metabolic process P 0 0 0 0 0 1 9 21 11.11111 42.85714 -0.153 1 1 0031402 sodium ion binding F 1 9 13 11.11111 69.23077 1 9 13 11.11111 69.23077 -0.153 1 1 0015833 peptide transport P 0 8 8 0 100 1 9 9 11.11111 100 -0.153 1 1 0006084 acetyl-CoA metabolic process P 1 2 2 50 100 1 9 12 11.11111 75 -0.153 1 1 0015171 amino acid transmembrane transporter activity F 1 5 5 20 100 1 9 9 11.11111 100 -0.153 1 1 0045229 external encapsulating structure organization P 0 0 0 0 0 2 18 34 11.11111 52.94118 -0.217 1 1 0006400 tRNA modification P 0 4 9 0 44.44444 1 10 17 10 58.82353 -0.267 1 1 0009199 ribonucleoside triphosphate metabolic process P 0 0 0 0 0 1 10 17 10 58.82353 -0.267 1 1 0005343 organic acid:sodium symporter activity F 0 0 0 0 0 1 10 10 10 100 -0.267 1 1 0003887 DNA-directed DNA polymerase activity F 1 10 13 10 76.92308 1 10 13 10 76.92308 -0.267 1 1 0015035 protein disulfide oxidoreductase activity F 1 10 11 10 90.90909 1 10 11 10 90.90909 -0.267 1 1 0019720 Mo-molybdopterin cofactor metabolic process P 0 0 0 0 0 1 10 11 10 90.90909 -0.267 1 1 0043545 molybdopterin cofactor metabolic process P 0 0 0 0 0 1 10 11 10 90.90909 -0.267 1 1 0009141 nucleoside triphosphate metabolic process P 0 0 0 0 0 1 10 18 10 55.55556 -0.267 1 1 0009144 purine nucleoside triphosphate metabolic process P 0 0 0 0 0 1 10 17 10 58.82353 -0.267 1 1 0006777 Mo-molybdopterin cofactor biosynthetic process P 1 10 11 10 90.90909 1 10 11 10 90.90909 -0.267 1 1 0032324 molybdopterin cofactor biosynthetic process P 0 2 2 0 100 1 10 11 10 90.90909 -0.267 1 1 0009205 purine ribonucleoside triphosphate metabolic process P 0 0 0 0 0 1 10 17 10 58.82353 -0.267 1 1 0005529 sugar binding F 1 10 11 10 90.90909 1 10 11 10 90.90909 -0.267 1 1 0042558 pteridine and derivative metabolic process P 0 0 0 0 0 1 11 14 9.090909 78.57143 -0.37 1 1 0042559 pteridine and derivative biosynthetic process P 0 0 0 0 0 1 11 14 9.090909 78.57143 -0.37 1 1 0034220 transmembrane ion transport P 0 0 0 0 0 1 11 16 9.090909 68.75 -0.37 1 1 0001522 pseudouridine synthesis P 1 11 13 9.090909 84.61539 1 11 13 9.090909 84.61539 -0.37 1 1 0009982 pseudouridine synthase activity F 1 11 13 9.090909 84.61539 1 11 13 9.090909 84.61539 -0.37 1 1 0042375 quinone cofactor metabolic process P 0 0 0 0 0 1 11 14 9.090909 78.57143 -0.37 1 1 0034061 DNA polymerase activity F 0 0 0 0 0 1 11 14 9.090909 78.57143 -0.37 1 1 0045426 quinone cofactor biosynthetic process P 0 0 0 0 0 1 11 14 9.090909 78.57143 -0.37 1 1 0019509 methionine salvage P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008413 8-oxo-7,8-dihydroguanine triphosphatase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0006278 RNA-dependent DNA replication P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0003964 RNA-directed DNA polymerase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008782 adenosylhomocysteine nucleosidase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0009164 nucleoside catabolic process P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0042953 lipoprotein transport P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008930 methylthioadenosine nucleosidase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0019284 methionine biosynthetic process from S-adenosylmethionine P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0051003 ligase activity, forming nitrogen-metal bonds, forming coordination complexes F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0008831 dTDP-4-dehydrorhamnose reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004795 threonine synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0009088 threonine biosynthetic process P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.383 1 1 0016289 CoA hydrolase activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0051002 ligase activity, forming nitrogen-metal bonds F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0006858 extracellular transport P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0043230 extracellular organelle C 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0031667 response to nutrient levels P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0004030 aldehyde dehydrogenase [NAD(P)+] activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0015824 proline transport P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0005298 proline:sodium symporter activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0006549 isoleucine metabolic process P 0 0 0 0 0 0 1 3 0 33.33333 -0.383 1 1 0008759 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0015746 citrate transport P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0042954 lipoprotein transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0047480 UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008766 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0015994 chlorophyll metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0051258 protein polymerization P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0015288 porin activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008379 thioredoxin peroxidase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0006282 regulation of DNA repair P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0015137 citrate transmembrane transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0016681 oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0015321 sodium-dependent phosphate transmembrane transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004467 long-chain-fatty-acid-CoA ligase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004190 aspartic-type endopeptidase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.383 1 1 0031124 mRNA 3’-end processing P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0043174 nucleoside salvage P 0 0 0 0 0 0 1 3 0 33.33333 -0.383 1 1 0008703 5-amino-6-(5-phosphoribosylamino)uracil reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008835 diaminohydroxyphosphoribosylaminopyrimidine deaminase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0016842 amidine-lyase activity F 0 0 0 0 0 0 1 2 0 50 -0.383 1 1 0008686 3,4-dihydroxy-2-butanone-4-phosphate synthase activity F 0 1 2 0 50 0 1 2 0 50 -0.383 1 1 0015037 peptide disulfide oxidoreductase activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0003935 GTP cyclohydrolase II activity F 0 1 2 0 50 0 1 2 0 50 -0.383 1 1 0016679 oxidoreductase activity, acting on diphenols and related substances as donors F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0009030 thiamin phosphate kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008962 phosphatidylglycerophosphatase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0006560 proline metabolic process P 0 0 0 0 0 0 1 3 0 33.33333 -0.383 1 1 0051748 UTP-monosaccharide-1-phosphate uridylyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0031555 transcriptional attenuation P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0018271 biotin-protein ligase activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0043101 purine salvage P 0 0 0 0 0 0 1 3 0 33.33333 -0.383 1 1 0016563 transcription activator activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0016435 rRNA (guanine) methyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0015038 glutathione disulfide oxidoreductase activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0004644 phosphoribosylglycinamide formyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0002094 polyprenyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0050790 regulation of catalytic activity P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0042594 response to starvation P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0065009 regulation of molecular function P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0031669 cellular response to nutrient levels P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0006397 mRNA processing P 0 0 1 0 0 0 1 2 0 50 -0.383 1 1 0043038 amino acid activation P 0 0 0 0 0 0 1 25 0 4 -0.383 1 1 0031123 RNA 3’-end processing P 0 0 0 0 0 0 1 2 0 50 -0.383 1 1 0006564 L-serine biosynthetic process P 0 1 2 0 50 0 1 2 0 50 -0.383 1 1 0015703 chromate transport P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0043039 tRNA aminoacylation P 0 0 2 0 0 0 1 25 0 4 -0.383 1 1 0006418 tRNA aminoacylation for protein translation P 0 0 20 0 0 0 1 25 0 4 -0.383 1 1 0043631 RNA polyadenylation P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0015109 chromate transmembrane transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0000027 ribosomal large subunit assembly and maintenance P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004647 phosphoserine phosphatase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008668 (2,3-dihydroxybenzoyl)adenylate synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008998 ribonucleoside-triphosphate reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008791 arginine N-succinyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0009376 HslUV protease complex C 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004590 orotidine-5’-phosphate decarboxylase activity F 0 1 2 0 50 0 1 2 0 50 -0.383 1 1 0006106 fumarate metabolic process P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0000101 sulfur amino acid transport P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0009061 anaerobic respiration P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0019464 glycine decarboxylation via glycine cleavage system P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0031405 lipoic acid binding F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0009001 serine O-acetyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008076 voltage-gated potassium channel complex C 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004148 dihydrolipoyl dehydrogenase activity F 0 1 2 0 50 0 1 2 0 50 -0.383 1 1 0005249 voltage-gated potassium channel activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0009750 response to fructose stimulus P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0031404 chloride ion binding F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0006821 chloride transport P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0005247 voltage-gated chloride channel activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0015079 potassium ion transmembrane transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0043865 methionine transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0004750 ribulose-phosphate 3-epimerase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0000099 sulfur amino acid transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0005980 glycogen catabolic process P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0005960 glycine cleavage complex C 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004489 methylenetetrahydrofolate reductase (NADPH) activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0006884 cell volume homeostasis P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0019478 D-amino acid catabolic process P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0045230 capsule organization P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0009399 nitrogen fixation P 0 1 2 0 50 0 1 2 0 50 -0.383 1 1 0050906 detection of stimulus involved in sensory perception P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0046961 proton-transporting ATPase activity, rotational mechanism F 0 1 5 0 20 0 1 5 0 20 -0.383 1 1 0046933 hydrogen ion transporting ATP synthase activity, rotational mechanism F 0 1 5 0 20 0 1 5 0 20 -0.383 1 1 0045261 proton-transporting ATP synthase complex, catalytic core F(1) C 0 1 5 0 20 0 1 5 0 20 -0.383 1 1 0008442 3-hydroxyisobutyrate dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0005839 proteasome core complex C 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0046352 disaccharide catabolic process P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0008974 phosphoribulokinase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0015501 glutamate:sodium symporter activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0015813 L-glutamate transport P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0019303 D-ribose catabolic process P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0016872 intramolecular lyase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0015927 trehalase activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0006511 ubiquitin-dependent protein catabolic process P 0 1 1 0 100 0 1 2 0 50 -0.383 1 1 0015169 glycerol-3-phosphate transmembrane transporter activity F 0 1 1 0 100 0 1 2 0 50 -0.383 1 1 0004298 threonine-type endopeptidase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0015794 glycerol-3-phosphate transport P 0 1 2 0 50 0 1 2 0 50 -0.383 1 1 0006573 valine metabolic process P 0 1 1 0 100 0 1 3 0 33.33333 -0.383 1 1 0004047 aminomethyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004049 anthranilate synthase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.383 1 1 0008061 chitin binding F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008783 agmatinase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0006596 polyamine biosynthetic process P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.383 1 1 0030272 5-formyltetrahydrofolate cyclo-ligase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0046037 GMP metabolic process P 0 0 0 0 0 0 1 2 0 50 -0.383 1 1 0046487 glyoxylate metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0030729 acetoacetate-CoA ligase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0017057 6-phosphogluconolactonase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0018958 phenol metabolic process P 0 0 0 0 0 0 1 2 0 50 -0.383 1 1 0005542 folic acid binding F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0006221 pyrimidine nucleotide biosynthetic process P 0 1 10 0 10 0 1 13 0 7.692307 -0.383 1 1 0005363 maltose transmembrane transporter activity F 0 1 1 0 100 0 1 2 0 50 -0.383 1 1 0016989 sigma factor antagonist activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0006528 asparagine metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0015727 lactate transport P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0015129 lactate transmembrane transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008986 pyruvate, water dikinase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004437 inositol or phosphatidylinositol phosphatase activity F 0 1 2 0 50 0 1 2 0 50 -0.383 1 1 0003908 methylated-DNA-[protein]-cysteine S-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0015439 heme-transporting ATPase activity F 0 1 2 0 50 0 1 2 0 50 -0.383 1 1 0015412 molybdate transmembrane-transporting ATPase activity F 0 1 2 0 50 0 1 2 0 50 -0.383 1 1 0031263 amine-transporting ATPase activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0017000 antibiotic biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008410 CoA-transferase activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0004564 beta-fructofuranosidase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0018454 acetoacetyl-CoA reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0009712 catechol metabolic process P 0 0 0 0 0 0 1 2 0 50 -0.383 1 1 0004143 diacylglycerol kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004383 guanylate cyclase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0006182 cGMP biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0019540 siderophore biosynthetic process from catechol P 0 0 0 0 0 0 1 2 0 50 -0.383 1 1 0004420 hydroxymethylglutaryl-CoA reductase (NADPH) activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004345 glucose-6-phosphate dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0046174 polyol catabolic process P 0 1 1 0 100 0 1 2 0 50 -0.383 1 1 0009238 enterobactin metabolic process P 0 0 0 0 0 0 1 2 0 50 -0.383 1 1 0008770 [acyl-carrier-protein] phosphodiesterase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0048502 thiamin-transporting ATPase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0015888 thiamin transport P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0019143 3-deoxy-manno-octulosonate-8-phosphatase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0003978 UDP-glucose 4-epimerase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0003841 1-acylglycerol-3-phosphate O-acyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0009347 aspartate carbamoyltransferase complex C 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0015936 coenzyme A metabolic process P 0 1 1 0 100 0 1 5 0 20 -0.383 1 1 0016851 magnesium chelatase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0016675 oxidoreductase activity, acting on heme group of donors F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0015002 heme-copper terminal oxidase activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0045277 respiratory chain complex IV C 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0005375 copper ion transmembrane transporter activity F 0 0 0 0 0 0 1 2 0 50 -0.383 1 1 0043682 copper-transporting ATPase activity F 0 0 0 0 0 0 1 2 0 50 -0.383 1 1 0003868 4-hydroxyphenylpyruvate dioxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0051205 protein insertion into membrane P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0003688 DNA replication origin binding F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004794 L-threonine ammonia-lyase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0009097 isoleucine biosynthetic process P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.383 1 1 0008694 3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0015979 photosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0033558 protein deacetylase activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0015995 chlorophyll biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008412 4-hydroxybenzoate octaprenyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0009427 flagellin-based flagellum basal body, distal rod, L ring C 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0043086 negative regulation of catalytic activity P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0006749 glutathione metabolic process P 0 1 1 0 100 0 1 3 0 33.33333 -0.383 1 1 0004362 glutathione-disulfide reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004765 shikimate kinase activity F 0 1 2 0 50 0 1 2 0 50 -0.383 1 1 0009255 Entner-Doudoroff pathway P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004456 phosphogluconate dehydratase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0044455 mitochondrial membrane part C 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0004084 branched-chain-amino-acid transaminase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0051084 ’de novo’ posttranslational protein folding P 0 0 0 0 0 0 1 2 0 50 -0.383 1 1 0005993 trehalose catabolic process P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0042257 ribosomal subunit assembly P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0042255 ribosome assembly P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0005740 mitochondrial envelope C 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0042273 ribosomal large subunit biogenesis P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0008283 cell proliferation P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0015645 fatty-acid ligase activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0005504 fatty acid binding F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0019216 regulation of lipid metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0048476 Holliday junction resolvase complex C 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0016676 oxidoreductase activity, acting on heme group of donors, oxygen as acceptor F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0033202 DNA helicase complex C 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0034979 NAD-dependent protein deacetylase activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0006458 ’de novo’ protein folding P 0 0 0 0 0 0 1 2 0 50 -0.383 1 1 0003905 alkylbase DNA N-glycosylase activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0042542 response to hydrogen peroxide P 0 0 0 0 0 0 1 2 0 50 -0.383 1 1 0000302 response to reactive oxygen species P 0 0 0 0 0 0 1 2 0 50 -0.383 1 1 0042743 hydrogen peroxide metabolic process P 0 0 0 0 0 0 1 2 0 50 -0.383 1 1 0016886 ligase activity, forming phosphoric ester bonds F 0 0 0 0 0 0 1 2 0 50 -0.383 1 1 0003909 DNA ligase activity F 0 0 0 0 0 0 1 2 0 50 -0.383 1 1 0045814 negative regulation of gene expression, epigenetic P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0016458 gene silencing P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0004407 histone deacetylase activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0004077 biotin-[acetyl-CoA-carboxylase] ligase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0070001 aspartic-type peptidase activity F 0 0 0 0 0 0 1 3 0 33.33333 -0.383 1 1 0015711 organic anion transport P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008531 riboflavin kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0009267 cellular response to starvation P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0009074 aromatic amino acid family catabolic process P 0 0 0 0 0 0 1 4 0 25 -0.383 1 1 0019439 aromatic compound catabolic process P 0 0 0 0 0 0 1 4 0 25 -0.383 1 1 0006097 glyoxylate cycle P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004451 isocitrate lyase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0006177 GMP biosynthetic process P 0 1 2 0 50 0 1 2 0 50 -0.383 1 1 0003938 IMP dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0016880 acid-ammonia (or amide) ligase activity F 0 1 1 0 100 0 1 4 0 25 -0.383 1 1 0009239 enterobactin biosynthetic process P 0 1 2 0 50 0 1 2 0 50 -0.383 1 1 0003724 RNA helicase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008897 holo-[acyl-carrier-protein] synthase activity F 0 1 2 0 50 0 1 2 0 50 -0.383 1 1 0015658 branched-chain aliphatic amino acid transmembrane transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008514 organic anion transmembrane transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008771 [citrate (pro-3S)-lyase] ligase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008814 citrate CoA-transferase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008933 lytic transglycosylase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0015821 methionine transport P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0048474 D-methionine transmembrane transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0048473 D-methionine transport P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0015424 amino acid-transporting ATPase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0015574 trehalose transmembrane transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0015771 trehalose transport P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0009366 enterobactin synthetase complex C 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008271 secondary active sulfate transmembrane transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0031564 transcription antitermination P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0003983 UTP:glucose-1-phosphate uridylyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0006011 UDP-glucose metabolic process P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0016990 arginine deiminase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0006526 arginine biosynthetic process P 0 1 11 0 9.090909 0 1 11 0 9.090909 -0.383 1 1 0006545 glycine biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004146 dihydrofolate reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004735 pyrroline-5-carboxylate reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0006561 proline biosynthetic process P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.383 1 1 0003919 FMN adenylyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0015419 sulfate transmembrane-transporting ATPase activity F 0 1 2 0 50 0 1 2 0 50 -0.383 1 1 0015803 branched-chain aliphatic amino acid transport P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0051668 localization within membrane P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0004422 hypoxanthine phosphoribosyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0006166 purine ribonucleoside salvage P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.383 1 1 0006378 mRNA polyadenylation P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004652 polynucleotide adenylyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0006424 glutamyl-tRNA aminoacylation P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.383 1 1 0003994 aconitate hydratase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008990 rRNA (guanine-N2-)-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004156 dihydropteroate synthase activity F 0 1 2 0 50 0 1 2 0 50 -0.383 1 1 0006449 regulation of translational termination P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0005739 mitochondrion C 0 0 0 0 0 0 1 3 0 33.33333 -0.383 1 1 0004150 dihydroneopterin aldolase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0015800 acidic amino acid transport P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0051603 proteolysis involved in cellular protein catabolic process P 0 0 0 0 0 0 1 2 0 50 -0.383 1 1 0000502 proteasome complex C 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0019941 modification-dependent protein catabolic process P 0 0 0 0 0 0 1 2 0 50 -0.383 1 1 0046416 D-amino acid metabolic process P 0 0 1 0 0 0 1 2 0 50 -0.383 1 1 0030384 phosphoinositide metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0032501 multicellular organismal process P 0 0 0 0 0 0 1 4 0 25 -0.383 1 1 0003008 system process P 0 0 0 0 0 0 1 3 0 33.33333 -0.383 1 1 0050877 neurological system process P 0 0 0 0 0 0 1 3 0 33.33333 -0.383 1 1 0007600 sensory perception P 0 0 0 0 0 0 1 3 0 33.33333 -0.383 1 1 0050890 cognition P 0 0 0 0 0 0 1 3 0 33.33333 -0.383 1 1 0034705 potassium channel complex C 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0019829 cation-transporting ATPase activity F 0 0 0 0 0 0 1 6 0 16.66667 -0.383 1 1 0034962 cellular biopolymer catabolic process P 0 0 0 0 0 0 1 2 0 50 -0.383 1 1 0015172 acidic amino acid transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0005313 L-glutamate transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0019323 pentose catabolic process P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0015793 glycerol transport P 0 0 0 0 0 0 1 2 0 50 -0.383 1 1 0015791 polyol transport P 0 0 0 0 0 0 1 2 0 50 -0.383 1 1 0015665 alcohol transmembrane transporter activity F 0 0 0 0 0 0 1 2 0 50 -0.383 1 1 0015166 polyol transmembrane transporter activity F 0 0 0 0 0 0 1 2 0 50 -0.383 1 1 0015168 glycerol transmembrane transporter activity F 0 0 0 0 0 0 1 2 0 50 -0.383 1 1 0022843 voltage-gated cation channel activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0031966 mitochondrial membrane C 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0051606 detection of stimulus P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0016988 transcription initiation factor antagonist activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0030613 oxidoreductase activity, acting on phosphorus or arsenic in donors F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0030611 arsenate reductase activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0003933 GTP cyclohydrolase activity F 0 0 0 0 0 0 1 4 0 25 -0.383 1 1 0019238 cyclohydrolase activity F 0 0 0 0 0 0 1 7 0 14.28571 -0.383 1 1 0019239 deaminase activity F 0 0 1 0 0 0 1 4 0 25 -0.383 1 1 0006566 threonine metabolic process P 0 0 1 0 0 0 1 4 0 25 -0.383 1 1 0046451 diaminopimelate metabolic process P 0 0 0 0 0 0 1 7 0 14.28571 -0.383 1 1 0046500 S-adenosylmethionine metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0034656 nucleobase, nucleoside and nucleotide catabolic process P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0034655 nucleobase, nucleoside, nucleotide and nucleic acid catabolic process P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0044257 cellular protein catabolic process P 0 0 0 0 0 0 1 2 0 50 -0.383 1 1 0043102 amino acid salvage P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0043632 modification-dependent macromolecule catabolic process P 0 0 0 0 0 0 1 2 0 50 -0.383 1 1 0016882 cyclo-ligase activity F 0 0 0 0 0 0 1 3 0 33.33333 -0.383 1 1 0006220 pyrimidine nucleotide metabolic process P 0 0 1 0 0 0 1 14 0 7.142857 -0.383 1 1 0016411 acylglycerol O-acyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0009085 lysine biosynthetic process P 0 0 5 0 0 0 1 7 0 14.28571 -0.383 1 1 0016749 N-succinyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0016413 O-acetyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0016412 serine O-acyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0006553 lysine metabolic process P 0 0 0 0 0 0 1 7 0 14.28571 -0.383 1 1 0006650 glycerophospholipid metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0070003 threonine-type peptidase activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0034703 cation channel complex C 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0033353 S-adenosylmethionine cycle P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0016420 malonyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0015804 neutral amino acid transport P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0015175 neutral amino acid transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0015193 L-proline transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0015142 tricarboxylic acid transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0006842 tricarboxylic acid transport P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0044421 extracellular region part C 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0050795 regulation of behavior P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0022829 wide pore channel activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0040012 regulation of locomotion P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0017006 protein-tetrapyrrole linkage P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0005267 potassium channel activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0016419 S-malonyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0005977 glycogen metabolic process P 0 0 0 0 0 0 1 5 0 20 -0.383 1 1 0015749 monosaccharide transport P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0051920 peroxiredoxin activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0008645 hexose transport P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0015145 monosaccharide transmembrane transporter activity F 0 0 0 0 0 0 1 3 0 33.33333 -0.383 1 1 0015149 hexose transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0006518 peptide metabolic process P 0 0 1 0 0 0 1 2 0 50 -0.383 1 1 0016485 protein processing P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0050486 intramolecular transferase activity, transferring hydroxy groups F 0 0 0 0 0 0 1 2 0 50 -0.383 1 1 0005743 mitochondrial inner membrane C 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0044429 mitochondrial part C 0 0 0 0 0 0 1 3 0 33.33333 -0.383 1 1 0004312 fatty-acid synthase activity F 0 0 0 0 0 0 1 4 0 25 -0.383 1 1 0042401 biogenic amine biosynthetic process P 0 0 0 0 0 0 1 9 0 11.11111 -0.383 1 1 0034702 ion channel complex C 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0031406 carboxylic acid binding F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0009746 response to hexose stimulus P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0009743 response to carbohydrate stimulus P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0034284 response to monosaccharide stimulus P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0005254 chloride channel activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0005253 anion channel activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0043168 anion binding F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0008308 voltage-gated anion channel activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0017144 drug metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0032101 regulation of response to external stimulus P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0046068 cGMP metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0009251 glucan catabolic process P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0042398 amino acid derivative biosynthetic process P 0 0 0 0 0 0 1 9 0 11.11111 -0.383 1 1 0006595 polyamine metabolic process P 0 0 0 0 0 0 1 3 0 33.33333 -0.383 1 1 0006576 biogenic amine metabolic process P 0 0 0 0 0 0 1 10 0 10 -0.383 1 1 0031300 intrinsic to organelle membrane C 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0016751 S-succinyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0004774 succinate-CoA ligase activity F 0 0 0 0 0 0 1 2 0 50 -0.383 1 1 0005385 zinc ion transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0016781 phosphotransferase activity, paired acceptors F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0008172 S-methyltransferase activity F 0 0 0 0 0 0 1 4 0 25 -0.383 1 1 0006112 energy reserve metabolic process P 0 0 0 0 0 0 1 5 0 20 -0.383 1 1 0004852 uroporphyrinogen-III synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0016999 antibiotic metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0008972 phosphomethylpyrimidine kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004411 homogentisate 1,2-dioxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0015633 zinc transporting ATPase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0015093 ferrous iron transmembrane transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0015684 ferrous iron transport P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008969 phosphohistidine phosphatase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0050920 regulation of chemotaxis P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0017003 protein-heme linkage P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0005971 ribonucleoside-diphosphate reductase complex C 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004314 [acyl-carrier-protein] S-malonyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008987 quinolinate synthetase A activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0015758 glucose transport P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0005355 glucose transmembrane transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0003874 6-pyruvoyltetrahydropterin synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0006729 tetrahydrobiopterin biosynthetic process P 0 1 2 0 50 0 1 2 0 50 -0.383 1 1 0004333 fumarate hydratase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0006465 signal peptide processing P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0006505 GPI anchor metabolic process P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004448 isocitrate dehydrogenase activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0008818 cobalamin 5’-phosphate synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0031227 intrinsic to endoplasmic reticulum membrane C 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004614 phosphoglucomutase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004108 citrate (Si)-synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008444 CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0000104 succinate dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0043815 phosphoribosylglycinamide formyltransferase 2 activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0006829 zinc ion transport P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008113 peptide-methionine-(S)-S-oxide reductase activity F 0 1 4 0 25 0 1 4 0 25 -0.383 1 1 0004008 copper-exporting ATPase activity F 0 1 2 0 50 0 1 2 0 50 -0.383 1 1 0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004149 dihydrolipoyllysine-residue succinyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0043752 adenosylcobinamide kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0043753 adenosylcobinamide-phosphate guanylyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0016671 oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor F 0 0 2 0 0 0 1 5 0 20 -0.383 1 1 0045252 oxoglutarate dehydrogenase complex C 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004775 succinate-CoA ligase (ADP-forming) activity F 0 1 2 0 50 0 1 2 0 50 -0.383 1 1 0008852 exodeoxyribonuclease I activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0006869 lipid transport P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0006559 L-phenylalanine catabolic process P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.383 1 1 0000286 alanine dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008108 UDP-glucose:hexose-1-phosphate uridylyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008988 rRNA (adenine-N6-)-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008097 5S rRNA binding F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0000062 acyl-CoA binding F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004121 cystathionine beta-lyase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0051726 regulation of cell cycle P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0030420 establishment of competence for transformation P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004096 catalase activity F 0 1 2 0 50 0 1 2 0 50 -0.383 1 1 0008725 DNA-3-methyladenine glycosylase I activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0051085 chaperone cofactor-dependent protein folding P 0 1 2 0 50 0 1 2 0 50 -0.383 1 1 0005319 lipid transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008448 N-acetylglucosamine-6-phosphate deacetylase activity F 0 1 2 0 50 0 1 2 0 50 -0.383 1 1 0009379 Holliday junction helicase complex C 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008788 alpha,alpha-phosphotrehalase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004789 thiamin-phosphate diphosphorylase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0019217 regulation of fatty acid metabolic process P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008683 2-oxoglutarate decarboxylase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0006825 copper ion transport P 0 1 2 0 50 0 1 2 0 50 -0.383 1 1 0008864 formyltetrahydrofolate deformylase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004129 cytochrome-c oxidase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0045278 plasma membrane respiratory chain complex IV C 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0016847 1-aminocyclopropane-1-carboxylate synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008909 isochorismate synthase activity F 0 1 2 0 50 0 1 2 0 50 -0.383 1 1 0017169 CDP-alcohol phosphatidyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0004034 aldose 1-epimerase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0017136 NAD-dependent histone deacetylase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0009186 deoxyribonucleoside diphosphate metabolic process P 0 1 1 0 100 0 1 2 0 50 -0.383 1 1 0006476 protein amino acid deacetylation P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0070204 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008756 o-succinylbenzoate-CoA ligase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0005744 mitochondrial inner membrane presequence translocase complex C 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0042127 regulation of cell proliferation P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0003910 DNA ligase (ATP) activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0042744 hydrogen peroxide catabolic process P 0 1 2 0 50 0 1 2 0 50 -0.383 1 1 0006342 chromatin silencing P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0009262 deoxyribonucleotide metabolic process P 0 0 0 0 0 0 1 5 0 20 -0.383 1 1 0008430 selenium binding F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004066 asparagine synthase (glutamine-hydrolyzing) activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0006529 asparagine biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0046146 tetrahydrobiopterin metabolic process P 0 0 0 0 0 0 1 2 0 50 -0.383 1 1 0009132 nucleoside diphosphate metabolic process P 0 0 0 0 0 0 1 2 0 50 -0.383 1 1 0009403 toxin biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008825 cyclopropane-fatty-acyl-phospholipid synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004044 amidophosphoribosyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004018 adenylosuccinate lyase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004015 adenosylmethionine-8-amino-7-oxononanoate transaminase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004326 tetrahydrofolylpolyglutamate synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008138 protein tyrosine/serine/threonine phosphatase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0006637 acyl-CoA metabolic process P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0003906 DNA-(apurinic or apyrimidinic site) lyase activity F 0 1 2 0 50 0 1 2 0 50 -0.383 1 1 0004040 amidase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0003878 ATP citrate synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0016291 acyl-CoA thioesterase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008121 ubiquinol-cytochrome-c reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0030614 oxidoreductase activity, acting on phosphorus or arsenic in donors, with disulfide as acceptor F 0 0 0 0 0 0 1 1 0 100 -0.383 1 1 0019008 molybdopterin synthase complex C 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008710 8-amino-7-oxononanoate synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0004450 isocitrate dehydrogenase (NADP+) activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0009014 succinyl-diaminopimelate desuccinylase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0009431 flagellin-based flagellum basal body, MS ring C 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0015159 polysaccharide transmembrane transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0006047 UDP-N-acetylglucosamine metabolic process P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0009089 lysine biosynthetic process via diaminopimelate P 0 1 5 0 20 0 1 7 0 14.28571 -0.383 1 1 0015774 polysaccharide transport P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0030254 protein secretion by the type III secretion system P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008761 UDP-N-acetylglucosamine 2-epimerase activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0009382 imidazoleglycerol-phosphate synthase complex C 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0008794 arsenate reductase (glutaredoxin) activity F 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0050897 cobalt ion binding F 0 1 5 0 20 0 1 5 0 20 -0.383 1 1 0009428 flagellin-based flagellum basal body, distal rod, P ring C 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0030257 type III protein secretion system complex C 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0045227 capsule polysaccharide biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.383 1 1 0042618 poly-hydroxybutyrate metabolic process P 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0006081 cellular aldehyde metabolic process P 0 1 1 0 100 0 2 4 0 50 -0.542 1 1 0045226 extracellular polysaccharide biosynthetic process P 0 1 1 0 100 0 2 2 0 100 -0.542 1 1 0044423 virion part C 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0044242 cellular lipid catabolic process P 0 0 0 0 0 0 2 4 0 50 -0.542 1 1 0019012 virion C 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0009037 tyrosine-based site-specific recombinase activity F 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0043225 anion transmembrane-transporting ATPase activity F 0 0 0 0 0 0 2 6 0 33.33333 -0.542 1 1 0046358 butyrate biosynthetic process P 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0015151 alpha-glucoside transmembrane transporter activity F 0 0 0 0 0 0 2 3 0 66.66666 -0.542 1 1 0016790 thiolester hydrolase activity F 0 1 1 0 100 0 2 3 0 66.66666 -0.542 1 1 0001871 pattern binding F 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0016405 CoA-ligase activity F 0 0 0 0 0 0 2 4 0 50 -0.542 1 1 0008079 translation termination factor activity F 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0015929 hexosaminidase activity F 0 0 0 0 0 0 2 3 0 66.66666 -0.542 1 1 0034440 lipid oxidation P 0 0 0 0 0 0 2 3 0 66.66666 -0.542 1 1 0030258 lipid modification P 0 0 0 0 0 0 2 4 0 50 -0.542 1 1 0019748 secondary metabolic process P 0 0 0 0 0 0 2 9 0 22.22222 -0.542 1 1 0015179 L-amino acid transmembrane transporter activity F 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor F 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0000918 selection of site for barrier septum formation P 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0019395 fatty acid oxidation P 0 0 0 0 0 0 2 3 0 66.66666 -0.542 1 1 0009062 fatty acid catabolic process P 0 0 1 0 0 0 2 4 0 50 -0.542 1 1 0009378 four-way junction helicase activity F 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0042947 glucoside transmembrane transporter activity F 0 0 0 0 0 0 2 3 0 66.66666 -0.542 1 1 0015768 maltose transport P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.542 1 1 0015154 disaccharide transmembrane transporter activity F 0 0 0 0 0 0 2 3 0 66.66666 -0.542 1 1 0008213 protein amino acid alkylation P 0 0 0 0 0 0 2 3 0 66.66666 -0.542 1 1 0006635 fatty acid beta-oxidation P 0 0 1 0 0 0 2 3 0 66.66666 -0.542 1 1 0009636 response to toxin P 0 0 1 0 0 0 2 3 0 66.66666 -0.542 1 1 0006575 amino acid derivative metabolic process P 0 0 0 0 0 0 2 11 0 18.18182 -0.542 1 1 0051790 short-chain fatty acid biosynthetic process P 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0046058 cAMP metabolic process P 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0016755 transferase activity, transferring amino-acyl groups F 0 0 1 0 0 0 2 4 0 50 -0.542 1 1 0006189 ’de novo’ IMP biosynthetic process P 0 2 6 0 33.33333 0 2 6 0 33.33333 -0.542 1 1 0008276 protein methyltransferase activity F 0 2 3 0 66.66666 0 2 4 0 50 -0.542 1 1 0019836 hemolysis by symbiont of host red blood cells P 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0009338 exodeoxyribonuclease V complex C 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0051715 cytolysis of cells of another organism P 0 1 1 0 100 0 2 2 0 100 -0.542 1 1 0043094 cellular metabolic compound salvage P 0 0 1 0 0 0 2 7 0 28.57143 -0.542 1 1 0016881 acid-amino acid ligase activity F 0 0 1 0 0 0 2 11 0 18.18182 -0.542 1 1 0009009 site-specific recombinase activity F 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0008907 integrase activity F 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor F 0 0 0 0 0 0 2 4 0 50 -0.542 1 1 0009435 NAD biosynthetic process P 0 2 6 0 33.33333 0 2 6 0 33.33333 -0.542 1 1 0006479 protein amino acid methylation P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.542 1 1 0003995 acyl-CoA dehydrogenase activity F 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase P 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0034062 RNA polymerase activity F 0 0 0 0 0 0 2 6 0 33.33333 -0.542 1 1 0015081 sodium ion transmembrane transporter activity F 0 2 4 0 50 0 2 4 0 50 -0.542 1 1 0016748 succinyltransferase activity F 0 0 0 0 0 0 2 3 0 66.66666 -0.542 1 1 0009065 glutamine family amino acid catabolic process P 0 0 0 0 0 0 2 5 0 40 -0.542 1 1 0016668 oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor F 0 0 0 0 0 0 2 7 0 28.57143 -0.542 1 1 0008374 O-acyltransferase activity F 0 0 0 0 0 0 2 5 0 40 -0.542 1 1 0003715 transcription termination factor activity F 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0004605 phosphatidate cytidylyltransferase activity F 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0019674 NAD metabolic process P 0 0 0 0 0 0 2 6 0 33.33333 -0.542 1 1 0015930 glutamate synthase activity F 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0046459 short-chain fatty acid metabolic process P 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0019200 carbohydrate kinase activity F 0 0 0 0 0 0 2 6 0 33.33333 -0.542 1 1 0046395 carboxylic acid catabolic process P 0 0 0 0 0 0 2 4 0 50 -0.542 1 1 0016054 organic acid catabolic process P 0 0 0 0 0 0 2 4 0 50 -0.542 1 1 0005244 voltage-gated ion channel activity F 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0016778 diphosphotransferase activity F 0 0 0 0 0 0 2 3 0 66.66666 -0.542 1 1 0016776 phosphotransferase activity, phosphate group as acceptor F 0 0 1 0 0 0 2 8 0 25 -0.542 1 1 0022832 voltage-gated channel activity F 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0032508 DNA duplex unwinding P 0 0 0 0 0 0 2 4 0 50 -0.542 1 1 0032392 DNA geometric change P 0 0 0 0 0 0 2 4 0 50 -0.542 1 1 0004812 aminoacyl-tRNA ligase activity F 0 2 26 0 7.692307 0 2 26 0 7.692307 -0.542 1 1 0022836 gated channel activity F 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0019605 butyrate metabolic process P 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0016149 translation release factor activity, codon specific F 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0008175 tRNA methyltransferase activity F 0 0 1 0 0 0 2 6 0 33.33333 -0.542 1 1 0016875 ligase activity, forming carbon-oxygen bonds F 0 0 0 0 0 0 2 26 0 7.692307 -0.542 1 1 0016838 carbon-oxygen lyase activity, acting on phosphates F 0 0 1 0 0 0 2 5 0 40 -0.542 1 1 0003747 translation release factor activity F 0 1 1 0 100 0 2 2 0 100 -0.542 1 1 0030247 polysaccharide binding F 0 1 1 0 100 0 2 2 0 100 -0.542 1 1 0009071 serine family amino acid catabolic process P 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0006206 pyrimidine base metabolic process P 0 0 1 0 0 0 2 10 0 20 -0.542 1 1 0019856 pyrimidine base biosynthetic process P 0 0 1 0 0 0 2 7 0 28.57143 -0.542 1 1 0004563 beta-N-acetylhexosaminidase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.542 1 1 0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines F 0 0 0 0 0 0 2 10 0 20 -0.542 1 1 0009331 glycerol-3-phosphate dehydrogenase complex C 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.542 1 1 0003941 L-serine ammonia-lyase activity F 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0006366 transcription from RNA polymerase II promoter P 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0042619 poly-hydroxybutyrate biosynthetic process P 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0006268 DNA unwinding during replication P 0 2 4 0 50 0 2 4 0 50 -0.542 1 1 0009113 purine base biosynthetic process P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.542 1 1 0005261 cation channel activity F 0 1 1 0 100 0 2 2 0 100 -0.542 1 1 0009294 DNA mediated transformation P 0 1 1 0 100 0 2 2 0 100 -0.542 1 1 0006354 RNA elongation P 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0004748 ribonucleoside-diphosphate reductase activity F 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0032786 positive regulation of RNA elongation P 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0015098 molybdate ion transmembrane transporter activity F 0 1 2 0 50 0 2 3 0 66.66666 -0.542 1 1 0009404 toxin metabolic process P 0 1 1 0 100 0 2 2 0 100 -0.542 1 1 0015689 molybdate ion transport P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.542 1 1 0009292 genetic transfer P 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0006144 purine base metabolic process P 0 0 0 0 0 0 2 4 0 50 -0.542 1 1 0003899 DNA-directed RNA polymerase activity F 0 2 6 0 33.33333 0 2 6 0 33.33333 -0.542 1 1 0030256 type I protein secretion system complex C 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0030253 protein secretion by the type I secretion system P 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0034243 regulation of RNA elongation from RNA polymerase II promoter P 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0015662 ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism F 0 2 3 0 66.66666 0 2 4 0 50 -0.542 1 1 0015420 cobalamin-transporting ATPase activity F 0 2 4 0 50 0 2 4 0 50 -0.542 1 1 0000150 recombinase activity F 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0019363 pyridine nucleotide biosynthetic process P 0 2 4 0 50 0 2 6 0 33.33333 -0.542 1 1 0006527 arginine catabolic process P 0 2 4 0 50 0 2 5 0 40 -0.542 1 1 0009250 glucan biosynthetic process P 0 2 3 0 66.66666 0 2 6 0 33.33333 -0.542 1 1 0004806 triacylglycerol lipase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.542 1 1 0006662 glycerol ether metabolic process P 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0004368 glycerol-3-phosphate dehydrogenase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.542 1 1 0032784 regulation of RNA elongation P 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0019028 viral capsid C 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0031119 tRNA pseudouridine synthesis P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.542 1 1 0006357 regulation of transcription from RNA polymerase II promoter P 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0015563 uptake transmembrane transporter activity F 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0003848 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity F 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0004076 biotin synthase activity F 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0016876 ligase activity, forming aminoacyl-tRNA and related compounds F 0 1 3 0 33.33333 0 2 26 0 7.692307 -0.542 1 1 0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor F 0 1 1 0 100 0 2 7 0 28.57143 -0.542 1 1 0006546 glycine catabolic process P 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0004412 homoserine dehydrogenase activity F 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0015969 guanosine tetraphosphate metabolic process P 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0006207 ’de novo’ pyrimidine base biosynthetic process P 0 2 6 0 33.33333 0 2 6 0 33.33333 -0.542 1 1 0009225 nucleotide-sugar metabolic process P 0 0 0 0 0 0 2 5 0 40 -0.542 1 1 0032968 positive regulation of RNA elongation from RNA polymerase II promoter P 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0008965 phosphoenolpyruvate-protein phosphotransferase activity F 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0006979 response to oxidative stress P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.542 1 1 0031554 regulation of transcription termination P 0 1 1 0 100 0 2 2 0 100 -0.542 1 1 0016300 tRNA (uracil) methyltransferase activity F 0 2 2 0 100 0 2 3 0 66.66666 -0.542 1 1 0006072 glycerol-3-phosphate metabolic process P 0 2 4 0 50 0 2 4 0 50 -0.542 1 1 0004747 ribokinase activity F 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0004659 prenyltransferase activity F 0 2 2 0 100 0 2 3 0 66.66666 -0.542 1 1 0009381 excinuclease ABC activity F 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0009380 excinuclease repair complex C 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0030983 mismatched DNA binding F 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0006289 nucleotide-excision repair P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.542 1 1 0008428 ribonuclease inhibitor activity F 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0008967 phosphoglycolate phosphatase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.542 1 1 0000107 imidazoleglycerol-phosphate synthase activity F 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0043190 ATP-binding cassette (ABC) transporter complex C 0 2 8 0 25 0 2 8 0 25 -0.542 1 1 0016433 rRNA (adenine) methyltransferase activity F 0 1 1 0 100 0 2 2 0 100 -0.542 1 1 0004109 coproporphyrinogen oxidase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.542 1 1 0003840 gamma-glutamyltransferase activity F 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0006368 RNA elongation from RNA polymerase II promoter P 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0051883 killing of cells in other organism during symbiotic interaction P 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0051701 interaction with host P 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0018298 protein-chromophore linkage P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.542 1 1 0048583 regulation of response to stimulus P 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0051817 modification of morphology or physiology of other organism during symbiotic interaction P 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0001906 cell killing P 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0001897 cytolysis by symbiont of host cells P 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0051801 cytolysis of cells in other organism during symbiotic interaction P 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0015128 gluconate transmembrane transporter activity F 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0052331 hemolysis by organism of red blood cells in other organism during symbiotic interaction P 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0044003 modification by symbiont of host morphology or physiology P 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0046379 extracellular polysaccharide metabolic process P 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0015725 gluconate transport P 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0030151 molybdenum ion binding F 0 2 5 0 40 0 2 5 0 40 -0.542 1 1 0031640 killing of cells of another organism P 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0009326 formate dehydrogenase complex C 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0008863 formate dehydrogenase activity F 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0004181 metallocarboxypeptidase activity F 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0004016 adenylate cyclase activity F 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0006171 cAMP biosynthetic process P 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0016846 carbon-sulfur lyase activity F 0 0 0 0 0 0 2 4 0 50 -0.542 1 1 0004474 malate synthase activity F 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0001907 killing by symbiont of host cells P 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0052111 modification by symbiont of host structure P 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0052043 modification by symbiont of host cellular component P 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0052025 modification by symbiont of host cell membrane P 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0052188 modification of cellular component in other organism during symbiotic interaction P 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0052185 modification of structure of other organism during symbiotic interaction P 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0051818 disruption of cells of other organism during symbiotic interaction P 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0008745 N-acetylmuramoyl-L-alanine amidase activity F 0 2 2 0 100 0 2 2 0 100 -0.542 1 1 0052332 modification by organism of cell membrane in other organism during symbiotic interaction P 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0044004 disruption by symbiont of host cells P 0 0 0 0 0 0 2 2 0 100 -0.542 1 1 0006801 superoxide metabolic process P 0 3 3 0 100 0 3 4 0 75 -0.664 1 1 0016742 hydroxymethyl-, formyl- and related transferase activity F 0 3 4 0 75 0 3 6 0 50 -0.664 1 1 0055072 iron ion homeostasis P 0 0 0 0 0 0 3 3 0 100 -0.664 1 1 0004784 superoxide dismutase activity F 0 3 3 0 100 0 3 3 0 100 -0.664 1 1 0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines F 0 3 4 0 75 0 3 4 0 75 -0.664 1 1 0015116 sulfate transmembrane transporter activity F 0 2 2 0 100 0 3 4 0 75 -0.664 1 1 0003918 DNA topoisomerase (ATP-hydrolyzing) activity F 0 3 5 0 60 0 3 5 0 60 -0.664 1 1 0009086 methionine biosynthetic process P 0 3 8 0 37.5 0 3 8 0 37.5 -0.664 1 1 0006555 methionine metabolic process P 0 2 2 0 100 0 3 8 0 37.5 -0.664 1 1 0006188 IMP biosynthetic process P 0 1 2 0 50 0 3 8 0 37.5 -0.664 1 1 0019213 deacetylase activity F 0 0 0 0 0 0 3 5 0 60 -0.664 1 1 0006094 gluconeogenesis P 0 3 6 0 50 0 3 6 0 50 -0.664 1 1 0051171 regulation of nitrogen compound metabolic process P 0 0 0 0 0 0 3 3 0 100 -0.664 1 1 0019740 nitrogen utilization P 0 0 0 0 0 0 3 3 0 100 -0.664 1 1 0006073 glucan metabolic process P 0 0 0 0 0 0 3 7 0 42.85714 -0.664 1 1 0009426 flagellin-based flagellum basal body, distal rod C 0 1 1 0 100 0 3 3 0 100 -0.664 1 1 0016684 oxidoreductase activity, acting on peroxide as acceptor F 0 0 0 0 0 0 3 4 0 75 -0.664 1 1 0006415 translational termination P 0 3 3 0 100 0 3 3 0 100 -0.664 1 1 0019866 organelle inner membrane C 0 2 2 0 100 0 3 3 0 100 -0.664 1 1 0019290 siderophore biosynthetic process P 0 3 3 0 100 0 3 4 0 75 -0.664 1 1 0015766 disaccharide transport P 0 0 0 0 0 0 3 4 0 75 -0.664 1 1 0006808 regulation of nitrogen utilization P 0 3 3 0 100 0 3 3 0 100 -0.664 1 1 0008137 NADH dehydrogenase (ubiquinone) activity F 0 3 3 0 100 0 3 3 0 100 -0.664 1 1 0003690 double-stranded DNA binding F 0 1 1 0 100 0 3 3 0 100 -0.664 1 1 0009424 flagellin-based flagellum hook C 0 3 3 0 100 0 3 3 0 100 -0.664 1 1 0033177 proton-transporting two-sector ATPase complex, proton-transporting domain C 0 1 1 0 100 0 3 4 0 75 -0.664 1 1 0045263 proton-transporting ATP synthase complex, coupling factor F(o) C 0 3 4 0 75 0 3 4 0 75 -0.664 1 1 0004372 glycine hydroxymethyltransferase activity F 0 0 2 0 0 0 3 8 0 37.5 -0.664 1 1 0005326 neurotransmitter transporter activity F 0 0 0 0 0 0 3 3 0 100 -0.664 1 1 0042726 riboflavin and derivative metabolic process P 0 0 0 0 0 0 3 6 0 50 -0.664 1 1 0009253 peptidoglycan catabolic process P 0 3 3 0 100 0 3 3 0 100 -0.664 1 1 0016042 lipid catabolic process P 0 1 6 0 16.66667 0 3 8 0 37.5 -0.664 1 1 0004803 transposase activity F 0 3 5 0 60 0 3 5 0 60 -0.664 1 1 0008409 5’-3’ exonuclease activity F 0 3 3 0 100 0 3 3 0 100 -0.664 1 1 0042727 riboflavin and derivative biosynthetic process P 0 0 0 0 0 0 3 6 0 50 -0.664 1 1 0046040 IMP metabolic process P 0 0 0 0 0 0 3 8 0 37.5 -0.664 1 1 0042946 glucoside transport P 0 0 0 0 0 0 3 4 0 75 -0.664 1 1 0042575 DNA polymerase complex C 0 0 0 0 0 0 3 3 0 100 -0.664 1 1 0017150 tRNA dihydrouridine synthase activity F 0 3 3 0 100 0 3 3 0 100 -0.664 1 1 0002098 tRNA wobble uridine modification P 0 3 3 0 100 0 3 3 0 100 -0.664 1 1 0006298 mismatch repair P 0 3 3 0 100 0 3 3 0 100 -0.664 1 1 0006771 riboflavin metabolic process P 0 0 0 0 0 0 3 6 0 50 -0.664 1 1 0009360 DNA polymerase III complex C 0 3 3 0 100 0 3 3 0 100 -0.664 1 1 0008658 penicillin binding F 0 3 4 0 75 0 3 4 0 75 -0.664 1 1 0008854 exodeoxyribonuclease V activity F 0 3 3 0 100 0 3 3 0 100 -0.664 1 1 0006541 glutamine metabolic process P 0 3 10 0 30 0 3 11 0 27.27273 -0.664 1 1 0000017 alpha-glucoside transport P 0 0 0 0 0 0 3 4 0 75 -0.664 1 1 0003954 NADH dehydrogenase activity F 0 0 0 0 0 0 3 3 0 100 -0.664 1 1 0050136 NADH dehydrogenase (quinone) activity F 0 0 0 0 0 0 3 3 0 100 -0.664 1 1 0008535 respiratory chain complex IV assembly P 0 3 3 0 100 0 3 3 0 100 -0.664 1 1 0042440 pigment metabolic process P 0 0 0 0 0 0 3 5 0 60 -0.664 1 1 0016888 endodeoxyribonuclease activity, producing 5’-phosphomonoesters F 0 3 3 0 100 0 3 4 0 75 -0.664 1 1 0009237 siderophore metabolic process P 0 0 0 0 0 0 3 4 0 75 -0.664 1 1 0033178 proton-transporting two-sector ATPase complex, catalytic domain C 0 2 4 0 50 0 3 7 0 42.85714 -0.664 1 1 0006544 glycine metabolic process P 0 0 2 0 0 0 3 5 0 60 -0.664 1 1 0006836 neurotransmitter transport P 0 3 3 0 100 0 3 3 0 100 -0.664 1 1 0009187 cyclic nucleotide metabolic process P 0 0 0 0 0 0 3 3 0 100 -0.664 1 1 0016728 oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor F 0 0 0 0 0 0 3 4 0 75 -0.664 1 1 0016725 oxidoreductase activity, acting on CH or CH2 groups F 0 0 0 0 0 0 3 5 0 60 -0.664 1 1 0009190 cyclic nucleotide biosynthetic process P 0 0 0 0 0 0 3 3 0 100 -0.664 1 1 0006012 galactose metabolic process P 0 3 4 0 75 0 3 4 0 75 -0.664 1 1 0016849 phosphorus-oxygen lyase activity F 0 0 0 0 0 0 3 4 0 75 -0.664 1 1 0009975 cyclase activity F 0 0 0 0 0 0 3 3 0 100 -0.664 1 1 0003913 DNA photolyase activity F 0 3 4 0 75 0 3 4 0 75 -0.664 1 1 0004601 peroxidase activity F 0 3 4 0 75 0 3 4 0 75 -0.664 1 1 0046148 pigment biosynthetic process P 0 0 0 0 0 0 3 5 0 60 -0.664 1 1 0009297 pilus formation P 0 3 3 0 100 0 3 3 0 100 -0.664 1 1 0019321 pentose metabolic process P 0 0 0 0 0 0 3 4 0 75 -0.664 1 1 0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen F 0 3 3 0 100 0 3 3 0 100 -0.664 1 1 0046364 monosaccharide biosynthetic process P 0 0 0 0 0 0 3 6 0 50 -0.664 1 1 0045005 maintenance of fidelity during DNA-dependent DNA replication P 0 0 0 0 0 0 3 3 0 100 -0.664 1 1 0019319 hexose biosynthetic process P 0 0 0 0 0 0 3 6 0 50 -0.664 1 1 0008199 ferric iron binding F 0 3 3 0 100 0 3 3 0 100 -0.664 1 1 0043711 pilus organization P 0 0 0 0 0 0 3 3 0 100 -0.664 1 1 0008144 drug binding F 0 0 0 0 0 0 3 4 0 75 -0.664 1 1 0006879 cellular iron ion homeostasis P 0 3 3 0 100 0 3 3 0 100 -0.664 1 1 0016783 sulfurtransferase activity F 0 1 4 0 25 0 3 9 0 33.33333 -0.664 1 1 0006090 pyruvate metabolic process P 0 0 0 0 0 0 3 8 0 37.5 -0.664 1 1 0015889 cobalamin transport P 0 3 4 0 75 0 3 4 0 75 -0.664 1 1 0046165 alcohol biosynthetic process P 0 0 0 0 0 0 3 7 0 42.85714 -0.664 1 1 0005328 neurotransmitter:sodium symporter activity F 0 3 3 0 100 0 3 3 0 100 -0.664 1 1 0031967 organelle envelope C 0 0 0 0 0 0 3 3 0 100 -0.664 1 1 0006014 D-ribose metabolic process P 0 2 2 0 100 0 3 3 0 100 -0.664 1 1 0008028 monocarboxylic acid transmembrane transporter activity F 0 0 0 0 0 0 3 3 0 100 -0.664 1 1 0043244 regulation of protein complex disassembly P 0 0 0 0 0 0 3 3 0 100 -0.664 1 1 0015718 monocarboxylic acid transport P 0 0 0 0 0 0 3 3 0 100 -0.664 1 1 0016645 oxidoreductase activity, acting on the CH-NH group of donors F 0 0 0 0 0 0 3 5 0 60 -0.664 1 1 0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor F 0 0 0 0 0 0 3 5 0 60 -0.664 1 1 0016721 oxidoreductase activity, acting on superoxide radicals as acceptor F 0 0 0 0 0 0 3 3 0 100 -0.664 1 1 0009231 riboflavin biosynthetic process P 0 3 6 0 50 0 3 6 0 50 -0.664 1 1 0004857 enzyme inhibitor activity F 0 1 1 0 100 0 3 3 0 100 -0.664 1 1 0006525 arginine metabolic process P 0 2 5 0 40 0 3 16 0 18.75 -0.664 1 1 0009252 peptidoglycan biosynthetic process P 0 3 19 0 15.78947 0 3 19 0 15.78947 -0.664 1 1