https://xmlpipedb.lmucs.io/biodb/fall2013/index.php?action=history&feed=atom&title=Kmeilak_Week_8 2026-07-03T15:25:19Z Revision history for this page on the wiki MediaWiki 1.20.3 https://xmlpipedb.lmucs.io/biodb/fall2013/index.php?title=Kmeilak_Week_8&diff=3742&oldid=prev 2013-10-18T20:20:00Z

<p></p> <table class='diff diff-contentalign-left'> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr style='vertical-align: top;'> <td colspan='2' style="background-color: white; color:black;">← Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 20:20, 18 October 2013</td> </tr><tr><td colspan="2" class="diff-lineno">Line 145:</td> <td colspan="2" class="diff-lineno">Line 145:</td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>===Final Paragraph===</div></td><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>===Final Paragraph===</div></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>−</td><td style="background: #ffa; color:black; font-size: smaller;"><div>&#160;</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">Due to the vast number of genes for many of these processes, it is impossible to accurately say exactly what distinguishes the pathogenic strain of V. cholerae from the non-pathogenic strain in most cases. However, it is known from looking at the decreased expression of the 3&#039;-5&#039; exonuclease activity and of the polyribonucleotide nucleotidyltransferase activity genes that the pathogenic strain has significantly decreased 3&#039;-5&#039; exonuclease activity and decreased mRNA degradation. The decreased mRNA degradation and proofreading in the post-transcriptional stages most likely increases the number of mutations seen in the pathogenic strain, which along with an increased rate of translation from the decreased mRNA degradation can significantly change the biochemical nature of the bacteria and its processes. This alone may be enough to confer the pathogenic nature of V. cholerae seen in the patient.</ins></div></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> </table>

Kmeilak https://xmlpipedb.lmucs.io/biodb/fall2013/index.php?title=Kmeilak_Week_8&diff=3741&oldid=prev 2013-10-18T20:14:32Z

<p></p> <table class='diff diff-contentalign-left'> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr style='vertical-align: top;'> <td colspan='2' style="background-color: white; color:black;">← Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 20:14, 18 October 2013</td> </tr><tr><td colspan="2" class="diff-lineno">Line 86:</td> <td colspan="2" class="diff-lineno">Line 86:</td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>*Clicked on polyribonucleotide nucleotidyltransferase activity which opened GenMAPP</div></td><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>*Clicked on polyribonucleotide nucleotidyltransferase activity which opened GenMAPP</div></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>*polyribonucleotide nucleotidyltransferase activity gene decreased expression</div></td><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>*polyribonucleotide nucleotidyltransferase activity gene decreased expression</div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">*polyribonucleotide nucleotidyltransferase activity &quot;Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3&#039;- to 5&#039;-direction&quot; (GenMAPP)</ins></div></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>*Did a gene id search for VC0468, found nothing</div></td><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>*Did a gene id search for VC0468, found nothing</div></td></tr> <tr><td colspan="2" class="diff-lineno">Line 96:</td> <td colspan="2" class="diff-lineno">Line 97:</td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>*transporter activity</div></td><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"><div>*transporter activity</div></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">*Clicked on transport, which opened GenMAPP</ins></div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">*mix of increased and decreased genes</ins></div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">*Clicked on outer-membrane bound periplasmic space, which opened GenMAPP</ins></div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">*mix of increased and decresed genes, more increased than decreased</ins></div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">*Clicked on transporter activity, which opened GenMAPP</ins></div></td></tr> <tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">*mix of increased and decresed genes, more increased than decreased</ins></div></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'>&#160;</td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> </table>

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Stack trace:
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#4 /apps/xmlpipedb/biodb/fall2013/includes/diff/DifferenceEngine.php(763): Diff->__construct()
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