Difference between revisions of "Lena Week 5"
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[[Image:Lena1.PNG]] | [[Image:Lena1.PNG]] | ||
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| − | *'''This is what the entry showed. | + | *'''This is what the entry showed. It it the main page containing general information about EGFR.''' |
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[[Image:Lena2.PNG]] | [[Image:Lena2.PNG]] | ||
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| − | *'''Clicked on EC 2.7.1.112 link, the link brought up this page''' | + | *'''Clicked on EC 2.7.1.112 link, the link brought up this page. This page can help a person figure out a protein's enzymatic function.''' |
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| − | *'''I navigated back to the original page, then clicked on the Comments heading to see what the comments where. I was directed to this page.''' | + | *'''I navigated back to the original page, then clicked on the Comments heading to see what the comments where. I was directed to this page. The comments page hold useful information that just doesn't fit under any of the other headings.''' |
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| − | *'''Again, I went back to the main page and scrolled down to the cross reference section. I found InterPro and clicked on a link for Graphical View. | + | *'''Again, I went back to the main page and scrolled down to the cross reference section. I found InterPro and clicked on a link for Graphical View. The page showed a visual for the domains and repeats of the protein.''' |
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| − | *'''I also clicked on EMBL, this is the page that showed up.''' | + | *'''I also clicked on EMBL, this is the page that showed up. EMBL showed some basic information about the sequence I clicked on, and showed where repeats occured on the gene.''' |
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| − | *'''I looked at PDB which gave an animation of the protein.''' | + | *'''I looked at PDB which gave an animation of the protein. I liked this page because it showed you the different domains on the protein.''' |
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| − | *'''For the Pfam Link, this | + | *'''For the Pfam Link, I clicked on the graphical view and got this. The image shows the arrangement of Pfam domains on the P00533 sequence.''' |
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| − | :[[Image: | + | :[[Image:Pfam.PNG]] |
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| − | *'''I tried out RefSeq, which gave a list of papers where the sequence was referenced.''' | + | *'''I tried out RefSeq, which gave a list of papers where the sequence was referenced. This could be useful in finding out more for a research project.''' |
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:[[Image:Lena12.PNG]] | :[[Image:Lena12.PNG]] | ||
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| + | *'''Lastly, under the Cross-refs, I tried out GeneID, which gave me this. It gave some general information and showed where the sequence was located genomically.''' | ||
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| + | [[Image:GeneID.png]] | ||
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Revision as of 23:51, 26 September 2013
Electronic Journal for Uniprot exercise
- searched for primary accession number: P00533
- This is what the entry showed. It it the main page containing general information about EGFR.
- Clicked on EC 2.7.1.112 link, the link brought up this page. This page can help a person figure out a protein's enzymatic function.
- I navigated back to the original page, then clicked on the Comments heading to see what the comments where. I was directed to this page. The comments page hold useful information that just doesn't fit under any of the other headings.
- Again, I went back to the main page and scrolled down to the cross reference section. I found InterPro and clicked on a link for Graphical View. The page showed a visual for the domains and repeats of the protein.
- I also clicked on EMBL, this is the page that showed up. EMBL showed some basic information about the sequence I clicked on, and showed where repeats occured on the gene.
- I looked at PDB which gave an animation of the protein. I liked this page because it showed you the different domains on the protein.
- For the Pfam Link, I clicked on the graphical view and got this. The image shows the arrangement of Pfam domains on the P00533 sequence.
- I tried out RefSeq, which gave a list of papers where the sequence was referenced. This could be useful in finding out more for a research project.
- Lastly, under the Cross-refs, I tried out GeneID, which gave me this. It gave some general information and showed where the sequence was located genomically.
- Back on the main page, under the heading Ontologies, there were some keywords listed. I clicked on the keyword Tumor Supressor.
- On the main page, under Sequence Annotation, this is what shows up
- I clicked on FASTA on the top right corner to get protein sequence in plain text. Here is the result
- >sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo sapiens GN=EGFR PE=1 SV=2
MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEV VLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALA VLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDF QNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGC TGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYV VTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFK NCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAF ENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKL FGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCN LLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVM GENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVV ALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGS GAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGI CLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAA RNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSY GVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPK FRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQ QGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTED SIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLN TVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRV APQSSEFIGA
