|
|
| | #*Click on the "Search" button to search for an article satisfying the filters that were set. | | #*Click on the "Search" button to search for an article satisfying the filters that were set. |
| | #Go to the last page of the search results. Since you are looking for the first description of the reference genome for the species of interest, the journal article you are looking for will probably be one of the older articles that come up in the search. | | #Go to the last page of the search results. Since you are looking for the first description of the reference genome for the species of interest, the journal article you are looking for will probably be one of the older articles that come up in the search. |
| | + | #*Reference genome article for ''C. trachomatis'': Stephens, R.S., Kalman, S., Lammel, C., Fan, J., Marathe, R., Aravind, L.,... Davis, R.W. (1998) Genome sequence of an obligate intracellular pathogen of humans: Chlamydia trachomatis. Science 282: 754-759. |
| | #Click on the link of an article that seems promising. If, after reading the abstract, you believe that this is the article that you are looking for, click on one of the links in the top right under "Links to full text" to retrieve the full article. | | #Click on the link of an article that seems promising. If, after reading the abstract, you believe that this is the article that you are looking for, click on one of the links in the top right under "Links to full text" to retrieve the full article. |
| | + | #Go to the Web of Science database through the link provided in the [http://libguides.lmu.edu/BIOL367 LibGuide] for the class. |
| | + | #In the first blank search field, type in part of the title of the article about the reference genome. |
| | + | #*For the article aforementioned, I typed in "obligate intracellular pathogen". |
| | + | #In the drop down menu to the right, select "Title". |
| | + | #In the next blank search field, type in the author's name. |
| | + | #*For the article aforementioned, I typed in "Stephens". |
| | + | #Click on the "Search" button. One of the results should be the article that you found on the reference genome. |
| | + | #In the citation for the result that matches the title of the article about the reference genome, click on the link that designates the number of times that the article was cited. |
| | | | |
| | ==Locate journal articles that measure gene expression== | | ==Locate journal articles that measure gene expression== |
| | | | |
| | + | ===Locating microarray data on EBI ArrayExpress=== |
| | + | #Go to the [http://www.ebi.ac.uk/arrayexpress/ EBI ArrayExpress] database. |
| | + | #Click on "Experiments" in the navigation toolbar toward the top of the website. |
| | + | #Go to the "By organism" drop down menu in the "Filter Experiments" section. Select the species ''Chlamydia trachomatis''. |
| | + | #Click on the "Filter" button to locate the microarray datasets on the database for the selected species. |
| | + | #Click on one of the links in the "Accession" column to go to the page in the database that contains the microarray data for the experiment designated by that accession number. You will be taken to a site that has a table of various information. |
| | + | #*For example, click on the link "E-GEOD-10199". This takes you to a page titled "E-GEOD-10199 - Glycogen Accumulation in Chlamydia trachomatis is Controlled by its Plasmid Through Regulation of glgA". |
| | + | #*'''Note: The data under the accession number E-GEOD-24119 has not been published in a journal.''' |
| | + | #Scroll down to the last row of the table with the designation "Links". Click on the first link in the row, which is in the format "GEO - GSE10199". This will take you to a page on the [http://www.ncbi.nlm.nih.gov/geo NCBI GEO] database, which will contain the citation for the article published regarding the data (if an article was published). |
| | + | #*For the page opened by clicking on the accession number "E-GEOD-10199", click on the link "GEO - GSE10199" in the "Links" row. |
| | + | #Copy and Paste the name of the article listed in the citation into the search field in [http://scholar.google.com/ Google Scholar]. |
| | + | #*For instance, the name of the journal article corresponding to the data with the aforementioned accession number is "The Chlamydia trachomatis plasmid is a transcriptional regulator of chromosomal genes and a virulence factor". |
| | + | #Click on the link in the search results that matches the name of the article. This will take you to the site that contains the article. |
| | + | |
| | + | ===Locating journal articles published on microarray datasets not in EBI ArrayExpress=== |
| | #Go to the PubMed site through the link provided in the [http://libguides.lmu.edu/BIOL367 LibGuide] for the class. | | #Go to the PubMed site through the link provided in the [http://libguides.lmu.edu/BIOL367 LibGuide] for the class. |
| | #Beneath the search bar at the top of the page, click on the "Advanced" link. | | #Beneath the search bar at the top of the page, click on the "Advanced" link. |
|
|
| | #*In the drop down menu to the left of this field, select "Title/Abstract". | | #*In the drop down menu to the left of this field, select "Title/Abstract". |
| | #Click on the "Search" button to search for articles meeting the filter criteria. | | #Click on the "Search" button to search for articles meeting the filter criteria. |
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