Difference between revisions of "Week 2"
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'''This journal entry is due on Friday, September 6, at midnight PDT.''' ''(Thursday night/Friday morning)'' | '''This journal entry is due on Friday, September 6, at midnight PDT.''' ''(Thursday night/Friday morning)'' | ||
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# How was the genetic code solved experimentally? | # How was the genetic code solved experimentally? | ||
# What is the relationship between the genetic code and a computer code? | # What is the relationship between the genetic code and a computer code? | ||
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{{Individual Journal Instructions|week=2}} | {{Individual Journal Instructions|week=2}} | ||
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| + | === Wiki Catch-up === | ||
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| + | If you missed practicing any wiki skills or doing any other tasks from [[Week 1]], wrap them up this week. | ||
=== The Genetic Code === | === The Genetic Code === | ||
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** Use the single-letter abbreviations for the amino acids because that is what is commonly used by computer programs. | ** Use the single-letter abbreviations for the amino acids because that is what is commonly used by computer programs. | ||
* Wiki Hint: if you start your line with a single space character, it will appear in the grey box surrounded by the dashed line as shown above. | * Wiki Hint: if you start your line with a single space character, it will appear in the grey box surrounded by the dashed line as shown above. | ||
| − | + | * Which of the reading frames (if any) of the reading frames you translated is an ''open reading frame'', i.e., does not contain a stop codon? | |
| − | + | ** By convention, the top strand frames are called +1, +2, +3, reading 5' to 3' and the bottom strand frames are called -1, -2, -3, reading 5' to 3'. | |
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[[Category:Journal Assignment]] | [[Category:Journal Assignment]] | ||
Latest revision as of 16:12, 3 September 2013
This journal entry is due on Friday, September 6, at midnight PDT. (Thursday night/Friday morning)
Contents |
[edit]
- Store your journal entry in the shared Class Journal Week 2 page. If this page does not exist yet, go ahead and create it (congratulations on getting in first :) )
- Link to your journal entry from your user page.
- Link back from the journal entry to your user page.
- NOTE: you can easily fulfill the links part of these instructions by adding them to your template and using the template on your user page.
- Sign your portion of the journal with the standard wiki signature shortcut (
~~~~). - Add the "Journal Entry" and "Shared" categories to the end of the wiki page (if someone has not already done so).
[edit] Read
- Brown, T.A. (2002) Genomes 2, Ch. 3.3.2: The link between the transcriptome and the proteome (freely available on NCBI Bookshelf)
- Nirenberg, M. (2004) Deciphering the Genetic Code—a Personal Account. Trends in Biochemical Sciences 29: 46-54. (on MyLMUConnect)
- Moody, G. (2004) Digital Code of Life, Chapter 1, Hoboken, New Jersey: John Wiley & Sons, pp. 1-9. (on MyLMUConnect)
- Hayes, B. (2004) Ode to the Code, American Scientist 92: 494-498. (on MyLMUConnect)
[edit] Reflect
[edit] Readings
- What is the biggest discovery that I made from these readings?
- What part of the readings did I understand the least?
- How was the genetic code solved experimentally?
- What is the relationship between the genetic code and a computer code?
[edit] Individual Journal Assignment
- Store this journal entry as "username Week 2" (i.e., this is the text to place between the square brackets when you link to this page).
- Link from your user page to this Assignment page.
- Link to your journal entry from your user page.
- Link back from your journal entry to your user page.
- Don't forget to add the "Journal Entry" category to the end of your wiki page.
- Note: you can easily fulfill all of these links by adding them to your template and then using your template on your journal entry.
[edit] Wiki Catch-up
If you missed practicing any wiki skills or doing any other tasks from Week 1, wrap them up this week.
[edit] The Genetic Code
- Write out the complementary strand of DNA below the strand shown and be sure to label the 5’ and 3’ ends of the complementary strand.
5’-cgtatgctaataccatgttccgcgtataacccagccgccagttccgctggcggcatttta-3’
- There are six possible reading frames in double-stranded DNA. Using the genetic code, translate all possible reading frames of this DNA sequence, keeping in mind the following rules.
- In RNA, the T becomes a U, so everywhere you see a T in the sequence, read it as a U.
- The genetic code is read in the 5’ to 3’ direction.
- Use the single-letter abbreviations for the amino acids because that is what is commonly used by computer programs.
- Wiki Hint: if you start your line with a single space character, it will appear in the grey box surrounded by the dashed line as shown above.
- Which of the reading frames (if any) of the reading frames you translated is an open reading frame, i.e., does not contain a stop codon?
- By convention, the top strand frames are called +1, +2, +3, reading 5' to 3' and the bottom strand frames are called -1, -2, -3, reading 5' to 3'.
