Difference between revisions of "Kevinmcgee Week 5"
From LMU BioDB 2013
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#*Geneid is a database that further identifies and describes the EFGR and how it relates to genes. For instance, it gives the location of EFGR on a chromosome, and how EFGR relates to patients with ling cancer. | #*Geneid is a database that further identifies and describes the EFGR and how it relates to genes. For instance, it gives the location of EFGR on a chromosome, and how EFGR relates to patients with ling cancer. | ||
#EFGR is a protein that is a receptor for the epidermal growth factor and is also a member of the kinase family. If bonded to a ligand, it leads to cell proliferation. Found on the surface of a cell. EFGR mutations have also been known to be associated with lung cancer. | #EFGR is a protein that is a receptor for the epidermal growth factor and is also a member of the kinase family. If bonded to a ligand, it leads to cell proliferation. Found on the surface of a cell. EFGR mutations have also been known to be associated with lung cancer. | ||
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| + | #*The purpose of this assignment was to understand all the different datatbases used in biology and how they interrelate to one another. | ||
| + | #*I learned about the different types of databases and about the properties of EFGR. | ||
| + | #*I am still confused as to why there are so many different databases, and why they cannot keep all the information on a single database. It seems easier to me to have all the information in one place. | ||
Latest revision as of 22:37, 25 September 2013
[edit] Uniprot Exercise
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- EMBL stands for European Molecular Biology Lab. It is a database that holds a large amount of protein/gene databases. Similar to Genbank and DDBJ
- InterPro is a database for protein sequence, analysis, and classification. Owned by the European Bioinformatics Institute (EBI).
- On Uniprot, there are three different PDB databases. PDB stands for Protein Data Bank, and they contain 3D structures of proteins.
- Pfam is a collection of protein domains to easily look at the domains of a protein and what that tells us about that protein.
- RefSeq stands for Reference Sequence collection, which is a US owned database of protein, DNA, and gene sequences. It provides summaries and documents on the sequences it contains.
- Geneid is a database that further identifies and describes the EFGR and how it relates to genes. For instance, it gives the location of EFGR on a chromosome, and how EFGR relates to patients with ling cancer.
- EFGR is a protein that is a receptor for the epidermal growth factor and is also a member of the kinase family. If bonded to a ligand, it leads to cell proliferation. Found on the surface of a cell. EFGR mutations have also been known to be associated with lung cancer.
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- The purpose of this assignment was to understand all the different datatbases used in biology and how they interrelate to one another.
- I learned about the different types of databases and about the properties of EFGR.
- I am still confused as to why there are so many different databases, and why they cannot keep all the information on a single database. It seems easier to me to have all the information in one place.
