Difference between revisions of "Ksherbina Week 11"

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(Outline of the Article: Added some information about the significance of the genome paper.)
(10 Biological Terms from Paper: Added definitions for three terms.)
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==10 Biological Terms from Paper==
 
==10 Biological Terms from Paper==
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*Biovar - A strain differentiated from other strains by biochemical or other non-serological means.
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:Abedon, S. T. Supplemental Lecture (98/04/14 update). <http://www.mansfield.ohio-state.edu/~sabedon/biol3010.htm>. Accessed 10 November 2013.
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*Hydrodynamic shearing - A technique that fragments DNA molecules by forcing them through a small orifice or the bore of a small-diameter tube at high velocity.
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:Joneja, A. & Huang, X. Supplementary Material For: A device for automated hydrodynamic shearing of genomic DNA. ''BioTechniques'' '''46''': 553–556.
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*Serology - A type of laboratory medicine that analyzes blood serum for signs of infection by looking at antigen-antibody interactions ''in vivo''.
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:Serology. (n.d.). Medical-Dictionary. <http://medical-dictionary.thefreedictionary.com/serology>. Accessed 10 November 2013.
  
 
==Outline of the Article==
 
==Outline of the Article==

Revision as of 02:58, 11 November 2013

Katrina Sherbina
Class Page    User Page
Assignment Description Week 1 Week 2 Week 3 Week 4 Week 5 Week 6 Week 7 Week 8 Week 9 Week 10 Week 11 Week 12 Week 13 Week 15
Class Journal Week 1 Week 2 Week 3 Week 4 Week 5 Week 6 Week 7 Week 8 Week 9
Individual Journal Week 2 Week 3 Week 4 Week 5 Week 6 Week 7 Week 8 Week 9 Week 10 Week 11
Other Week 5: Database Wiki
Final Project Team H(oo)KD Project Page Journal Club Presentation Project Individual Journal

Paper for Journal Club:

Stephens, R.S., Kalman, S., Lammel, C., Fan, J., Marathe, R., Aravind, L., Mitchell, W., Olinger, L., Tatusov, R., Zhao, Q., Koonin, E. V., Davis, R.W. (1998) Genome sequence of an obligate intracellular pathogen of humans: Chlamydia trachomatis. Science 282: 754-759. doi: 10.1126/science.282.5389.754

Contents

10 Biological Terms from Paper

  • Biovar - A strain differentiated from other strains by biochemical or other non-serological means.
Abedon, S. T. Supplemental Lecture (98/04/14 update). <http://www.mansfield.ohio-state.edu/~sabedon/biol3010.htm>. Accessed 10 November 2013.
  • Hydrodynamic shearing - A technique that fragments DNA molecules by forcing them through a small orifice or the bore of a small-diameter tube at high velocity.
Joneja, A. & Huang, X. Supplementary Material For: A device for automated hydrodynamic shearing of genomic DNA. BioTechniques 46: 553–556.
  • Serology - A type of laboratory medicine that analyzes blood serum for signs of infection by looking at antigen-antibody interactions in vivo.
Serology. (n.d.). Medical-Dictionary. <http://medical-dictionary.thefreedictionary.com/serology>. Accessed 10 November 2013.

Outline of the Article

Importance of sequencing the Chlamydia trachomatis genome

  • C. trachomatis causes several diseases in human beings, including trachoma, which leads to blindness.
  • C. trachomatis infections in humans may increase the risk of HIV infection.
  • At the time the article was released, little was known about the two developmental stages of C. trachomatis (i.e. the elementary body and the reticulate body) as well as the bacterial pathogen's physiology and genetics.

Model Organism Database

http://efaecalis.mlst.net/ http://liferay.csb.univie.ac.at/portal/web/chlamydiaedb

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