Difference between revisions of "Kmeilak Week 5"

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#InterPro - This database has textual information describing the function, and sometimes morphology and bodily significance, of particular protein domains and families.
 
#InterPro - This database has textual information describing the function, and sometimes morphology and bodily significance, of particular protein domains and families.
 
#PDB - This database has information focusing on the 3-dimensional structure of proteins, and has information concerning the domains that comprise the protein.
 
#PDB - This database has information focusing on the 3-dimensional structure of proteins, and has information concerning the domains that comprise the protein.
#Pfam -
+
#Pfam - This database has information from its own archives and other databases about protein families and domains. It includes a 3-dimensional graphic of the protein or domain but focuses on providing links to all sources of information.
 +
#RefSeq -

Revision as of 23:26, 22 September 2013

UniProt Lab Journal

  • Entered Primary Accession Number P00533 into UniProt Query; was directed to page for that particular protein, aka EGFR_HUMAN.
  • Followed link of E.C. number of protein, found and highlighted P00533 in list on this page.
  • Followed highlighted link for P00533, which returned me to P00533 page. Kept this page open and opened E.C. page in a new tab.
  • Found description near top of the page for P00533 under General Annotation (Comments) Section including function, catalytic activity, and tissue specificity, among others.
  • Clicked on Cross-Reference tab at top of P00533 page which took me to that section of the page. Below are the descriptions of information found on different databases asked for in the homework assignment.
  1. EMBL - This database has information concerning genomic DNA, mRNA, and their translation into protein. It lists the base pair sequences for a particular gene as found in its genomic DNA or mRNA sequence, and a graphic displaying what parts of that gene are significant in affecting the final protein product.
  2. InterPro - This database has textual information describing the function, and sometimes morphology and bodily significance, of particular protein domains and families.
  3. PDB - This database has information focusing on the 3-dimensional structure of proteins, and has information concerning the domains that comprise the protein.
  4. Pfam - This database has information from its own archives and other databases about protein families and domains. It includes a 3-dimensional graphic of the protein or domain but focuses on providing links to all sources of information.
  5. RefSeq -
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