Difference between revisions of "Chlamydia trachomatis"
From LMU BioDB 2013
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#*Based on the titles and abstracts of the papers, what type of research directions have been taken now that the genome for that organism has been sequenced?: Based on the titles and abstracts found in the results, it seems that research has been primarily in the direction of understanding how the disease functions and assessing the severity of the disease (and how to cure it). | #*Based on the titles and abstracts of the papers, what type of research directions have been taken now that the genome for that organism has been sequenced?: Based on the titles and abstracts found in the results, it seems that research has been primarily in the direction of understanding how the disease functions and assessing the severity of the disease (and how to cure it). | ||
| − | ===Microarray articles=== | + | ===Microarray articles=== |
| − | + | The EBI ArrayExpress database was used to locate each of the four following microarray articles. The search terms used were Chlamydia trachomatis under 'By organism' while the rest of the drop down menus were not altered. | |
| − | + | #Song L, Carlson JH, Whitmire WM, Kari L et al. [http://iai.asm.org/content/81/3/636.long Chlamydia trachomatis plasmid-encoded Pgp4 is a transcriptional regulator of virulence-associated genes.] Infect Immun 2013 Mar;81(3):636-44. | |
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| − | # | + | #Carlson JH, Whitmire WM, Crane DD, Wicke L et al. [http://iai.asm.org/content/76/6/2273.long The Chlamydia trachomatis plasmid is a transcriptional regulator of chromosomal genes and a virulence factor.] Infect Immun 2008 Jun;76(6):2273-83. |
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#What experiment was performed? What was the "treatment" and what was the "control" in the experiment? | #What experiment was performed? What was the "treatment" and what was the "control" in the experiment? | ||
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#Were replicate experiments of the "treatment" and "control" conditions conducted? Were these biological or technical replicates? How many of each? | #Were replicate experiments of the "treatment" and "control" conditions conducted? Were these biological or technical replicates? How many of each? | ||
| − | # | + | #What experiment was performed? What was the "treatment" and what was the "control" in the experiment? |
| + | #Were replicate experiments of the "treatment" and "control" conditions conducted? Were these biological or technical replicates? How many of each? | ||
Revision as of 02:28, 1 November 2013
Team 1: Chlamydia trachomatis
Annotated Bibliography of Genomics Papers for C. trachomatis
Whole genome sequencing of C. trachomatis
- Journal article describing results of whole genome sequencing:
- Database: PubMed
- Search Terms: Chlamydia trachomatis [MeSH Term] AND genome [Title]
- Stephens, R.S., Kalman, S., Lammel, C., Fan, J., Marathe, R., Aravind, L.,... Davis, R.W. (1998) Genome sequence of an obligate intracellular pathogen of humans: Chlamydia trachomatis. Science 282: 754-759.
- Use the genome sequencing article you found to perform a prospective search in the ISI Web of Science/Knowledge database.
- How many results did you get?: 872
- Based on the titles and abstracts of the papers, what type of research directions have been taken now that the genome for that organism has been sequenced?: Based on the titles and abstracts found in the results, it seems that research has been primarily in the direction of understanding how the disease functions and assessing the severity of the disease (and how to cure it).
Microarray articles
The EBI ArrayExpress database was used to locate each of the four following microarray articles. The search terms used were Chlamydia trachomatis under 'By organism' while the rest of the drop down menus were not altered.
- Song L, Carlson JH, Whitmire WM, Kari L et al. Chlamydia trachomatis plasmid-encoded Pgp4 is a transcriptional regulator of virulence-associated genes. Infect Immun 2013 Mar;81(3):636-44.
- Carlson JH, Whitmire WM, Crane DD, Wicke L et al. The Chlamydia trachomatis plasmid is a transcriptional regulator of chromosomal genes and a virulence factor. Infect Immun 2008 Jun;76(6):2273-83.
- What experiment was performed? What was the "treatment" and what was the "control" in the experiment?
- Were replicate experiments of the "treatment" and "control" conditions conducted? Were these biological or technical replicates? How many of each?
- What experiment was performed? What was the "treatment" and what was the "control" in the experiment?
- Were replicate experiments of the "treatment" and "control" conditions conducted? Were these biological or technical replicates? How many of each?
