Ksherbina Week 11

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Katrina Sherbina
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Final Project Team H(oo)KD Project Page Journal Club Presentation Project Individual Journal

Paper for Journal Club:

Stephens, R.S., Kalman, S., Lammel, C., Fan, J., Marathe, R., Aravind, L., Mitchell, W., Olinger, L., Tatusov, R., Zhao, Q., Koonin, E. V., Davis, R.W. (1998) Genome sequence of an obligate intracellular pathogen of humans: Chlamydia trachomatis. Science 282: 754-759. doi: 10.1126/science.282.5389.754

Contents

10 Biological Terms from Paper

Outline of the Article

Importance of sequencing the Chlamydia trachomatis genome

  • C. trachomatis causes several diseases in human beings, including trachoma, which leads to blindness.
  • C. trachomatis infections in humans may increase the risk of HIV infection.
  • At the time the article was released, little was known about the two developmental stages of C. trachomatis (i.e. the elementary body and the reticulate body) as well as the bacterial pathogen's physiology and genetics.

Model Organism Database

http://efaecalis.mlst.net/ http://liferay.csb.univie.ac.at/portal/web/chlamydiaedb

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