Vkuehn Week 5

UniProt Exercise

• Opened and read Bioinformatics For Dummies
• The location where Proteins end up and how they get there are unique

• The folding and domains are very important and help determine the 3D structure
• Searched for the protein P00533 it is an epidermal growth factor receptor
• Here are the results:

• As new information comes out, older accession numbers don't go away, they just get stored as secondary accession numbers, but the most up to date information is only displayed
• The comments section is very useful for gathering information about the protein such as: function, catalytic activity, tissue specificity
• The cross-reference section is very useful for gathering other information in new databases. For example, EMBL-EBI gives a visual overview of the base pairs and other details:

[[1]]

• Here is an example of a 3D database result for the epidermal protein:

[[2]]