Lena Week 10

Electronic Lab Notebook

Genome sequencing for leishmania

• The main paper for our group is The genome of the kinetoplastid parasite, Leishmania major.
• Ivens, AC et al. 2005 Jul 15. The genome of the kinetoplastid parasite, Leishmania major. Science;309(5733):436-42.

prospective search

• For the prospective search, I used web of knowledge to search for the keywords leishmania and genome in the titles of articles. The search produced 59 results.
• The first few results were highly specific, so I went to the last page and searched backwards. On the last page there were some good general studies. I linked to my favorites above as I was working.

microarray data

• I used the arrayexpress search to look for the species leishmania major. There were 12 experiments found, but only 5 were transcription profiling by array. None of the ones I searched through had papers associated with them that I could find. I searched for authors and keye words in Google Scholar and PubMed to no avail.

• I found some good articles outlining how mircoarray experiments were used on the leishmania genome, but then I could not find the raw data associated with it. Luckily my group members had more luck and pointed me in the way of some good papers.

Lena Hunt