MAPPFinder 2.0 Results for the Gene Ontology File: T:\Lena\final GenMAPP analysis\Bpertussis_CompiledRawData_MS2015-3.gex Table: geneontologyresults-Criterion0-GO Database: T:\Lena\bpertussis-std_cw20151210.gdb colors:|LogFoldChange| 12/11/2015 Bordetella pertussis Pvalues = true Calculation Summary: 869 probes met the [Avg_ABC_Samples] > 0.25 AND [Pvalue] < 0.05 criteria. 813 probes meeting the filter linked to a UniProt ID. 642 genes meeting the criterion linked to a GO term. 3549 Probes in this dataset 3211 Probes linked to a UniProt ID. 2635 Genes linked to a GO term. The z score is based on an N of 2635 and a R of 642 distinct genes in the GO. GOID GO Name GO Type Number Changed Local Number Measured Local Number in GO Local Percent Changed Local Percent Present Local Number Changed Number Measured Number in GO Percent Changed Percent Present Z Score PermuteP AdjustedP 0009405 pathogenesis P 16 18 18 88.88889 100 16 18 18 88.88889 100 6.398 0 0 0051704 multi-organism process P 0 0 0 0 0 20 27 18 74.07407 150 6.047 0 0 0006457 protein folding P 11 17 17 64.70588 100 13 19 19 68.42105 100 4.489 0 0.01 0016020 membrane C 137 690 691 19.85507 99.85529 149 737 695 20.2171 106.0432 -3.09 0 0.689 0019843 rRNA binding F 1 39 39 2.564103 100 1 39 39 2.564103 100 -3.195 0 0.642 0005622 intracellular C 16 112 112 14.28571 100 82 457 402 17.94311 113.6816 -3.517 0 0.425 0044699 single-organism process P 0 0 0 0 0 232 1110 359 20.9009 309.1922 -3.533 0 0.259 0044424 intracellular part C 0 0 0 0 0 66 390 335 16.92308 116.4179 -3.708 0 0.225 0005198 structural molecule activity F 2 7 7 28.57143 100 2 61 61 3.278688 100 -3.881 0 0.143 0044763 single-organism cellular process P 0 0 0 0 0 154 794 1 19.39547 79400 -3.901 0 0.134 0043603 cellular amide metabolic process P 0 0 0 0 0 15 143 99 10.48951 144.4444 -3.974 0 0.075 0005575 cellular_component C 0 0 0 0 0 272 1300 115 20.92308 1130.435 -4.06 0 0.064 0003735 structural constituent of ribosome F 0 54 54 0 100 0 54 54 0 100 -4.213 0 0.03 0005840 ribosome C 0 55 55 0 100 0 55 55 0 100 -4.253 0 0.028 0003723 RNA binding F 4 77 77 5.194805 100 6 98 78 6.122449 125.641 -4.286 0 0.028 0030529 intracellular ribonucleoprotein complex C 0 55 55 0 100 0 56 56 0 100 -4.292 0 0.028 1990904 ribonucleoprotein complex C 0 0 0 0 0 0 56 56 0 100 -4.292 0 0.028 0006518 peptide metabolic process P 0 0 0 0 0 8 111 99 7.207207 112.1212 -4.302 0 0.028 0006412 translation P 6 96 96 6.25 100 7 105 99 6.666667 106.0606 -4.31 0 0.025 0043043 peptide biosynthetic process P 0 1 1 0 100 7 107 99 6.542056 108.0808 -4.384 0 0.014 0043604 amide biosynthetic process P 0 0 0 0 0 10 128 99 7.8125 129.2929 -4.471 0 0.01 0043228 non-membrane-bounded organelle C 0 0 0 0 0 4 92 55 4.347826 167.2727 -4.552 0 0.007 0043226 organelle C 0 0 0 0 0 4 92 55 4.347826 167.2727 -4.552 0 0.007 0043229 intracellular organelle C 0 0 0 0 0 0 66 55 0 120 -4.669 0 0.004 0043232 intracellular non-membrane-bounded organelle C 0 0 0 0 0 0 66 55 0 120 -4.669 0 0.004 0016226 iron-sulfur cluster assembly P 5 6 6 83.33334 100 6 7 7 85.71429 100 3.785 0.001 0.186 0031163 metallo-sulfur cluster assembly P 0 0 0 0 0 6 7 7 85.71429 100 3.785 0.001 0.186 0070887 cellular response to chemical stimulus P 0 0 0 0 0 6 8 4 75 200 3.341 0.001 0.594 0044238 primary metabolic process P 0 0 0 0 0 207 969 44 21.36223 2202.273 -2.737 0.001 0.99 0009987 cellular process P 0 0 0 0 0 292 1334 4 21.88906 33350 -2.997 0.001 0.945 0008610 lipid biosynthetic process P 0 3 3 0 100 3 52 9 5.769231 577.7778 -3.154 0.001 0.659 0006812 cation transport P 1 7 7 14.28571 100 3 52 28 5.769231 185.7143 -3.154 0.001 0.659 0016740 transferase activity F 59 315 316 18.73016 99.68355 65 367 317 17.71117 115.7729 -3.2 0.001 0.641 0044444 cytoplasmic part C 0 0 0 0 0 7 79 55 8.86076 143.6364 -3.259 0.001 0.619 0042178 xenobiotic catabolic process P 0 0 0 0 0 4 4 4 100 100 3.526 0.002 0.425 0009410 response to xenobiotic stimulus P 0 0 0 0 0 4 4 4 100 100 3.526 0.002 0.425 0006805 xenobiotic metabolic process P 0 0 0 0 0 4 4 4 100 100 3.526 0.002 0.425 0071466 cellular response to xenobiotic stimulus P 0 0 0 0 0 4 4 4 100 100 3.526 0.002 0.425 0010124 phenylacetate catabolic process P 4 4 4 100 100 4 4 4 100 100 3.526 0.002 0.425 0005515 protein binding F 0 0 0 0 0 14 26 7 53.84615 371.4286 3.519 0.002 0.425 0071941 nitrogen cycle metabolic process P 0 0 0 0 0 5 6 1 83.33334 600 3.368 0.002 0.536 0001071 nucleic acid binding transcription factor activity F 0 0 0 0 0 58 173 173 33.52601 100 2.903 0.002 0.973 0003700 transcription factor activity, sequence-specific DNA binding F 58 173 173 33.52601 100 58 173 173 33.52601 100 2.903 0.002 0.973 0044425 membrane part C 0 0 0 0 0 132 659 621 20.03035 106.1192 -2.992 0.002 0.945 0005737 cytoplasm C 59 281 281 20.99644 100 63 351 335 17.94872 104.7761 -3.007 0.002 0.943 0005975 carbohydrate metabolic process P 3 37 37 8.108109 100 7 75 44 9.333333 170.4545 -3.076 0.002 0.697 1901137 carbohydrate derivative biosynthetic process P 0 1 1 0 100 9 92 4 9.782609 2300 -3.316 0.002 0.603 0044267 cellular protein metabolic process P 0 0 0 0 0 23 168 99 13.69048 169.697 -3.33 0.002 0.594 0005576 extracellular region C 9 13 13 69.23077 100 9 14 14 64.28571 100 3.488 0.003 0.435 0051082 unfolded protein binding F 8 12 12 66.66666 100 8 12 12 66.66666 100 3.421 0.003 0.457 0019363 pyridine nucleotide biosynthetic process P 4 6 6 66.66666 100 6 8 7 75 114.2857 3.341 0.003 0.594 0019674 NAD metabolic process P 1 1 1 100 100 6 8 8 75 100 3.341 0.003 0.594 0019359 nicotinamide nucleotide biosynthetic process P 0 0 0 0 0 6 8 7 75 114.2857 3.341 0.003 0.594 0003674 molecular_function F 0 0 0 0 0 469 2032 556 23.08071 365.4676 -2.817 0.003 0.987 0003824 catalytic activity F 92 332 332 27.71084 100 309 1416 556 21.82203 254.6763 -3.276 0.003 0.617 1901135 carbohydrate derivative metabolic process P 0 0 0 0 0 18 141 3 12.76596 4700 -3.297 0.003 0.61 0009628 response to abiotic stimulus P 0 0 0 0 0 4 4 3 100 133.3333 3.526 0.004 0.425 0019627 urea metabolic process P 3 3 3 100 100 4 4 4 100 100 3.526 0.004 0.425 0042537 benzene-containing compound metabolic process P 0 0 0 0 0 7 10 2 70 500 3.367 0.004 0.556 0016021 integral component of membrane C 123 620 621 19.83871 99.83897 132 650 621 20.30769 104.6699 -2.775 0.004 0.987 0031224 intrinsic component of membrane C 0 0 0 0 0 132 651 621 20.2765 104.8309 -2.799 0.004 0.987 0044237 cellular metabolic process P 0 3 3 0 100 217 1040 4 20.86539 26000 -3.378 0.004 0.47 0043657 host cell C 0 0 0 0 0 4 4 4 100 100 3.526 0.005 0.425 0044217 other organism part C 0 0 0 0 0 4 4 4 100 100 3.526 0.005 0.425 0033643 host cell part C 0 0 0 0 0 4 4 4 100 100 3.526 0.005 0.425 0044218 other organism cell membrane C 0 0 0 0 0 4 4 4 100 100 3.526 0.005 0.425 0044279 other organism membrane C 0 0 0 0 0 4 4 4 100 100 3.526 0.005 0.425 0020002 host cell plasma membrane C 4 4 4 100 100 4 4 4 100 100 3.526 0.005 0.425 0044215 other organism C 0 0 0 0 0 4 4 4 100 100 3.526 0.005 0.425 0018995 host C 0 0 0 0 0 4 4 4 100 100 3.526 0.005 0.425 0044216 other organism cell C 0 0 0 0 0 4 4 4 100 100 3.526 0.005 0.425 0033644 host cell membrane C 4 4 4 100 100 4 4 4 100 100 3.526 0.005 0.425 0006355 regulation of transcription, DNA-templated P 86 269 269 31.97026 100 87 270 269 32.22222 100.3717 3.174 0.005 0.651 1901566 organonitrogen compound biosynthetic process P 0 0 0 0 0 58 334 99 17.36527 337.3737 -3.188 0.005 0.645 0019219 regulation of nucleobase-containing compound metabolic process P 0 0 0 0 0 88 274 270 32.11679 101.4815 3.157 0.006 0.655 0051252 regulation of RNA metabolic process P 0 0 0 0 0 87 271 270 32.10332 100.3704 3.133 0.006 0.663 2001141 regulation of RNA biosynthetic process P 0 0 0 0 0 87 271 270 32.10332 100.3704 3.133 0.006 0.663 1903506 regulation of nucleic acid-templated transcription P 0 1 1 0 100 87 271 270 32.10332 100.3704 3.133 0.006 0.663 0006351 transcription, DNA-templated P 78 248 248 31.45161 100 88 276 275 31.88406 100.3636 3.075 0.006 0.697 0097659 nucleic acid-templated transcription P 0 0 0 0 0 88 277 275 31.76895 100.7273 3.034 0.006 0.943 0016051 carbohydrate biosynthetic process P 0 1 1 0 100 1 28 11 3.571429 254.5455 -2.576 0.006 0.995 0016310 phosphorylation P 10 62 62 16.12903 100 10 82 71 12.19512 115.493 -2.607 0.006 0.995 0044711 single-organism biosynthetic process P 0 0 0 0 0 50 290 69 17.24138 420.2899 -2.995 0.006 0.945 0008324 cation transmembrane transporter activity F 0 4 4 0 100 3 42 10 7.142857 420 -2.62 0.007 0.995 0098655 cation transmembrane transport P 0 5 5 0 100 2 36 27 5.555555 133.3333 -2.647 0.007 0.991 0016772 transferase activity, transferring phosphorus-containing groups F 3 22 22 13.63636 100 14 108 56 12.96296 192.8571 -2.818 0.007 0.987 1901564 organonitrogen compound metabolic process P 0 0 0 0 0 76 418 99 18.18182 422.2222 -3.209 0.007 0.638 0006644 phospholipid metabolic process P 0 2 2 0 100 1 29 6 3.448276 483.3333 -2.638 0.008 0.991 0019439 aromatic compound catabolic process P 1 5 5 20 100 13 27 9 48.14815 300 2.893 0.009 0.987 0032549 ribonucleoside binding F 0 1 1 0 100 59 316 293 18.67089 107.8498 -2.513 0.009 0.997 0001882 nucleoside binding F 0 0 0 0 0 59 316 292 18.67089 108.2192 -2.513 0.009 0.997 0009039 urease activity F 3 3 3 100 100 3 3 3 100 100 3.053 0.01 0.94 0043419 urea catabolic process P 3 3 3 100 100 3 3 3 100 100 3.053 0.01 0.94 0006811 ion transport P 1 18 18 5.555555 100 16 110 36 14.54545 305.5555 -2.45 0.01 1 0015672 monovalent inorganic cation transport P 0 1 1 0 100 2 35 23 5.714286 152.1739 -2.587 0.01 0.995 0071704 organic substance metabolic process P 1 3 3 33.33333 100 234 1076 44 21.74721 2445.455 -2.599 0.01 0.995 0016779 nucleotidyltransferase activity F 1 34 34 2.941176 100 2 38 35 5.263158 108.5714 -2.762 0.01 0.987 2000112 regulation of cellular macromolecule biosynthetic process P 0 0 0 0 0 89 283 269 31.44876 105.2045 2.938 0.011 0.96 0031323 regulation of cellular metabolic process P 0 0 0 0 0 90 287 270 31.35888 106.2963 2.924 0.011 0.962 0009435 NAD biosynthetic process P 5 7 7 71.42857 100 5 7 7 71.42857 100 2.904 0.011 0.973 0031326 regulation of cellular biosynthetic process P 0 0 0 0 0 89 284 270 31.33803 105.1852 2.898 0.011 0.987 0010556 regulation of macromolecule biosynthetic process P 0 0 0 0 0 89 284 270 31.33803 105.1852 2.898 0.011 0.987 0010468 regulation of gene expression P 2 4 4 50 100 89 284 270 31.33803 105.1852 2.898 0.011 0.987 0051171 regulation of nitrogen compound metabolic process P 0 0 0 0 0 89 285 270 31.22807 105.5556 2.858 0.011 0.987 0032774 RNA biosynthetic process P 0 0 0 0 0 88 282 275 31.20567 102.5455 2.832 0.011 0.987 1901361 organic cyclic compound catabolic process P 0 0 0 0 0 11 23 4 47.82609 575 2.632 0.011 0.991 0035639 purine ribonucleoside triphosphate binding F 0 0 0 0 0 59 315 292 18.73016 107.8767 -2.482 0.011 1 0032550 purine ribonucleoside binding F 0 0 0 0 0 59 315 292 18.73016 107.8767 -2.482 0.011 1 0001883 purine nucleoside binding F 0 0 0 0 0 59 315 292 18.73016 107.8767 -2.482 0.011 1 0022891 substrate-specific transmembrane transporter activity F 0 1 1 0 100 11 85 12 12.94118 708.3333 -2.493 0.011 0.997 0022857 transmembrane transporter activity F 2 3 3 66.66666 100 16 111 19 14.41441 584.2105 -2.495 0.011 0.997 0016783 sulfurtransferase activity F 2 3 3 66.66666 100 4 5 4 80 125 2.9 0.012 0.987 0019222 regulation of metabolic process P 0 0 0 0 0 92 295 270 31.18644 109.2593 2.896 0.012 0.987 0009889 regulation of biosynthetic process P 0 0 0 0 0 89 285 270 31.22807 105.5556 2.858 0.012 0.987 0060255 regulation of macromolecule metabolic process P 0 0 0 0 0 90 290 270 31.03448 107.4074 2.804 0.012 0.987 0044464 cell part C 0 0 0 0 0 184 857 115 21.47025 745.2174 -2.402 0.012 1 0090305 nucleic acid phosphodiester bond hydrolysis P 3 37 37 8.108109 100 3 40 39 7.5 102.5641 -2.503 0.012 0.997 0022613 ribonucleoprotein complex biogenesis P 0 0 0 0 0 1 27 25 3.703704 108 -2.513 0.012 0.997 0042254 ribosome biogenesis P 0 9 9 0 100 1 27 25 3.703704 108 -2.513 0.012 0.997 0019538 protein metabolic process P 2 4 4 50 100 38 220 103 17.27273 213.5922 -2.559 0.012 0.996 0032555 purine ribonucleotide binding F 0 0 0 0 0 59 316 292 18.67089 108.2192 -2.513 0.013 0.997 0006793 phosphorus metabolic process P 0 1 1 0 100 35 206 25 16.99029 824 -2.567 0.013 0.995 0032991 macromolecular complex C 0 0 0 0 0 22 143 56 15.38461 255.3571 -2.572 0.013 0.995 0009074 aromatic amino acid family catabolic process P 0 0 0 0 0 4 5 4 80 125 2.9 0.014 0.987 0046903 secretion P 1 1 1 100 100 13 28 22 46.42857 127.2727 2.734 0.014 0.99 0009306 protein secretion P 10 20 20 50 100 13 28 21 46.42857 133.3333 2.734 0.014 0.99 0032940 secretion by cell P 0 0 0 0 0 13 28 21 46.42857 133.3333 2.734 0.014 0.99 0080090 regulation of primary metabolic process P 0 0 0 0 0 89 289 270 30.79585 107.037 2.699 0.014 0.99 0016782 transferase activity, transferring sulfur-containing groups F 0 0 0 0 0 6 10 4 60 250 2.63 0.014 0.992 0022890 inorganic cation transmembrane transporter activity F 0 0 0 0 0 3 39 6 7.692307 650 -2.443 0.014 1 0009408 response to heat P 3 3 3 100 100 3 3 3 100 100 3.053 0.015 0.94 0051259 protein oligomerization P 1 1 1 100 100 3 3 3 100 100 3.053 0.015 0.94 0004176 ATP-dependent peptidase activity F 3 3 3 100 100 3 3 3 100 100 3.053 0.015 0.94 0009266 response to temperature stimulus P 0 0 0 0 0 3 3 3 100 100 3.053 0.015 0.94 0016151 nickel cation binding F 4 5 5 80 100 4 5 5 80 100 2.9 0.015 0.987 0009116 nucleoside metabolic process P 1 6 6 16.66667 100 7 65 7 10.76923 928.5714 -2.585 0.015 0.995 1901657 glycosyl compound metabolic process P 0 0 0 0 0 7 65 7 10.76923 928.5714 -2.585 0.015 0.995 0004386 helicase activity F 0 19 19 0 100 0 19 19 0 100 -2.482 0.016 1 0050801 ion homeostasis P 0 0 0 0 0 5 7 1 71.42857 700 2.904 0.017 0.973 0098771 inorganic ion homeostasis P 0 0 0 0 0 5 7 1 71.42857 700 2.904 0.017 0.973 0048878 chemical homeostasis P 0 0 0 0 0 5 7 1 71.42857 700 2.904 0.017 0.973 0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor F 0 1 1 0 100 0 15 2 0 750 -2.204 0.017 1 0016788 hydrolase activity, acting on ester bonds F 1 7 7 14.28571 100 12 87 9 13.7931 966.6667 -2.335 0.017 1 0098662 inorganic cation transmembrane transport P 0 0 0 0 0 2 32 22 6.25 145.4545 -2.401 0.017 1 0016746 transferase activity, transferring acyl groups F 5 36 36 13.88889 100 9 73 48 12.32877 152.0833 -2.429 0.017 1 0072525 pyridine-containing compound biosynthetic process P 0 0 0 0 0 8 16 7 50 228.5714 2.396 0.018 1 0022892 substrate-specific transporter activity F 0 0 0 0 0 14 99 16 14.14141 618.75 -2.415 0.018 1 0009163 nucleoside biosynthetic process P 0 0 0 0 0 3 39 3 7.692307 1300 -2.443 0.018 1 0042455 ribonucleoside biosynthetic process P 0 0 0 0 0 3 39 3 7.692307 1300 -2.443 0.018 1 1901659 glycosyl compound biosynthetic process P 0 0 0 0 0 3 39 3 7.692307 1300 -2.443 0.018 1 0044422 organelle part C 0 0 0 0 0 3 38 7 7.894737 542.8571 -2.382 0.019 1 0017076 purine nucleotide binding F 0 0 0 0 0 60 317 292 18.92744 108.5616 -2.404 0.019 1 0044446 intracellular organelle part C 0 0 0 0 0 0 18 7 0 257.1429 -2.416 0.019 1 0009119 ribonucleoside metabolic process P 0 0 0 0 0 7 62 3 11.29032 2066.667 -2.426 0.019 1 0008654 phospholipid biosynthetic process P 1 9 9 11.11111 100 1 26 18 3.846154 144.4444 -2.449 0.02 1 0036094 small molecule binding F 0 0 0 0 0 94 464 292 20.25862 158.9041 -2.269 0.021 1 0003677 DNA binding F 102 345 392 29.56522 88.0102 104 348 392 29.88506 88.77551 2.575 0.022 0.995 0006281 DNA repair P 3 36 36 8.333333 100 3 37 36 8.108109 102.7778 -2.319 0.022 1 0006974 cellular response to DNA damage stimulus P 2 24 24 8.333333 100 3 37 36 8.108109 102.7778 -2.319 0.022 1 0097367 carbohydrate derivative binding F 0 0 0 0 0 64 334 292 19.16168 114.3836 -2.37 0.022 1 0044270 cellular nitrogen compound catabolic process P 0 0 0 0 0 9 19 4 47.36842 475 2.344 0.023 1 1901265 nucleoside phosphate binding F 0 0 0 0 0 86 433 327 19.86143 132.4159 -2.387 0.023 1 0000166 nucleotide binding F 51 281 281 18.14947 100 86 433 327 19.86143 132.4159 -2.387 0.023 1 0006796 phosphate-containing compound metabolic process P 0 1 1 0 100 35 201 24 17.41294 837.5 -2.388 0.023 1 0030001 metal ion transport P 0 8 8 0 100 1 23 10 4.347826 230 -2.246 0.024 1 0032553 ribonucleotide binding F 0 0 0 0 0 64 332 292 19.27711 113.6986 -2.309 0.024 1 0044723 single-organism carbohydrate metabolic process P 0 0 0 0 0 4 45 7 8.888889 642.8571 -2.439 0.024 1 0044255 cellular lipid metabolic process P 0 0 0 0 0 7 61 7 11.47541 871.4286 -2.372 0.025 1 0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor F 0 18 18 0 100 5 50 22 10 227.2727 -2.388 0.025 1 0006461 protein complex assembly P 1 1 1 100 100 5 8 4 62.5 200 2.516 0.026 0.997 0070271 protein complex biogenesis P 0 0 0 0 0 5 8 4 62.5 200 2.516 0.026 0.997 0019720 Mo-molybdopterin cofactor metabolic process P 0 1 1 0 100 5 8 8 62.5 100 2.516 0.026 0.997 0006777 Mo-molybdopterin cofactor biosynthetic process P 5 8 8 62.5 100 5 8 8 62.5 100 2.516 0.026 0.997 0019693 ribose phosphate metabolic process P 0 0 0 0 0 10 74 3 13.51351 2466.667 -2.205 0.026 1 0030170 pyridoxal phosphate binding F 16 41 41 39.02439 100 16 41 41 39.02439 100 2.203 0.027 1 0051128 regulation of cellular component organization P 0 0 0 0 0 1 24 19 4.166667 126.3158 -2.315 0.027 1 0034660 ncRNA metabolic process P 0 0 0 0 0 8 64 25 12.5 256 -2.238 0.029 1 0015077 monovalent inorganic cation transmembrane transporter activity F 0 0 0 0 0 2 30 7 6.666667 428.5714 -2.271 0.029 1 0042597 periplasmic space C 10 26 26 38.46154 100 38 115 115 33.04348 100 2.217 0.03 1 0018193 peptidyl-amino acid modification P 0 1 1 0 100 0 15 7 0 214.2857 -2.204 0.03 1 0004518 nuclease activity F 2 24 24 8.333333 100 4 43 29 9.302325 148.2759 -2.319 0.03 1 0006396 RNA processing P 0 12 12 0 100 5 49 32 10.20408 153.125 -2.33 0.03 1 0072329 monocarboxylic acid catabolic process P 0 0 0 0 0 6 11 1 54.54546 1100 2.336 0.031 1 0016829 lyase activity F 38 99 100 38.38384 99 38 116 100 32.75862 116 2.154 0.031 1 0055085 transmembrane transport P 20 102 102 19.60784 100 28 167 104 16.76647 160.5769 -2.363 0.031 1 0009605 response to external stimulus P 0 0 0 0 0 1 22 8 4.545455 275 -2.174 0.032 1 1902578 single-organism localization P 0 0 0 0 0 51 271 22 18.81919 1231.818 -2.245 0.032 1 1903509 liposaccharide metabolic process P 0 0 0 0 0 0 16 7 0 228.5714 -2.277 0.032 1 0065007 biological regulation P 0 0 0 0 0 109 377 270 28.91247 139.6296 2.222 0.034 1 0006629 lipid metabolic process P 4 26 26 15.38461 100 9 68 33 13.23529 206.0606 -2.166 0.034 1 0004519 endonuclease activity F 0 14 14 0 100 1 22 14 4.545455 157.1429 -2.174 0.034 1 0044765 single-organism transport P 0 0 0 0 0 50 266 22 18.79699 1209.091 -2.23 0.034 1 0000287 magnesium ion binding F 8 65 65 12.30769 100 8 65 65 12.30769 100 -2.292 0.034 1 0006996 organelle organization P 0 0 0 0 0 4 39 1 10.25641 3900 -2.067 0.035 1 0044282 small molecule catabolic process P 0 0 0 0 0 13 31 1 41.93548 3100 2.292 0.036 1 0043565 sequence-specific DNA binding F 16 41 44 39.02439 93.18182 16 41 44 39.02439 93.18182 2.203 0.036 1 0003924 GTPase activity F 0 16 16 0 100 0 16 16 0 100 -2.277 0.036 1 0055065 metal ion homeostasis P 0 0 0 0 0 4 6 1 66.66666 600 2.416 0.037 1 0055080 cation homeostasis P 0 0 0 0 0 4 6 1 66.66666 600 2.416 0.037 1 0006091 generation of precursor metabolites and energy P 0 0 0 0 0 6 50 12 12 416.6667 -2.056 0.038 1 0055082 cellular chemical homeostasis P 0 0 0 0 0 4 6 1 66.66666 600 2.416 0.039 1 0006873 cellular ion homeostasis P 0 0 0 0 0 4 6 1 66.66666 600 2.416 0.039 1 0004300 enoyl-CoA hydratase activity F 4 6 6 66.66666 100 4 6 6 66.66666 100 2.416 0.04 1 0043605 cellular amide catabolic process P 0 0 0 0 0 3 4 1 75 400 2.36 0.04 1 0050136 NADH dehydrogenase (quinone) activity F 0 7 7 0 100 0 13 13 0 100 -2.051 0.04 1 0016836 hydro-lyase activity F 0 2 2 0 100 13 32 8 40.625 400 2.155 0.041 1 0046395 carboxylic acid catabolic process P 0 0 0 0 0 10 23 1 43.47826 2300 2.144 0.041 1 0016054 organic acid catabolic process P 0 0 0 0 0 10 23 1 43.47826 2300 2.144 0.041 1 0009141 nucleoside triphosphate metabolic process P 0 0 0 0 0 4 37 9 10.81081 411.1111 -1.934 0.041 1 0071840 cellular component organization or biogenesis P 0 0 0 0 0 21 127 1 16.53543 12700 -2.106 0.041 1 0005623 cell C 12 29 29 41.37931 100 196 885 144 22.14689 614.5833 -1.885 0.042 1 0008152 metabolic process P 145 614 614 23.61563 100 421 1810 648 23.25967 279.321 -1.956 0.042 1 0016787 hydrolase activity F 45 231 231 19.48052 100 86 420 321 20.47619 130.8411 -2.024 0.043 1 0051301 cell division P 3 33 33 9.090909 100 3 34 33 8.823529 103.0303 -2.124 0.043 1 0044248 cellular catabolic process P 0 0 0 0 0 20 54 1 37.03704 5400 2.191 0.044 1 0009259 ribonucleotide metabolic process P 0 0 0 0 0 10 70 3 14.28571 2333.333 -1.991 0.045 1 0042952 beta-ketoadipate pathway P 2 2 2 100 100 2 2 2 100 100 2.492 0.046 1 0006979 response to oxidative stress P 4 8 8 50 100 6 12 12 50 100 2.073 0.046 1 0005215 transporter activity F 21 81 81 25.92593 100 36 195 97 18.46154 201.0309 -1.995 0.046 1 0034470 ncRNA processing P 0 0 0 0 0 5 44 25 11.36364 176 -2.025 0.046 1 0051189 prosthetic group metabolic process P 0 0 0 0 0 5 9 8 55.55556 112.5 2.183 0.049 1 0032324 molybdopterin cofactor biosynthetic process P 1 2 2 50 100 5 9 9 55.55556 100 2.183 0.049 1 0043545 molybdopterin cofactor metabolic process P 0 0 0 0 0 5 9 8 55.55556 112.5 2.183 0.049 1 0034641 cellular nitrogen compound metabolic process P 0 0 0 0 0 155 720 282 21.52778 255.3192 -2.079 0.049 1 0055072 iron ion homeostasis P 1 1 1 100 100 3 4 4 75 100 2.36 0.05 1 0003858 3-hydroxybutyrate dehydrogenase activity F 2 2 2 100 100 2 2 2 100 100 2.492 0.051 1 0016747 transferase activity, transferring acyl groups other than amino-acyl groups F 0 18 18 0 100 6 51 20 11.76471 255 -2.116 0.051 1 0070283 radical SAM enzyme activity F 0 0 0 0 0 2 2 1 100 200 2.492 0.052 1 0030254 protein secretion by the type III secretion system P 3 4 4 75 100 3 4 4 75 100 2.36 0.052 1 0034654 nucleobase-containing compound biosynthetic process P 0 0 0 0 0 104 364 275 28.57143 132.3636 2.014 0.052 1 0009376 HslUV protease complex C 2 2 2 100 100 2 2 2 100 100 2.492 0.053 1 0031597 cytosolic proteasome complex C 0 0 0 0 0 2 2 2 100 100 2.492 0.053 1 0003992 N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity F 2 2 2 100 100 2 2 2 100 100 2.492 0.053 1 0000502 proteasome complex C 0 0 0 0 0 2 2 2 100 100 2.492 0.053 1 0098869 cellular oxidant detoxification P 6 13 13 46.15385 100 8 17 17 47.05882 100 2.186 0.053 1 0098754 detoxification P 0 0 0 0 0 8 17 17 47.05882 100 2.186 0.053 1 0016209 antioxidant activity F 4 9 9 44.44444 100 8 17 11 47.05882 154.5455 2.186 0.053 1 1990748 cellular detoxification P 0 0 0 0 0 8 17 17 47.05882 100 2.186 0.053 1 0015992 proton transport P 1 11 11 9.090909 100 2 25 23 8 108.6957 -1.915 0.053 1 0006818 hydrogen transport P 0 0 0 0 0 2 25 23 8 108.6957 -1.915 0.053 1 0044710 single-organism metabolic process P 0 0 0 0 0 164 757 359 21.66446 210.8635 -2.049 0.053 1 0008094 DNA-dependent ATPase activity F 0 2 2 0 100 0 14 10 0 140 -2.129 0.053 1 0044391 ribosomal subunit C 0 0 0 0 0 0 14 7 0 200 -2.129 0.053 1 0015419 sulfate transmembrane-transporting ATPase activity F 2 2 2 100 100 2 2 2 100 100 2.492 0.054 1 0046218 indolalkylamine catabolic process P 0 0 0 0 0 3 4 4 75 100 2.36 0.054 1 0070189 kynurenine metabolic process P 0 0 0 0 0 3 4 1 75 400 2.36 0.054 1 0006569 tryptophan catabolic process P 3 3 3 100 100 3 4 4 75 100 2.36 0.054 1 0009310 amine catabolic process P 0 0 0 0 0 3 4 4 75 100 2.36 0.054 1 0042402 cellular biogenic amine catabolic process P 0 0 0 0 0 3 4 4 75 100 2.36 0.054 1 0042436 indole-containing compound catabolic process P 0 0 0 0 0 3 4 4 75 100 2.36 0.054 1 0009199 ribonucleoside triphosphate metabolic process P 0 0 0 0 0 3 32 9 9.375 355.5555 -1.987 0.054 1 0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor F 2 2 2 100 100 3 4 2 75 200 2.36 0.055 1 0007049 cell cycle P 3 30 30 10 100 3 32 30 9.375 106.6667 -1.987 0.055 1 0032561 guanyl ribonucleotide binding F 0 0 0 0 0 2 26 25 7.692307 104 -1.99 0.056 1 0019001 guanyl nucleotide binding F 0 0 0 0 0 2 26 25 7.692307 104 -1.99 0.056 1 0016817 hydrolase activity, acting on acid anhydrides F 0 0 0 0 0 32 177 114 18.0791 155.2632 -2.016 0.056 1 0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides F 0 3 3 0 100 32 177 114 18.0791 155.2632 -2.016 0.056 1 0044179 hemolysis in other organism P 3 4 4 75 100 3 4 4 75 100 2.36 0.057 1 0035821 modification of morphology or physiology of other organism P 0 0 0 0 0 3 4 4 75 100 2.36 0.057 1 0051715 cytolysis in other organism P 0 0 0 0 0 3 4 4 75 100 2.36 0.057 1 0031640 killing of cells of other organism P 0 0 0 0 0 3 4 4 75 100 2.36 0.057 1 0001906 cell killing P 0 0 0 0 0 3 4 4 75 100 2.36 0.057 1 0044364 disruption of cells of other organism P 0 0 0 0 0 3 4 4 75 100 2.36 0.057 1 0046390 ribose phosphate biosynthetic process P 0 0 0 0 0 6 48 3 12.5 1600 -1.932 0.057 1 0071103 DNA conformation change P 0 0 0 0 0 1 19 3 5.263158 633.3333 -1.946 0.057 1 0032989 cellular component morphogenesis P 0 0 0 0 0 1 20 21 5 95.2381 -2.025 0.057 1 0000902 cell morphogenesis P 0 3 3 0 100 1 20 21 5 95.2381 -2.025 0.057 1 0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides F 1 1 1 100 100 2 2 1 100 200 2.492 0.058 1 0008199 ferric iron binding F 3 4 4 75 100 3 4 4 75 100 2.36 0.058 1 0005976 polysaccharide metabolic process P 0 0 0 0 0 0 14 7 0 200 -2.129 0.058 1 0009062 fatty acid catabolic process P 0 0 0 0 0 2 2 1 100 200 2.492 0.059 1 0051087 chaperone binding F 2 2 2 100 100 2 2 2 100 100 2.492 0.059 1 0009107 lipoate biosynthetic process P 2 2 2 100 100 2 2 2 100 100 2.492 0.06 1 0009106 lipoate metabolic process P 0 0 0 0 0 2 2 2 100 100 2.492 0.06 1 0016835 carbon-oxygen lyase activity F 0 1 1 0 100 15 40 9 37.5 444.4445 1.95 0.06 1 0005525 GTP binding F 2 25 25 8 100 2 25 25 8 100 -1.915 0.06 1 0016072 rRNA metabolic process P 0 0 0 0 0 1 19 19 5.263158 100 -1.946 0.06 1 0006364 rRNA processing P 1 18 18 5.555555 100 1 19 19 5.263158 100 -1.946 0.06 1 0004115 3’,5’-cyclic-AMP phosphodiesterase activity F 2 2 2 100 100 2 2 2 100 100 2.492 0.061 1 0004114 3’,5’-cyclic-nucleotide phosphodiesterase activity F 0 0 0 0 0 2 2 2 100 100 2.492 0.061 1 0004112 cyclic-nucleotide phosphodiesterase activity F 0 0 0 0 0 2 2 2 100 100 2.492 0.061 1 0004419 hydroxymethylglutaryl-CoA lyase activity F 2 2 2 100 100 2 2 2 100 100 2.492 0.063 1 0043420 anthranilate metabolic process P 2 2 2 100 100 2 2 2 100 100 2.492 0.064 1 0000107 imidazoleglycerol-phosphate synthase activity F 2 2 2 100 100 2 2 2 100 100 2.492 0.065 1 0051540 metal cluster binding F 0 0 0 0 0 23 67 64 34.32836 104.6875 1.924 0.065 1 0051536 iron-sulfur cluster binding F 20 61 61 32.78688 100 23 67 64 34.32836 104.6875 1.924 0.065 1 0015002 heme-copper terminal oxidase activity F 0 3 3 0 100 0 11 9 0 122.2222 -1.886 0.065 1 0051262 protein tetramerization P 1 1 1 100 100 2 2 2 100 100 2.492 0.066 1 0042558 pteridine-containing compound metabolic process P 0 2 2 0 100 1 19 3 5.263158 633.3333 -1.946 0.066 1 0051276 chromosome organization P 0 1 1 0 100 1 20 1 5 2000 -2.025 0.066 1 0061731 ribonucleoside-diphosphate reductase activity F 0 0 0 0 0 2 2 2 100 100 2.492 0.067 1 0042618 poly-hydroxybutyrate metabolic process P 0 0 0 0 0 2 2 2 100 100 2.492 0.067 1 0016822 hydrolase activity, acting on acid carbon-carbon bonds F 0 0 0 0 0 2 2 1 100 200 2.492 0.067 1 0042619 poly-hydroxybutyrate biosynthetic process P 2 2 2 100 100 2 2 2 100 100 2.492 0.067 1 0016823 hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances F 0 0 0 0 0 2 2 1 100 200 2.492 0.067 1 0016728 oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor F 0 0 0 0 0 2 2 2 100 100 2.492 0.067 1 0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor F 2 2 2 100 100 2 2 2 100 100 2.492 0.067 1 1901441 poly(hydroxyalkanoate) biosynthetic process P 0 0 0 0 0 2 2 2 100 100 2.492 0.067 1 1901440 poly(hydroxyalkanoate) metabolic process P 0 0 0 0 0 2 2 2 100 100 2.492 0.067 1 0016462 pyrophosphatase activity F 0 2 2 0 100 32 176 113 18.18182 155.7522 -1.977 0.067 1 0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity F 2 2 2 100 100 2 2 2 100 100 2.492 0.068 1 0051649 establishment of localization in cell P 0 0 0 0 0 17 47 21 36.17021 223.8095 1.902 0.068 1 0050794 regulation of cellular process P 0 0 0 0 0 101 358 270 28.21229 132.5926 1.824 0.069 1 0032559 adenyl ribonucleotide binding F 0 0 0 0 0 58 292 292 19.86301 100 -1.9 0.069 1 0005524 ATP binding F 58 292 292 19.86301 100 58 292 292 19.86301 100 -1.9 0.069 1 0072521 purine-containing compound metabolic process P 0 0 0 0 0 9 63 20 14.28571 315 -1.886 0.07 1 0009161 ribonucleoside monophosphate metabolic process P 0 0 0 0 0 8 57 4 14.03509 1425 -1.836 0.071 1 0040011 locomotion P 0 0 0 0 0 3 30 14 10 214.2857 -1.843 0.071 1 0009144 purine nucleoside triphosphate metabolic process P 0 0 0 0 0 3 30 9 10 333.3333 -1.843 0.073 1 0009205 purine ribonucleoside triphosphate metabolic process P 0 0 0 0 0 3 30 9 10 333.3333 -1.843 0.073 1 0046128 purine ribonucleoside metabolic process P 0 0 0 0 0 6 47 3 12.76596 1566.667 -1.869 0.073 1 0042278 purine nucleoside metabolic process P 0 0 0 0 0 6 47 3 12.76596 1566.667 -1.869 0.073 1 0009260 ribonucleotide biosynthetic process P 0 0 0 0 0 6 47 3 12.76596 1566.667 -1.869 0.074 1 0050789 regulation of biological process P 0 0 0 0 0 103 367 270 28.0654 135.9259 1.78 0.075 1 0009123 nucleoside monophosphate metabolic process P 0 0 0 0 0 9 60 3 15 2000 -1.709 0.075 1 0009308 amine metabolic process P 0 0 0 0 0 5 10 8 50 125 1.892 0.078 1 0044106 cellular amine metabolic process P 0 0 0 0 0 5 10 8 50 125 1.892 0.078 1 0006576 cellular biogenic amine metabolic process P 0 0 0 0 0 5 10 8 50 125 1.892 0.078 1 0008081 phosphoric diester hydrolase activity F 1 2 2 50 100 3 5 4 60 125 1.858 0.078 1 1902600 hydrogen ion transmembrane transport P 2 14 14 14.28571 100 2 24 22 8.333333 109.0909 -1.838 0.078 1 0030145 manganese ion binding F 0 11 11 0 100 0 11 11 0 100 -1.886 0.079 1 0009311 oligosaccharide metabolic process P 0 0 0 0 0 0 12 9 0 133.3333 -1.97 0.08 1 0009312 oligosaccharide biosynthetic process P 0 0 0 0 0 0 12 9 0 133.3333 -1.97 0.08 1 0004540 ribonuclease activity F 0 3 3 0 100 0 11 6 0 183.3333 -1.886 0.082 1 0090501 RNA phosphodiester bond hydrolysis P 0 6 6 0 100 0 11 9 0 122.2222 -1.886 0.082 1 0000271 polysaccharide biosynthetic process P 0 4 4 0 100 0 12 10 0 120 -1.97 0.082 1 1901576 organic substance biosynthetic process P 0 0 0 0 0 158 718 277 22.00557 259.2058 -1.726 0.084 1 0006163 purine nucleotide metabolic process P 1 2 2 50 100 9 61 20 14.7541 305 -1.769 0.084 1 0030288 outer membrane-bounded periplasmic space C 32 99 99 32.32323 100 32 99 99 32.32323 100 1.88 0.085 1 0050793 regulation of developmental process P 0 0 0 0 0 1 18 19 5.555555 94.73684 -1.865 0.085 1 0022603 regulation of anatomical structure morphogenesis P 0 0 0 0 0 1 18 19 5.555555 94.73684 -1.865 0.085 1 0022604 regulation of cell morphogenesis P 0 0 0 0 0 1 18 19 5.555555 94.73684 -1.865 0.085 1 0008360 regulation of cell shape P 1 18 19 5.555555 94.73684 1 18 19 5.555555 94.73684 -1.865 0.085 1 0030163 protein catabolic process P 3 5 5 60 100 3 5 5 60 100 1.858 0.086 1 0032508 DNA duplex unwinding P 0 10 10 0 100 0 11 11 0 100 -1.886 0.087 1 0003678 DNA helicase activity F 0 2 2 0 100 0 11 10 0 110 -1.886 0.087 1 0032392 DNA geometric change P 0 0 0 0 0 0 11 11 0 100 -1.886 0.087 1 0098660 inorganic ion transmembrane transport P 0 0 0 0 0 5 40 22 12.5 181.8182 -1.761 0.088 1 0008272 sulfate transport P 3 5 5 60 100 3 5 5 60 100 1.858 0.089 1 1902358 sulfate transmembrane transport P 3 5 5 60 100 3 5 5 60 100 1.858 0.089 1 0015116 sulfate transmembrane transporter activity F 1 3 3 33.33333 100 3 5 4 60 125 1.858 0.089 1 1901682 sulfur compound transmembrane transporter activity F 0 0 0 0 0 3 5 4 60 125 1.858 0.089 1 0030554 adenyl nucleotide binding F 0 0 0 0 0 59 293 292 20.13652 100.3425 -1.788 0.09 1 0017111 nucleoside-triphosphatase activity F 0 1 1 0 100 31 168 111 18.45238 151.3513 -1.844 0.09 1 0015980 energy derivation by oxidation of organic compounds P 0 0 0 0 0 4 34 9 11.76471 377.7778 -1.722 0.091 1 0000049 tRNA binding F 1 17 17 5.882353 100 1 17 17 5.882353 100 -1.781 0.091 1 0016833 oxo-acid-lyase activity F 0 1 1 0 100 4 8 3 50 266.6667 1.691 0.093 1 0046873 metal ion transmembrane transporter activity F 0 3 3 0 100 1 17 6 5.882353 283.3333 -1.781 0.093 1 0015075 ion transmembrane transporter activity F 0 1 1 0 100 11 71 11 15.49296 645.4545 -1.765 0.094 1 0006259 DNA metabolic process P 0 8 8 0 100 14 85 42 16.47059 202.381 -1.723 0.095 1 0030003 cellular cation homeostasis P 0 0 0 0 0 3 5 1 60 500 1.858 0.097 1 0036361 racemase activity, acting on amino acids and derivatives F 1 2 2 50 100 3 5 3 60 166.6667 1.858 0.097 1 0006875 cellular metal ion homeostasis P 0 0 0 0 0 3 5 1 60 500 1.858 0.097 1 0016855 racemase and epimerase activity, acting on amino acids and derivatives F 0 1 1 0 100 3 5 3 60 166.6667 1.858 0.097 1 0019835 cytolysis P 3 5 5 60 100 3 5 5 60 100 1.858 0.097 1 0006807 nitrogen compound metabolic process P 6 12 12 50 100 189 848 294 22.28773 288.4354 -1.71 0.098 1 0043412 macromolecule modification P 0 2 2 0 100 14 86 18 16.27907 477.7778 -1.776 0.098 1 0044445 cytosolic part C 0 0 0 0 0 3 5 2 60 250 1.858 0.099 1 0042451 purine nucleoside biosynthetic process P 0 0 0 0 0 2 24 3 8.333333 800 -1.838 0.099 1 0046129 purine ribonucleoside biosynthetic process P 0 0 0 0 0 2 24 3 8.333333 800 -1.838 0.099 1 0055076 transition metal ion homeostasis P 0 0 0 0 0 3 5 4 60 125 1.858 0.1 1 0009986 cell surface C 3 5 5 60 100 3 5 5 60 100 1.858 0.1 1 0022900 electron transport chain P 0 5 5 0 100 1 17 11 5.882353 154.5455 -1.781 0.1 1 0016684 oxidoreductase activity, acting on peroxide as acceptor F 0 0 0 0 0 4 8 6 50 133.3333 1.691 0.102 1 0046034 ATP metabolic process P 1 3 3 33.33333 100 3 28 9 10.71429 311.1111 -1.691 0.102 1 0016311 dephosphorylation P 1 11 11 9.090909 100 1 17 13 5.882353 130.7692 -1.781 0.102 1 1901575 organic substance catabolic process P 0 0 0 0 0 23 70 4 32.85714 1750 1.677 0.103 1 0016667 oxidoreductase activity, acting on a sulfur group of donors F 1 1 1 100 100 8 19 5 42.10526 380 1.808 0.105 1 0000097 sulfur amino acid biosynthetic process P 0 0 0 0 0 0 9 8 0 112.5 -1.705 0.109 1 1901565 organonitrogen compound catabolic process P 0 0 0 0 0 10 26 2 38.46154 1300 1.682 0.11 1 0044249 cellular biosynthetic process P 0 1 1 0 100 155 700 276 22.14286 253.6232 -1.597 0.11 1 0051641 cellular localization P 0 0 0 0 0 18 52 21 34.61538 247.619 1.739 0.111 1 0009150 purine ribonucleotide metabolic process P 0 0 0 0 0 9 58 3 15.51724 1933.333 -1.587 0.112 1 0004129 cytochrome-c oxidase activity F 0 9 9 0 100 0 9 9 0 100 -1.705 0.112 1 0016676 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor F 0 0 0 0 0 0 9 9 0 100 -1.705 0.112 1 0016675 oxidoreductase activity, acting on a heme group of donors F 0 0 0 0 0 0 9 9 0 100 -1.705 0.112 1 0032502 developmental process P 0 0 0 0 0 2 22 19 9.090909 115.7895 -1.676 0.114 1 0048856 anatomical structure development P 0 0 0 0 0 2 22 19 9.090909 115.7895 -1.676 0.114 1 0048869 cellular developmental process P 0 0 0 0 0 2 22 21 9.090909 104.7619 -1.676 0.114 1 0009653 anatomical structure morphogenesis P 0 0 0 0 0 2 22 19 9.090909 115.7895 -1.676 0.114 1 0044767 single-organism developmental process P 0 0 0 0 0 2 22 21 9.090909 104.7619 -1.676 0.114 1 0034637 cellular carbohydrate biosynthetic process P 0 0 0 0 0 0 9 6 0 150 -1.705 0.115 1 1901362 organic cyclic compound biosynthetic process P 0 0 0 0 0 126 459 275 27.45098 166.9091 1.695 0.116 1 0034220 ion transmembrane transport P 1 5 5 20 100 9 59 32 15.25424 184.375 -1.648 0.116 1 0015078 hydrogen ion transmembrane transporter activity F 0 3 3 0 100 2 22 7 9.090909 314.2857 -1.676 0.116 1 0018130 heterocycle biosynthetic process P 0 0 0 0 0 123 449 275 27.39421 163.2727 1.642 0.12 1 0009156 ribonucleoside monophosphate biosynthetic process P 0 1 1 0 100 5 37 4 13.51351 925 -1.548 0.121 1 0044260 cellular macromolecule metabolic process P 0 0 0 0 0 131 597 275 21.94305 217.0909 -1.567 0.122 1 0004312 fatty acid synthase activity F 0 0 0 0 0 0 9 2 0 450 -1.705 0.122 1 0019438 aromatic compound biosynthetic process P 0 0 0 0 0 118 429 275 27.50583 156 1.656 0.124 1 0051246 regulation of protein metabolic process P 0 0 0 0 0 1 15 5 6.666667 300 -1.601 0.124 1 0006399 tRNA metabolic process P 0 0 0 0 0 7 48 25 14.58333 192 -1.593 0.125 1 0009245 lipid A biosynthetic process P 0 9 9 0 100 0 9 9 0 100 -1.705 0.125 1 0046493 lipid A metabolic process P 0 0 0 0 0 0 9 9 0 100 -1.705 0.125 1 1901269 lipooligosaccharide metabolic process P 0 0 0 0 0 0 9 9 0 100 -1.705 0.125 1 0009247 glycolipid biosynthetic process P 0 0 0 0 0 0 9 9 0 100 -1.705 0.125 1 1901271 lipooligosaccharide biosynthetic process P 0 0 0 0 0 0 9 9 0 100 -1.705 0.125 1 0046467 membrane lipid biosynthetic process P 0 0 0 0 0 0 9 9 0 100 -1.705 0.125 1 0006664 glycolipid metabolic process P 0 0 0 0 0 0 9 9 0 100 -1.705 0.125 1 0006643 membrane lipid metabolic process P 0 0 0 0 0 0 9 9 0 100 -1.705 0.125 1 0044712 single-organism catabolic process P 0 0 0 0 0 17 51 1 33.33333 5100 1.506 0.126 1 0022884 macromolecule transmembrane transporter activity F 0 0 0 0 0 0 9 7 0 128.5714 -1.705 0.126 1 0006720 isoprenoid metabolic process P 0 0 0 0 0 0 10 10 0 100 -1.798 0.129 1 0008299 isoprenoid biosynthetic process P 0 9 9 0 100 0 10 10 0 100 -1.798 0.129 1 0009877 nodulation P 2 3 3 66.66666 100 2 3 3 66.66666 100 1.707 0.132 1 0044403 symbiosis, encompassing mutualism through parasitism P 0 0 0 0 0 2 3 3 66.66666 100 1.707 0.132 1 0044419 interspecies interaction between organisms P 0 0 0 0 0 2 3 3 66.66666 100 1.707 0.132 1 0009056 catabolic process P 0 0 0 0 0 25 78 1 32.05128 7800 1.605 0.132 1 0044264 cellular polysaccharide metabolic process P 0 0 0 0 0 0 10 7 0 142.8571 -1.798 0.132 1 0050896 response to stimulus P 0 0 0 0 0 43 145 21 29.65517 690.4762 1.526 0.133 1 0070035 purine NTP-dependent helicase activity F 0 0 0 0 0 0 10 8 0 125 -1.798 0.133 1 0019682 glyceraldehyde-3-phosphate metabolic process P 0 0 0 0 0 0 10 4 0 250 -1.798 0.133 1 0008026 ATP-dependent helicase activity F 0 2 2 0 100 0 10 8 0 125 -1.798 0.133 1 0008137 NADH dehydrogenase (ubiquinone) activity F 0 10 10 0 100 0 10 10 0 100 -1.798 0.134 1 0061077 chaperone-mediated protein folding P 2 2 2 100 100 2 3 3 66.66666 100 1.707 0.135 1 0009166 nucleotide catabolic process P 0 0 0 0 0 2 3 2 66.66666 150 1.707 0.136 1 0044257 cellular protein catabolic process P 0 0 0 0 0 2 3 2 66.66666 150 1.707 0.138 1 0051603 proteolysis involved in cellular protein catabolic process P 1 1 1 100 100 2 3 2 66.66666 150 1.707 0.138 1 0043414 macromolecule methylation P 0 0 0 0 0 2 22 7 9.090909 314.2857 -1.676 0.139 1 0005694 chromosome C 0 6 6 0 100 0 10 10 0 100 -1.798 0.142 1 0072522 purine-containing compound biosynthetic process P 0 0 0 0 0 5 38 18 13.1579 211.1111 -1.621 0.143 1 0006164 purine nucleotide biosynthetic process P 2 17 17 11.76471 100 5 37 18 13.51351 205.5556 -1.548 0.144 1 0044262 cellular carbohydrate metabolic process P 0 0 0 0 0 1 16 7 6.25 228.5714 -1.693 0.145 1 0009072 aromatic amino acid family metabolic process P 1 3 3 33.33333 100 9 23 16 39.13044 143.75 1.657 0.147 1 0022402 cell cycle process P 0 0 0 0 0 1 16 9 6.25 177.7778 -1.693 0.147 1 0009636 response to toxic substance P 1 4 4 25 100 9 23 21 39.13044 109.5238 1.657 0.148 1 0046496 nicotinamide nucleotide metabolic process P 1 1 1 100 100 9 24 13 37.5 184.6154 1.506 0.148 1 0019362 pyridine nucleotide metabolic process P 0 0 0 0 0 9 24 13 37.5 184.6154 1.506 0.148 1 0006760 folic acid-containing compound metabolic process P 0 1 1 0 100 1 16 11 6.25 145.4545 -1.693 0.149 1 0044242 cellular lipid catabolic process P 0 0 0 0 0 2 3 1 66.66666 300 1.707 0.15 1 0006523 alanine biosynthetic process P 1 1 1 100 100 2 3 3 66.66666 100 1.707 0.151 1 0009078 pyruvate family amino acid metabolic process P 0 0 0 0 0 2 3 3 66.66666 100 1.707 0.151 1 0006522 alanine metabolic process P 1 2 2 50 100 2 3 3 66.66666 100 1.707 0.151 1 0009079 pyruvate family amino acid biosynthetic process P 0 0 0 0 0 2 3 3 66.66666 100 1.707 0.151 1 0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor F 2 5 5 40 100 3 6 6 50 100 1.464 0.151 1 0045333 cellular respiration P 1 1 1 100 100 4 32 9 12.5 355.5555 -1.573 0.151 1 0016791 phosphatase activity F 0 3 3 0 100 1 15 4 6.666667 375 -1.601 0.152 1 0016301 kinase activity F 10 59 59 16.94915 100 10 60 59 16.66667 101.6949 -1.405 0.155 1 0006879 cellular iron ion homeostasis P 2 3 3 66.66666 100 2 3 3 66.66666 100 1.707 0.156 1 0047661 amino-acid racemase activity F 0 0 0 0 0 2 3 1 66.66666 300 1.707 0.157 1 0030313 cell envelope C 0 0 0 0 0 40 134 99 29.85075 135.3535 1.518 0.158 1 0031975 envelope C 0 0 0 0 0 40 134 99 29.85075 135.3535 1.518 0.158 1 0044462 external encapsulating structure part C 0 0 0 0 0 40 134 99 29.85075 135.3535 1.518 0.158 1 0030312 external encapsulating structure C 0 0 0 0 0 40 134 99 29.85075 135.3535 1.518 0.158 1 0009167 purine ribonucleoside monophosphate metabolic process P 0 0 0 0 0 7 47 3 14.89362 1566.667 -1.526 0.159 1 0009126 purine nucleoside monophosphate metabolic process P 0 0 0 0 0 7 47 3 14.89362 1566.667 -1.526 0.159 1 0051253 negative regulation of RNA metabolic process P 0 0 0 0 0 2 3 3 66.66666 100 1.707 0.16 1 1903507 negative regulation of nucleic acid-templated transcription P 0 0 0 0 0 2 3 3 66.66666 100 1.707 0.16 1 0045892 negative regulation of transcription, DNA-templated P 2 3 3 66.66666 100 2 3 3 66.66666 100 1.707 0.16 1 1902679 negative regulation of RNA biosynthetic process P 0 0 0 0 0 2 3 3 66.66666 100 1.707 0.16 1 0051920 peroxiredoxin activity F 3 6 6 50 100 3 6 6 50 100 1.464 0.16 1 0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen F 0 0 0 0 0 3 6 3 50 200 1.464 0.161 1 0004364 glutathione transferase activity F 2 3 3 66.66666 100 2 3 3 66.66666 100 1.707 0.162 1 0019441 tryptophan catabolic process to kynurenine P 2 3 3 66.66666 100 2 3 3 66.66666 100 1.707 0.164 1 0016651 oxidoreductase activity, acting on NAD(P)H F 0 8 8 0 100 3 26 12 11.53846 216.6667 -1.531 0.164 1 0010035 response to inorganic substance P 0 0 0 0 0 3 6 4 50 150 1.464 0.166 1 0043225 anion transmembrane-transporting ATPase activity F 0 0 0 0 0 3 6 3 50 200 1.464 0.168 1 0008863 formate dehydrogenase (NAD+) activity F 2 3 3 66.66666 100 2 3 3 66.66666 100 1.707 0.169 1 0042221 response to chemical P 0 0 0 0 0 15 45 21 33.33333 214.2857 1.413 0.169 1 0019752 carboxylic acid metabolic process P 1 4 4 25 100 50 244 83 20.4918 293.9759 -1.479 0.172 1 0006090 pyruvate metabolic process P 0 2 2 0 100 2 20 13 10 153.8462 -1.502 0.173 1 0044281 small molecule metabolic process P 0 0 0 0 0 78 367 84 21.25341 436.9048 -1.496 0.174 1 0065003 macromolecular complex assembly P 0 0 0 0 0 5 11 4 45.45454 275 1.633 0.175 1 0016043 cellular component organization P 0 0 0 0 0 19 102 1 18.62745 10200 -1.376 0.175 1 0044283 small molecule biosynthetic process P 0 0 0 0 0 32 163 69 19.6319 236.2319 -1.453 0.177 1 0016070 RNA metabolic process P 0 1 1 0 100 97 357 276 27.17087 129.3478 1.328 0.181 1 0019829 cation-transporting ATPase activity F 0 2 2 0 100 1 13 6 7.692307 216.6667 -1.403 0.186 1 0022411 cellular component disassembly P 0 0 0 0 0 0 7 5 0 140 -1.503 0.187 1 0043241 protein complex disassembly P 0 0 0 0 0 0 7 5 0 140 -1.503 0.187 1 0032984 macromolecular complex disassembly P 0 0 0 0 0 0 7 5 0 140 -1.503 0.187 1 0009152 purine ribonucleotide biosynthetic process P 1 2 2 50 100 5 35 3 14.28571 1166.667 -1.398 0.188 1 0006082 organic acid metabolic process P 0 1 1 0 100 51 248 84 20.56452 295.2381 -1.464 0.189 1 0042995 cell projection C 0 0 0 0 0 4 30 4 13.33333 750 -1.415 0.19 1 0051537 2 iron, 2 sulfur cluster binding F 11 31 31 35.48387 100 11 31 31 35.48387 100 1.45 0.191 1 0032268 regulation of cellular protein metabolic process P 0 0 0 0 0 1 14 5 7.142857 280 -1.505 0.191 1 0006721 terpenoid metabolic process P 0 0 0 0 0 0 8 8 0 100 -1.607 0.191 1 0016114 terpenoid biosynthetic process P 0 7 7 0 100 0 8 8 0 100 -1.607 0.191 1 0006417 regulation of translation P 0 4 4 0 100 1 13 5 7.692307 260 -1.403 0.192 1 0010608 posttranscriptional regulation of gene expression P 0 0 0 0 0 1 13 5 7.692307 260 -1.403 0.192 1 0034248 regulation of cellular amide metabolic process P 0 0 0 0 0 1 13 5 7.692307 260 -1.403 0.192 1 0016763 transferase activity, transferring pentosyl groups F 2 2 3 100 66.66666 5 12 4 41.66667 300 1.399 0.193 1 0015935 small ribosomal subunit C 0 7 7 0 100 0 7 7 0 100 -1.503 0.195 1 0030976 thiamine pyrophosphate binding F 5 12 12 41.66667 100 5 12 12 41.66667 100 1.399 0.196 1 0009124 nucleoside monophosphate biosynthetic process P 0 0 0 0 0 6 40 3 15 1333.333 -1.39 0.196 1 0016682 oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor F 0 3 3 0 100 0 7 7 0 100 -1.503 0.196 1 0042777 plasma membrane ATP synthesis coupled proton transport P 0 7 7 0 100 0 7 7 0 100 -1.503 0.196 1 0046933 proton-transporting ATP synthase activity, rotational mechanism F 0 7 7 0 100 0 7 7 0 100 -1.503 0.196 1 0070566 adenylyltransferase activity F 0 0 0 0 0 0 7 1 0 700 -1.503 0.197 1 0003954 NADH dehydrogenase activity F 1 1 1 100 100 1 14 14 7.142857 100 -1.505 0.197 1 0043170 macromolecule metabolic process P 0 0 0 0 0 150 668 277 22.45509 241.1552 -1.33 0.198 1 0046148 pigment biosynthetic process P 0 0 0 0 0 1 13 7 7.692307 185.7143 -1.403 0.198 1 0009066 aspartate family amino acid metabolic process P 0 0 0 0 0 2 19 8 10.52632 237.5 -1.41 0.198 1 1901615 organic hydroxy compound metabolic process P 0 0 0 0 0 2 19 2 10.52632 950 -1.41 0.198 1 0009103 lipopolysaccharide biosynthetic process P 0 6 6 0 100 0 7 6 0 116.6667 -1.503 0.2 1 0072330 monocarboxylic acid biosynthetic process P 0 0 0 0 0 4 29 5 13.7931 580 -1.333 0.201 1 0016679 oxidoreductase activity, acting on diphenols and related substances as donors F 0 1 1 0 100 0 8 8 0 100 -1.607 0.202 1 0008171 O-methyltransferase activity F 0 0 0 0 0 0 7 3 0 233.3333 -1.503 0.203 1 0006817 phosphate ion transport P 0 5 5 0 100 0 7 6 0 116.6667 -1.503 0.203 1 0042440 pigment metabolic process P 0 0 0 0 0 1 14 8 7.142857 175 -1.505 0.204 1 0006555 methionine metabolic process P 0 1 1 0 100 0 8 8 0 100 -1.607 0.204 1 0009086 methionine biosynthetic process P 0 8 8 0 100 0 8 8 0 100 -1.607 0.204 1 0070469 respiratory chain C 0 6 6 0 100 0 7 7 0 100 -1.503 0.205 1 0033692 cellular polysaccharide biosynthetic process P 0 0 0 0 0 0 8 6 0 133.3333 -1.607 0.205 1 0048038 quinone binding F 0 8 8 0 100 0 8 8 0 100 -1.607 0.206 1 0008653 lipopolysaccharide metabolic process P 0 1 1 0 100 0 8 7 0 114.2857 -1.607 0.206 1 0042559 pteridine-containing compound biosynthetic process P 0 0 0 0 0 1 13 1 7.692307 1300 -1.403 0.207 1 0015934 large ribosomal subunit C 0 7 7 0 100 0 7 7 0 100 -1.503 0.209 1 0043436 oxoacid metabolic process P 0 0 0 0 0 51 246 83 20.73171 296.3855 -1.394 0.21 1 0016645 oxidoreductase activity, acting on the CH-NH group of donors F 0 0 0 0 0 1 13 2 7.692307 650 -1.403 0.21 1 0006119 oxidative phosphorylation P 0 1 1 0 100 0 7 7 0 100 -1.503 0.21 1 0004003 ATP-dependent DNA helicase activity F 0 8 8 0 100 0 8 8 0 100 -1.607 0.211 1 0016881 acid-amino acid ligase activity F 0 2 2 0 100 1 13 4 7.692307 325 -1.403 0.212 1 0008320 protein transmembrane transporter activity F 0 3 3 0 100 0 7 7 0 100 -1.503 0.212 1 0009058 biosynthetic process P 10 43 43 23.25581 100 168 741 312 22.67206 237.5 -1.265 0.213 1 0016979 lipoate-protein ligase activity F 0 0 0 0 0 1 1 1 100 100 1.762 0.214 1 0016992 lipoate synthase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.214 1 0015031 protein transport P 7 30 30 23.33333 100 18 56 43 32.14286 130.2326 1.37 0.214 1 0006813 potassium ion transport P 0 7 7 0 100 0 7 7 0 100 -1.503 0.214 1 0004177 aminopeptidase activity F 0 7 7 0 100 0 7 7 0 100 -1.503 0.214 1 0015986 ATP synthesis coupled proton transport P 0 8 8 0 100 0 8 8 0 100 -1.607 0.214 1 0016469 proton-transporting two-sector ATPase complex C 0 0 0 0 0 0 8 5 0 160 -1.607 0.214 1 0015985 energy coupled proton transport, down electrochemical gradient P 0 0 0 0 0 0 8 8 0 100 -1.607 0.214 1 0045259 proton-transporting ATP synthase complex C 0 0 0 0 0 0 8 5 0 160 -1.607 0.214 1 0038023 signaling receptor activity F 0 0 0 0 0 3 23 18 13.04348 127.7778 -1.27 0.215 1 0009432 SOS response P 0 8 8 0 100 0 8 8 0 100 -1.607 0.215 1 0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines F 0 0 0 0 0 0 8 1 0 800 -1.607 0.215 1 0071496 cellular response to external stimulus P 0 0 0 0 0 0 8 8 0 100 -1.607 0.215 1 0009991 response to extracellular stimulus P 0 0 0 0 0 0 8 8 0 100 -1.607 0.215 1 0031668 cellular response to extracellular stimulus P 0 0 0 0 0 0 8 8 0 100 -1.607 0.215 1 0048519 negative regulation of biological process P 0 0 0 0 0 4 9 1 44.44444 900 1.405 0.217 1 0048523 negative regulation of cellular process P 0 0 0 0 0 4 9 1 44.44444 900 1.405 0.217 1 0008238 exopeptidase activity F 0 0 0 0 0 1 13 7 7.692307 185.7143 -1.403 0.217 1 0006560 proline metabolic process P 0 1 1 0 100 0 8 8 0 100 -1.607 0.218 1 0006561 proline biosynthetic process P 0 8 8 0 100 0 8 8 0 100 -1.607 0.218 1 0022414 reproductive process P 0 0 0 0 0 0 7 7 0 100 -1.503 0.219 1 0034062 RNA polymerase activity F 0 0 0 0 0 0 7 7 0 100 -1.503 0.219 1 0043093 FtsZ-dependent cytokinesis P 0 7 7 0 100 0 7 7 0 100 -1.503 0.219 1 0044702 single organism reproductive process P 0 0 0 0 0 0 7 7 0 100 -1.503 0.219 1 0000003 reproduction P 0 0 0 0 0 0 7 7 0 100 -1.503 0.219 1 0019954 asexual reproduction P 0 0 0 0 0 0 7 7 0 100 -1.503 0.219 1 0032505 reproduction of a single-celled organism P 0 0 0 0 0 0 7 7 0 100 -1.503 0.219 1 0003899 DNA-directed RNA polymerase activity F 0 7 7 0 100 0 7 7 0 100 -1.503 0.219 1 0042330 taxis P 0 0 0 0 0 1 14 14 7.142857 100 -1.505 0.219 1 0006935 chemotaxis P 1 14 14 7.142857 100 1 14 14 7.142857 100 -1.505 0.219 1 0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.22 1 0004068 aspartate 1-decarboxylase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.22 1 0006537 glutamate biosynthetic process P 2 4 4 50 100 2 4 4 50 100 1.195 0.221 1 0047547 2-methylcitrate dehydratase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.222 1 0019629 propionate catabolic process, 2-methylcitrate cycle P 1 1 1 100 100 1 1 1 100 100 1.762 0.222 1 0019543 propionate catabolic process P 0 0 0 0 0 1 1 1 100 100 1.762 0.222 1 0046459 short-chain fatty acid metabolic process P 0 0 0 0 0 1 1 1 100 100 1.762 0.222 1 0019541 propionate metabolic process P 0 0 0 0 0 1 1 1 100 100 1.762 0.222 1 0019626 short-chain fatty acid catabolic process P 0 0 0 0 0 1 1 1 100 100 1.762 0.222 1 0033013 tetrapyrrole metabolic process P 0 0 0 0 0 1 13 9 7.692307 144.4444 -1.403 0.222 1 0000910 cytokinesis P 0 0 0 0 0 1 14 9 7.142857 155.5556 -1.505 0.222 1 0008889 glycerophosphodiester phosphodiesterase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.223 1 0045184 establishment of protein localization P 0 0 0 0 0 19 60 43 31.66667 139.5349 1.333 0.223 1 0008104 protein localization P 0 0 0 0 0 19 60 43 31.66667 139.5349 1.333 0.223 1 0045229 external encapsulating structure organization P 0 0 0 0 0 3 24 17 12.5 141.1765 -1.36 0.223 1 0003952 NAD+ synthase (glutamine-hydrolyzing) activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.224 1 0004151 dihydroorotase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.224 1 0004585 ornithine carbamoyltransferase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.224 1 0004851 uroporphyrin-III C-methyltransferase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.225 1 0019354 siroheme biosynthetic process P 1 1 1 100 100 1 1 1 100 100 1.762 0.225 1 0009236 cobalamin biosynthetic process P 1 1 1 100 100 1 1 1 100 100 1.762 0.225 1 0051266 sirohydrochlorin ferrochelatase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.225 1 0046710 GDP metabolic process P 1 1 1 100 100 1 1 1 100 100 1.762 0.225 1 0004385 guanylate kinase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.225 1 0046156 siroheme metabolic process P 0 0 0 0 0 1 1 1 100 100 1.762 0.225 1 0043115 precorrin-2 dehydrogenase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.225 1 0004479 methionyl-tRNA formyltransferase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.225 1 0071951 conversion of methionyl-tRNA to N-formyl-methionyl-tRNA P 1 1 1 100 100 1 1 1 100 100 1.762 0.225 1 0019988 charged-tRNA amino acid modification P 0 0 0 0 0 1 1 1 100 100 1.762 0.225 1 0009235 cobalamin metabolic process P 0 0 0 0 0 1 1 1 100 100 1.762 0.225 1 0042128 nitrate assimilation P 1 1 1 100 100 1 1 1 100 100 1.762 0.226 1 0043546 molybdopterin cofactor binding F 1 1 1 100 100 1 1 1 100 100 1.762 0.226 1 0008176 tRNA (guanine-N7-)-methyltransferase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.226 1 0042126 nitrate metabolic process P 0 0 0 0 0 1 1 1 100 100 1.762 0.226 1 0008840 4-hydroxy-tetrahydrodipicolinate synthase F 1 1 1 100 100 1 1 1 100 100 1.762 0.226 1 2001057 reactive nitrogen species metabolic process P 0 0 0 0 0 1 1 1 100 100 1.762 0.226 1 0008757 S-adenosylmethionine-dependent methyltransferase activity F 0 2 2 0 100 3 23 3 13.04348 766.6667 -1.27 0.226 1 0047569 3-oxoadipate CoA-transferase activity F 2 4 4 50 100 2 4 4 50 100 1.195 0.227 1 0047134 protein-disulfide reductase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.228 1 0030272 5-formyltetrahydrofolate cyclo-ligase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.228 1 0047575 4-carboxymuconolactone decarboxylase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.229 1 0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.229 1 0009264 deoxyribonucleotide catabolic process P 1 1 1 100 100 1 1 1 100 100 1.762 0.229 1 0000702 oxidized base lesion DNA N-glycosylase activity F 0 0 0 0 0 1 1 1 100 100 1.762 0.229 1 0008691 3-hydroxybutyryl-CoA dehydrogenase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.231 1 0031072 heat shock protein binding F 1 1 1 100 100 1 1 1 100 100 1.762 0.231 1 0008728 GTP diphosphokinase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.231 1 0004424 imidazoleglycerol-phosphate dehydratase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.232 1 0018307 enzyme active site formation P 1 1 1 100 100 1 1 1 100 100 1.762 0.232 1 0019637 organophosphate metabolic process P 0 0 0 0 0 29 145 23 20 630.4348 -1.259 0.232 1 0008803 bis(5’-nucleosyl)-tetraphosphatase (symmetrical) activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.233 1 0004551 nucleotide diphosphatase activity F 0 0 0 0 0 1 1 1 100 100 1.762 0.233 1 0008796 bis(5’-nucleosyl)-tetraphosphatase activity F 0 0 0 0 0 1 1 1 100 100 1.762 0.233 1 0009060 aerobic respiration P 0 5 5 0 100 3 23 8 13.04348 287.5 -1.27 0.233 1 0016879 ligase activity, forming carbon-nitrogen bonds F 0 3 3 0 100 8 49 4 16.32653 1225 -1.323 0.233 1 0008460 dTDP-glucose 4,6-dehydratase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.235 1 0006515 misfolded or incompletely synthesized protein catabolic process P 1 1 1 100 100 1 1 1 100 100 1.762 0.235 1 0003849 3-deoxy-7-phosphoheptulonate synthase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.235 1 0004819 glutamine-tRNA ligase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.236 1 0004640 phosphoribosylanthranilate isomerase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.236 1 0017013 protein flavinylation P 1 1 1 100 100 1 1 1 100 100 1.762 0.236 1 0006425 glutaminyl-tRNA aminoacylation P 1 1 1 100 100 1 1 1 100 100 1.762 0.236 1 0019008 molybdopterin synthase complex C 1 1 1 100 100 1 1 1 100 100 1.762 0.236 1 0061597 cyclic pyranopterin monophosphate synthase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.236 1 1901292 nucleoside phosphate catabolic process P 0 0 0 0 0 2 4 2 50 200 1.195 0.236 1 0045181 glutamate synthase activity, NAD(P)H as acceptor F 0 0 0 0 0 1 1 1 100 100 1.762 0.237 1 0004355 glutamate synthase (NADPH) activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.237 1 0006741 NADP biosynthetic process P 1 1 1 100 100 1 1 1 100 100 1.762 0.237 1 0003951 NAD+ kinase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.237 1 0016223 beta-alanine-pyruvate transaminase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.238 1 0003949 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.238 1 0016863 intramolecular oxidoreductase activity, transposing C=C bonds F 0 0 0 0 0 1 1 1 100 100 1.762 0.238 1 0016159 muconolactone delta-isomerase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.238 1 0006568 tryptophan metabolic process P 1 3 4 33.33333 75 4 9 8 44.44444 112.5 1.405 0.238 1 0042430 indole-containing compound metabolic process P 0 0 0 0 0 4 9 8 44.44444 112.5 1.405 0.238 1 0006586 indolalkylamine metabolic process P 0 0 0 0 0 4 9 8 44.44444 112.5 1.405 0.238 1 0043168 anion binding F 0 0 0 0 0 100 452 292 22.12389 154.7945 -1.219 0.238 1 0016673 oxidoreductase activity, acting on a sulfur group of donors, iron-sulfur protein as acceptor F 0 0 0 0 0 1 1 1 100 100 1.762 0.239 1 0050311 sulfite reductase (ferredoxin) activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.239 1 0004602 glutathione peroxidase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.239 1 0052855 ADP-dependent NAD(P)H-hydrate dehydratase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.24 1 0006572 tyrosine catabolic process P 1 1 1 100 100 1 1 1 100 100 1.762 0.24 1 0006559 L-phenylalanine catabolic process P 1 1 1 100 100 1 1 1 100 100 1.762 0.24 1 0004411 homogentisate 1,2-dioxygenase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.24 1 1902222 erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process P 0 0 0 0 0 1 1 1 100 100 1.762 0.24 1 0008955 peptidoglycan glycosyltransferase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.24 1 0004358 glutamate N-acetyltransferase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.24 1 0043167 ion binding F 0 0 0 0 0 160 705 282 22.69504 250 -1.206 0.24 1 0002094 polyprenyltransferase activity F 0 0 0 0 0 1 1 1 100 100 1.762 0.241 1 0003859 3-hydroxybutyryl-CoA dehydratase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.241 1 0008412 4-hydroxybenzoate octaprenyltransferase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.241 1 1903531 negative regulation of secretion by cell P 0 0 0 0 0 1 1 1 100 100 1.762 0.242 1 0043758 acetate-CoA ligase (ADP-forming) activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.242 1 0004340 glucokinase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.242 1 0044571 [2Fe-2S] cluster assembly P 1 1 1 100 100 1 1 1 100 100 1.762 0.242 1 0019200 carbohydrate kinase activity F 0 0 0 0 0 1 1 1 100 100 1.762 0.242 1 0031071 cysteine desulfurase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.242 1 0009443 pyridoxal 5’-phosphate salvage P 1 1 1 100 100 1 1 1 100 100 1.762 0.242 1 0008478 pyridoxal kinase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.242 1 0043711 pilus organization P 1 1 1 100 100 1 1 1 100 100 1.762 0.242 1 0070003 threonine-type peptidase activity F 0 0 0 0 0 1 1 1 100 100 1.762 0.242 1 0005839 proteasome core complex C 1 1 1 100 100 1 1 1 100 100 1.762 0.242 1 0051048 negative regulation of secretion P 0 0 0 0 0 1 1 1 100 100 1.762 0.242 1 0004298 threonine-type endopeptidase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.242 1 0004396 hexokinase activity F 0 0 0 0 0 1 1 1 100 100 1.762 0.242 1 0051224 negative regulation of protein transport P 0 0 0 0 0 1 1 1 100 100 1.762 0.242 1 0051051 negative regulation of transport P 0 0 0 0 0 1 1 1 100 100 1.762 0.242 1 0050709 negative regulation of protein secretion P 1 1 1 100 100 1 1 1 100 100 1.762 0.242 1 0006950 response to stress P 7 9 9 77.77778 100 20 64 21 31.25 304.7619 1.299 0.242 1 0051992 UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.243 1 0004451 isocitrate lyase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.243 1 0071424 rRNA (cytosine-N4-)-methyltransferase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.243 1 0060589 nucleoside-triphosphatase regulator activity F 0 0 0 0 0 1 1 1 100 100 1.762 0.243 1 0060590 ATPase regulator activity F 0 0 0 0 0 1 1 1 100 100 1.762 0.243 1 0000774 adenyl-nucleotide exchange factor activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.243 1 0022833 mechanically gated channel activity F 0 0 0 0 0 1 1 1 100 100 1.762 0.244 1 0016412 serine O-acyltransferase activity F 0 0 0 0 0 1 1 1 100 100 1.762 0.244 1 0008381 mechanically-gated ion channel activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.244 1 0071214 cellular response to abiotic stimulus P 0 0 0 0 0 1 1 1 100 100 1.762 0.244 1 0071470 cellular response to osmotic stress P 1 1 1 100 100 1 1 1 100 100 1.762 0.244 1 0009001 serine O-acetyltransferase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.244 1 0006970 response to osmotic stress P 0 0 0 0 0 1 1 1 100 100 1.762 0.244 1 0003950 NAD+ ADP-ribosyltransferase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.245 1 0004146 dihydrofolate reductase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.245 1 0097266 phenylacetyl-CoA 1,2-epoxidase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.246 1 0015833 peptide transport P 4 9 9 44.44444 100 4 9 9 44.44444 100 1.405 0.246 1 0004791 thioredoxin-disulfide reductase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.247 1 0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors F 0 0 0 0 0 9 26 18 34.61538 144.4444 1.223 0.247 1 0005886 plasma membrane C 49 240 241 20.41667 99.58506 57 266 244 21.42857 109.0164 -1.176 0.247 1 0017168 5-oxoprolinase (ATP-hydrolyzing) activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.248 1 0097052 L-kynurenine metabolic process P 0 0 0 0 0 1 1 1 100 100 1.762 0.248 1 0008837 diaminopimelate epimerase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.248 1 0004076 biotin synthase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.248 1 0004765 shikimate kinase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.248 1 0097053 L-kynurenine catabolic process P 1 1 1 100 100 1 1 1 100 100 1.762 0.248 1 0030429 kynureninase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.248 1 0019805 quinolinate biosynthetic process P 1 1 1 100 100 1 1 1 100 100 1.762 0.248 1 0034627 ’de novo’ NAD biosynthetic process P 0 0 0 0 0 1 1 1 100 100 1.762 0.248 1 0034354 ’de novo’ NAD biosynthetic process from tryptophan P 1 1 1 100 100 1 1 1 100 100 1.762 0.248 1 0046874 quinolinate metabolic process P 0 0 0 0 0 1 1 1 100 100 1.762 0.248 1 0004871 signal transducer activity F 3 16 16 18.75 100 4 28 26 14.28571 107.6923 -1.249 0.248 1 0004831 tyrosine-tRNA ligase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.249 1 0006437 tyrosyl-tRNA aminoacylation P 1 1 1 100 100 1 1 1 100 100 1.762 0.249 1 0003857 3-hydroxyacyl-CoA dehydrogenase activity F 2 4 4 50 100 2 4 4 50 100 1.195 0.249 1 0042026 protein refolding P 1 1 1 100 100 1 1 1 100 100 1.762 0.25 1 0002098 tRNA wobble uridine modification P 1 1 1 100 100 1 1 1 100 100 1.762 0.25 1 0016741 transferase activity, transferring one-carbon groups F 0 0 0 0 0 9 52 42 17.30769 123.8095 -1.197 0.25 1 0033819 lipoyl(octanoyl) transferase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.251 1 0016415 octanoyltransferase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.251 1 0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing C 1 1 1 100 100 1 1 1 100 100 1.762 0.251 1 0009326 formate dehydrogenase complex C 1 1 1 100 100 1 1 1 100 100 1.762 0.251 1 0030256 type I protein secretion system complex C 1 1 1 100 100 1 1 1 100 100 1.762 0.252 1 0045936 negative regulation of phosphate metabolic process P 1 1 1 100 100 1 1 1 100 100 1.762 0.252 1 0030320 cellular monovalent inorganic anion homeostasis P 0 0 0 0 0 1 1 1 100 100 1.762 0.252 1 0030002 cellular anion homeostasis P 0 0 0 0 0 1 1 1 100 100 1.762 0.252 1 0072502 cellular trivalent inorganic anion homeostasis P 0 0 0 0 0 1 1 1 100 100 1.762 0.252 1 0030253 protein secretion by the type I secretion system P 1 1 1 100 100 1 1 1 100 100 1.762 0.252 1 0010563 negative regulation of phosphorus metabolic process P 0 0 0 0 0 1 1 1 100 100 1.762 0.252 1 0030643 cellular phosphate ion homeostasis P 1 1 1 100 100 1 1 1 100 100 1.762 0.252 1 0031992 energy transducer activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.252 1 0072501 cellular divalent inorganic anion homeostasis P 0 0 0 0 0 1 1 1 100 100 1.762 0.252 1 0072505 divalent inorganic anion homeostasis P 0 0 0 0 0 1 1 1 100 100 1.762 0.252 1 0072506 trivalent inorganic anion homeostasis P 0 0 0 0 0 1 1 1 100 100 1.762 0.252 1 0008234 cysteine-type peptidase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.252 1 0055083 monovalent inorganic anion homeostasis P 0 0 0 0 0 1 1 1 100 100 1.762 0.252 1 0055081 anion homeostasis P 0 0 0 0 0 1 1 1 100 100 1.762 0.252 1 0055062 phosphate ion homeostasis P 0 0 0 0 0 1 1 1 100 100 1.762 0.252 1 0034023 5-(carboxyamino)imidazole ribonucleotide mutase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.252 1 0019220 regulation of phosphate metabolic process P 0 0 0 0 0 1 1 1 100 100 1.762 0.252 1 0051174 regulation of phosphorus metabolic process P 0 0 0 0 0 1 1 1 100 100 1.762 0.252 1 0004333 fumarate hydratase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.253 1 0006106 fumarate metabolic process P 1 1 1 100 100 1 1 1 100 100 1.762 0.253 1 0008294 calcium- and calmodulin-responsive adenylate cyclase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.253 1 0009190 cyclic nucleotide biosynthetic process P 0 0 0 0 0 1 1 1 100 100 1.762 0.253 1 0004817 cysteine-tRNA ligase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.253 1 0051480 cytosolic calcium ion homeostasis P 0 0 0 0 0 1 1 1 100 100 1.762 0.253 1 0072503 cellular divalent inorganic cation homeostasis P 0 0 0 0 0 1 1 1 100 100 1.762 0.253 1 0007204 positive regulation of cytosolic calcium ion concentration P 1 1 1 100 100 1 1 1 100 100 1.762 0.253 1 0008714 AMP nucleosidase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.253 1 0009187 cyclic nucleotide metabolic process P 0 0 0 0 0 1 1 1 100 100 1.762 0.253 1 0006171 cAMP biosynthetic process P 1 1 1 100 100 1 1 1 100 100 1.762 0.253 1 0046058 cAMP metabolic process P 0 0 0 0 0 1 1 1 100 100 1.762 0.253 1 0006423 cysteinyl-tRNA aminoacylation P 1 1 1 100 100 1 1 1 100 100 1.762 0.253 1 0005509 calcium ion binding F 1 1 1 100 100 1 1 1 100 100 1.762 0.253 1 0006874 cellular calcium ion homeostasis P 0 0 0 0 0 1 1 1 100 100 1.762 0.253 1 0052652 cyclic purine nucleotide metabolic process P 0 0 0 0 0 1 1 1 100 100 1.762 0.253 1 0004016 adenylate cyclase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.253 1 0055074 calcium ion homeostasis P 0 0 0 0 0 1 1 1 100 100 1.762 0.253 1 0009975 cyclase activity F 0 0 0 0 0 1 1 1 100 100 1.762 0.253 1 0004107 chorismate synthase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.253 1 0005516 calmodulin binding F 1 1 1 100 100 1 1 1 100 100 1.762 0.253 1 0072507 divalent inorganic cation homeostasis P 0 0 0 0 0 1 1 1 100 100 1.762 0.253 1 0045934 negative regulation of nucleobase-containing compound metabolic process P 0 0 0 0 0 2 4 3 50 133.3333 1.195 0.255 1 0003688 DNA replication origin binding F 1 1 1 100 100 1 1 1 100 100 1.762 0.256 1 1990837 sequence-specific double-stranded DNA binding F 0 0 0 0 0 1 1 1 100 100 1.762 0.256 1 0004644 phosphoribosylglycinamide formyltransferase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.256 1 0019395 fatty acid oxidation P 0 0 0 0 0 1 1 1 100 100 1.762 0.256 1 0006635 fatty acid beta-oxidation P 1 1 1 100 100 1 1 1 100 100 1.762 0.256 1 0034440 lipid oxidation P 0 0 0 0 0 1 1 1 100 100 1.762 0.256 1 0043815 phosphoribosylglycinamide formyltransferase 2 activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.256 1 0042592 homeostatic process P 0 0 0 0 0 9 26 1 34.61538 2600 1.223 0.256 1 0018796 4,5-dihydroxyphthalate decarboxylase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.257 1 0016722 oxidoreductase activity, oxidizing metal ions F 1 1 1 100 100 1 1 1 100 100 1.762 0.258 1 0003917 DNA topoisomerase type I activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.259 1 0008295 spermidine biosynthetic process P 1 1 1 100 100 1 1 1 100 100 1.762 0.26 1 0008216 spermidine metabolic process P 0 0 0 0 0 1 1 1 100 100 1.762 0.26 1 0097164 ammonium ion metabolic process P 0 0 0 0 0 1 1 1 100 100 1.762 0.26 1 0006595 polyamine metabolic process P 0 0 0 0 0 1 1 1 100 100 1.762 0.26 1 0006596 polyamine biosynthetic process P 1 1 1 100 100 1 1 1 100 100 1.762 0.26 1 0004799 thymidylate synthase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.261 1 0006231 dTMP biosynthetic process P 1 1 1 100 100 1 1 1 100 100 1.762 0.261 1 0042083 5,10-methylenetetrahydrofolate-dependent methyltransferase activity F 0 0 0 0 0 1 1 1 100 100 1.762 0.261 1 0046073 dTMP metabolic process P 0 0 0 0 0 1 1 1 100 100 1.762 0.261 1 0006801 superoxide metabolic process P 1 3 3 33.33333 100 2 4 4 50 100 1.195 0.261 1 1901700 response to oxygen-containing compound P 0 0 0 0 0 2 4 4 50 100 1.195 0.261 1 0000302 response to reactive oxygen species P 0 0 0 0 0 2 4 4 50 100 1.195 0.261 1 0000305 response to oxygen radical P 0 0 0 0 0 2 4 4 50 100 1.195 0.261 1 0019430 removal of superoxide radicals P 2 4 4 50 100 2 4 4 50 100 1.195 0.261 1 0000303 response to superoxide P 0 0 0 0 0 2 4 4 50 100 1.195 0.261 1 1901701 cellular response to oxygen-containing compound P 0 0 0 0 0 2 4 4 50 100 1.195 0.261 1 0034599 cellular response to oxidative stress P 0 0 0 0 0 2 4 4 50 100 1.195 0.261 1 0034614 cellular response to reactive oxygen species P 0 0 0 0 0 2 4 4 50 100 1.195 0.261 1 0071451 cellular response to superoxide P 0 0 0 0 0 2 4 4 50 100 1.195 0.261 1 0071450 cellular response to oxygen radical P 0 0 0 0 0 2 4 4 50 100 1.195 0.261 1 0051289 protein homotetramerization P 1 1 1 100 100 1 1 1 100 100 1.762 0.262 1 0004833 tryptophan 2,3-dioxygenase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.262 1 0003941 L-serine ammonia-lyase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.262 1 0051260 protein homooligomerization P 0 0 0 0 0 1 1 1 100 100 1.762 0.262 1 0016042 lipid catabolic process P 0 2 2 0 100 2 4 3 50 133.3333 1.195 0.262 1 0043335 protein unfolding P 1 1 1 100 100 1 1 1 100 100 1.762 0.263 1 0032259 methylation P 7 43 43 16.27907 100 7 43 43 16.27907 100 -1.245 0.264 1 0008168 methyltransferase activity F 7 42 42 16.66667 100 7 43 42 16.27907 102.381 -1.245 0.264 1 0008033 tRNA processing P 3 25 25 12 100 4 28 25 14.28571 112 -1.249 0.264 1 0004474 malate synthase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.265 1 0004334 fumarylacetoacetase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.266 1 0004516 nicotinate phosphoribosyltransferase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.267 1 0019357 nicotinate nucleotide biosynthetic process P 1 1 1 100 100 1 1 1 100 100 1.762 0.267 1 0046497 nicotinate nucleotide metabolic process P 0 0 0 0 0 1 1 1 100 100 1.762 0.267 1 0047570 3-oxoadipate enol-lactonase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.268 1 0033743 peptide-methionine (R)-S-oxide reductase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.268 1 0008271 secondary active sulfate transmembrane transporter activity F 2 4 4 50 100 2 4 4 50 100 1.195 0.27 1 0050076 maleate isomerase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.271 1 0019120 hydrolase activity, acting on acid halide bonds, in C-halide compounds F 1 1 1 100 100 1 1 1 100 100 1.762 0.271 1 0016824 hydrolase activity, acting on acid halide bonds F 0 0 0 0 0 1 1 1 100 100 1.762 0.271 1 0046916 cellular transition metal ion homeostasis P 0 0 0 0 0 2 4 3 50 133.3333 1.195 0.271 1 0004368 glycerol-3-phosphate dehydrogenase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.273 1 0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor F 0 0 0 0 0 1 1 1 100 100 1.762 0.273 1 0009403 toxin biosynthetic process P 1 1 1 100 100 1 1 1 100 100 1.762 0.274 1 0004743 pyruvate kinase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.274 1 0009168 purine ribonucleoside monophosphate biosynthetic process P 0 0 0 0 0 4 27 3 14.81481 900 -1.162 0.275 1 0009127 purine nucleoside monophosphate biosynthetic process P 0 0 0 0 0 4 27 3 14.81481 900 -1.162 0.275 1 0046939 nucleotide phosphorylation P 0 4 4 0 100 2 17 17 11.76471 100 -1.214 0.276 1 0015645 fatty acid ligase activity F 0 0 0 0 0 1 1 1 100 100 1.762 0.277 1 0001676 long-chain fatty acid metabolic process P 1 1 1 100 100 1 1 1 100 100 1.762 0.277 1 0004467 long-chain fatty acid-CoA ligase activity F 1 1 1 100 100 1 1 1 100 100 1.762 0.277 1 0043650 dicarboxylic acid biosynthetic process P 0 0 0 0 0 7 19 5 36.84211 380 1.271 0.277 1 0022804 active transmembrane transporter activity F 0 0 0 0 0 10 57 16 17.54386 356.25 -1.212 0.277 1 0009451 RNA modification P 1 8 8 12.5 100 6 37 8 16.21622 462.5 -1.163 0.28 1 0001510 RNA methylation P 0 5 5 0 100 2 17 7 11.76471 242.8571 -1.214 0.28 1 0009067 aspartate family amino acid biosynthetic process P 0 0 0 0 0 2 17 8 11.76471 212.5 -1.214 0.285 1 0033554 cellular response to stress P 1 1 1 100 100 7 43 37 16.27907 116.2162 -1.245 0.285 1 0016627 oxidoreductase activity, acting on the CH-CH group of donors F 4 20 20 20 100 5 32 20 15.625 160 -1.158 0.295 1 0016614 oxidoreductase activity, acting on CH-OH group of donors F 5 13 13 38.46154 100 12 64 35 18.75 182.8571 -1.059 0.296 1 0022607 cellular component assembly P 0 0 0 0 0 14 44 9 31.81818 488.8889 1.161 0.297 1 0009112 nucleobase metabolic process P 0 0 0 0 0 1 11 4 9.090909 275 -1.182 0.298 1 0044802 single-organism membrane organization P 0 0 0 0 0 1 11 5 9.090909 220 -1.182 0.298 1 0061024 membrane organization P 0 1 1 0 100 1 11 6 9.090909 183.3333 -1.182 0.298 1 0006928 movement of cell or subcellular component P 0 0 0 0 0 3 21 21 14.28571 100 -1.08 0.3 1 0001539 cilium or flagellum-dependent cell motility P 0 3 3 0 100 3 21 21 14.28571 100 -1.08 0.3 1 0097588 archaeal or bacterial-type flagellum-dependent cell motility P 0 1 1 0 100 3 21 21 14.28571 100 -1.08 0.3 1 0048870 cell motility P 0 0 0 0 0 3 21 21 14.28571 100 -1.08 0.3 1 0051674 localization of cell P 0 0 0 0 0 3 21 21 14.28571 100 -1.08 0.3 1 0070925 organelle assembly P 0 0 0 0 0 1 12 2 8.333333 600 -1.296 0.302 1 0022904 respiratory electron transport chain P 1 6 6 16.66667 100 1 12 6 8.333333 200 -1.296 0.304 1 0046131 pyrimidine ribonucleoside metabolic process P 0 0 0 0 0 1 11 7 9.090909 157.1429 -1.182 0.306 1 0006213 pyrimidine nucleoside metabolic process P 0 0 0 0 0 1 11 7 9.090909 157.1429 -1.182 0.306 1 0046134 pyrimidine nucleoside biosynthetic process P 0 0 0 0 0 1 11 7 9.090909 157.1429 -1.182 0.306 1 0046132 pyrimidine ribonucleoside biosynthetic process P 0 0 0 0 0 1 11 7 9.090909 157.1429 -1.182 0.306 1 0007154 cell communication P 0 0 0 0 0 11 60 8 18.33333 750 -1.101 0.309 1 0016874 ligase activity F 14 79 79 17.72152 100 19 98 79 19.38775 124.0506 -1.169 0.314 1 0006526 arginine biosynthetic process P 5 13 13 38.46154 100 5 13 13 38.46154 100 1.187 0.315 1 0070546 L-phenylalanine aminotransferase activity F 0 0 0 0 0 0 5 5 0 100 -1.27 0.315 1 0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity F 0 5 5 0 100 0 5 5 0 100 -1.27 0.315 1 0090407 organophosphate biosynthetic process P 0 0 0 0 0 22 109 23 20.18349 473.9131 -1.038 0.317 1 0009396 folic acid-containing compound biosynthetic process P 0 9 9 0 100 1 11 11 9.090909 100 -1.182 0.317 1 0000096 sulfur amino acid metabolic process P 0 0 0 0 0 1 12 8 8.333333 150 -1.296 0.317 1 0009220 pyrimidine ribonucleotide biosynthetic process P 0 1 1 0 100 1 12 8 8.333333 150 -1.296 0.318 1 0009218 pyrimidine ribonucleotide metabolic process P 0 0 0 0 0 1 12 8 8.333333 150 -1.296 0.318 1 0009201 ribonucleoside triphosphate biosynthetic process P 0 0 0 0 0 1 12 9 8.333333 133.3333 -1.296 0.32 1 0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen F 0 5 5 0 100 1 11 5 9.090909 220 -1.182 0.321 1 0006464 cellular protein modification process P 2 6 6 33.33333 100 9 50 16 18 312.5 -1.058 0.324 1 0036211 protein modification process P 0 0 0 0 0 9 50 16 18 312.5 -1.058 0.324 1 0046490 isopentenyl diphosphate metabolic process P 0 0 0 0 0 0 6 6 0 100 -1.392 0.325 1 0019288 isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway P 0 6 6 0 100 0 6 6 0 100 -1.392 0.325 1 0009240 isopentenyl diphosphate biosynthetic process P 0 0 0 0 0 0 6 6 0 100 -1.392 0.325 1 0006310 DNA recombination P 2 19 19 10.52632 100 3 22 30 13.63636 73.33334 -1.177 0.326 1 0043624 cellular protein complex disassembly P 0 0 0 0 0 0 5 5 0 100 -1.27 0.326 1 1901677 phosphate transmembrane transporter activity F 0 0 0 0 0 0 5 1 0 500 -1.27 0.326 1 0006415 translational termination P 0 5 5 0 100 0 5 5 0 100 -1.27 0.326 1 0031167 rRNA methylation P 0 7 7 0 100 1 12 9 8.333333 133.3333 -1.296 0.327 1 0000154 rRNA modification P 0 1 1 0 100 1 12 9 8.333333 133.3333 -1.296 0.327 1 0005829 cytosol C 2 8 8 25 100 5 13 10 38.46154 130 1.187 0.328 1 0006520 cellular amino acid metabolic process P 2 15 15 13.33333 100 33 159 80 20.75472 198.75 -1.094 0.328 1 0008649 rRNA methyltransferase activity F 0 4 4 0 100 1 11 5 9.090909 220 -1.182 0.328 1 0005057 receptor signaling protein activity F 0 0 0 0 0 3 21 18 14.28571 116.6667 -1.08 0.329 1 0008172 S-methyltransferase activity F 0 0 0 0 0 0 5 2 0 250 -1.27 0.33 1 0016708 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor F 0 4 4 0 100 0 5 5 0 100 -1.27 0.331 1 0006778 porphyrin-containing compound metabolic process P 0 0 0 0 0 1 12 9 8.333333 133.3333 -1.296 0.331 1 0043190 ATP-binding cassette (ABC) transporter complex C 11 36 36 30.55556 100 12 37 37 32.43243 100 1.151 0.332 1 1902495 transmembrane transporter complex C 0 0 0 0 0 12 37 37 32.43243 100 1.151 0.332 1 1990351 transporter complex C 0 0 0 0 0 12 37 37 32.43243 100 1.151 0.332 1 0098533 ATPase dependent transmembrane transport complex C 0 0 0 0 0 12 37 37 32.43243 100 1.151 0.332 1 0006525 arginine metabolic process P 2 3 3 66.66666 100 5 14 14 35.71429 100 0.992 0.332 1 0051287 NAD binding F 5 33 33 15.15152 100 6 35 35 17.14286 100 -1.002 0.332 1 0000413 protein peptidyl-prolyl isomerization P 0 6 6 0 100 0 6 6 0 100 -1.392 0.332 1 0018208 peptidyl-proline modification P 0 0 0 0 0 0 6 6 0 100 -1.392 0.332 1 0003755 peptidyl-prolyl cis-trans isomerase activity F 0 6 6 0 100 0 6 6 0 100 -1.392 0.332 1 0006508 proteolysis P 16 52 52 30.76923 100 17 56 52 30.35714 107.6923 1.056 0.333 1 0043039 tRNA aminoacylation P 1 5 5 20 100 3 21 18 14.28571 116.6667 -1.08 0.333 1 0016876 ligase activity, forming aminoacyl-tRNA and related compounds F 1 4 4 25 100 3 21 21 14.28571 100 -1.08 0.333 1 0016875 ligase activity, forming carbon-oxygen bonds F 0 0 0 0 0 3 21 21 14.28571 100 -1.08 0.333 1 0004812 aminoacyl-tRNA ligase activity F 3 21 21 14.28571 100 3 21 21 14.28571 100 -1.08 0.333 1 0043038 amino acid activation P 0 0 0 0 0 3 21 18 14.28571 116.6667 -1.08 0.333 1 0006418 tRNA aminoacylation for protein translation P 3 17 17 17.64706 100 3 21 17 14.28571 123.5294 -1.08 0.333 1 0030694 bacterial-type flagellum basal body, rod C 0 2 2 0 100 0 5 4 0 125 -1.27 0.334 1 0055086 nucleobase-containing small molecule metabolic process P 0 0 0 0 0 21 103 23 20.38835 447.8261 -0.959 0.335 1 0006468 protein phosphorylation P 0 4 4 0 100 3 21 10 14.28571 210 -1.08 0.335 1 0004672 protein kinase activity F 0 2 2 0 100 3 21 19 14.28571 110.5263 -1.08 0.335 1 0008827 cytochrome o ubiquinol oxidase activity F 0 5 5 0 100 0 5 5 0 100 -1.27 0.335 1 0006779 porphyrin-containing compound biosynthetic process P 1 9 9 11.11111 100 1 11 9 9.090909 122.2222 -1.182 0.337 1 0004316 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity F 0 5 5 0 100 0 5 5 0 100 -1.27 0.337 1 0033014 tetrapyrrole biosynthetic process P 0 5 5 0 100 1 12 10 8.333333 120 -1.296 0.339 1 0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5’-phosphomonoesters F 0 0 0 0 0 0 6 2 0 300 -1.392 0.339 1 0046501 protoporphyrinogen IX metabolic process P 0 0 0 0 0 0 5 5 0 100 -1.27 0.34 1 0006782 protoporphyrinogen IX biosynthetic process P 0 5 5 0 100 0 5 5 0 100 -1.27 0.34 1 0019725 cellular homeostasis P 0 0 0 0 0 8 23 1 34.78261 2300 1.169 0.341 1 0006066 alcohol metabolic process P 0 0 0 0 0 0 6 1 0 600 -1.392 0.342 1 0033178 proton-transporting two-sector ATPase complex, catalytic domain C 0 2 2 0 100 0 5 5 0 100 -1.27 0.343 1 0045261 proton-transporting ATP synthase complex, catalytic core F(1) C 0 5 5 0 100 0 5 5 0 100 -1.27 0.343 1 0016774 phosphotransferase activity, carboxyl group as acceptor F 0 1 1 0 100 0 5 2 0 250 -1.27 0.345 1 0006563 L-serine metabolic process P 0 1 1 0 100 0 5 1 0 500 -1.27 0.345 1 0009226 nucleotide-sugar biosynthetic process P 0 0 0 0 0 0 5 1 0 500 -1.27 0.346 1 0004888 transmembrane signaling receptor activity F 0 5 5 0 100 0 5 5 0 100 -1.27 0.346 1 0018106 peptidyl-histidine phosphorylation P 0 6 6 0 100 0 6 6 0 100 -1.392 0.347 1 0018202 peptidyl-histidine modification P 0 0 0 0 0 0 6 6 0 100 -1.392 0.347 1 0046394 carboxylic acid biosynthetic process P 0 0 0 0 0 26 127 69 20.47244 184.058 -1.047 0.349 1 0016053 organic acid biosynthetic process P 0 0 0 0 0 26 127 69 20.47244 184.058 -1.047 0.349 1 0019238 cyclohydrolase activity F 0 0 0 0 0 0 5 1 0 500 -1.27 0.349 1 0006869 lipid transport P 0 1 1 0 100 0 5 2 0 250 -1.27 0.35 1 0010876 lipid localization P 0 0 0 0 0 0 5 2 0 250 -1.27 0.35 1 0008616 queuosine biosynthetic process P 0 5 5 0 100 0 5 5 0 100 -1.27 0.351 1 0046116 queuosine metabolic process P 0 0 0 0 0 0 5 5 0 100 -1.27 0.351 1 0004521 endoribonuclease activity F 0 2 2 0 100 0 6 4 0 150 -1.392 0.351 1 0090502 RNA phosphodiester bond hydrolysis, endonucleolytic P 0 6 6 0 100 0 6 6 0 100 -1.392 0.351 1 0035383 thioester metabolic process P 0 0 0 0 0 0 6 2 0 300 -1.392 0.352 1 0006637 acyl-CoA metabolic process P 0 0 0 0 0 0 6 2 0 300 -1.392 0.352 1 0044271 cellular nitrogen compound biosynthetic process P 0 0 0 0 0 120 528 275 22.72727 192 -0.98 0.353 1 0009288 bacterial-type flagellum C 2 23 23 8.695652 100 4 26 23 15.38461 113.0435 -1.072 0.353 1 0016773 phosphotransferase activity, alcohol group as acceptor F 0 6 6 0 100 7 40 25 17.5 160 -1.019 0.354 1 0008615 pyridoxine biosynthetic process P 0 5 5 0 100 0 5 5 0 100 -1.27 0.354 1 0042816 vitamin B6 metabolic process P 0 1 1 0 100 0 5 5 0 100 -1.27 0.354 1 0042819 vitamin B6 biosynthetic process P 0 0 0 0 0 0 5 5 0 100 -1.27 0.354 1 0008614 pyridoxine metabolic process P 0 0 0 0 0 0 5 5 0 100 -1.27 0.354 1 0005488 binding F 0 0 0 0 0 274 1164 282 23.53952 412.766 -0.877 0.355 1 0015988 energy coupled proton transmembrane transport, against electrochemical gradient P 0 0 0 0 0 0 5 3 0 166.6667 -1.27 0.355 1 0015937 coenzyme A biosynthetic process P 0 4 4 0 100 0 6 6 0 100 -1.392 0.355 1 0034030 ribonucleoside bisphosphate biosynthetic process P 0 0 0 0 0 0 6 6 0 100 -1.392 0.355 1 0015936 coenzyme A metabolic process P 0 0 0 0 0 0 6 6 0 100 -1.392 0.355 1 0033866 nucleoside bisphosphate biosynthetic process P 0 0 0 0 0 0 6 6 0 100 -1.392 0.355 1 0034033 purine nucleoside bisphosphate biosynthetic process P 0 0 0 0 0 0 6 6 0 100 -1.392 0.355 1 0042773 ATP synthesis coupled electron transport P 0 6 6 0 100 0 6 6 0 100 -1.392 0.355 1 0006401 RNA catabolic process P 0 2 2 0 100 0 5 4 0 125 -1.27 0.356 1 0016615 malate dehydrogenase activity F 0 1 1 0 100 0 5 4 0 125 -1.27 0.359 1 0006207 ’de novo’ pyrimidine nucleobase biosynthetic process P 0 5 5 0 100 0 5 5 0 100 -1.27 0.36 1 0016421 CoA carboxylase activity F 0 0 0 0 0 0 6 2 0 300 -1.392 0.36 1 0016885 ligase activity, forming carbon-carbon bonds F 0 0 0 0 0 0 6 2 0 300 -1.392 0.36 1 0006024 glycosaminoglycan biosynthetic process P 0 0 0 0 0 2 16 17 12.5 94.11765 -1.109 0.361 1 0006023 aminoglycan biosynthetic process P 0 0 0 0 0 2 16 17 12.5 94.11765 -1.109 0.361 1 0009273 peptidoglycan-based cell wall biogenesis P 0 0 0 0 0 2 16 17 12.5 94.11765 -1.109 0.361 1 0009252 peptidoglycan biosynthetic process P 2 16 17 12.5 94.11765 2 16 17 12.5 94.11765 -1.109 0.361 1 0044038 cell wall macromolecule biosynthetic process P 0 0 0 0 0 2 16 17 12.5 94.11765 -1.109 0.361 1 0070589 cellular component macromolecule biosynthetic process P 0 0 0 0 0 2 16 17 12.5 94.11765 -1.109 0.361 1 0044036 cell wall macromolecule metabolic process P 0 0 0 0 0 2 16 17 12.5 94.11765 -1.109 0.361 1 0042546 cell wall biogenesis P 0 0 0 0 0 2 16 17 12.5 94.11765 -1.109 0.361 1 0015079 potassium ion transmembrane transporter activity F 0 2 2 0 100 0 6 3 0 200 -1.392 0.362 1 0009231 riboflavin biosynthetic process P 0 6 6 0 100 0 6 6 0 100 -1.392 0.362 1 0071805 potassium ion transmembrane transport P 0 6 6 0 100 0 6 6 0 100 -1.392 0.362 1 0071804 cellular potassium ion transport P 0 0 0 0 0 0 6 6 0 100 -1.392 0.362 1 0006771 riboflavin metabolic process P 0 0 0 0 0 0 6 6 0 100 -1.392 0.362 1 0042726 flavin-containing compound metabolic process P 0 0 0 0 0 0 6 6 0 100 -1.392 0.362 1 0042727 flavin-containing compound biosynthetic process P 0 0 0 0 0 0 6 6 0 100 -1.392 0.362 1 1990234 transferase complex C 0 0 0 0 0 0 6 3 0 200 -1.392 0.364 1 0042623 ATPase activity, coupled F 0 0 0 0 0 11 59 10 18.64407 590 -1.035 0.365 1 0009425 bacterial-type flagellum basal body C 2 16 16 12.5 100 2 16 16 12.5 100 -1.109 0.367 1 0016857 racemase and epimerase activity, acting on carbohydrates and derivatives F 0 2 2 0 100 0 5 3 0 166.6667 -1.27 0.371 1 0044764 multi-organism cellular process P 0 0 0 0 0 3 7 4 42.85714 175 1.141 0.372 1 0009142 nucleoside triphosphate biosynthetic process P 0 0 0 0 0 2 15 9 13.33333 166.6667 -0.998 0.372 1 0009423 chorismate biosynthetic process P 3 7 7 42.85714 100 3 7 7 42.85714 100 1.141 0.373 1 0006414 translational elongation P 1 8 8 12.5 100 2 15 14 13.33333 107.1429 -0.998 0.373 1 0048037 cofactor binding F 2 5 5 40 100 48 176 26 27.27273 676.9231 0.93 0.374 1 0032153 cell division site C 0 6 6 0 100 0 6 6 0 100 -1.392 0.377 1 0008173 RNA methyltransferase activity F 0 6 6 0 100 2 16 7 12.5 228.5714 -1.109 0.378 1 0072524 pyridine-containing compound metabolic process P 0 0 0 0 0 10 31 13 32.25806 238.4615 1.03 0.379 1 0006221 pyrimidine nucleotide biosynthetic process P 1 9 9 11.11111 100 2 15 10 13.33333 150 -0.998 0.379 1 0072348 sulfur compound transport P 0 0 0 0 0 3 8 1 37.5 800 0.867 0.381 1 0006220 pyrimidine nucleotide metabolic process P 0 1 1 0 100 2 16 11 12.5 145.4545 -1.109 0.382 1 0047475 phenylacetate-CoA ligase activity F 1 2 2 50 100 1 2 2 50 100 0.845 0.385 1 0019842 vitamin binding F 0 0 0 0 0 5 14 1 35.71429 1400 0.992 0.387 1 0098661 inorganic anion transmembrane transport P 0 0 0 0 0 3 8 5 37.5 160 0.867 0.389 1 0009081 branched-chain amino acid metabolic process P 0 1 1 0 100 2 16 9 12.5 177.7778 -1.109 0.391 1 0071555 cell wall organization P 2 16 17 12.5 94.11765 2 16 17 12.5 94.11765 -1.109 0.391 1 0032049 cardiolipin biosynthetic process P 1 2 2 50 100 1 2 2 50 100 0.845 0.397 1 0008808 cardiolipin synthase activity F 1 2 2 50 100 1 2 2 50 100 0.845 0.397 1 0032048 cardiolipin metabolic process P 0 0 0 0 0 1 2 2 50 100 0.845 0.397 1 0030572 phosphatidyltransferase activity F 0 0 0 0 0 1 2 2 50 100 0.845 0.397 1 0036260 RNA capping P 0 0 0 0 0 1 2 2 50 100 0.845 0.398 1 0009452 7-methylguanosine RNA capping P 0 0 0 0 0 1 2 2 50 100 0.845 0.398 1 0009249 protein lipoylation P 1 2 2 50 100 1 2 2 50 100 0.845 0.398 1 0036265 RNA (guanine-N7)-methylation P 1 1 1 100 100 1 2 2 50 100 0.845 0.398 1 0004460 L-lactate dehydrogenase (cytochrome) activity F 1 2 2 50 100 1 2 2 50 100 0.845 0.399 1 0016898 oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor F 0 0 0 0 0 1 2 2 50 100 0.845 0.399 1 0006633 fatty acid biosynthetic process P 0 14 14 0 100 2 16 16 12.5 100 -1.109 0.4 1 0015035 protein disulfide oxidoreductase activity F 3 8 8 37.5 100 3 8 8 37.5 100 0.867 0.403 1 0006591 ornithine metabolic process P 1 1 1 100 100 1 2 2 50 100 0.845 0.403 1 0009057 macromolecule catabolic process P 0 0 0 0 0 6 18 4 33.33333 450 0.889 0.404 1 0046906 tetrapyrrole binding F 0 0 0 0 0 5 29 28 17.24138 103.5714 -0.898 0.405 1 0008135 translation factor activity, RNA binding F 0 0 0 0 0 2 16 8 12.5 200 -1.109 0.405 1 0004042 acetyl-CoA:L-glutamate N-acetyltransferase activity F 1 2 2 50 100 1 2 2 50 100 0.845 0.407 1 1901136 carbohydrate derivative catabolic process P 0 0 0 0 0 3 8 1 37.5 800 0.867 0.408 1 0016423 tRNA (guanine) methyltransferase activity F 0 0 0 0 0 1 2 1 50 200 0.845 0.408 1 0004121 cystathionine beta-lyase activity F 1 2 2 50 100 1 2 2 50 100 0.845 0.408 1 0046700 heterocycle catabolic process P 0 0 0 0 0 6 17 4 35.29412 425 1.053 0.409 1 0004175 endopeptidase activity F 0 0 0 0 0 7 21 7 33.33333 300 0.961 0.409 1 0016799 hydrolase activity, hydrolyzing N-glycosyl compounds F 1 2 2 50 100 3 8 5 37.5 160 0.867 0.409 1 0046417 chorismate metabolic process P 0 1 1 0 100 3 8 8 37.5 100 0.867 0.41 1 0044085 cellular component biogenesis P 0 0 0 0 0 17 84 9 20.23809 933.3333 -0.895 0.411 1 0070011 peptidase activity, acting on L-amino acid peptides F 1 1 1 100 100 15 50 2 30 2500 0.937 0.412 1 0008233 peptidase activity F 8 26 26 30.76923 100 15 51 27 29.41176 188.8889 0.848 0.413 1 0004325 ferrochelatase activity F 1 2 2 50 100 1 2 2 50 100 0.845 0.413 1 0043934 sporulation P 0 0 0 0 0 1 2 2 50 100 0.845 0.413 1 0030435 sporulation resulting in formation of a cellular spore P 1 2 2 50 100 1 2 2 50 100 0.845 0.413 1 0048646 anatomical structure formation involved in morphogenesis P 0 0 0 0 0 1 2 2 50 100 0.845 0.413 1 0030154 cell differentiation P 0 0 0 0 0 1 2 2 50 100 0.845 0.413 1 0015849 organic acid transport P 0 0 0 0 0 6 33 19 18.18182 173.6842 -0.832 0.413 1 0046942 carboxylic acid transport P 0 0 0 0 0 6 33 19 18.18182 173.6842 -0.832 0.413 1 0031406 carboxylic acid binding F 0 0 0 0 0 3 20 1 15 2000 -0.979 0.413 1 0043177 organic acid binding F 0 0 0 0 0 3 20 1 15 2000 -0.979 0.413 1 0016860 intramolecular oxidoreductase activity F 0 0 0 0 0 3 8 1 37.5 800 0.867 0.414 1 0031324 negative regulation of cellular metabolic process P 0 0 0 0 0 3 8 3 37.5 266.6667 0.867 0.416 1 0009892 negative regulation of metabolic process P 0 0 0 0 0 3 8 3 37.5 266.6667 0.867 0.416 1 0003867 4-aminobutyrate transaminase activity F 1 2 2 50 100 1 2 2 50 100 0.845 0.416 1 0004357 glutamate-cysteine ligase activity F 1 2 2 50 100 1 2 2 50 100 0.845 0.417 1 0006308 DNA catabolic process P 1 2 2 50 100 1 2 2 50 100 0.845 0.417 1 0008855 exodeoxyribonuclease VII activity F 1 2 2 50 100 1 2 2 50 100 0.845 0.417 1 0009318 exodeoxyribonuclease VII complex C 1 2 2 50 100 1 2 2 50 100 0.845 0.417 1 0016849 phosphorus-oxygen lyase activity F 0 0 0 0 0 1 2 1 50 200 0.845 0.418 1 0004615 phosphomannomutase activity F 1 2 2 50 100 1 2 2 50 100 0.845 0.419 1 0008907 integrase activity F 0 0 0 0 0 1 2 2 50 100 0.845 0.42 1 0009037 tyrosine-based site-specific recombinase activity F 1 2 2 50 100 1 2 2 50 100 0.845 0.42 1 0009009 site-specific recombinase activity F 0 0 0 0 0 1 2 2 50 100 0.845 0.42 1 0071973 bacterial-type flagellum-dependent cell motility P 3 20 20 15 100 3 20 20 15 100 -0.979 0.42 1 0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen F 0 2 2 0 100 3 8 5 37.5 160 0.867 0.421 1 0015930 glutamate synthase activity F 1 2 2 50 100 1 2 2 50 100 0.845 0.421 1 0009186 deoxyribonucleoside diphosphate metabolic process P 1 1 1 100 100 1 2 2 50 100 0.845 0.421 1 0006820 anion transport P 0 0 0 0 0 11 56 19 19.64286 294.7368 -0.832 0.421 1 0051604 protein maturation P 0 0 0 0 0 1 2 2 50 100 0.845 0.422 1 0016485 protein processing P 1 1 1 100 100 1 2 2 50 100 0.845 0.422 1 0016775 phosphotransferase activity, nitrogenous group as acceptor F 0 0 0 0 0 3 19 18 15.78947 105.5556 -0.874 0.423 1 0044461 bacterial-type flagellum part C 0 0 0 0 0 3 20 3 15 666.6667 -0.979 0.424 1 0044463 cell projection part C 0 0 0 0 0 3 20 3 15 666.6667 -0.979 0.424 1 0006270 DNA replication initiation P 1 1 1 100 100 1 2 2 50 100 0.845 0.425 1 0006275 regulation of DNA replication P 1 1 1 100 100 1 2 2 50 100 0.845 0.425 1 0008725 DNA-3-methyladenine glycosylase activity F 1 2 2 50 100 1 2 2 50 100 0.845 0.425 1 0043733 DNA-3-methylbase glycosylase activity F 0 0 0 0 0 1 2 2 50 100 0.845 0.425 1 0019364 pyridine nucleotide catabolic process P 0 0 0 0 0 1 2 2 50 100 0.845 0.426 1 0072526 pyridine-containing compound catabolic process P 0 0 0 0 0 1 2 2 50 100 0.845 0.426 1 0015969 guanosine tetraphosphate metabolic process P 1 2 2 50 100 1 2 2 50 100 0.845 0.426 1 0033735 aspartate dehydrogenase activity F 1 2 2 50 100 1 2 2 50 100 0.845 0.426 1 0034035 purine ribonucleoside bisphosphate metabolic process P 0 0 0 0 0 1 2 2 50 100 0.845 0.426 1 0006742 NADP catabolic process P 1 2 2 50 100 1 2 2 50 100 0.845 0.426 1 0045239 tricarboxylic acid cycle enzyme complex C 1 1 1 100 100 1 2 2 50 100 0.845 0.427 1 0002097 tRNA wobble base modification P 0 0 0 0 0 1 2 1 50 200 0.845 0.428 1 0030257 type III protein secretion system complex C 1 2 2 50 100 1 2 2 50 100 0.845 0.429 1 1901681 sulfur compound binding F 0 0 0 0 0 6 18 12 33.33333 150 0.889 0.43 1 0004619 phosphoglycerate mutase activity F 1 2 2 50 100 1 2 2 50 100 0.845 0.43 1 0008253 5’-nucleotidase activity F 1 2 2 50 100 1 2 2 50 100 0.845 0.431 1 0009316 3-isopropylmalate dehydratase complex C 1 2 2 50 100 1 2 2 50 100 0.845 0.431 1 0008252 nucleotidase activity F 0 1 1 0 100 1 2 2 50 100 0.845 0.431 1 0042219 cellular modified amino acid catabolic process P 0 0 0 0 0 1 2 1 50 200 0.845 0.432 1 0050096 methylaspartate ammonia-lyase activity F 1 2 2 50 100 1 2 2 50 100 0.845 0.432 1 0006570 tyrosine metabolic process P 1 1 1 100 100 1 2 1 50 200 0.845 0.432 1 0004789 thiamine-phosphate diphosphorylase activity F 1 2 2 50 100 1 2 2 50 100 0.845 0.433 1 0016434 rRNA (cytosine) methyltransferase activity F 0 0 0 0 0 1 2 1 50 200 0.845 0.433 1 0046437 D-amino acid biosynthetic process P 0 0 0 0 0 1 2 2 50 100 0.845 0.434 1 0006424 glutamyl-tRNA aminoacylation P 1 2 2 50 100 1 2 2 50 100 0.845 0.434 1 0046144 D-alanine family amino acid metabolic process P 0 0 0 0 0 1 2 2 50 100 0.845 0.434 1 0046436 D-alanine metabolic process P 0 0 0 0 0 1 2 2 50 100 0.845 0.434 1 0046416 D-amino acid metabolic process P 0 0 0 0 0 1 2 2 50 100 0.845 0.434 1 0008784 alanine racemase activity F 1 2 2 50 100 1 2 2 50 100 0.845 0.434 1 0046145 D-alanine family amino acid biosynthetic process P 0 0 0 0 0 1 2 2 50 100 0.845 0.434 1 0030632 D-alanine biosynthetic process P 1 2 2 50 100 1 2 2 50 100 0.845 0.434 1 0042182 ketone catabolic process P 0 0 0 0 0 1 2 1 50 200 0.845 0.434 1 0097159 organic cyclic compound binding F 0 0 0 0 0 215 917 28 23.44602 3275 -0.802 0.434 1 1901363 heterocyclic compound binding F 0 0 0 0 0 215 917 28 23.44602 3275 -0.802 0.434 1 0042398 cellular modified amino acid biosynthetic process P 1 2 2 50 100 3 20 6 15 333.3333 -0.979 0.435 1 0010038 response to metal ion P 1 2 2 50 100 1 2 2 50 100 0.845 0.436 1 0070403 NAD+ binding F 1 2 2 50 100 1 2 2 50 100 0.845 0.437 1 0004061 arylformamidase activity F 1 2 2 50 100 1 2 2 50 100 0.845 0.437 1 0051186 cofactor metabolic process P 0 0 0 0 0 22 106 6 20.75472 1766.667 -0.883 0.438 1 0004029 aldehyde dehydrogenase (NAD) activity F 1 2 2 50 100 1 2 2 50 100 0.845 0.439 1 0008815 citrate (pro-3S)-lyase activity F 1 2 2 50 100 1 2 2 50 100 0.845 0.439 1 0018454 acetoacetyl-CoA reductase activity F 1 2 2 50 100 1 2 2 50 100 0.845 0.44 1 0004328 formamidase activity F 1 2 2 50 100 1 2 2 50 100 0.845 0.441 1 0004872 receptor activity F 4 15 15 26.66667 100 7 38 33 18.42105 115.1515 -0.86 0.441 1 0003942 N-acetyl-gamma-glutamyl-phosphate reductase activity F 1 2 2 50 100 1 2 2 50 100 0.845 0.442 1 0008963 phospho-N-acetylmuramoyl-pentapeptide-transferase activity F 1 2 2 50 100 1 2 2 50 100 0.845 0.443 1 0006545 glycine biosynthetic process P 1 2 2 50 100 1 2 2 50 100 0.845 0.444 1 0009404 toxin metabolic process P 0 1 1 0 100 1 2 2 50 100 0.845 0.444 1 0006767 water-soluble vitamin metabolic process P 0 0 0 0 0 6 33 5 18.18182 660 -0.832 0.444 1 0006766 vitamin metabolic process P 0 0 0 0 0 6 33 5 18.18182 660 -0.832 0.444 1 0046907 intracellular transport P 0 0 0 0 0 1 9 9 11.11111 100 -0.928 0.444 1 0006605 protein targeting P 1 7 7 14.28571 100 1 9 9 11.11111 100 -0.928 0.444 1 0006886 intracellular protein transport P 0 4 4 0 100 1 9 9 11.11111 100 -0.928 0.444 1 1902582 single-organism intracellular transport P 0 0 0 0 0 1 9 9 11.11111 100 -0.928 0.444 1 0019899 enzyme binding F 0 0 0 0 0 1 2 2 50 100 0.845 0.445 1 0070063 RNA polymerase binding F 1 2 2 50 100 1 2 2 50 100 0.845 0.445 1 0030955 potassium ion binding F 1 2 2 50 100 1 2 2 50 100 0.845 0.445 1 0031420 alkali metal ion binding F 0 0 0 0 0 1 2 2 50 100 0.845 0.445 1 0003906 DNA-(apurinic or apyrimidinic site) lyase activity F 1 2 2 50 100 1 2 2 50 100 0.845 0.446 1 0098797 plasma membrane protein complex C 0 0 0 0 0 12 41 37 29.26829 110.8108 0.737 0.447 1 0004520 endodeoxyribonuclease activity F 0 1 1 0 100 1 9 5 11.11111 180 -0.928 0.447 1 0042927 siderophore transporter activity F 0 0 0 0 0 1 2 2 50 100 0.845 0.448 1 0015603 iron chelate transmembrane transporter activity F 0 0 0 0 0 1 2 2 50 100 0.845 0.448 1 0015343 siderophore transmembrane transporter activity F 1 2 2 50 100 1 2 2 50 100 0.845 0.448 1 0044718 siderophore transmembrane transport P 1 2 2 50 100 1 2 2 50 100 0.845 0.448 1 0008972 phosphomethylpyrimidine kinase activity F 1 2 2 50 100 1 2 2 50 100 0.845 0.448 1 0006081 cellular aldehyde metabolic process P 0 0 0 0 0 3 20 5 15 400 -0.979 0.448 1 0046075 dTTP metabolic process P 0 0 0 0 0 1 2 2 50 100 0.845 0.449 1 0006235 dTTP biosynthetic process P 1 2 2 50 100 1 2 2 50 100 0.845 0.449 1 0004160 dihydroxy-acid dehydratase activity F 1 2 2 50 100 1 2 2 50 100 0.845 0.449 1 0022836 gated channel activity F 0 0 0 0 0 1 2 1 50 200 0.845 0.45 1 1902589 single-organism organelle organization P 0 0 0 0 0 3 19 1 15.78947 1900 -0.874 0.451 1 0046112 nucleobase biosynthetic process P 0 0 0 0 0 1 10 6 10 166.6667 -1.06 0.454 1 0016413 O-acetyltransferase activity F 0 0 0 0 0 1 2 1 50 200 0.845 0.455 1 0015794 glycerol-3-phosphate transport P 1 2 2 50 100 1 2 2 50 100 0.845 0.455 1 0001407 glycerophosphodiester transport P 1 2 2 50 100 1 2 2 50 100 0.845 0.455 1 0004739 pyruvate dehydrogenase (acetyl-transferring) activity F 1 2 2 50 100 1 2 2 50 100 0.845 0.456 1 0004738 pyruvate dehydrogenase activity F 0 0 0 0 0 1 2 2 50 100 0.845 0.456 1 0006650 glycerophospholipid metabolic process P 0 1 1 0 100 1 9 4 11.11111 225 -0.928 0.457 1 0046486 glycerolipid metabolic process P 0 0 0 0 0 1 9 4 11.11111 225 -0.928 0.457 1 0046914 transition metal ion binding F 0 0 0 0 0 28 130 9 21.53846 1444.444 -0.77 0.461 1 0006541 glutamine metabolic process P 1 8 8 12.5 100 1 9 9 11.11111 100 -0.928 0.461 1 0046487 glyoxylate metabolic process P 0 0 0 0 0 1 2 2 50 100 0.845 0.462 1 0006097 glyoxylate cycle P 1 2 2 50 100 1 2 2 50 100 0.845 0.462 1 0006754 ATP biosynthetic process P 1 8 8 12.5 100 1 9 9 11.11111 100 -0.928 0.462 1 0009108 coenzyme biosynthetic process P 0 0 0 0 0 18 63 6 28.57143 1050 0.787 0.463 1 0008643 carbohydrate transport P 1 4 4 25 100 1 9 6 11.11111 150 -0.928 0.464 1 0005507 copper ion binding F 1 9 9 11.11111 100 1 9 9 11.11111 100 -0.928 0.469 1 0009331 glycerol-3-phosphate dehydrogenase complex C 1 2 2 50 100 1 2 2 50 100 0.845 0.47 1 0044550 secondary metabolite biosynthetic process P 0 0 0 0 0 1 2 1 50 200 0.845 0.47 1 0006783 heme biosynthetic process P 0 3 3 0 100 1 9 7 11.11111 128.5714 -0.928 0.471 1 0033036 macromolecule localization P 0 0 0 0 0 19 67 43 28.35821 155.8139 0.771 0.472 1 0000270 peptidoglycan metabolic process P 0 1 1 0 100 4 24 18 16.66667 133.3333 -0.882 0.472 1 0030203 glycosaminoglycan metabolic process P 0 0 0 0 0 4 24 18 16.66667 133.3333 -0.882 0.472 1 0006022 aminoglycan metabolic process P 0 0 0 0 0 4 24 18 16.66667 133.3333 -0.882 0.472 1 0042168 heme metabolic process P 0 1 1 0 100 1 10 8 10 125 -1.06 0.474 1 0006730 one-carbon metabolic process P 1 8 8 12.5 100 1 9 9 11.11111 100 -0.928 0.476 1 0046653 tetrahydrofolate metabolic process P 0 3 3 0 100 1 10 6 10 166.6667 -1.06 0.477 1 0030031 cell projection assembly P 0 0 0 0 0 1 9 9 11.11111 100 -0.928 0.478 1 0044780 bacterial-type flagellum assembly P 1 8 8 12.5 100 1 9 9 11.11111 100 -0.928 0.478 1 0031226 intrinsic component of plasma membrane C 0 1 1 0 100 4 23 22 17.3913 104.5455 -0.782 0.481 1 0009145 purine nucleoside triphosphate biosynthetic process P 0 0 0 0 0 1 10 9 10 111.1111 -1.06 0.481 1 0009206 purine ribonucleoside triphosphate biosynthetic process P 0 0 0 0 0 1 10 9 10 111.1111 -1.06 0.481 1 0090529 cell septum assembly P 0 0 0 0 0 1 10 9 10 111.1111 -1.06 0.482 1 0032506 cytokinetic process P 0 0 0 0 0 1 10 9 10 111.1111 -1.06 0.482 1 1902410 mitotic cytokinetic process P 0 0 0 0 0 1 10 9 10 111.1111 -1.06 0.482 1 0061640 cytoskeleton-dependent cytokinesis P 0 0 0 0 0 1 10 9 10 111.1111 -1.06 0.482 1 0000278 mitotic cell cycle P 0 0 0 0 0 1 10 9 10 111.1111 -1.06 0.482 1 1903047 mitotic cell cycle process P 0 0 0 0 0 1 10 9 10 111.1111 -1.06 0.482 1 0000281 mitotic cytokinesis P 0 0 0 0 0 1 10 9 10 111.1111 -1.06 0.482 1 0000917 barrier septum assembly P 1 8 8 12.5 100 1 10 9 10 111.1111 -1.06 0.482 1 0044822 poly(A) RNA binding F 0 0 0 0 0 1 2 2 50 100 0.845 0.485 1 0003729 mRNA binding F 1 2 2 50 100 1 2 2 50 100 0.845 0.485 1 0046364 monosaccharide biosynthetic process P 0 0 0 0 0 1 9 7 11.11111 128.5714 -0.928 0.485 1 0005996 monosaccharide metabolic process P 0 0 0 0 0 1 10 8 10 125 -1.06 0.487 1 0000996 core DNA-dependent RNA polymerase binding promoter specificity activity F 0 0 0 0 0 4 12 12 33.33333 100 0.725 0.495 1 0016987 sigma factor activity F 4 12 12 33.33333 100 4 12 12 33.33333 100 0.725 0.495 1 0006352 DNA-templated transcription, initiation P 4 12 12 33.33333 100 4 12 12 33.33333 100 0.725 0.495 1 0000990 transcription factor activity, core RNA polymerase binding F 0 0 0 0 0 4 12 12 33.33333 100 0.725 0.495 1 0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity F 0 0 0 0 0 8 43 16 18.60465 268.75 -0.887 0.496 1 0015399 primary active transmembrane transporter activity F 0 0 0 0 0 8 43 16 18.60465 268.75 -0.887 0.496 1 1901663 quinone biosynthetic process P 0 0 0 0 0 1 9 9 11.11111 100 -0.928 0.496 1 1901661 quinone metabolic process P 0 0 0 0 0 1 9 9 11.11111 100 -0.928 0.496 1 0006743 ubiquinone metabolic process P 0 0 0 0 0 1 9 9 11.11111 100 -0.928 0.496 1 0006744 ubiquinone biosynthetic process P 1 9 9 11.11111 100 1 9 9 11.11111 100 -0.928 0.496 1 0072527 pyrimidine-containing compound metabolic process P 0 0 0 0 0 5 27 9 18.51852 300 -0.711 0.499 1 0042181 ketone biosynthetic process P 0 0 0 0 0 1 10 9 10 111.1111 -1.06 0.504 1 0006790 sulfur compound metabolic process P 0 0 0 0 0 8 42 8 19.04762 525 -0.809 0.51 1 0016638 oxidoreductase activity, acting on the CH-NH2 group of donors F 1 3 3 33.33333 100 4 12 8 33.33333 150 0.725 0.515 1 0034613 cellular protein localization P 0 0 0 0 0 2 14 5 14.28571 280 -0.881 0.515 1 0070727 cellular macromolecule localization P 0 0 0 0 0 2 14 5 14.28571 280 -0.881 0.515 1 1901606 alpha-amino acid catabolic process P 0 0 0 0 0 4 12 4 33.33333 300 0.725 0.517 1 0004536 deoxyribonuclease activity F 0 1 1 0 100 2 13 6 15.38461 216.6667 -0.756 0.521 1 1901605 alpha-amino acid metabolic process P 0 0 0 0 0 24 112 8 21.42857 1400 -0.739 0.523 1 0050661 NADP binding F 2 13 13 15.38461 100 2 14 14 14.28571 100 -0.881 0.523 1 0020037 heme binding F 5 28 28 17.85714 100 5 28 28 17.85714 100 -0.806 0.525 1 0009082 branched-chain amino acid biosynthetic process P 2 13 13 15.38461 100 2 14 14 14.28571 100 -0.881 0.525 1 0042886 amide transport P 0 0 0 0 0 4 11 9 36.36364 122.2222 0.929 0.526 1 0006733 oxidoreduction coenzyme metabolic process P 0 0 0 0 0 10 33 13 30.30303 253.8462 0.8 0.526 1 0046872 metal ion binding F 56 271 271 20.66421 100 76 332 277 22.89157 119.8556 -0.669 0.526 1 0016597 amino acid binding F 2 13 13 15.38461 100 2 13 13 15.38461 100 -0.756 0.526 1 0043169 cation binding F 0 5 5 0 100 78 340 282 22.94118 120.5674 -0.655 0.527 1 0007155 cell adhesion P 4 12 12 33.33333 100 4 12 12 33.33333 100 0.725 0.528 1 0022610 biological adhesion P 0 0 0 0 0 4 12 12 33.33333 100 0.725 0.528 1 0016052 carbohydrate catabolic process P 0 0 0 0 0 2 14 12 14.28571 116.6667 -0.881 0.533 1 0044724 single-organism carbohydrate catabolic process P 0 0 0 0 0 2 14 12 14.28571 116.6667 -0.881 0.533 1 0043648 dicarboxylic acid metabolic process P 0 0 0 0 0 9 30 8 30 375 0.723 0.536 1 0008115 sarcosine oxidase activity F 0 4 4 0 100 0 4 4 0 100 -1.136 0.538 1 0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor F 0 0 0 0 0 0 4 4 0 100 -1.136 0.538 1 0006165 nucleoside diphosphate phosphorylation P 0 1 1 0 100 2 13 13 15.38461 100 -0.756 0.543 1 0009069 serine family amino acid metabolic process P 0 0 0 0 0 2 13 3 15.38461 433.3333 -0.756 0.544 1 0045263 proton-transporting ATP synthase complex, coupling factor F(o) C 0 3 3 0 100 0 3 3 0 100 -0.983 0.546 1 0033177 proton-transporting two-sector ATPase complex, proton-transporting domain C 0 1 1 0 100 0 3 3 0 100 -0.983 0.546 1 0044272 sulfur compound biosynthetic process P 0 0 0 0 0 6 32 8 18.75 400 -0.744 0.547 1 0004148 dihydrolipoyl dehydrogenase activity F 0 3 3 0 100 0 3 3 0 100 -0.983 0.548 1 0015711 organic anion transport P 0 0 0 0 0 7 36 19 19.44444 189.4737 -0.692 0.549 1 0009110 vitamin biosynthetic process P 0 0 0 0 0 6 32 5 18.75 640 -0.744 0.55 1 0042364 water-soluble vitamin biosynthetic process P 0 0 0 0 0 6 32 5 18.75 640 -0.744 0.55 1 0000104 succinate dehydrogenase activity F 0 2 2 0 100 0 4 4 0 100 -1.136 0.55 1 0009289 pilus C 0 4 4 0 100 0 4 4 0 100 -1.136 0.552 1 0009381 excinuclease ABC activity F 0 4 4 0 100 0 4 4 0 100 -1.136 0.555 1 0043952 protein transport by the Sec complex P 0 3 3 0 100 0 3 3 0 100 -0.983 0.557 1 0008194 UDP-glycosyltransferase activity F 0 0 0 0 0 0 3 2 0 150 -0.983 0.558 1 0070569 uridylyltransferase activity F 0 0 0 0 0 0 3 1 0 300 -0.983 0.559 1 0005315 inorganic phosphate transmembrane transporter activity F 0 4 4 0 100 0 4 4 0 100 -1.136 0.559 1 0071822 protein complex subunit organization P 0 0 0 0 0 5 15 4 33.33333 375 0.811 0.56 1 0035435 phosphate ion transmembrane transport P 0 3 3 0 100 0 3 3 0 100 -0.983 0.561 1 0043244 regulation of protein complex disassembly P 0 0 0 0 0 0 3 2 0 150 -0.983 0.562 1 0061505 DNA topoisomerase II activity F 0 0 0 0 0 0 4 4 0 100 -1.136 0.563 1 0006144 purine nucleobase metabolic process P 0 1 1 0 100 0 4 4 0 100 -1.136 0.563 1 0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity F 0 4 4 0 100 0 4 4 0 100 -1.136 0.563 1 0016405 CoA-ligase activity F 0 0 0 0 0 0 3 2 0 150 -0.983 0.564 1 0015293 symporter activity F 0 0 0 0 0 0 3 1 0 300 -0.983 0.566 1 0019825 oxygen binding F 0 4 4 0 100 0 4 4 0 100 -1.136 0.566 1 0061695 transferase complex, transferring phosphorus-containing groups C 0 0 0 0 0 0 4 3 0 133.3333 -1.136 0.566 1 0098656 anion transmembrane transport P 0 0 0 0 0 6 19 10 31.57895 190 0.735 0.567 1 0016417 S-acyltransferase activity F 0 0 0 0 0 0 3 1 0 300 -0.983 0.567 1 0016433 rRNA (adenine) methyltransferase activity F 0 1 1 0 100 0 3 1 0 300 -0.983 0.567 1 0015718 monocarboxylic acid transport P 0 0 0 0 0 0 3 1 0 300 -0.983 0.567 1 0044427 chromosomal part C 0 0 0 0 0 0 4 4 0 100 -1.136 0.567 1 0032993 protein-DNA complex C 0 0 0 0 0 0 4 4 0 100 -1.136 0.567 1 0005657 replication fork C 0 0 0 0 0 0 4 4 0 100 -1.136 0.567 1 1990077 primosome complex C 0 4 4 0 100 0 4 4 0 100 -1.136 0.567 1 0006269 DNA replication, synthesis of RNA primer P 0 4 4 0 100 0 4 4 0 100 -1.136 0.567 1 0030894 replisome C 0 1 1 0 100 0 4 4 0 100 -1.136 0.567 1 0008410 CoA-transferase activity F 2 5 5 40 100 2 5 5 40 100 0.815 0.568 1 0009088 threonine biosynthetic process P 0 3 3 0 100 0 3 3 0 100 -0.983 0.568 1 0065002 intracellular protein transmembrane transport P 0 4 4 0 100 0 4 4 0 100 -1.136 0.568 1 0035999 tetrahydrofolate interconversion P 0 4 4 0 100 0 4 4 0 100 -1.136 0.568 1 0009262 deoxyribonucleotide metabolic process P 0 0 0 0 0 2 5 1 40 500 0.815 0.569 1 0019646 aerobic electron transport chain P 0 3 3 0 100 0 3 3 0 100 -0.983 0.569 1 0009113 purine nucleobase biosynthetic process P 0 2 2 0 100 0 3 3 0 100 -0.983 0.569 1 0015920 lipopolysaccharide transport P 0 3 3 0 100 0 3 3 0 100 -0.983 0.57 1 0006084 acetyl-CoA metabolic process P 0 1 1 0 100 0 4 3 0 133.3333 -1.136 0.57 1 0016757 transferase activity, transferring glycosyl groups F 3 29 29 10.34483 100 7 35 31 20 112.9032 -0.605 0.571 1 0008948 oxaloacetate decarboxylase activity F 0 3 3 0 100 0 3 3 0 100 -0.983 0.571 1 0003994 aconitate hydratase activity F 0 3 3 0 100 0 3 3 0 100 -0.983 0.571 1 0004473 malate dehydrogenase (decarboxylating) (NADP+) activity F 0 3 3 0 100 0 3 3 0 100 -0.983 0.571 1 0004471 malate dehydrogenase (decarboxylating) (NAD+) activity F 0 3 3 0 100 0 3 3 0 100 -0.983 0.571 1 0016149 translation release factor activity, codon specific F 0 3 3 0 100 0 3 3 0 100 -0.983 0.571 1 0004470 malic enzyme activity F 0 0 0 0 0 0 3 3 0 100 -0.983 0.571 1 0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity F 0 4 4 0 100 0 4 4 0 100 -1.136 0.571 1 0008079 translation termination factor activity F 0 0 0 0 0 0 4 4 0 100 -1.136 0.571 1 0003747 translation release factor activity F 0 3 3 0 100 0 4 4 0 100 -1.136 0.571 1 0016891 endoribonuclease activity, producing 5’-phosphomonoesters F 0 0 0 0 0 0 4 2 0 200 -1.136 0.572 1 0090662 ATP hydrolysis coupled transmembrane transport P 0 0 0 0 0 0 3 3 0 100 -0.983 0.573 1 0015991 ATP hydrolysis coupled proton transport P 0 3 3 0 100 0 3 3 0 100 -0.983 0.573 1 0042575 DNA polymerase complex C 0 0 0 0 0 0 3 3 0 100 -0.983 0.573 1 0009360 DNA polymerase III complex C 0 3 3 0 100 0 3 3 0 100 -0.983 0.573 1 0009401 phosphoenolpyruvate-dependent sugar phosphotransferase system P 0 3 3 0 100 0 3 3 0 100 -0.983 0.573 1 1990391 DNA repair complex C 0 0 0 0 0 0 3 3 0 100 -0.983 0.574 1 0009095 aromatic amino acid family biosynthetic process, prephenate pathway P 0 0 0 0 0 0 3 2 0 150 -0.983 0.574 1 0009380 excinuclease repair complex C 0 3 3 0 100 0 3 3 0 100 -0.983 0.574 1 0006564 L-serine biosynthetic process P 0 3 3 0 100 0 3 3 0 100 -0.983 0.574 1 0006353 DNA-templated transcription, termination P 0 4 4 0 100 0 4 4 0 100 -1.136 0.574 1 0006098 pentose-phosphate shunt P 0 4 4 0 100 0 4 4 0 100 -1.136 0.575 1 0044087 regulation of cellular component biogenesis P 0 0 0 0 0 0 4 1 0 400 -1.136 0.576 1 1901616 organic hydroxy compound catabolic process P 0 0 0 0 0 0 4 1 0 400 -1.136 0.577 1 0004527 exonuclease activity F 2 11 11 18.18182 100 3 18 16 16.66667 112.5 -0.763 0.578 1 0070525 tRNA threonylcarbamoyladenosine metabolic process P 0 0 0 0 0 0 3 3 0 100 -0.983 0.578 1 0002949 tRNA threonylcarbamoyladenosine modification P 0 3 3 0 100 0 3 3 0 100 -0.983 0.578 1 0051248 negative regulation of protein metabolic process P 0 0 0 0 0 0 3 1 0 300 -0.983 0.579 1 0046036 CTP metabolic process P 0 0 0 0 0 0 3 3 0 100 -0.983 0.579 1 0032269 negative regulation of cellular protein metabolic process P 0 0 0 0 0 0 3 1 0 300 -0.983 0.579 1 0006241 CTP biosynthetic process P 0 1 1 0 100 0 3 3 0 100 -0.983 0.579 1 0009208 pyrimidine ribonucleoside triphosphate metabolic process P 0 0 0 0 0 0 3 3 0 100 -0.983 0.579 1 0016842 amidine-lyase activity F 0 0 0 0 0 0 3 1 0 300 -0.983 0.579 1 0009209 pyrimidine ribonucleoside triphosphate biosynthetic process P 0 0 0 0 0 0 3 3 0 100 -0.983 0.579 1 0033281 TAT protein transport complex C 0 3 3 0 100 0 3 3 0 100 -0.983 0.58 1 0043953 protein transport by the Tat complex P 0 3 3 0 100 0 3 3 0 100 -0.983 0.58 1 0046164 alcohol catabolic process P 0 0 0 0 0 0 3 1 0 300 -0.983 0.58 1 0042274 ribosomal small subunit biogenesis P 0 3 3 0 100 0 3 3 0 100 -0.983 0.58 1 0019751 polyol metabolic process P 0 0 0 0 0 0 3 1 0 300 -0.983 0.58 1 0046174 polyol catabolic process P 0 0 0 0 0 0 3 1 0 300 -0.983 0.58 1 0006566 threonine metabolic process P 0 0 0 0 0 0 4 3 0 133.3333 -1.136 0.58 1 0071616 acyl-CoA biosynthetic process P 0 0 0 0 0 0 4 2 0 200 -1.136 0.581 1 0035384 thioester biosynthetic process P 0 0 0 0 0 0 4 2 0 200 -1.136 0.581 1 0003697 single-stranded DNA binding F 0 4 4 0 100 0 4 4 0 100 -1.136 0.581 1 0019740 nitrogen utilization P 0 0 0 0 0 0 4 4 0 100 -1.136 0.581 1 0006808 regulation of nitrogen utilization P 0 4 4 0 100 0 4 4 0 100 -1.136 0.581 1 1903508 positive regulation of nucleic acid-templated transcription P 0 0 0 0 0 2 5 5 40 100 0.815 0.582 1 0045935 positive regulation of nucleobase-containing compound metabolic process P 0 0 0 0 0 2 5 5 40 100 0.815 0.582 1 0051254 positive regulation of RNA metabolic process P 0 0 0 0 0 2 5 5 40 100 0.815 0.582 1 1902680 positive regulation of RNA biosynthetic process P 0 0 0 0 0 2 5 5 40 100 0.815 0.582 1 0045893 positive regulation of transcription, DNA-templated P 2 5 5 40 100 2 5 5 40 100 0.815 0.582 1 0050897 cobalt ion binding F 0 4 4 0 100 0 4 4 0 100 -1.136 0.582 1 0019239 deaminase activity F 0 1 1 0 100 0 4 2 0 200 -1.136 0.582 1 0008186 RNA-dependent ATPase activity F 0 1 1 0 100 0 3 3 0 100 -0.983 0.583 1 0010340 carboxyl-O-methyltransferase activity F 0 1 1 0 100 0 3 3 0 100 -0.983 0.583 1 0042255 ribosome assembly P 0 1 1 0 100 0 3 2 0 150 -0.983 0.583 1 0071826 ribonucleoprotein complex subunit organization P 0 0 0 0 0 0 3 1 0 300 -0.983 0.583 1 0022618 ribonucleoprotein complex assembly P 0 0 0 0 0 0 3 1 0 300 -0.983 0.583 1 0019213 deacetylase activity F 0 0 0 0 0 0 4 2 0 200 -1.136 0.583 1 0000155 phosphorelay sensor kinase activity F 3 18 18 16.66667 100 3 18 18 16.66667 100 -0.763 0.584 1 0023014 signal transduction by protein phosphorylation P 3 18 18 16.66667 100 3 18 18 16.66667 100 -0.763 0.584 1 0004673 protein histidine kinase activity F 0 6 6 0 100 3 18 18 16.66667 100 -0.763 0.584 1 0019202 amino acid kinase activity F 0 0 0 0 0 0 3 1 0 300 -0.983 0.585 1 0000156 phosphorelay response regulator activity F 0 3 3 0 100 0 3 3 0 100 -0.983 0.585 1 0042822 pyridoxal phosphate metabolic process P 0 0 0 0 0 2 5 5 40 100 0.815 0.586 1 0042823 pyridoxal phosphate biosynthetic process P 1 4 4 25 100 2 5 5 40 100 0.815 0.586 1 0004674 protein serine/threonine kinase activity F 0 3 3 0 100 0 3 3 0 100 -0.983 0.586 1 1901070 guanosine-containing compound biosynthetic process P 0 0 0 0 0 0 3 2 0 150 -0.983 0.586 1 0006108 malate metabolic process P 0 4 4 0 100 0 4 4 0 100 -1.136 0.586 1 0070567 cytidylyltransferase activity F 0 0 0 0 0 0 4 1 0 400 -1.136 0.586 1 0090503 RNA phosphodiester bond hydrolysis, exonucleolytic P 0 3 3 0 100 0 3 3 0 100 -0.983 0.589 1 0016896 exoribonuclease activity, producing 5’-phosphomonoesters F 0 1 1 0 100 0 3 2 0 150 -0.983 0.589 1 0004532 exoribonuclease activity F 0 0 0 0 0 0 3 2 0 150 -0.983 0.589 1 0004616 phosphogluconate dehydrogenase (decarboxylating) activity F 0 4 4 0 100 0 4 4 0 100 -1.136 0.589 1 0006040 amino sugar metabolic process P 0 1 1 0 100 0 4 3 0 133.3333 -1.136 0.589 1 0043094 cellular metabolic compound salvage P 0 0 0 0 0 2 5 3 40 166.6667 0.815 0.59 1 0009317 acetyl-CoA carboxylase complex C 0 4 4 0 100 0 4 4 0 100 -1.136 0.59 1 0003989 acetyl-CoA carboxylase activity F 0 4 4 0 100 0 4 4 0 100 -1.136 0.59 1 0015662 ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism F 0 0 0 0 0 0 3 3 0 100 -0.983 0.591 1 0006546 glycine catabolic process P 0 2 2 0 100 0 3 3 0 100 -0.983 0.591 1 0019464 glycine decarboxylation via glycine cleavage system P 0 3 3 0 100 0 3 3 0 100 -0.983 0.591 1 0008556 potassium-transporting ATPase activity F 0 3 3 0 100 0 3 3 0 100 -0.983 0.591 1 0009071 serine family amino acid catabolic process P 0 0 0 0 0 0 3 3 0 100 -0.983 0.591 1 0055129 L-proline biosynthetic process P 0 4 4 0 100 0 4 4 0 100 -1.136 0.591 1 0009295 nucleoid C 0 3 3 0 100 0 3 3 0 100 -0.983 0.592 1 0016071 mRNA metabolic process P 0 0 0 0 0 0 4 2 0 200 -1.136 0.592 1 0016725 oxidoreductase activity, acting on CH or CH2 groups F 0 0 0 0 0 2 5 2 40 250 0.815 0.594 1 0006323 DNA packaging P 0 0 0 0 0 0 3 3 0 100 -0.983 0.594 1 0030261 chromosome condensation P 0 3 3 0 100 0 3 3 0 100 -0.983 0.594 1 0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor F 0 0 0 0 0 0 3 1 0 300 -0.983 0.594 1 0009254 peptidoglycan turnover P 0 4 4 0 100 0 4 4 0 100 -1.136 0.594 1 0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity F 0 3 3 0 100 0 3 3 0 100 -0.983 0.595 1 0006026 aminoglycan catabolic process P 0 0 0 0 0 2 5 5 40 100 0.815 0.596 1 0009253 peptidoglycan catabolic process P 2 5 5 40 100 2 5 5 40 100 0.815 0.596 1 0008745 N-acetylmuramoyl-L-alanine amidase activity F 2 5 5 40 100 2 5 5 40 100 0.815 0.596 1 0006027 glycosaminoglycan catabolic process P 0 0 0 0 0 2 5 5 40 100 0.815 0.596 1 0043492 ATPase activity, coupled to movement of substances F 0 0 0 0 0 8 39 16 20.51282 243.75 -0.564 0.596 1 0042626 ATPase activity, coupled to transmembrane movement of substances F 2 10 10 20 100 8 39 16 20.51282 243.75 -0.564 0.596 1 1901505 carbohydrate derivative transporter activity F 0 0 0 0 0 0 3 1 0 300 -0.983 0.596 1 0016832 aldehyde-lyase activity F 0 1 1 0 100 0 4 2 0 200 -1.136 0.596 1 0006470 protein dephosphorylation P 0 4 4 0 100 0 4 4 0 100 -1.136 0.597 1 0072593 reactive oxygen species metabolic process P 0 0 0 0 0 2 5 1 40 500 0.815 0.598 1 0060089 molecular transducer activity F 0 0 0 0 0 9 44 26 20.45455 169.2308 -0.609 0.598 1 0071554 cell wall organization or biogenesis P 0 0 0 0 0 3 17 17 17.64706 100 -0.647 0.598 1 0034308 primary alcohol metabolic process P 0 0 0 0 0 0 3 1 0 300 -0.983 0.598 1 0042357 thiamine diphosphate metabolic process P 0 0 0 0 0 0 4 4 0 100 -1.136 0.598 1 0009229 thiamine diphosphate biosynthetic process P 0 4 4 0 100 0 4 4 0 100 -1.136 0.598 1 0098562 cytoplasmic side of membrane C 0 0 0 0 0 0 3 3 0 100 -0.983 0.599 1 0098552 side of membrane C 0 0 0 0 0 0 3 3 0 100 -0.983 0.599 1 0009898 cytoplasmic side of plasma membrane C 0 2 2 0 100 0 3 3 0 100 -0.983 0.599 1 0006413 translational initiation P 2 5 5 40 100 2 5 5 40 100 0.815 0.6 1 0046854 phosphatidylinositol phosphorylation P 0 3 3 0 100 0 3 3 0 100 -0.983 0.6 1 0046488 phosphatidylinositol metabolic process P 0 0 0 0 0 0 3 3 0 100 -0.983 0.6 1 0004721 phosphoprotein phosphatase activity F 0 2 2 0 100 0 3 3 0 100 -0.983 0.6 1 0046834 lipid phosphorylation P 0 0 0 0 0 0 3 3 0 100 -0.983 0.6 1 0010467 gene expression P 0 0 0 0 0 100 427 275 23.4192 155.2727 -0.497 0.603 1 0009426 bacterial-type flagellum basal body, distal rod C 0 1 1 0 100 0 3 2 0 150 -0.983 0.603 1 0006304 DNA modification P 0 0 0 0 0 0 3 2 0 150 -0.983 0.603 1 0032196 transposition P 0 0 0 0 0 2 5 13 40 38.46154 0.815 0.604 1 0006313 transposition, DNA-mediated P 2 5 13 40 38.46154 2 5 13 40 38.46154 0.815 0.604 1 0006536 glutamate metabolic process P 0 0 0 0 0 2 5 4 40 125 0.815 0.605 1 0009013 succinate-semialdehyde dehydrogenase [NAD(P)+] activity F 0 3 3 0 100 0 3 3 0 100 -0.983 0.605 1 0010629 negative regulation of gene expression P 0 0 0 0 0 2 5 3 40 166.6667 0.815 0.606 1 0030488 tRNA methylation P 0 3 3 0 100 0 3 3 0 100 -0.983 0.608 1 0008484 sulfuric ester hydrolase activity F 0 4 4 0 100 0 4 4 0 100 -1.136 0.609 1 0008270 zinc ion binding F 10 48 49 20.83333 97.95918 10 48 49 20.83333 97.95918 -0.575 0.61 1 0016887 ATPase activity F 26 100 100 26 100 30 135 110 22.22222 122.7273 -0.595 0.611 1 0016841 ammonia-lyase activity F 0 0 0 0 0 2 5 2 40 250 0.815 0.612 1 0004326 tetrahydrofolylpolyglutamate synthase activity F 0 4 4 0 100 0 4 4 0 100 -1.136 0.612 1 0046900 tetrahydrofolylpolyglutamate metabolic process P 0 0 0 0 0 0 4 4 0 100 -1.136 0.612 1 0046901 tetrahydrofolylpolyglutamate biosynthetic process P 0 4 4 0 100 0 4 4 0 100 -1.136 0.612 1 0009117 nucleotide metabolic process P 0 4 4 0 100 20 92 23 21.73913 400 -0.597 0.613 1 0006479 protein methylation P 0 4 4 0 100 0 4 4 0 100 -1.136 0.613 1 0008213 protein alkylation P 0 0 0 0 0 0 4 4 0 100 -1.136 0.613 1 0008276 protein methyltransferase activity F 0 2 2 0 100 0 4 4 0 100 -1.136 0.613 1 0009084 glutamine family amino acid biosynthetic process P 0 0 0 0 0 7 24 13 29.16667 184.6154 0.55 0.618 1 0042954 lipoprotein transporter activity F 0 3 3 0 100 0 3 3 0 100 -0.983 0.618 1 0044872 lipoprotein localization P 0 0 0 0 0 0 3 3 0 100 -0.983 0.618 1 0042953 lipoprotein transport P 0 3 3 0 100 0 3 3 0 100 -0.983 0.618 1 0071705 nitrogen compound transport P 0 0 0 0 0 10 48 19 20.83333 252.6316 -0.575 0.626 1 1901607 alpha-amino acid biosynthetic process P 0 0 0 0 0 19 88 8 21.59091 1100 -0.616 0.627 1 0051172 negative regulation of nitrogen compound metabolic process P 0 0 0 0 0 2 6 3 33.33333 200 0.512 0.628 1 2000113 negative regulation of cellular macromolecule biosynthetic process P 0 0 0 0 0 2 6 3 33.33333 200 0.512 0.628 1 0009890 negative regulation of biosynthetic process P 0 0 0 0 0 2 6 3 33.33333 200 0.512 0.628 1 0031327 negative regulation of cellular biosynthetic process P 0 0 0 0 0 2 6 3 33.33333 200 0.512 0.628 1 0010558 negative regulation of macromolecule biosynthetic process P 0 0 0 0 0 2 6 3 33.33333 200 0.512 0.628 1 0008565 protein transporter activity F 3 11 11 27.27273 100 3 18 16 16.66667 112.5 -0.763 0.63 1 0046184 aldehyde biosynthetic process P 0 0 0 0 0 2 6 5 33.33333 120 0.512 0.631 1 0016878 acid-thiol ligase activity F 0 0 0 0 0 2 6 1 33.33333 600 0.512 0.633 1 0007165 signal transduction P 4 25 25 16 100 11 52 52 21.15385 100 -0.545 0.634 1 0023052 signaling P 0 0 0 0 0 11 52 52 21.15385 100 -0.545 0.634 1 0044700 single organism signaling P 0 0 0 0 0 11 52 52 21.15385 100 -0.545 0.634 1 0072528 pyrimidine-containing compound biosynthetic process P 0 0 0 0 0 5 26 9 19.23077 288.8889 -0.613 0.637 1 0090304 nucleic acid metabolic process P 0 0 0 0 0 112 442 276 25.33937 160.1449 0.523 0.639 1 0042578 phosphoric ester hydrolase activity F 0 1 1 0 100 4 22 2 18.18182 1100 -0.678 0.642 1 0005887 integral component of plasma membrane C 4 21 21 19.04762 100 4 21 21 19.04762 100 -0.57 0.648 1 0010557 positive regulation of macromolecule biosynthetic process P 0 0 0 0 0 2 6 1 33.33333 600 0.512 0.649 1 0010604 positive regulation of macromolecule metabolic process P 0 0 0 0 0 2 6 1 33.33333 600 0.512 0.649 1 0009893 positive regulation of metabolic process P 0 0 0 0 0 2 6 1 33.33333 600 0.512 0.649 1 0048518 positive regulation of biological process P 0 0 0 0 0 2 6 1 33.33333 600 0.512 0.649 1 0031328 positive regulation of cellular biosynthetic process P 0 0 0 0 0 2 6 1 33.33333 600 0.512 0.649 1 0031325 positive regulation of cellular metabolic process P 0 0 0 0 0 2 6 1 33.33333 600 0.512 0.649 1 0051173 positive regulation of nitrogen compound metabolic process P 0 0 0 0 0 2 6 1 33.33333 600 0.512 0.649 1 0009891 positive regulation of biosynthetic process P 0 0 0 0 0 2 6 1 33.33333 600 0.512 0.649 1 0010628 positive regulation of gene expression P 0 0 0 0 0 2 6 1 33.33333 600 0.512 0.649 1 0048522 positive regulation of cellular process P 0 0 0 0 0 2 6 1 33.33333 600 0.512 0.649 1 0051539 4 iron, 4 sulfur cluster binding F 8 28 28 28.57143 100 8 28 28 28.57143 100 0.521 0.65 1 0016868 intramolecular transferase activity, phosphotransferases F 1 4 4 25 100 2 6 5 33.33333 120 0.512 0.65 1 0051716 cellular response to stimulus P 0 0 0 0 0 22 99 37 22.22222 267.5676 -0.506 0.65 1 0006865 amino acid transport P 3 18 18 16.66667 100 6 30 19 20 157.8947 -0.56 0.653 1 0005506 iron ion binding F 8 47 47 17.02128 100 11 52 51 21.15385 101.9608 -0.545 0.656 1 0042401 cellular biogenic amine biosynthetic process P 0 0 0 0 0 2 6 6 33.33333 100 0.512 0.664 1 0009309 amine biosynthetic process P 0 0 0 0 0 2 6 6 33.33333 100 0.512 0.664 1 0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor F 0 2 2 0 100 1 7 4 14.28571 175 -0.622 0.672 1 0004601 peroxidase activity F 2 6 6 33.33333 100 2 6 6 33.33333 100 0.512 0.673 1 0003984 acetolactate synthase activity F 3 9 9 33.33333 100 3 9 9 33.33333 100 0.628 0.675 1 0046483 heterocycle metabolic process P 0 0 0 0 0 153 645 282 23.72093 228.7234 -0.438 0.675 1 0006575 cellular modified amino acid metabolic process P 0 0 0 0 0 7 34 6 20.58824 566.6667 -0.516 0.675 1 0009059 macromolecule biosynthetic process P 0 2 2 0 100 102 435 277 23.44828 157.0397 -0.487 0.677 1 0008408 3’-5’ exonuclease activity F 1 5 5 20 100 1 7 6 14.28571 116.6667 -0.622 0.68 1 0090150 establishment of protein localization to membrane P 0 0 0 0 0 1 7 5 14.28571 140 -0.622 0.68 1 0072657 protein localization to membrane P 0 0 0 0 0 1 7 5 14.28571 140 -0.622 0.68 1 1902580 single-organism cellular localization P 0 0 0 0 0 1 7 5 14.28571 140 -0.622 0.68 1 0009097 isoleucine biosynthetic process P 1 8 8 12.5 100 1 8 8 12.5 100 -0.783 0.68 1 0006549 isoleucine metabolic process P 0 0 0 0 0 1 8 8 12.5 100 -0.783 0.68 1 0016859 cis-trans isomerase activity F 0 0 0 0 0 1 7 6 14.28571 116.6667 -0.622 0.682 1 0003746 translation elongation factor activity F 1 8 8 12.5 100 1 8 8 12.5 100 -0.783 0.682 1 0004497 monooxygenase activity F 0 5 5 0 100 1 7 6 14.28571 116.6667 -0.622 0.685 1 0009147 pyrimidine nucleoside triphosphate metabolic process P 0 0 0 0 0 1 7 2 14.28571 350 -0.622 0.687 1 0044205 ’de novo’ UMP biosynthetic process P 1 7 7 14.28571 100 1 7 7 14.28571 100 -0.622 0.687 1 0033875 ribonucleoside bisphosphate metabolic process P 0 0 0 0 0 1 8 6 12.5 133.3333 -0.783 0.689 1 0033865 nucleoside bisphosphate metabolic process P 0 0 0 0 0 1 8 6 12.5 133.3333 -0.783 0.689 1 0034032 purine nucleoside bisphosphate metabolic process P 0 0 0 0 0 1 8 6 12.5 133.3333 -0.783 0.689 1 0006006 glucose metabolic process P 0 1 1 0 100 1 8 8 12.5 100 -0.783 0.689 1 0019318 hexose metabolic process P 0 0 0 0 0 1 8 8 12.5 100 -0.783 0.689 1 0016846 carbon-sulfur lyase activity F 0 4 4 0 100 1 7 6 14.28571 116.6667 -0.622 0.692 1 0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer F 0 6 6 0 100 1 7 7 14.28571 100 -0.622 0.692 1 0003774 motor activity F 1 8 8 12.5 100 1 8 8 12.5 100 -0.783 0.692 1 0004553 hydrolase activity, hydrolyzing O-glycosyl compounds F 1 7 7 14.28571 100 1 8 8 12.5 100 -0.783 0.692 1 0016877 ligase activity, forming carbon-sulfur bonds F 0 0 0 0 0 3 9 1 33.33333 900 0.628 0.693 1 0019319 hexose biosynthetic process P 0 0 0 0 0 1 7 7 14.28571 100 -0.622 0.693 1 0006094 gluconeogenesis P 1 7 7 14.28571 100 1 7 7 14.28571 100 -0.622 0.693 1 0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism F 0 0 0 0 0 1 8 4 12.5 200 -0.783 0.693 1 0034622 cellular macromolecular complex assembly P 0 0 0 0 0 1 7 3 14.28571 233.3333 -0.622 0.694 1 0005275 amine transmembrane transporter activity F 0 0 0 0 0 3 9 9 33.33333 100 0.628 0.695 1 0015424 amino acid-transporting ATPase activity F 3 9 9 33.33333 100 3 9 9 33.33333 100 0.628 0.695 1 0031263 amine-transporting ATPase activity F 0 0 0 0 0 3 9 9 33.33333 100 0.628 0.695 1 0003676 nucleic acid binding F 6 51 91 11.76471 56.04396 110 467 429 23.5546 108.8578 -0.449 0.695 1 0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor F 0 0 0 0 0 1 8 2 12.5 400 -0.783 0.696 1 0008170 N-methyltransferase activity F 0 1 1 0 100 1 7 2 14.28571 350 -0.622 0.698 1 0009070 serine family amino acid biosynthetic process P 0 0 0 0 0 1 7 2 14.28571 350 -0.622 0.7 1 0015036 disulfide oxidoreductase activity F 0 0 0 0 0 3 9 8 33.33333 112.5 0.628 0.704 1 0009225 nucleotide-sugar metabolic process P 1 1 1 100 100 1 8 3 12.5 266.6667 -0.783 0.706 1 0006753 nucleoside phosphate metabolic process P 0 0 0 0 0 21 93 23 22.58064 404.3478 -0.408 0.709 1 0046049 UMP metabolic process P 0 0 0 0 0 1 8 7 12.5 114.2857 -0.783 0.709 1 0006222 UMP biosynthetic process P 0 1 1 0 100 1 8 7 12.5 114.2857 -0.783 0.709 1 0009173 pyrimidine ribonucleoside monophosphate metabolic process P 0 0 0 0 0 1 8 7 12.5 114.2857 -0.783 0.709 1 0009174 pyrimidine ribonucleoside monophosphate biosynthetic process P 0 0 0 0 0 1 8 7 12.5 114.2857 -0.783 0.709 1 0006206 pyrimidine nucleobase metabolic process P 0 0 0 0 0 1 7 6 14.28571 116.6667 -0.622 0.712 1 0019856 pyrimidine nucleobase biosynthetic process P 1 1 1 100 100 1 7 6 14.28571 116.6667 -0.622 0.712 1 0007059 chromosome segregation P 1 8 8 12.5 100 1 8 8 12.5 100 -0.783 0.713 1 0009228 thiamine biosynthetic process P 3 9 9 33.33333 100 3 9 9 33.33333 100 0.628 0.715 1 0042723 thiamine-containing compound metabolic process P 0 0 0 0 0 3 9 9 33.33333 100 0.628 0.715 1 0006772 thiamine metabolic process P 0 0 0 0 0 3 9 9 33.33333 100 0.628 0.715 1 0042724 thiamine-containing compound biosynthetic process P 0 0 0 0 0 3 9 9 33.33333 100 0.628 0.715 1 0003333 amino acid transmembrane transport P 3 9 9 33.33333 100 3 10 10 30 100 0.416 0.715 1 1903825 organic acid transmembrane transport P 0 0 0 0 0 3 10 10 30 100 0.416 0.715 1 0043163 cell envelope organization P 0 0 0 0 0 1 8 8 12.5 100 -0.783 0.716 1 0044091 membrane biogenesis P 0 0 0 0 0 1 8 8 12.5 100 -0.783 0.716 1 0071709 membrane assembly P 0 0 0 0 0 1 8 8 12.5 100 -0.783 0.716 1 0043165 Gram-negative-bacterium-type cell outer membrane assembly P 1 8 8 12.5 100 1 8 8 12.5 100 -0.783 0.716 1 0000105 histidine biosynthetic process P 4 13 13 30.76923 100 4 13 13 30.76923 100 0.539 0.724 1 0006547 histidine metabolic process P 0 0 0 0 0 4 13 13 30.76923 100 0.539 0.724 1 0052803 imidazole-containing compound metabolic process P 0 0 0 0 0 4 13 13 30.76923 100 0.539 0.724 1 0004222 metalloendopeptidase activity F 3 10 10 30 100 3 10 10 30 100 0.416 0.724 1 0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds F 5 13 13 38.46154 100 13 49 17 26.53061 288.2353 0.357 0.724 1 0046031 ADP metabolic process P 0 0 0 0 0 2 12 12 16.66667 100 -0.622 0.731 1 0006096 glycolytic process P 2 12 12 16.66667 100 2 12 12 16.66667 100 -0.622 0.731 1 0006757 ATP generation from ADP P 0 0 0 0 0 2 12 12 16.66667 100 -0.622 0.731 1 0016491 oxidoreductase activity F 73 308 309 23.7013 99.67638 83 351 309 23.64672 113.5922 -0.336 0.732 1 0044265 cellular macromolecule catabolic process P 0 0 0 0 0 3 10 4 30 250 0.416 0.736 1 0009129 pyrimidine nucleoside monophosphate metabolic process P 0 0 0 0 0 2 11 7 18.18182 157.1429 -0.479 0.738 1 0009130 pyrimidine nucleoside monophosphate biosynthetic process P 0 0 0 0 0 2 11 7 18.18182 157.1429 -0.479 0.738 1 0008236 serine-type peptidase activity F 2 5 5 40 100 4 13 10 30.76923 130 0.539 0.745 1 0000988 transcription factor activity, protein binding F 0 0 0 0 0 4 13 12 30.76923 108.3333 0.539 0.745 1 0017171 serine hydrolase activity F 0 0 0 0 0 4 13 10 30.76923 130 0.539 0.745 1 0006188 IMP biosynthetic process P 0 1 1 0 100 2 12 12 16.66667 100 -0.622 0.754 1 0046040 IMP metabolic process P 0 0 0 0 0 2 12 12 16.66667 100 -0.622 0.754 1 0006189 ’de novo’ IMP biosynthetic process P 2 12 12 16.66667 100 2 12 12 16.66667 100 -0.622 0.754 1 0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances F 1 8 8 12.5 100 9 43 23 20.93023 186.9565 -0.529 0.755 1 0003995 acyl-CoA dehydrogenase activity F 4 14 14 28.57143 100 4 14 14 28.57143 100 0.368 0.756 1 0034645 cellular macromolecule biosynthetic process P 0 0 0 0 0 102 429 275 23.77622 156 -0.31 0.757 1 0006261 DNA-dependent DNA replication P 1 4 4 25 100 2 11 8 18.18182 137.5 -0.479 0.757 1 0015103 inorganic anion transmembrane transporter activity F 0 1 1 0 100 4 14 5 28.57143 280 0.368 0.759 1 0015291 secondary active transmembrane transporter activity F 0 0 0 0 0 3 15 1 20 1500 -0.395 0.759 1 0008080 N-acetyltransferase activity F 3 12 12 25 100 4 14 13 28.57143 107.6923 0.368 0.76 1 0051179 localization P 0 0 0 0 0 108 455 288 23.73626 157.9861 -0.343 0.76 1 0044781 bacterial-type flagellum organization P 2 9 9 22.22222 100 3 16 16 18.75 100 -0.525 0.762 1 0010181 FMN binding F 5 17 17 29.41176 100 5 17 17 29.41176 100 0.486 0.767 1 0016853 isomerase activity F 16 61 61 26.22951 100 17 65 61 26.15385 106.5574 0.34 0.77 1 0009063 cellular amino acid catabolic process P 0 0 0 0 0 4 14 4 28.57143 350 0.368 0.773 1 0016407 acetyltransferase activity F 0 1 1 0 100 5 18 2 27.77778 900 0.338 0.781 1 0006101 citrate metabolic process P 0 0 0 0 0 3 15 15 20 100 -0.395 0.781 1 0072350 tricarboxylic acid metabolic process P 0 0 0 0 0 3 15 15 20 100 -0.395 0.781 1 0006099 tricarboxylic acid cycle P 3 15 15 20 100 3 15 15 20 100 -0.395 0.781 1 0008514 organic anion transmembrane transporter activity F 0 0 0 0 0 3 15 1 20 1500 -0.395 0.786 1 0055114 oxidation-reduction process P 87 358 359 24.30168 99.72145 89 374 359 23.79679 104.1783 -0.276 0.787 1 1901293 nucleoside phosphate biosynthetic process P 0 0 0 0 0 14 62 23 22.58064 269.5652 -0.331 0.787 1 0009165 nucleotide biosynthetic process P 2 5 5 40 100 14 62 23 22.58064 269.5652 -0.331 0.787 1 0043933 macromolecular complex subunit organization P 0 0 0 0 0 5 18 4 27.77778 450 0.338 0.79 1 0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor F 3 13 13 23.07692 100 4 20 14 20 142.8571 -0.456 0.791 1 0051213 dioxygenase activity F 5 13 13 38.46154 100 6 21 13 28.57143 161.5385 0.451 0.801 1 0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor F 4 18 18 22.22222 100 6 22 18 27.27273 122.2222 0.319 0.801 1 0006400 tRNA modification P 2 7 7 28.57143 100 4 19 9 21.05263 211.1111 -0.337 0.803 1 0016769 transferase activity, transferring nitrogenous groups F 0 1 1 0 100 8 30 30 26.66667 100 0.295 0.804 1 0042625 ATPase activity, coupled to transmembrane movement of ions F 0 0 0 0 0 4 19 6 21.05263 316.6667 -0.337 0.806 1 0015698 inorganic anion transport P 0 1 1 0 100 4 20 6 20 333.3333 -0.456 0.809 1 0006631 fatty acid metabolic process P 2 9 9 22.22222 100 6 22 9 27.27273 244.4444 0.319 0.813 1 0008483 transaminase activity F 8 29 29 27.58621 100 8 29 29 27.58621 100 0.406 0.82 1 0008652 cellular amino acid biosynthetic process P 17 68 69 25 98.55073 22 96 69 22.91667 139.1304 -0.337 0.831 1 0006260 DNA replication P 6 25 25 24 100 6 28 27 21.42857 103.7037 -0.364 0.833 1 0035556 intracellular signal transduction P 0 0 0 0 0 10 45 45 22.22222 100 -0.338 0.838 1 0000160 phosphorelay signal transduction system P 10 45 45 22.22222 100 10 45 45 22.22222 100 -0.338 0.838 1 0009279 cell outer membrane C 8 35 35 22.85714 100 8 35 35 22.85714 100 -0.209 0.847 1 0016830 carbon-carbon lyase activity F 0 0 0 0 0 9 34 3 26.47059 1133.333 0.288 0.852 1 0019867 outer membrane C 9 27 27 33.33333 100 12 52 52 23.07692 100 -0.218 0.856 1 0098796 membrane protein complex C 0 0 0 0 0 12 52 2 23.07692 2600 -0.218 0.86 1 0009055 electron carrier activity F 13 46 46 28.26087 100 13 50 50 26 100 0.272 0.87 1 1902494 catalytic complex C 0 0 0 0 0 16 62 2 25.80645 3100 0.268 0.872 1 0006732 coenzyme metabolic process P 0 0 0 0 0 20 86 6 23.25581 1433.333 -0.243 0.881 1 0008150 biological_process P 0 0 0 0 0 546 2246 648 24.30989 346.6049 -0.156 0.894 1 0006810 transport P 70 273 273 25.64103 100 104 431 288 24.12993 149.6528 -0.124 0.895 1 0043234 protein complex C 0 0 0 0 0 22 87 1 25.28736 8700 0.204 0.901 1 0006139 nucleobase-containing compound metabolic process P 1 6 6 16.66667 100 133 552 282 24.0942 195.7447 -0.166 0.909 1 0006725 cellular aromatic compound metabolic process P 1 8 8 12.5 100 156 646 290 24.14861 222.7586 -0.147 0.911 1 0051234 establishment of localization P 0 0 0 0 0 105 435 288 24.13793 151.0417 -0.12 0.949 1 0052646 alditol phosphate metabolic process P 0 0 0 0 0 1 3 3 33.33333 100 0.362 1 1 0006072 glycerol-3-phosphate metabolic process P 1 3 3 33.33333 100 1 3 3 33.33333 100 0.362 1 1 0046037 GMP metabolic process P 1 1 1 100 100 1 3 3 33.33333 100 0.362 1 1 0051187 cofactor catabolic process P 0 0 0 0 0 1 3 2 33.33333 150 0.362 1 1 0008134 transcription factor binding F 1 3 3 33.33333 100 1 3 3 33.33333 100 0.362 1 1 0032784 regulation of DNA-templated transcription, elongation P 1 3 3 33.33333 100 1 3 3 33.33333 100 0.362 1 1 0005216 ion channel activity F 0 2 2 0 100 1 3 2 33.33333 150 0.362 1 1 0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor F 0 0 0 0 0 1 3 3 33.33333 100 0.362 1 1 0009109 coenzyme catabolic process P 0 0 0 0 0 1 3 2 33.33333 150 0.362 1 1 0003861 3-isopropylmalate dehydratase activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 0.362 1 1 1903530 regulation of secretion by cell P 0 0 0 0 0 1 3 3 33.33333 100 0.362 1 1 0004190 aspartic-type endopeptidase activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 0.362 1 1 0042803 protein homodimerization activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 0.362 1 1 0051223 regulation of protein transport P 0 0 0 0 0 1 3 3 33.33333 100 0.362 1 1 0015748 organophosphate ester transport P 0 0 0 0 0 1 3 1 33.33333 300 0.362 1 1 0046654 tetrahydrofolate biosynthetic process P 1 3 3 33.33333 100 1 3 3 33.33333 100 0.362 1 1 0004185 serine-type carboxypeptidase activity F 1 1 1 100 100 1 3 3 33.33333 100 0.362 1 1 0005381 iron ion transmembrane transporter activity F 0 1 1 0 100 1 3 3 33.33333 100 0.362 1 1 0001121 transcription from bacterial-type RNA polymerase promoter P 0 0 0 0 0 1 3 3 33.33333 100 0.362 1 1 0004529 exodeoxyribonuclease activity F 0 0 0 0 0 1 3 2 33.33333 150 0.362 1 1 0004784 superoxide dismutase activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 0.362 1 1 0016895 exodeoxyribonuclease activity, producing 5’-phosphomonoesters F 0 0 0 0 0 1 3 2 33.33333 150 0.362 1 1 0004803 transposase activity F 1 3 11 33.33333 27.27273 1 3 11 33.33333 27.27273 0.362 1 1 0015298 solute:cation antiporter activity F 0 0 0 0 0 1 3 3 33.33333 100 0.362 1 1 0070001 aspartic-type peptidase activity F 0 0 0 0 0 1 3 3 33.33333 100 0.362 1 1 0009424 bacterial-type flagellum hook C 1 3 3 33.33333 100 1 3 3 33.33333 100 0.362 1 1 0042802 identical protein binding F 0 0 0 0 0 1 3 3 33.33333 100 0.362 1 1 0006354 DNA-templated transcription, elongation P 0 1 1 0 100 1 3 3 33.33333 100 0.362 1 1 0019748 secondary metabolic process P 0 0 0 0 0 1 3 2 33.33333 150 0.362 1 1 0003905 alkylbase DNA N-glycosylase activity F 0 2 2 0 100 1 3 3 33.33333 100 0.362 1 1 0044209 AMP salvage P 1 3 3 33.33333 100 1 3 3 33.33333 100 0.362 1 1 0006166 purine ribonucleoside salvage P 0 1 1 0 100 1 3 3 33.33333 100 0.362 1 1 0001123 transcription initiation from bacterial-type RNA polymerase promoter P 1 3 3 33.33333 100 1 3 3 33.33333 100 0.362 1 1 0051046 regulation of secretion P 0 0 0 0 0 1 3 3 33.33333 100 0.362 1 1 0017004 cytochrome complex assembly P 1 3 3 33.33333 100 1 3 3 33.33333 100 0.362 1 1 0070201 regulation of establishment of protein localization P 0 0 0 0 0 1 3 3 33.33333 100 0.362 1 1 0006558 L-phenylalanine metabolic process P 0 0 0 0 0 1 3 1 33.33333 300 0.362 1 1 1902221 erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process P 0 0 0 0 0 1 3 1 33.33333 300 0.362 1 1 0050708 regulation of protein secretion P 0 2 2 0 100 1 3 3 33.33333 100 0.362 1 1 0060341 regulation of cellular localization P 0 0 0 0 0 1 3 3 33.33333 100 0.362 1 1 0030091 protein repair P 1 3 3 33.33333 100 1 3 3 33.33333 100 0.362 1 1 0032880 regulation of protein localization P 0 0 0 0 0 1 3 3 33.33333 100 0.362 1 1 0046471 phosphatidylglycerol metabolic process P 0 0 0 0 0 1 3 3 33.33333 100 0.362 1 1 0015299 solute:proton antiporter activity F 1 2 2 50 100 1 3 3 33.33333 100 0.362 1 1 0004733 pyridoxamine-phosphate oxidase activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 0.362 1 1 0016778 diphosphotransferase activity F 0 0 0 0 0 1 3 1 33.33333 300 0.362 1 1 0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor F 1 2 2 50 100 1 3 2 33.33333 150 0.362 1 1 0016882 cyclo-ligase activity F 0 0 0 0 0 1 3 1 33.33333 300 0.362 1 1 0070008 serine-type exopeptidase activity F 0 0 0 0 0 1 3 3 33.33333 100 0.362 1 1 0018065 protein-cofactor linkage P 0 0 0 0 0 1 3 2 33.33333 150 0.362 1 1 0046439 L-cysteine metabolic process P 1 3 3 33.33333 100 1 3 3 33.33333 100 0.362 1 1 0017172 cysteine dioxygenase activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 0.362 1 1 0043101 purine-containing compound salvage P 0 0 0 0 0 1 3 3 33.33333 100 0.362 1 1 0004075 biotin carboxylase activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 0.362 1 1 0016743 carboxyl- or carbamoyltransferase activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 0.362 1 1 0051052 regulation of DNA metabolic process P 0 0 0 0 0 1 3 2 33.33333 150 0.362 1 1 0022838 substrate-specific channel activity F 0 0 0 0 0 1 3 2 33.33333 150 0.362 1 1 0016721 oxidoreductase activity, acting on superoxide radicals as acceptor F 0 0 0 0 0 1 3 3 33.33333 100 0.362 1 1 0009157 deoxyribonucleoside monophosphate biosynthetic process P 0 0 0 0 0 1 3 1 33.33333 300 0.362 1 1 0009176 pyrimidine deoxyribonucleoside monophosphate metabolic process P 0 0 0 0 0 1 3 1 33.33333 300 0.362 1 1 0006655 phosphatidylglycerol biosynthetic process P 0 1 1 0 100 1 3 3 33.33333 100 0.362 1 1 0009162 deoxyribonucleoside monophosphate metabolic process P 0 0 0 0 0 1 3 1 33.33333 300 0.362 1 1 0009202 deoxyribonucleoside triphosphate biosynthetic process P 0 0 0 0 0 1 3 2 33.33333 150 0.362 1 1 0009177 pyrimidine deoxyribonucleoside monophosphate biosynthetic process P 0 0 0 0 0 1 3 1 33.33333 300 0.362 1 1 0032261 purine nucleotide salvage P 0 0 0 0 0 1 3 3 33.33333 100 0.362 1 1 0015412 molybdate transmembrane-transporting ATPase activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 0.362 1 1 0009212 pyrimidine deoxyribonucleoside triphosphate biosynthetic process P 0 0 0 0 0 1 3 2 33.33333 150 0.362 1 1 0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen F 0 2 2 0 100 1 3 3 33.33333 100 0.362 1 1 0030151 molybdenum ion binding F 2 7 7 28.57143 100 2 7 7 28.57143 100 0.26 1 1 0019104 DNA N-glycosylase activity F 0 3 3 0 100 2 7 4 28.57143 175 0.26 1 1 1901068 guanosine-containing compound metabolic process P 0 0 0 0 0 2 7 2 28.57143 350 0.26 1 1 0022803 passive transmembrane transporter activity F 0 0 0 0 0 2 7 5 28.57143 140 0.26 1 1 1990204 oxidoreductase complex C 0 0 0 0 0 2 7 2 28.57143 350 0.26 1 1 0004252 serine-type endopeptidase activity F 2 7 7 28.57143 100 2 7 7 28.57143 100 0.26 1 1 0006284 base-excision repair P 2 7 7 28.57143 100 2 7 7 28.57143 100 0.26 1 1 0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses F 0 0 0 0 0 2 7 1 28.57143 700 0.26 1 1 0046983 protein dimerization activity F 1 4 4 25 100 2 7 7 28.57143 100 0.26 1 1 0006739 NADP metabolic process P 0 0 0 0 0 2 7 2 28.57143 350 0.26 1 1 0015267 channel activity F 0 1 1 0 100 2 7 5 28.57143 140 0.26 1 1 0010605 negative regulation of macromolecule metabolic process P 0 0 0 0 0 2 7 3 28.57143 233.3333 0.26 1 1 0016742 hydroxymethyl-, formyl- and related transferase activity F 2 4 4 50 100 2 7 4 28.57143 175 0.26 1 1 0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor F 0 3 3 0 100 2 7 4 28.57143 175 0.26 1 1 0015074 DNA integration P 2 7 47 28.57143 14.89362 2 7 47 28.57143 14.89362 0.26 1 1 0016854 racemase and epimerase activity F 0 0 0 0 0 3 11 3 27.27273 366.6667 0.225 1 1 0015891 siderophore transport P 3 10 10 30 100 3 11 11 27.27273 100 0.225 1 1 0034655 nucleobase-containing compound catabolic process P 0 0 0 0 0 3 11 4 27.27273 275 0.225 1 1 0015688 iron chelate transport P 0 0 0 0 0 3 11 11 27.27273 100 0.225 1 1 0009073 aromatic amino acid family biosynthetic process P 4 11 12 36.36364 91.66666 4 15 13 26.66667 115.3846 0.208 1 1 0042180 cellular ketone metabolic process P 0 0 0 0 0 4 15 1 26.66667 1500 0.208 1 1 0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups F 0 4 4 0 100 5 19 4 26.31579 475 0.199 1 1 0009064 glutamine family amino acid metabolic process P 0 0 0 0 0 8 32 9 25 355.5555 0.084 1 1 0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides F 0 3 3 0 100 6 24 5 25 480 0.073 1 1 0016798 hydrolase activity, acting on glycosyl bonds F 3 14 14 21.42857 100 5 20 15 25 133.3333 0.066 1 1 0050662 coenzyme binding F 1 8 8 12.5 100 30 122 21 24.59016 580.9524 0.059 1 1 0071702 organic substance transport P 0 0 0 0 0 30 122 43 24.59016 283.7209 0.059 1 1 0009132 nucleoside diphosphate metabolic process P 0 0 0 0 0 4 16 13 25 123.0769 0.059 1 1 0071806 protein transmembrane transport P 0 2 2 0 100 4 16 3 25 533.3333 0.059 1 1 1901678 iron coordination entity transport P 0 0 0 0 0 3 12 11 25 109.0909 0.051 1 1 0016744 transferase activity, transferring aldehyde or ketonic groups F 0 0 0 0 0 3 12 9 25 133.3333 0.051 1 1 0030246 carbohydrate binding F 2 7 7 28.57143 100 2 8 8 25 100 0.042 1 1 0016780 phosphotransferase activity, for other substituted phosphate groups F 1 4 4 25 100 2 8 6 25 133.3333 0.042 1 1 0009089 lysine biosynthetic process via diaminopimelate P 2 8 8 25 100 2 8 8 25 100 0.042 1 1 0009085 lysine biosynthetic process P 2 7 7 28.57143 100 2 8 8 25 100 0.042 1 1 0046451 diaminopimelate metabolic process P 0 0 0 0 0 2 8 8 25 100 0.042 1 1 0030234 enzyme regulator activity F 0 2 2 0 100 1 4 3 25 133.3333 0.03 1 1 0043174 nucleoside salvage P 0 0 0 0 0 1 4 3 25 133.3333 0.03 1 1 0003840 gamma-glutamyltransferase activity F 1 4 4 25 100 1 4 4 25 100 0.03 1 1 0016790 thiolester hydrolase activity F 1 2 2 50 100 1 4 3 25 133.3333 0.03 1 1 0046961 proton-transporting ATPase activity, rotational mechanism F 1 4 4 25 100 1 4 4 25 100 0.03 1 1 0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process P 0 0 0 0 0 1 4 2 25 200 0.03 1 1 0006534 cysteine metabolic process P 0 0 0 0 0 1 4 3 25 133.3333 0.03 1 1 0009200 deoxyribonucleoside triphosphate metabolic process P 0 0 0 0 0 1 4 2 25 200 0.03 1 1 0008175 tRNA methyltransferase activity F 0 1 1 0 100 1 4 2 25 200 0.03 1 1 0004457 lactate dehydrogenase activity F 0 1 1 0 100 1 4 1 25 400 0.03 1 1 0015940 pantothenate biosynthetic process P 1 4 4 25 100 1 4 4 25 100 0.03 1 1 0015098 molybdate ion transmembrane transporter activity F 0 2 2 0 100 1 4 4 25 100 0.03 1 1 0008374 O-acyltransferase activity F 0 0 0 0 0 1 4 1 25 400 0.03 1 1 0098772 molecular function regulator F 0 0 0 0 0 1 4 3 25 133.3333 0.03 1 1 0043623 cellular protein complex assembly P 0 0 0 0 0 1 4 3 25 133.3333 0.03 1 1 0036442 hydrogen-exporting ATPase activity F 0 0 0 0 0 1 4 4 25 100 0.03 1 1 0070475 rRNA base methylation P 1 3 3 33.33333 100 1 4 4 25 100 0.03 1 1 0009265 2’-deoxyribonucleotide biosynthetic process P 0 0 0 0 0 1 4 1 25 400 0.03 1 1 0003690 double-stranded DNA binding F 0 1 1 0 100 1 4 2 25 200 0.03 1 1 0015288 porin activity F 1 4 4 25 100 1 4 4 25 100 0.03 1 1 0009221 pyrimidine deoxyribonucleotide biosynthetic process P 0 0 0 0 0 1 4 1 25 400 0.03 1 1 0043173 nucleotide salvage P 0 0 0 0 0 1 4 3 25 133.3333 0.03 1 1 0015297 antiporter activity F 0 1 1 0 100 1 4 4 25 100 0.03 1 1 0009263 deoxyribonucleotide biosynthetic process P 0 0 0 0 0 1 4 1 25 400 0.03 1 1 0009219 pyrimidine deoxyribonucleotide metabolic process P 0 0 0 0 0 1 4 1 25 400 0.03 1 1 0009394 2’-deoxyribonucleotide metabolic process P 0 0 0 0 0 1 4 1 25 400 0.03 1 1 0046385 deoxyribose phosphate biosynthetic process P 0 0 0 0 0 1 4 1 25 400 0.03 1 1 0019692 deoxyribose phosphate metabolic process P 0 0 0 0 0 1 4 1 25 400 0.03 1 1 0008289 lipid binding F 1 3 3 33.33333 100 1 4 4 25 100 0.03 1 1 0051049 regulation of transport P 0 0 0 0 0 1 4 3 25 133.3333 0.03 1 1 0009448 gamma-aminobutyric acid metabolic process P 1 2 2 50 100 1 4 4 25 100 0.03 1 1 0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines F 1 3 3 33.33333 100 1 4 3 25 133.3333 0.03 1 1 0022829 wide pore channel activity F 0 0 0 0 0 1 4 4 25 100 0.03 1 1 0003743 translation initiation factor activity F 1 4 4 25 100 1 4 4 25 100 0.03 1 1 0006826 iron ion transport P 1 3 3 33.33333 100 1 4 4 25 100 0.03 1 1 0016838 carbon-oxygen lyase activity, acting on phosphates F 0 1 1 0 100 1 4 1 25 400 0.03 1 1 0065008 regulation of biological quality P 0 0 0 0 0 13 53 4 24.5283 1325 0.028 1 1 1901360 organic cyclic compound metabolic process P 0 0 0 0 0 162 664 282 24.39759 235.461 0.023 1 1 0050660 flavin adenine dinucleotide binding F 10 42 42 23.80952 100 11 45 45 24.44444 100 0.013 1 1 GO Gene Ontology r 0 0 0 0 0 642 2635 2686 24.36433 98.10126 0 1 1 0051188 cofactor biosynthetic process P 0 1 1 0 100 19 78 7 24.35897 1114.286 -0.001 1 1 0032787 monocarboxylic acid metabolic process P 0 0 0 0 0 18 74 9 24.32432 822.2222 -0.008 1 1 0008509 anion transmembrane transporter activity F 0 0 0 0 0 7 29 1 24.13793 2900 -0.029 1 1 0071944 cell periphery C 0 0 0 0 0 96 396 99 24.24242 400 -0.061 1 1 0016866 intramolecular transferase activity F 0 2 2 0 100 4 17 6 23.52941 283.3333 -0.08 1 1 0016410 N-acyltransferase activity F 0 2 2 0 100 4 17 3 23.52941 566.6667 -0.08 1 1 0030030 cell projection organization P 0 0 0 0 0 4 17 1 23.52941 1700 -0.08 1 1 0045454 cell redox homeostasis P 4 17 17 23.52941 100 4 17 17 23.52941 100 -0.08 1 1 0044459 plasma membrane part C 0 0 0 0 0 15 63 22 23.80952 286.3636 -0.104 1 1 0009185 ribonucleoside diphosphate metabolic process P 0 0 0 0 0 3 13 12 23.07692 108.3333 -0.108 1 1 0015171 amino acid transmembrane transporter activity F 0 0 0 0 0 3 13 1 23.07692 1300 -0.108 1 1 0009179 purine ribonucleoside diphosphate metabolic process P 0 0 0 0 0 3 13 12 23.07692 108.3333 -0.108 1 1 0009135 purine nucleoside diphosphate metabolic process P 0 0 0 0 0 3 13 12 23.07692 108.3333 -0.108 1 1 0046434 organophosphate catabolic process P 0 0 0 0 0 2 9 1 22.22222 900 -0.15 1 1 0016840 carbon-nitrogen lyase activity F 0 1 1 0 100 2 9 2 22.22222 450 -0.15 1 1 0006553 lysine metabolic process P 0 0 0 0 0 2 9 8 22.22222 112.5 -0.15 1 1 0008237 metallopeptidase activity F 4 17 17 23.52941 100 5 22 20 22.72727 110 -0.18 1 1 0016831 carboxy-lyase activity F 2 9 9 22.22222 100 4 18 9 22.22222 200 -0.212 1 1 0006768 biotin metabolic process P 0 0 0 0 0 1 5 5 20 100 -0.228 1 1 0019201 nucleotide kinase activity F 0 0 0 0 0 1 5 1 20 500 -0.228 1 1 0003916 DNA topoisomerase activity F 1 5 5 20 100 1 5 5 20 100 -0.228 1 1 0045017 glycerolipid biosynthetic process P 0 0 0 0 0 1 5 3 20 166.6667 -0.228 1 1 0006544 glycine metabolic process P 0 2 2 0 100 1 5 3 20 166.6667 -0.228 1 1 0006167 AMP biosynthetic process P 0 0 0 0 0 1 5 3 20 166.6667 -0.228 1 1 0065009 regulation of molecular function P 0 0 0 0 0 1 5 1 20 500 -0.228 1 1 0046474 glycerophospholipid biosynthetic process P 0 0 0 0 0 1 5 3 20 166.6667 -0.228 1 1 0009098 leucine biosynthetic process P 1 5 5 20 100 1 5 5 20 100 -0.228 1 1 0016758 transferase activity, transferring hexosyl groups F 0 1 1 0 100 1 5 2 20 250 -0.228 1 1 0006265 DNA topological change P 1 5 5 20 100 1 5 5 20 100 -0.228 1 1 0043022 ribosome binding F 1 5 5 20 100 1 5 5 20 100 -0.228 1 1 0051205 protein insertion into membrane P 1 5 5 20 100 1 5 5 20 100 -0.228 1 1 0032879 regulation of localization P 0 0 0 0 0 1 5 3 20 166.6667 -0.228 1 1 0009102 biotin biosynthetic process P 1 5 5 20 100 1 5 5 20 100 -0.228 1 1 0046033 AMP metabolic process P 1 1 1 100 100 1 5 3 20 166.6667 -0.228 1 1 0015939 pantothenate metabolic process P 0 0 0 0 0 1 5 4 20 125 -0.228 1 1 0009099 valine biosynthetic process P 1 5 5 20 100 1 5 5 20 100 -0.228 1 1 0046219 indolalkylamine biosynthetic process P 0 0 0 0 0 1 5 6 20 83.33334 -0.228 1 1 0071949 FAD binding F 1 5 5 20 100 1 5 5 20 100 -0.228 1 1 0006749 glutathione metabolic process P 1 4 4 25 100 1 5 5 20 100 -0.228 1 1 0015689 molybdate ion transport P 1 5 5 20 100 1 5 5 20 100 -0.228 1 1 0004659 prenyltransferase activity F 1 4 4 25 100 1 5 4 20 125 -0.228 1 1 0042435 indole-containing compound biosynthetic process P 0 0 0 0 0 1 5 6 20 83.33334 -0.228 1 1 0051156 glucose 6-phosphate metabolic process P 1 1 1 100 100 1 5 5 20 100 -0.228 1 1 0002161 aminoacyl-tRNA editing activity F 1 5 5 20 100 1 5 5 20 100 -0.228 1 1 0019877 diaminopimelate biosynthetic process P 1 5 5 20 100 1 5 5 20 100 -0.228 1 1 0008169 C-methyltransferase activity F 0 0 0 0 0 1 5 1 20 500 -0.228 1 1 0030258 lipid modification P 0 0 0 0 0 1 5 1 20 500 -0.228 1 1 0044877 macromolecular complex binding F 0 0 0 0 0 1 5 5 20 100 -0.228 1 1 0043021 ribonucleoprotein complex binding F 0 0 0 0 0 1 5 5 20 100 -0.228 1 1 0008658 penicillin binding F 1 5 5 20 100 1 5 5 20 100 -0.228 1 1 0008144 drug binding F 0 0 0 0 0 1 5 5 20 100 -0.228 1 1 0004180 carboxypeptidase activity F 1 5 5 20 100 1 5 5 20 100 -0.228 1 1 0050790 regulation of catalytic activity P 1 3 3 33.33333 100 1 5 4 20 125 -0.228 1 1 0000162 tryptophan biosynthetic process P 1 5 6 20 83.33334 1 5 6 20 83.33334 -0.228 1 1 0046915 transition metal ion transmembrane transporter activity F 0 0 0 0 0 1 5 3 20 166.6667 -0.228 1 1 0006551 leucine metabolic process P 0 0 0 0 0 1 5 5 20 100 -0.228 1 1 0046943 carboxylic acid transmembrane transporter activity F 0 0 0 0 0 3 14 1 21.42857 1400 -0.257 1 1 0005342 organic acid transmembrane transporter activity F 0 0 0 0 0 3 14 1 21.42857 1400 -0.257 1 1 1901617 organic hydroxy compound biosynthetic process P 0 0 0 0 0 2 10 5 20 200 -0.322 1 1 0016776 phosphotransferase activity, phosphate group as acceptor F 0 2 2 0 100 2 10 2 20 500 -0.322 1 1 0071897 DNA biosynthetic process P 2 10 10 20 100 2 10 10 20 100 -0.322 1 1 0034061 DNA polymerase activity F 0 0 0 0 0 2 10 10 20 100 -0.322 1 1 0003887 DNA-directed DNA polymerase activity F 2 10 10 20 100 2 10 10 20 100 -0.322 1 1 0052689 carboxylic ester hydrolase activity F 0 1 1 0 100 2 10 6 20 166.6667 -0.322 1 1 0006450 regulation of translational fidelity P 1 6 6 16.66667 100 1 6 6 16.66667 100 -0.44 1 1 0033293 monocarboxylic acid binding F 0 0 0 0 0 1 6 5 16.66667 120 -0.44 1 1 0006448 regulation of translational elongation P 0 0 0 0 0 1 6 6 16.66667 100 -0.44 1 1 0019205 nucleobase-containing compound kinase activity F 0 1 1 0 100 1 6 1 16.66667 600 -0.44 1 1 0006289 nucleotide-excision repair P 1 5 5 20 100 1 6 6 16.66667 100 -0.44 1 1 0006573 valine metabolic process P 0 0 0 0 0 1 6 5 16.66667 120 -0.44 1 1 1901264 carbohydrate derivative transport P 0 0 0 0 0 1 6 3 16.66667 200 -0.44 1 1 0009982 pseudouridine synthase activity F 1 6 6 16.66667 100 1 6 6 16.66667 100 -0.44 1 1 0003684 damaged DNA binding F 1 6 6 16.66667 100 1 6 6 16.66667 100 -0.44 1 1 0033218 amide binding F 0 0 0 0 0 1 6 5 16.66667 120 -0.44 1 1 0016755 transferase activity, transferring amino-acyl groups F 0 0 0 0 0 1 6 1 16.66667 600 -0.44 1 1 0009148 pyrimidine nucleoside triphosphate biosynthetic process P 0 0 0 0 0 1 6 2 16.66667 300 -0.44 1 1 0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5’-phosphomonoesters F 0 0 0 0 0 1 6 2 16.66667 300 -0.44 1 1 0001522 pseudouridine synthesis P 1 6 6 16.66667 100 1 6 6 16.66667 100 -0.44 1 1 0000041 transition metal ion transport P 0 1 1 0 100 1 6 5 16.66667 120 -0.44 1 1 0008982 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0019344 cysteine biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004781 sulfate adenylyltransferase (ATP) activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0034219 carbohydrate transmembrane transport P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006535 cysteine biosynthetic process from serine P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008813 chorismate lyase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0019419 sulfate reduction P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006646 phosphatidylethanolamine biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008882 [glutamate-ammonia-ligase] adenylyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004124 cysteine synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008920 lipopolysaccharide heptosyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008761 UDP-N-acetylglucosamine 2-epimerase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0050560 aspartate-tRNA(Asn) ligase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0015430 glycerol-3-phosphate-transporting ATPase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004735 pyrroline-5-carboxylate reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0003985 acetyl-CoA C-acetyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004609 phosphatidylserine decarboxylase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0001530 lipopolysaccharide binding F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008312 7S RNA binding F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0048500 signal recognition particle C 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008807 carboxyvinyl-carboxyphosphonate phosphorylmutase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0019897 extrinsic component of plasma membrane C 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008794 arsenate reductase (glutaredoxin) activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0019143 3-deoxy-manno-octulosonate-8-phosphatase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0015221 lipopolysaccharide transmembrane transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004349 glutamate 5-kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0036439 glycerol-3-phosphate dehydrogenase [NADP+] activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008720 D-lactate dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004044 amidophosphoribosyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0046538 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0000967 rRNA 5’-end processing P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0009294 DNA mediated transformation P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0042286 glutamate-1-semialdehyde 2,1-aminomutase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004848 ureidoglycolate hydrolase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0047952 glycerol-3-phosphate dehydrogenase [NAD(P)+] activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0046168 glycerol-3-phosphate catabolic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0046167 glycerol-3-phosphate biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0045302 choloylglycine hydrolase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0070006 metalloaminopeptidase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0009431 bacterial-type flagellum basal body, MS ring C 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0001682 tRNA 5’-leader removal P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0070084 protein initiator methionine removal P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004526 ribonuclease P activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0033862 UMP kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0009041 uridylate kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004605 phosphatidate cytidylyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0016024 CDP-diacylglycerol biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0030604 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0070402 NADPH binding F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0019171 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008773 [protein-PII] uridylyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0046890 regulation of lipid biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008712 ADP-glyceromanno-heptose 6-epimerase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004712 protein serine/threonine/tyrosine kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0005992 trehalose biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0033942 4-alpha-D-{(1->4)-alpha-D-glucano}trehalose trehalohydrolase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004133 glycogen debranching enzyme activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0005980 glycogen catabolic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004414 homoserine O-acetyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0003844 1,4-alpha-glucan branching enzyme activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0005978 glycogen biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008883 glutamyl-tRNA reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004462 lactoylglutathione lyase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008995 ribonuclease E activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0044341 sodium-dependent phosphate transport P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006109 regulation of carbohydrate metabolic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0031235 intrinsic component of the cytoplasmic side of the plasma membrane C 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0018339 peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008677 2-dehydropantoate 2-reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0022820 potassium ion symporter activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0070476 rRNA (guanine-N7)-methylation P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0009427 bacterial-type flagellum basal body, distal rod, L ring C 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004053 arginase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0009428 bacterial-type flagellum basal body, distal rod, P ring C 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008874 gluconate 5-dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0070043 rRNA (guanine-N7-)-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0050385 ureidoglycolate lyase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004587 ornithine-oxo-acid transaminase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004156 dihydropteroate synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006107 oxaloacetate metabolic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008968 D-sedoheptulose 7-phosphate isomerase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008964 phosphoenolpyruvate carboxylase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0017001 antibiotic catabolic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0042301 phosphate ion binding F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008119 thiopurine S-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006799 polyphosphate biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008976 polyphosphate kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0009358 polyphosphate kinase complex C 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004309 exopolyphosphatase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0042132 fructose 1,6-bisphosphate 1-phosphatase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008685 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0000256 allantoin catabolic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008966 phosphoglucosamine mutase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008121 ubiquinol-cytochrome-c reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0000716 transcription-coupled nucleotide-excision repair, DNA damage recognition P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004375 glycine dehydrogenase (decarboxylating) activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0005960 glycine cleavage complex C 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0061542 3-demethylubiquinone-n 3-O-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004647 phosphoserine phosphatase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0050182 phosphate butyryltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004648 O-phospho-L-serine:2-oxoglutarate aminotransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008650 rRNA (uridine-2’-O-)-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004413 homoserine kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004047 aminomethyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004824 lysine-tRNA ligase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006430 lysyl-tRNA aminoacylation P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0050518 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0009307 DNA restriction-modification system P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0042883 cysteine transport P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004476 mannose-6-phosphate isomerase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004588 orotate phosphoribosyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0003999 adenine phosphoribosyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008984 protein-glutamate methylesterase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0050920 regulation of chemotaxis P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0052381 tRNA dimethylallyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0019295 coenzyme M biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008479 queuine tRNA-ribosyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006168 adenine salvage P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004845 uracil phosphoribosyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006223 uracil salvage P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0015977 carbon fixation P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0044206 UMP salvage P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0015415 phosphate ion transmembrane-transporting ATPase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004641 phosphoribosylformylglycinamidine cyclo-ligase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0032297 negative regulation of DNA-dependent DNA replication initiation P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004459 L-lactate dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0043631 RNA polyadenylation P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006378 mRNA polyadenylation P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004652 polynucleotide adenylyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0003848 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0003991 acetylglutamate kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008689 3-demethylubiquinone-9 3-O-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008694 3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0071945 regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0035438 cyclic-di-GMP binding F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0000453 enzyme-directed rRNA 2’-O-methylation P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008655 pyrimidine-containing compound salvage P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004742 dihydrolipoyllysine-residue acetyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008409 5’-3’ exonuclease activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006567 threonine catabolic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004654 polyribonucleotide nucleotidyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0016117 carotenoid biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0000175 3’-5’-exoribonuclease activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0003882 CDP-diacylglycerol-serine O-phosphatidyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004617 phosphoglycerate dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004455 ketol-acid reductoisomerase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0016767 geranylgeranyl-diphosphate geranylgeranyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0015501 glutamate:sodium symporter activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008977 prephenate dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006855 drug transmembrane transport P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004807 triose-phosphate isomerase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0003866 3-phosphoshikimate 1-carboxyvinyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0045254 pyruvate dehydrogenase complex C 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0015813 L-glutamate transport P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 1903830 magnesium ion transmembrane transport P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004127 cytidylate kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008831 dTDP-4-dehydrorhamnose reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008830 dTDP-4-dehydrorhamnose 3,5-epimerase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0089711 L-glutamate transmembrane transport P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0042866 pyruvate biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004077 biotin-[acetyl-CoA-carboxylase] ligase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0050992 dimethylallyl diphosphate biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0051745 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0051304 chromosome separation P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004594 pantothenate kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008806 carboxymethylenebutenolidase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0015238 drug transmembrane transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006827 high-affinity iron ion transmembrane transport P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0015321 sodium-dependent phosphate transmembrane transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0070677 rRNA (cytosine-2’-O-)-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008792 arginine decarboxylase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008776 acetate kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008829 dCTP deaminase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004149 dihydrolipoyllysine-residue succinyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0033512 L-lysine catabolic process to acetyl-CoA via saccharopine P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0045252 oxoglutarate dehydrogenase complex C 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006229 dUTP biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004830 tryptophan-tRNA ligase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006436 tryptophanyl-tRNA aminoacylation P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004618 phosphoglycerate kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0015772 oligosaccharide transport P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004825 methionine-tRNA ligase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 2001061 D-glycero-D-manno-heptose 7-phosphate biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0033573 high-affinity iron permease complex C 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0015204 urea transmembrane transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0071918 urea transmembrane transport P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006449 regulation of translational termination P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004069 L-aspartate:2-oxoglutarate aminotransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0015886 heme transport P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0009234 menaquinone biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004802 transketolase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0009420 bacterial-type flagellum filament C 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0015439 heme-transporting ATPase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0047421 N-acyl-D-glutamate deacylase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004665 prephenate dehydrogenase (NADP+) activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006571 tyrosine biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006431 methionyl-tRNA aminoacylation P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0019203 carbohydrate phosphatase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016418 S-acetyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016453 C-acetyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0008875 gluconate dehydrogenase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0000255 allantoin metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0018197 peptidyl-aspartic acid modification P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0009292 genetic transfer P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0070548 L-glutamine aminotransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0000715 nucleotide-excision repair, DNA damage recognition P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0003988 acetyl-CoA C-acyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0050308 sugar-phosphatase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 1902475 L-alpha-amino acid transmembrane transport P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0030551 cyclic nucleotide binding F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 1902021 regulation of bacterial-type flagellum-dependent cell motility P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 2000145 regulation of cell motility P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0051270 regulation of cellular component movement P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0019296 coenzyme M metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0044355 clearance of foreign intracellular DNA P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0006952 defense response P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0019216 regulation of lipid metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0030174 regulation of DNA-dependent DNA replication initiation P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0006283 transcription-coupled nucleotide-excision repair P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0000966 RNA 5’-end processing P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0044247 cellular polysaccharide catabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 2000104 negative regulation of DNA-dependent DNA replication P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0008156 negative regulation of DNA replication P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0051053 negative regulation of DNA metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0043096 purine nucleobase salvage P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0046084 adenine biosynthetic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0046083 adenine metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016681 oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016408 C-acyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0034471 ncRNA 5’-end processing P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0030523 dihydrolipoamide S-acyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0015232 heme transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 2001060 D-glycero-D-manno-heptose 7-phosphate metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0005313 L-glutamate transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0015172 acidic amino acid transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0015179 L-amino acid transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0005310 dicarboxylic acid transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0015800 acidic amino acid transport P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0015807 L-amino acid transport P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0006835 dicarboxylic acid transport P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016869 intramolecular transferase activity, transferring amino groups F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0015665 alcohol transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0004779 sulfate adenylyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016116 carotenoid metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0004337 geranyltranstransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0015893 drug transport P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0042493 response to drug P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0090484 drug transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0050993 dimethylallyl diphosphate metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0019898 extrinsic component of membrane C 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016109 tetraterpenoid biosynthetic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0015166 polyol transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0019755 one-carbon compound transport P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 1901618 organic hydroxy compound transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0015605 organophosphate ester transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0046337 phosphatidylethanolamine metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0030611 arsenate reductase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0030614 oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0030613 oxidoreductase activity, acting on phosphorus or arsenic in donors F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0046351 disaccharide biosynthetic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0005991 trehalose metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0008703 5-amino-6-(5-phosphoribosylamino)uracil reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0015169 glycerol-3-phosphate transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0006797 polyphosphate metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0051723 protein methylesterase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0032101 regulation of response to external stimulus P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0050795 regulation of behavior P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0007610 behavior P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0043100 pyrimidine nucleobase salvage P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0046107 uracil biosynthetic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0019860 uracil metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0010138 pyrimidine ribonucleotide salvage P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016108 tetraterpenoid metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0043097 pyrimidine nucleoside salvage P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0031124 mRNA 3’-end processing P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016751 S-succinyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0019474 L-lysine catabolic process to acetyl-CoA P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0019477 L-lysine catabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0006554 lysine catabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0046440 L-lysine metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0045240 dihydrolipoyl dehydrogenase complex C 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0034755 iron ion transmembrane transport P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0042887 amide transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0015840 urea transport P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0032262 pyrimidine nucleotide salvage P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004749 ribose phosphate diphosphokinase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008961 phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004844 uracil DNA N-glycosylase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0001680 tRNA 3’-terminal CCA addition P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004810 tRNA adenylyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0016437 tRNA cytidylyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0042245 RNA repair P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0052927 CTP:tRNA cytidylyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0003868 4-hydroxyphenylpyruvate dioxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0052929 ATP:3’-cytidine-cytidine-tRNA adenylyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0047480 UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004013 adenosylhomocysteinase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004478 methionine adenosyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006556 S-adenosylmethionine biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0015099 nickel cation transmembrane transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0035444 nickel cation transmembrane transport P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0042888 molybdenum ion transmembrane transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0043023 ribosomal large subunit binding F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004045 aminoacyl-tRNA hydrolase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0090329 regulation of DNA-dependent DNA replication P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0052928 CTP:3’-cytidine-tRNA cytidylyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0051258 protein polymerization P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008835 diaminohydroxyphosphoribosylaminopyrimidine deaminase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004372 glycine hydroxymethyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0019264 glycine biosynthetic process from serine P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0097175 1,6-anhydro-N-acetyl-beta-muramic acid catabolic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004818 glutamate-tRNA ligase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0003855 3-dehydroquinate dehydratase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004764 shikimate 3-dehydrogenase (NADP+) activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0019632 shikimate metabolic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008113 peptide-methionine (S)-S-oxide reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008759 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006015 5-phosphoribose 1-diphosphate biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008716 D-alanine-D-alanine ligase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008763 UDP-N-acetylmuramate-L-alanine ligase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0030259 lipid glycosylation P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0050511 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0051991 UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0015836 lipid-linked peptidoglycan transport P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0015648 lipid-linked peptidoglycan transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008764 UDP-N-acetylmuramoylalanine-D-glutamate ligase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008766 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0016416 O-palmitoyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008097 5S rRNA binding F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0000906 6,7-dimethyl-8-ribityllumazine synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0009349 riboflavin synthase complex C 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0009030 thiamine-phosphate kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008962 phosphatidylglycerophosphatase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0009395 phospholipid catabolic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004590 orotidine-5’-phosphate decarboxylase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004143 diacylglycerol kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0042925 benzoate transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0070039 rRNA (guanosine-2’-O-)-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0042919 benzoate transport P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0031418 L-ascorbic acid binding F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004055 argininosuccinate synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008785 alkyl hydroperoxide reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0018271 biotin-protein ligase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0009233 menaquinone metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016642 oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016999 antibiotic metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0017144 drug metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0004611 phosphoenolpyruvate carboxykinase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0008859 exoribonuclease II activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0015095 magnesium ion transmembrane transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0050515 4-(cytidine 5’-diphospho)-2-C-methyl-D-erythritol kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004066 asparagine synthase (glutamine-hydrolyzing) activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006529 asparagine biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004416 hydroxyacylglutathione hydrolase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008933 lytic transglycosylase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0000918 barrier septum site selection P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0032955 regulation of barrier septum assembly P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004595 pantetheine-phosphate adenylyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004048 anthranilate phosphoribosyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0009251 glucan catabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0004750 ribulose-phosphate 3-epimerase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004150 dihydroneopterin aldolase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004853 uroporphyrinogen decarboxylase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0018580 nitronate monooxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006878 cellular copper ion homeostasis P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006729 tetrahydrobiopterin biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004152 dihydroorotate dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004057 arginyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0016598 protein arginylation P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0047451 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0043628 ncRNA 3’-end processing P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0032954 regulation of cytokinetic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0008746 NAD(P)+ transhydrogenase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016652 oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0097174 1,6-anhydro-N-acetyl-beta-muramic acid metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016409 palmitoyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0070085 glycosylation P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0015835 peptidoglycan transport P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0015647 peptidoglycan transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0070838 divalent metal ion transport P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0042780 tRNA 3’-end processing P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0072509 divalent inorganic cation transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016802 trialkylsulfonium hydrolase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016801 hydrolase activity, acting on ether bonds F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0046500 S-adenosylmethionine metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0015675 nickel cation transport P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0046391 5-phosphoribose 1-diphosphate metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0006528 asparagine metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0061727 methylglyoxal catabolic process to lactate P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0051596 methylglyoxal catabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0010466 negative regulation of peptidase activity P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0097506 deaminated base DNA N-glycosylase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0008308 voltage-gated anion channel activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0005984 disaccharide metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0052548 regulation of endopeptidase activity P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0051346 negative regulation of hydrolase activity P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0043086 negative regulation of catalytic activity P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0044092 negative regulation of molecular function P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0019614 catechol-containing compound catabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0019336 phenol-containing compound catabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0005254 chloride channel activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0072511 divalent inorganic cation transport P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0005253 anion channel activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0032465 regulation of cytokinesis P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0005244 voltage-gated ion channel activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0022832 voltage-gated channel activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0034765 regulation of ion transmembrane transport P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0044070 regulation of anion transport P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0043269 regulation of ion transport P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0034762 regulation of transmembrane transport P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0033467 CMP-keto-3-deoxy-D-manno-octulosonic acid metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0051066 dihydrobiopterin metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0052863 1-deoxy-D-xylulose 5-phosphate metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0015108 chloride transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0042084 5-methyltetrahydrofolate-dependent methyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 1901891 regulation of cell septum assembly P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0006473 protein acetylation P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0043543 protein acylation P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0031365 N-terminal protein amino acid modification P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0000819 sister chromatid segregation P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0098813 nuclear chromosome segregation P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0003909 DNA ligase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016886 ligase activity, forming phosphoric ester bonds F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016867 intramolecular transferase activity, transferring acyl groups F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0051180 vitamin transport P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0042910 xenobiotic transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016793 triphosphoric monoester hydrolase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0004311 farnesyltranstransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0048033 heme o metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0046160 heme a metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0046292 formaldehyde metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0006067 ethanol metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0019276 UDP-N-acetylgalactosamine metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0019400 alditol metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0019405 alditol catabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0051183 vitamin transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0051748 UTP-monosaccharide-1-phosphate uridylyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0010564 regulation of cell cycle process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 1903436 regulation of mitotic cytokinetic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 1902412 regulation of mitotic cytokinesis P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0007346 regulation of mitotic cell cycle P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016703 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0055070 copper ion homeostasis P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0046146 tetrahydrobiopterin metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0031647 regulation of protein stability P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0048029 monosaccharide binding F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0006458 ’de novo’ protein folding P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0044421 extracellular region part C 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016889 endodeoxyribonuclease activity, producing 3’-phosphomonoesters F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3’-phosphomonoesters F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0048476 Holliday junction resolvase complex C 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0033202 DNA helicase complex C 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0043138 3’-5’ DNA helicase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0006511 ubiquitin-dependent protein catabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0019941 modification-dependent protein catabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0043632 modification-dependent macromolecule catabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0042908 xenobiotic transport P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0051084 ’de novo’ posttranslational protein folding P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0098732 macromolecule deacylation P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0015037 peptide disulfide oxidoreductase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016749 N-succinyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0009197 pyrimidine deoxyribonucleoside diphosphate biosynthetic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0009139 pyrimidine nucleoside diphosphate biosynthetic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0009133 nucleoside diphosphate biosynthetic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0009189 deoxyribonucleoside diphosphate biosynthetic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0046072 dTDP metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0009196 pyrimidine deoxyribonucleoside diphosphate metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0046444 FMN metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0035601 protein deacylation P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0072387 flavin adenine dinucleotide metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0033558 protein deacetylase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0015838 amino-acid betaine transport P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0015697 quaternary ammonium group transport P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0072337 modified amino acid transport P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0015696 ammonium transport P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0015929 hexosaminidase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016657 oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0045861 negative regulation of proteolysis P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0009138 pyrimidine nucleoside diphosphate metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016730 oxidoreductase activity, acting on iron-sulfur proteins as donors F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0000272 polysaccharide catabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0009250 glucan biosynthetic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0046341 CDP-diacylglycerol metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016781 phosphotransferase activity, paired acceptors F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0071265 L-methionine biosynthetic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0008028 monocarboxylic acid transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016794 diphosphoric monoester hydrolase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016211 ammonia ligase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0009008 DNA-methyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016731 oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0052592 oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0015491 cation:cation antiporter activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0004000 adenosine deaminase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0015205 nucleobase transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0015851 nucleobase transport P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0072530 purine-containing compound transmembrane transport P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0042365 water-soluble vitamin catabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0009111 vitamin catabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0072388 flavin adenine dinucleotide biosynthetic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0046443 FAD metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016880 acid-ammonia (or amide) ligase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0080135 regulation of cellular response to stress P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0015038 glutathione disulfide oxidoreductase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0051192 prosthetic group binding F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016419 S-malonyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016420 malonyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0009237 siderophore metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016259 selenocysteine metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0001887 selenium compound metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0004448 isocitrate dehydrogenase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0000989 transcription factor activity, transcription factor binding F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 2001020 regulation of response to DNA damage stimulus P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0034250 positive regulation of cellular amide metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0080134 regulation of response to stress P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0042273 ribosomal large subunit biogenesis P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0080120 CAAX-box protein maturation P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0006562 proline catabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0009065 glutamine family amino acid catabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0030414 peptidase inhibitor activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0004857 enzyme inhibitor activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0061134 peptidase regulator activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0061135 endopeptidase regulator activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0042085 5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0015203 polyamine transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016426 tRNA (adenine) methyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0046051 UTP metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0042399 ectoine metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0019634 organic phosphonate metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016827 hydrolase activity, acting on acid carbon-phosphorus bonds F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0022858 alanine transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0005294 neutral L-amino acid secondary active transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0015175 neutral amino acid transmembrane transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0044620 ACP phosphopantetheine attachment site binding F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0070037 rRNA (pseudouridine) methyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0004425 indole-3-glycerol-phosphate synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0036440 citrate synthase activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0045273 respiratory chain complex II C 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0098803 respiratory chain complex C 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0016649 oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0006083 acetate metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0032296 double-stranded RNA-specific ribonuclease activity F 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0034661 ncRNA catabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0032270 positive regulation of cellular protein metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0051247 positive regulation of protein metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0090069 regulation of ribosome biogenesis P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0015417 polyamine-transporting ATPase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004793 threonine aldolase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004637 phosphoribosylamine-glycine ligase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004515 nicotinate-nucleotide adenylyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0042256 mature ribosome assembly P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0090071 negative regulation of ribosome biogenesis P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0070038 rRNA (pseudouridine-N3-)-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0034040 lipid-transporting ATPase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004629 phospholipase C activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0015655 alanine:sodium symporter activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0009052 pentose-phosphate shunt, non-oxidative branch P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0009027 tartrate dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 1902047 polyamine transmembrane transport P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0019808 polyamine binding F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004108 citrate (Si)-synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0045281 succinate dehydrogenase complex C 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0000015 phosphopyruvate hydratase complex C 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004634 phosphopyruvate hydratase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008676 3-deoxy-8-phosphooctulonate synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0003883 CTP synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006433 prolyl-tRNA aminoacylation P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004751 ribose-5-phosphate isomerase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006438 valyl-tRNA aminoacylation P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004019 adenylosuccinate synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004821 histidine-tRNA ligase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006427 histidyl-tRNA aminoacylation P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0046429 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0002935 tRNA (adenine-C2-)-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0070040 rRNA (adenine-C2-)-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004550 nucleoside diphosphate kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006183 GTP biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0032328 alanine transport P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004832 valine-tRNA ligase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0003987 acetate-CoA ligase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0005344 oxygen transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008941 nitric oxide dioxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0051409 response to nitrosative stress P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0019491 ectoine biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0033816 diaminobutyrate acetyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0045152 antisigma factor binding F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0019700 organic phosphonate catabolic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0050194 phosphonoacetaldehyde hydrolase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0003960 NADPH:quinone reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006228 UTP biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0010033 response to organic substance P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004174 electron-transferring-flavoprotein dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0034979 NAD-dependent protein deacetylase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008198 ferrous iron binding F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0047456 2-methylisocitrate dehydratase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004350 glutamate-5-semialdehyde dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004823 leucine-tRNA ligase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006429 leucyl-tRNA aminoacylation P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0031460 glycine betaine transport P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004072 aspartate kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008124 4-alpha-hydroxytetrahydrobiopterin dehydratase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0052822 DNA-3-methylguanine glycosylase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0042277 peptide binding F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0050821 protein stabilization P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0051085 chaperone mediated protein folding requiring cofactor P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0060274 maintenance of stationary phase P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0052908 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008887 glycerate kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0031388 organic acid phosphorylation P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004827 proline-tRNA ligase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0050080 malonyl-CoA decarboxylase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0016208 AMP binding F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0019427 acetyl-CoA biosynthetic process from acetate P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0070181 small ribosomal subunit rRNA binding F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004525 ribonuclease III activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0016075 rRNA catabolic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0045727 positive regulation of translation P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0016989 sigma factor antagonist activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0033817 beta-ketoacyl-acyl-carrier-protein synthase II activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006476 protein deacetylation P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004314 [acyl-carrier-protein] S-malonyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008710 8-amino-7-oxononanoate synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0033818 beta-ketoacyl-acyl-carrier-protein synthase III activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004828 serine-tRNA ligase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0015703 chromate transport P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0016260 selenocysteine biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0097056 selenocysteinyl-tRNA(Sec) biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004450 isocitrate dehydrogenase (NADP+) activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008839 4-hydroxy-tetrahydrodipicolinate reductase F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0043916 DNA-7-methylguanine glycosylase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0052821 DNA-7-methyladenine glycosylase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0000036 ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0009143 nucleoside triphosphate catabolic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0003896 DNA primase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0009372 quorum sensing P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004638 phosphoribosylaminoimidazole carboxylase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0034028 5-(carboxyamino)imidazole ribonucleotide synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0061710 L-threonylcarbamoyladenylate synthase F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004361 glutaryl-CoA dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0043590 bacterial nucleoid C 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0051471 ectoine transmembrane transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0009022 tRNA nucleotidyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0051470 ectoine transport P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0009399 nitrogen fixation P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004356 glutamate-ammonia ligase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006542 glutamine biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004324 ferredoxin-NADP+ reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0015159 polysaccharide transmembrane transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004065 arylsulfatase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0005451 monovalent cation:proton antiporter activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0002100 tRNA wobble adenosine to inosine editing P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008251 tRNA-specific adenosine deaminase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008893 guanosine-3’,5’-bis(diphosphate) 3’-diphosphatase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0070568 guanylyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008780 acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008915 lipid-A-disaccharide synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0043531 ADP binding F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008986 pyruvate, water dikinase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0070929 trans-translation P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006574 valine catabolic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008442 3-hydroxyisobutyrate dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0009083 branched-chain amino acid catabolic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004332 fructose-bisphosphate aldolase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0061603 molybdenum cofactor guanylyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006863 purine nucleobase transport P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0003862 3-isopropylmalate dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004073 aspartate-semialdehyde dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0071266 ’de novo’ L-methionine biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004829 threonine-tRNA ligase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006435 threonyl-tRNA aminoacylation P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004363 glutathione synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006750 glutathione biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008965 phosphoenolpyruvate-protein phosphotransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0033294 ectoine binding F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004801 sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0033856 pyridoxine 5’-phosphate synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008718 D-amino-acid dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004813 alanine-tRNA ligase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006419 alanyl-tRNA aminoacylation P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0009019 tRNA (guanine-N1-)-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0052906 tRNA (guanine(37)-N(1))-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004798 thymidylate kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006233 dTDP biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0052832 inositol monophosphate 3-phosphatase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0052717 tRNA-specific adenosine-34 deaminase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0050380 undecaprenyl-diphosphatase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0035335 peptidyl-tyrosine dephosphorylation P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008897 holo-[acyl-carrier-protein] synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004563 beta-N-acetylhexosaminidase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008444 CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0033739 preQ1 synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0046857 oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008853 exodeoxyribonuclease III activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004362 glutathione-disulfide reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004141 dethiobiotin synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006434 seryl-tRNA aminoacylation P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0052833 inositol monophosphate 4-phosphatase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0003919 FMN adenylyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004015 adenosylmethionine-8-amino-7-oxononanoate transaminase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 1904823 purine nucleobase transmembrane transport P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0061711 N(6)-L-threonylcarbamoyladenine synthase F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0043772 acyl-phosphate glycerol-3-phosphate acyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0070041 rRNA (uridine-C5-)-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0036307 23S rRNA (adenine(2030)-N(6))-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004632 phosphopantothenate--cysteine ligase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004633 phosphopantothenoylcysteine decarboxylase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0015941 pantothenate catabolic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0019242 methylglyoxal biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006428 isoleucyl-tRNA aminoacylation P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008929 methylglyoxal synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006747 FAD biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008531 riboflavin kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0009398 FMN biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0009007 site-specific DNA-methyltransferase (adenine-specific) activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0032775 DNA methylation on adenine P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0009014 succinyl-diaminopimelate desuccinylase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008666 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004725 protein tyrosine phosphatase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0005345 purine nucleobase transmembrane transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004822 isoleucine-tRNA ligase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0036355 2-iminoacetate synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0015878 biotin transport P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0003979 UDP-glucose 6-dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008453 alanine-glyoxylate transaminase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0003871 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006282 regulation of DNA repair P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0000027 ribosomal large subunit assembly P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008832 dGTPase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0003856 3-dehydroquinate synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004170 dUTP diphosphatase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008836 diaminopimelate decarboxylase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004655 porphobilinogen synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0003922 GMP synthase (glutamine-hydrolyzing) activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006048 UDP-N-acetylglucosamine biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0003879 ATP phosphoribosyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0018160 peptidyl-pyrromethane cofactor linkage P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008705 methionine synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0003810 protein-glutamine gamma-glutamyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 1904047 S-adenosyl-L-methionine binding F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004642 phosphoribosylformylglycinamidine synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0052856 NADHX epimerase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0071586 CAAX-box protein processing P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004056 argininosuccinate lyase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004834 tryptophan synthase activity F 0 1 2 0 50 0 1 2 0 50 -0.568 1 1 0042450 arginine biosynthetic process via ornithine P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004657 proline dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0010133 proline catabolic process to glutamate P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004866 endopeptidase inhibitor activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0003938 IMP dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006069 ethanol oxidation P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004399 histidinol dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004635 phosphoribosyl-AMP cyclohydrolase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0019277 UDP-N-acetylgalactosamine biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008760 UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0015914 phospholipid transport P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0051903 S-(hydroxymethyl)glutathione dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004636 phosphoribosyl-ATP diphosphatase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004140 dephospho-CoA kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004592 pantoate-beta-alanine ligase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0019290 siderophore biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004370 glycerol kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006071 glycerol metabolic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0003977 UDP-N-acetylglucosamine diphosphorylase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0050568 protein-glutamine glutaminase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0031419 cobalamin binding F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004096 catalase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0046294 formaldehyde catabolic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0042744 hydrogen peroxide catabolic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008762 UDP-N-acetylmuramate dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0016805 dipeptidase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0018738 S-formylglutathione hydrolase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006784 heme a biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0048034 heme O biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008495 protoheme IX farnesyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0019134 glucosamine-1-phosphate N-acetyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004427 inorganic diphosphatase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004852 uroporphyrinogen-III synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004418 hydroxymethylbilane synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0019563 glycerol catabolic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0042743 hydrogen peroxide metabolic process P 0 0 0 0 0 0 1 1 0 100 -0.568 1 1 0004018 N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0009379 Holliday junction helicase complex C 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004746 riboflavin synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008821 crossover junction endodeoxyribonuclease activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008672 2-dehydro-3-deoxyglucarate aldolase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004643 phosphoribosylaminoimidazolecarboxamide formyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008690 3-deoxy-manno-octulosonate cytidylyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0033468 CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0003937 IMP cyclohydrolase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006011 UDP-glucose metabolic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004017 adenylate kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0043140 ATP-dependent 3’-5’ DNA helicase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0015821 methionine transport P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 1903959 regulation of anion transmembrane transport P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0015225 biotin transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0015693 magnesium ion transport P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004795 threonine synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004412 homoserine dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0009016 succinyldiaminopimelate transaminase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0003933 GTP cyclohydrolase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0003934 GTP cyclohydrolase I activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0003983 UTP:glucose-1-phosphate uridylyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0035998 7,8-dihydroneopterin 3’-triphosphate biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008661 1-deoxy-D-xylulose-5-phosphate synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0052865 1-deoxy-D-xylulose 5-phosphate biosynthetic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0003864 3-methyl-2-oxobutanoate hydroxymethyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0015976 carbon utilization P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0015109 chromate transmembrane transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0003796 lysozyme activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008750 NAD(P)+ transhydrogenase (AB-specific) activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006266 DNA ligation P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0003911 DNA ligase (NAD+) activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0007062 sister chromatid cohesion P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0009029 tetraacyldisaccharide 4’-kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0032843 hydroperoxide reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006821 chloride transport P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0005615 extracellular space C 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0010951 negative regulation of endopeptidase activity P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0070626 (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0004089 carbonate dehydratase activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0006474 N-terminal protein amino acid acetylation P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0019619 3,4-dihydroxybenzoate catabolic process P 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0005247 voltage-gated chloride channel activity F 0 1 1 0 100 0 1 1 0 100 -0.568 1 1 0008686 3,4-dihydroxy-2-butanone-4-phosphate synthase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0015716 organic phosphonate transport P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0030255 protein secretion by the type IV secretion system P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0004664 prephenate dehydratase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0017038 protein import P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0000451 rRNA 2’-O-methylation P 0 1 1 0 100 0 2 2 0 100 -0.803 1 1 0004814 arginine-tRNA ligase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0008235 metalloexopeptidase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0006420 arginyl-tRNA aminoacylation P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0004523 RNA-DNA hybrid ribonuclease activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0015604 organic phosphonate transmembrane transporter activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0006426 glycyl-tRNA aminoacylation P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0044097 secretion by the type IV secretion system P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0004088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0046295 glycolate biosynthetic process P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0004774 succinate-CoA ligase activity F 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0009450 gamma-aminobutyric acid catabolic process P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0004106 chorismate mutase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0006402 mRNA catabolic process P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0046349 amino sugar biosynthetic process P 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0050570 4-hydroxythreonine-4-phosphate dehydrogenase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0008967 phosphoglycolate phosphatase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0052834 inositol monophosphate phosphatase activity F 0 1 1 0 100 0 2 2 0 100 -0.803 1 1 0044210 ’de novo’ CTP biosynthetic process P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0008934 inositol monophosphate 1-phosphatase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0042586 peptide deformylase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0046855 inositol phosphate dephosphorylation P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0009094 L-phenylalanine biosynthetic process P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0015990 electron transport coupled proton transport P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0017148 negative regulation of translation P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0006177 GMP biosynthetic process P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0051336 regulation of hydrolase activity P 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0003725 double-stranded RNA binding F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0006306 DNA methylation P 0 1 1 0 100 0 2 2 0 100 -0.803 1 1 0046930 pore complex C 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0008641 small protein activating enzyme activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0004491 methylmalonate-semialdehyde dehydrogenase (acylating) activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0031564 transcription antitermination P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0046185 aldehyde catabolic process P 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0004549 tRNA-specific ribonuclease activity F 0 1 1 0 100 0 2 2 0 100 -0.803 1 1 0004109 coproporphyrinogen oxidase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0047429 nucleoside-triphosphate diphosphatase activity F 0 1 1 0 100 0 2 2 0 100 -0.803 1 1 0018364 peptidyl-glutamine methylation P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0005977 glycogen metabolic process P 0 1 1 0 100 0 2 1 0 200 -0.803 1 1 0036009 protein-glutamine N-methyltransferase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0015774 polysaccharide transport P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0051302 regulation of cell division P 0 1 1 0 100 0 2 2 0 100 -0.803 1 1 0006268 DNA unwinding involved in DNA replication P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0008864 formyltetrahydrofolate deformylase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0008793 aromatic-amino-acid:2-oxoglutarate aminotransferase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0004620 phospholipase activity F 0 1 1 0 100 0 2 2 0 100 -0.803 1 1 0051538 3 iron, 4 sulfur cluster binding F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0008777 acetylornithine deacetylase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0051726 regulation of cell cycle P 0 1 1 0 100 0 2 2 0 100 -0.803 1 1 0015803 branched-chain amino acid transport P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0031119 tRNA pseudouridine synthesis P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0015658 branched-chain amino acid transmembrane transporter activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0004775 succinate-CoA ligase (ADP-forming) activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0070180 large ribosomal subunit rRNA binding F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0004040 amidase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0004826 phenylalanine-tRNA ligase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0006432 phenylalanyl-tRNA aminoacylation P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0006662 glycerol ether metabolic process P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0006089 lactate metabolic process P 0 1 1 0 100 0 2 2 0 100 -0.803 1 1 0004820 glycine-tRNA ligase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0031554 regulation of DNA-templated transcription, termination P 0 1 1 0 100 0 2 2 0 100 -0.803 1 1 2001295 malonyl-CoA biosynthetic process P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0046278 3,4-dihydroxybenzoate metabolic process P 0 1 1 0 100 0 2 2 0 100 -0.803 1 1 0004049 anthranilate synthase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0015296 anion:cation symporter activity F 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0018904 ether metabolic process P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0016726 oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor F 0 1 1 0 100 0 2 2 0 100 -0.803 1 1 1902208 regulation of bacterial-type flagellum assembly P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0006085 acetyl-CoA biosynthetic process P 0 1 1 0 100 0 2 2 0 100 -0.803 1 1 0015294 solute:cation symporter activity F 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0004318 enoyl-[acyl-carrier-protein] reductase (NADH) activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0008375 acetylglucosaminyltransferase activity F 0 1 1 0 100 0 2 2 0 100 -0.803 1 1 0004347 glucose-6-phosphate isomerase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0009378 four-way junction helicase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0016748 succinyltransferase activity F 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0003908 methylated-DNA-[protein]-cysteine S-methyltransferase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0046677 response to antibiotic P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0006073 cellular glucan metabolic process P 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0072599 establishment of protein localization to endoplasmic reticulum P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0044275 cellular carbohydrate catabolic process P 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0006226 dUMP biosynthetic process P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0051184 cofactor transporter activity F 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0051181 cofactor transport P 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0005416 cation:amino acid symporter activity F 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0046080 dUTP metabolic process P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0046655 folic acid metabolic process P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0042158 lipoprotein biosynthetic process P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0005283 sodium:amino acid symporter activity F 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0005343 organic acid:sodium symporter activity F 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0015370 solute:sodium symporter activity F 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0015081 sodium ion transmembrane transporter activity F 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0004070 aspartate carbamoyltransferase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0044042 glucan metabolic process P 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 1902223 erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0016436 rRNA (uridine) methyltransferase activity F 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0052654 L-leucine transaminase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0004084 branched-chain-amino-acid transaminase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0097170 ADP-L-glycero-beta-D-manno-heptose metabolic process P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0046401 lipopolysaccharide core region metabolic process P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0060491 regulation of cell projection assembly P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0006298 mismatch repair P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0006397 mRNA processing P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0030983 mismatched DNA binding F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0009441 glycolate metabolic process P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0046165 alcohol biosynthetic process P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0034309 primary alcohol biosynthetic process P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0097171 ADP-L-glycero-beta-D-manno-heptose biosynthetic process P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0040012 regulation of locomotion P 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0009244 lipopolysaccharide core region biosynthetic process P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0017169 CDP-alcohol phosphatidyltransferase activity F 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0018198 peptidyl-cysteine modification P 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0015114 phosphate ion transmembrane transporter activity F 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0004477 methenyltetrahydrofolate cyclohydrolase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0015144 carbohydrate transmembrane transporter activity F 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0052655 L-valine transaminase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0042157 lipoprotein metabolic process P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0019184 nonribosomal peptide biosynthetic process P 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0009068 aspartate family amino acid catabolic process P 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0048583 regulation of response to stimulus P 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0052656 L-isoleucine transaminase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0033043 regulation of organelle organization P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 1902115 regulation of organelle assembly P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0031344 regulation of cell projection organization P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 1901476 carbohydrate transporter activity F 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0033365 protein localization to organelle P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 2001293 malonyl-CoA metabolic process P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0015671 oxygen transport P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0072594 establishment of protein localization to organelle P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0009002 serine-type D-Ala-D-Ala carboxypeptidase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0017150 tRNA dihydrouridine synthase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0016298 lipase activity F 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0070972 protein localization to endoplasmic reticulum P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0003842 1-pyrroline-5-carboxylate dehydrogenase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0030580 quinone cofactor methyltransferase activity F 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0046656 folic acid biosynthetic process P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0003724 RNA helicase activity F 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0046078 dUMP metabolic process P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0035337 fatty-acyl-CoA metabolic process P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0006112 energy reserve metabolic process P 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0002943 tRNA dihydrouridine synthesis P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0006047 UDP-N-acetylglucosamine metabolic process P 0 1 1 0 100 0 2 2 0 100 -0.803 1 1 0046400 keto-3-deoxy-D-manno-octulosonic acid metabolic process P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0052547 regulation of peptidase activity P 0 1 1 0 100 0 2 2 0 100 -0.803 1 1 0004400 histidinol-phosphate transaminase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0006612 protein targeting to membrane P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0006614 SRP-dependent cotranslational protein targeting to membrane P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0030162 regulation of proteolysis P 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0031555 transcriptional attenuation P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0043647 inositol phosphate metabolic process P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0006613 cotranslational protein targeting to membrane P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0004485 methylcrotonoyl-CoA carboxylase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0045047 protein targeting to ER P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0016888 endodeoxyribonuclease activity, producing 5’-phosphomonoesters F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0015669 gas transport P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0016482 cytoplasmic transport P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0016435 rRNA (guanine) methyltransferase activity F 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0008425 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0046949 fatty-acyl-CoA biosynthetic process P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0046039 GTP metabolic process P 0 1 1 0 100 0 2 2 0 100 -0.803 1 1 0000101 sulfur amino acid transport P 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0008177 succinate dehydrogenase (ubiquinone) activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0015804 neutral amino acid transport P 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0008988 rRNA (adenine-N6-)-methyltransferase activity F 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0033037 polysaccharide localization P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0015846 polyamine transport P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0019294 keto-3-deoxy-D-manno-octulosonic acid biosynthetic process P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor F 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0004004 ATP-dependent RNA helicase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0034249 negative regulation of cellular amide metabolic process P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0048872 homeostasis of number of cells P 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0048874 homeostasis of number of cells in a free-living population P 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0030060 L-malate dehydrogenase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0005319 lipid transporter activity F 0 1 1 0 100 0 2 1 0 200 -0.803 1 1 0071545 inositol phosphate catabolic process P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0046838 phosphorylated carbohydrate dephosphorylation P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0052745 inositol phosphate phosphatase activity F 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0009712 catechol-containing compound metabolic process P 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0018958 phenol-containing compound metabolic process P 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0051998 protein carboxyl O-methyltransferase activity F 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0009438 methylglyoxal metabolic process P 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0044208 ’de novo’ AMP biosynthetic process P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0040029 regulation of gene expression, epigenetic P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0044728 DNA methylation or demethylation P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0006305 DNA alkylation P 0 0 0 0 0 0 2 2 0 100 -0.803 1 1 0004794 L-threonine ammonia-lyase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0031123 RNA 3’-end processing P 0 0 0 0 0 0 2 1 0 200 -0.803 1 1 0006814 sodium ion transport P 0 2 2 0 100 0 2 2 0 100 -0.803 1 1 0003852 2-isopropylmalate synthase activity F 0 2 2 0 100 0 2 2 0 100 -0.803 1 1