Week 7 - Revision history

Kdahlquist: removed under construction

2015-10-08T20:39:31Z

removed under construction

2015-10-08T20:39:13Z

‎Individual Journal Assignment: assigned homework partners

2015-10-08T20:12:28Z

‎Overview: added purpose

2015-10-08T20:09:46Z

‎Answer the following Discovery Questions from Chapter 4: tweaked header

2015-10-08T20:06:43Z

‎Read: added data one slides to reading

2015-10-08T20:04:36Z

‎Shared Journal Assignment: fixed spelling

2015-10-08T20:04:19Z

‎Shared Journal Assignment: fixed link

← Older revision		Revision as of 20:39, 8 October 2015
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	'''This journal entry is due on Tuesday, October 20, at midnight PDT.''' ''(Monday night/Tuesday morning)''		'''This journal entry is due on Tuesday, October 20, at midnight PDT.''' ''(Monday night/Tuesday morning)''
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−	~~{{ Under Construction }}~~

	== Overview ==		== Overview ==

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 **'''''Note: you can easily fulfill all of these links by adding them to your template and then using your template on your journal entry.'''''
 * For this week only, an '''''electronic laboratory notebook''''' is not required.  It is enough to answer the questions posed.
 === Introduction to DNA Microarrays ===

← Older revision		Revision as of 20:12, 8 October 2015
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	The purpose of this assignment is:		The purpose of this assignment is:
		+
		+	# to acquire foundational knowledge about how DNA microarrays are used to measure gene expression.
		+	# to connect the research methods we are learning about in class with real world examples of fraud.

	== Individual Journal Assignment ==		== Individual Journal Assignment ==

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 * DeRisi, J.L., Iyer, V.R., and Brown, P.O.  (1997)  [http://www.sciencemag.org/content/278/5338/680.full Exploring the Metabolic and Genetic Control of Gene Expression on a Genomic Scale.]  ''Science'' 278: 680-686.
-==== Answer the following Discovery Questions from Chapter 4 ====
+==== Answer the following Discovery Questions from Campbell & Heyer Chapter 4 ====
 Answer the following questions related to Chapter 4 of Campbell & Heyer (2003).  Note that some of the questions below have been reworded from the Discovery Questions in the book:

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 * [http://www.bio.davidson.edu/courses/genomics/chip/chip.html Microarray animation]
 * Brown, P.O. & Botstein, D. (1999) [http://www.nature.com/ng/journal/v21/n1s/full/ng0199supp_33.html Exploring the new world of the genome with DNA microarrays] ''Nature Genetics''  21: 33-37.
 * Campbell, A.M. and Heyer, L.J. (2003), “Chapter 4:  Basic Research with DNA Microarrays”, in ''Discovering Genomics, Proteomics, and Bioinformatics'', Cold Spring Harbor Laboratory Press, pp. 107-124. ([https://mylmuconnect.blackboard.com/webapps/blackboard/content/listContentEditable.jsp?content_id=_1103141_1&course_id=_62090_1 Available on MyLMUConnect])
 * DeRisi, J.L., Iyer, V.R., and Brown, P.O.  (1997)  [http://www.sciencemag.org/content/278/5338/680.full Exploring the Metabolic and Genetic Control of Gene Expression on a Genomic Scale.]  ''Science'' 278: 680-686.

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 * Answer the following questions:
-** Were you aware of the Duke case of research fraud before viewing this video?  Were you aware of the Volkswagon case?
+** Were you aware of the Duke case of research fraud before viewing this video?  Were you aware of the Volkswagen case?
 ** What are your initial reactions to hearing about both of these?
 ** What role did data sharing play in uncovering both of these frauds?

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 === Read ===
-* [Volkswagen and the Era of Cheating Software ''Volkswagen and the Era of Cheating Software'' by Zeynep Tufekci, New York Times, September 23, 2015.]
+* [http://www.nytimes.com/2015/09/24/opinion/volkswagen-and-the-era-of-cheating-software.html?_r=0 ''Volkswagen and the Era of Cheating Software'' by Zeynep Tufekci, New York Times, September 23, 2015.]
 === Reflection ===