Difference between revisions of "Week 2"

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'''This journal entry is due on Tuesday, September 15, at midnight PDT.''' ''(Monday night/Tuesday morning)''
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= Team Information & Links =
  
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<!--{{ Under Construction }}-->
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{{Template:Class Whoopers}}
  
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== Overview ==
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=Weekly Updates=
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==Week 11==
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===Goals===
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* For all:
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** Outline your assigned paper on your user page and include a list of 10 defined terms from the paper.
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*Nicole & Brandon
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**Prepare Journal Club presentation on the designated genome sequencing article
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**Slides Due: by midnight, Tuesday, November 17
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**Presentation Date: Tuesday, November 24
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*Lena & Mahrad
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**Prepare Journal Club presentation on the designated microarray paper
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**Slides Due: by midnight, Tuesday, November 17
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**Presentation Date: Tuesday, November 17
  
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The purpose of this assignment is:
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===Progress===
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*Nicole Anguiano (Coder):
 +
*Brandon Klein (QA):
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*Lena Olufson (GennMAPP):
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*Mahrad Saeedi (GennMAPP):
  
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* To familiarize yourself with the decoding the genetic code in a "paper and pencil" exercise, to motivate using a computer to do such work.
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=== Meetings! ===
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* To begin comparing the genetic code to a computer code.
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* TBD
  
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== Individual Journal Assignment ==
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==Week 10==
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===Goals===
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* For all:
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** Create an annotated bibliography including one genome sequencing paper and two microarray experiments for Bordetella pertussis
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** Create/update team page & compile group annotated bibliography
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** Assignment due date: Midnight Tuesday, November 10
  
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* Store this journal entry as "''username'' Week 2" (i.e., this is the text to place between the square brackets when you link to this page).
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===Progress===
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* Link from your user page to this Assignment page.
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*All group members created annotated bibliographies and compiled them on the newly created group page.
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* Link to your journal entry from your user page.
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* Link back from your journal entry to your user page.
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* Don't forget to add the "Journal Entry" category to the end of your wiki page.
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**'''''Note: you can easily fulfill all of these links by adding them to your template and then using your template on your journal entry.'''''
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* For your assignment this week, you will keep an '''''electronic laboratory notebook''''' on your individual wiki page.  An electronic laboratory notebook records all the manipulations you perform on the data and the answers to the questions throughout the protocol. Like a paper lab notebook found in a wet lab, it should contain enough information so that you or someone else could reproduce what you did using only the information from the notebook.
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=== Homework Partners ===
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=== Meetings! ===
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* Monday, November 9, 8pm-9pm, Seaver 120
  
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For most weeks in the semester, you will be assigned a "homework partner" from the complementary biology or computer science discipline. You will be expected to consult with your partner, sharing your domain expertise, in order to complete the assignment. However, unless otherwise stated, each partner must submit his or her own work as the individual journal entry (direct copies of each other's work is not allowed). Homework partners for this week are:
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= Deliverables =
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*GenMAPP Gene Database for assigned species (.gdb)
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*ReadMe file to accompany the Gene Database (.pdf)
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*Sample ReadMe in Word format: ReadMe_Vc-Std_External_20131122.zip
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*Include Gene Database Schema diagram in ReadMe
 +
*Sample schema in Adobe Illustrator format: Vibrio_schema_20101022.zip
 +
*Gene Database Testing Report for final submitted Gene Database (print from wiki to .pdf file)
 +
*Processed and analyzed DNA microarray dataset (.xls)
 +
*GenMAPP Expression Dataset file (.gex)
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*Filtered MAPPFinder Results (.xls)
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*Sample MAPP file of a relevant biological pathway for your species (.mapp)
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*Group Report describing the creation of the Gene Database and the biological analysis of the data (.doc or .pdf)
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*PowerPoint presentation (.ppt, given on Tuesday, December 15)
  
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* Mary Alverson, Elena Olufson
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= Annotated Bibliography =
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* Nicole Anguiano, Brandon Litvak
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== Genome Sequencing Paper ==
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* Brandon Klein, Emily Simso
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* Josh Kuroda, Veronica Pacheco
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* Ron Legaspi, Trixie Roque
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* Mahrad Saeedi, Anindita Varshneya
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* Jake Woodlee, Kevin Wyllie
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* Erich Yanoschik, Kristen Zebrowski
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<!--=== Wiki Catch-up ===
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Neither of these papers is the ''first'' to report the genome sequence of ''B. pertussis.''  The paper that you will want to use is [http://www.nature.com/ng/journal/v35/n1/full/ng1227.html this one].  I found it by looking at the introduction and references of the Zhang et. al (2011) paper.  For your Week 11 assignment, please remove your annotated bibliography entries for the two papers below and create one for this new paper by Parkhill et al. (2003).  You will use the Parkhill paper for your project.  ''&mdash; [[User:Kdahlquist|Kdahlquist]] ([[User talk:Kdahlquist|talk]]) 09:54, 10 November 2015 (PST)''
  
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If you missed practicing any wiki skills or doing any other tasks from [[Week 1]], wrap them up this week.-->
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Note: revise/complete this citation
  
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=== The Genetic Code ===
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*Parkhill, J., Sebaihia, M., Preston, A., Murphy, L. D., et al. (2003). Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica. Nature genetics, 35(1), 32-40. doi:10.1038/ng1227
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* PubMed Abstract:  http://www.ncbi.nlm.nih.gov/pubmed/12910271
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* PubMed Central:  Not available on PubMed Central
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* Publisher Full Text (HTML):  http://www.nature.com/ng/journal/v35/n1/full/ng1227.html
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* Publisher Full Text (PDF):  http://www.nature.com/ng/journal/v35/n1/pdf/ng1227.pdf
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* Copyright: ©2003 Nature Publishing Group (information found on PDF version of article). This article is not Open Access, but it is freely available 6 months after publication
 +
* Publisher: Nature Publishing Group (for profit?)
 +
* Availability: in print and online
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* Did LMU pay a fee for this article: Yes, LMU pays a subscription fee for access to the journal ''Nature Genetics''.
  
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* Write out the complementary strand of DNA below the strand shown and be sure to label the 5’ and 3’ ends of the complementary strand.
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== Microarray Paper ==
  
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  5’-cgtatgctaataccatgttccgcgtataacccagccgccagttccgctggcggcatttta-3’
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This paper is suitable for your project. ''&mdash; [[User:Kdahlquist|Kdahlquist]] ([[User talk:Kdahlquist|talk]]) 10:04, 10 November 2015 (PST)''
  
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* There are six possible reading frames in double-stranded DNA. Using the [http://en.wikipedia.org/wiki/Genetic_code#RNA_codon_table genetic code], translate all possible reading frames of this DNA sequence, keeping in mind the following rules.
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Hoo, R., Lam, J.H., Huot, L., Pant, A., Li, R., Hot, D., & Alonso, S. (2014). Evidence for a Role of the Polysaccharide Capsule Transport Proteins in Pertussis Pathogenesis. PLoS ONE, 9(12):e115243. doi: 10.1371/journal.pone.0115243
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** In RNA, the T becomes a U, so everywhere you see a T in the sequence, read it as a U.
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* PubMed Abstract: http://www.ncbi.nlm.nih.gov/pubmed/25501560
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** The genetic code is read in the 5’ to 3’ direction.
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* PubMed Central: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264864/
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** Use the single-letter abbreviations for the amino acids because that is what is commonly used by computer programs.
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* Publisher Full Text (HTML): http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0115243
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* Wiki Hint: if you start your line with a single space character, it will appear in the grey box surrounded by the dashed line as shown above.
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* Publisher Full Text (PDF): http://www.plosone.org/article/fetchObject.action?uri=info:doi/10.1371/journal.pone.0115243&representation=PDF
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* Which of the reading frames (if any) of the reading frames you translated is an ''open reading frame'', i.e., does not contain a stop codon?
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* Copyright: © 2014 Hoo et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. (info found [http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0115243 here])
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** By convention, the top strand frames are called +1, +2, +3, reading 5' to 3' and the bottom strand frames are called -1, -2, -3, reading 5' to 3'.
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* Publisher: PLOS ONE (respected open access organization)
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* Availability: online only
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* Did LMU pay a fee for this article: no
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* Web site where the data resides: [http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE62088 NCBI GEO data]
  
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== Shared Journal Assignment ==
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<!--#2
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*Brickman, T. J., Cummings, C. A., Liew, S.-Y., Relman, D. A., & Armstrong, S. K. (2011). Transcriptional Profiling of the Iron Starvation Response in Bordetella pertussis Provides New Insights into Siderophore Utilization and Virulence Gene Expression . Journal of Bacteriology, 193(18), 4798–4812. http://doi.org/10.1128/JB.05136-11
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* ArrayExpress Abstract: https://www.ebi.ac.uk/arrayexpress/experiments/E-MEXP-3263/?keywords=&organism=Bordetella+pertussis&exptype%5B%5D=%22rna+assay%22&exptype%5B%5D=%22array+assay%22&array=
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* PubMed Central:  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC532028/
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*PubMed Abstract: http://www.ncbi.nlm.nih.gov/pubmed/?term=Transcriptional+Profiling+of+the+Iron+Starvation+Response+in+Bordetella+pertussis+Provides+New+Insights+into+Siderophore+Utilization+and+Virulence+Gene+Expression
 +
* Publisher Full Text (HTML): http://jb.asm.org/content/193/18/4798.full
 +
* Publisher Full Text (PDF):  http://jb.asm.org/content/193/18/4798.full.pdf+html
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* Copyright:  2011 by the American Society for Microbiology
 +
* Publisher:  Journal of Bacteriology
 +
* Availability:  in print and online
 +
* Did LMU pay a fee for this article: yes
 +
*Link to where the microarray data resides: https://www.ebi.ac.uk/arrayexpress/experiments/E-MEXP-3263/?keywords=&organism=Bordetella+pertussis&exptype%5B%5D=%22rna+assay%22&exptype%5B%5D=%22array+assay%22&array=
  
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* Store your journal entry in the shared [[Class Journal Week 2]] page. If this page does not exist yet, go ahead and create it (congratulations on getting in first&nbsp;''':)'''&nbsp;)
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#3
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* Link to your journal entry from your user page.
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King, A. J., van der Lee, S., Mohangoo, A., van Gent, M., van der Ark, A., & van de Waterbeemd, B. (2013). Genome-Wide Gene Expression Analysis of Bordetella pertussis Isolates Associated with a Resurgence in Pertussis: Elucidation of Factors Involved in the Increased Fitness of Epidemic Strains. PLoS ONE, 8(6): e66150. doi: 10.1371/journal.pone.0066150
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* Link back from the journal entry to your user page.
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* PubMed Abstract:  http://www.ncbi.nlm.nih.gov/pubmed/23776625
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**'''''NOTE: you can easily fulfill the links part of these instructions by adding them to your template and using the template on your user page.'''''
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* PubMed Central:  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679012/
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* Sign your portion of the journal with the standard wiki signature shortcut (<code><nowiki>~~~~</nowiki></code>).
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* Publisher Full Text (HTML):  http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0066150
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* Add the "Journal Entry" and "Shared" categories to the end of the wiki page (if someone has not already done so).
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* Publisher Full Text (PDF): http://www.plosone.org/article/fetchObject.action?uri=info:doi/10.1371/journal.pone.0066150&representation=PDF
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* Copyright: © 2013 King et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. (info found [http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0066150 here])
 +
* Publisher: PLOS ONE (respected open access organization)
 +
* Availability: online only
 +
* Did LMU pay a fee for this article: no
 +
* Web site where the data resides: [http://www.ebi.ac.uk/arrayexpress/experiments/E-MTAB-1594/samples/?keywords=Bordetella+pertussis&organism=Bordetella+pertussis&exptype%5B%5D=%22rna+assay%22&exptype%5B%5D=%22array+assay%22&array=&s_page=1&s_pagesize=100 EBI ArrayExpress Data]
  
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=== Read ===
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#4 (note, all of the papers from this point on involve additional species other than Bordetella pertussis)
  
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* [http://www.ncbi.nlm.nih.gov/books/NBK21121/#A5818 Brown, T.A. (2002) ''Genomes 2'', Ch. 3.3.2: The link between the transcriptome and the proteome] (freely available on NCBI Bookshelf)
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* Cummings, C. A., Bootsma, H. J., Relman, D. A., & Miller, J. F. (2006). Species-and strain-specific control of a complex, flexible regulon by Bordetella BvgAS. Journal of bacteriology, 188(5), 1775-1785.
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* Nirenberg, M. (2004) Deciphering the Genetic Code&mdash;a Personal Account. ''Trends in Biochemical Sciences'' 29:  46-54. (on [https://mylmuconnect.blackboard.com/webapps/portal/frameset.jsp?tab_tab_group_id=_2_1url=%2Fwebapps%2Fblackboard%2Fexecute%2Flauncher%3Ftype%3DCourse%26id%3D_35506_1%26url%3D MyLMUConnect])
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* ArrayExpress Abstract: https://www.ebi.ac.uk/arrayexpress/experiments/E-TABM-29/?keywords=&organism=Bordetella+pertussis&exptype%5B%5D=%22rna+assay%22&exptype%5B%5D=%22array+assay%22&array=
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* Kaji, A., Kaji, H. (2004) The history of deciphering the genetic code: setting the record straight. ''Trends in Biochemical Sciences'' 29: 293.
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* PubMed Central:  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1426559/
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* Moody, G. (2004) ''Digital Code of Life'', Chapter 1, Hoboken, New Jersey: John Wiley & Sons, pp. 1-9. (on [https://mylmuconnect.blackboard.com/webapps/portal/frameset.jsp?tab_tab_group_id=_2_1url=%2Fwebapps%2Fblackboard%2Fexecute%2Flauncher%3Ftype%3DCourse%26id%3D_35506_1%26url%3D MyLMUConnect])
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*PubMed Abstract:http://www.ncbi.nlm.nih.gov/pubmed/?term=Species-+and+Strain-Specific+Control+of+a+Complex%2C+Flexible+Regulon+by+Bordetella+BvgAS
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* Hayes, B. (2004) Ode to the Code, ''American Scientist'' 92: 494-498. (on [https://mylmuconnect.blackboard.com/webapps/portal/frameset.jsp?tab_tab_group_id=_2_1url=%2Fwebapps%2Fblackboard%2Fexecute%2Flauncher%3Ftype%3DCourse%26id%3D_35506_1%26url%3D MyLMUConnect])
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* Publisher Full Text (HTML): http://jb.asm.org/content/188/5/1775.full
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* Publisher Full Text (PDF):  http://jb.asm.org/content/188/5/1775.full.pdf+html
 +
* Copyright:  2006 by the American Society for Microbiology
 +
* Publisher:  Journal of Bacteriology
 +
* Availability:  in print and online
 +
* Did LMU pay a fee for this article: yes
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*Link to where the microarray data resides: https://www.ebi.ac.uk/arrayexpress/experiments/E-TABM-29/?keywords=&organism=Bordetella+pertussis&exptype%5B%5D=%22rna+assay%22&exptype%5B%5D=%22array+assay%22&array=
  
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=== Reflect ===
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#5
  
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# What is the biggest discovery that I made from these readings?
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* Brinig, M., Register, K., Ackermann, M., & Relman, D. (2006). Genomic features of Bordetella parapertussis clades with distinct host species specificity. Genome Biology, 7(9). doi:doi:10.1186/gb-2006-7-9-r81
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# What part of the readings did I understand the least?
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* PubMed Abstract:  http://www.ncbi.nlm.nih.gov/pubmed/16956413?dopt=Abstract&holding=f1000,f1000m,isrctn
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# What is the relationship between the genetic code and a computer code?
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* PubMed Central:  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794550/
 +
* Publisher Full Text (HTML):  http://www.genomebiology.com/2006/7/9/R81
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* Publisher Full Text (PDF):  http://www.genomebiology.com/content/pdf/gb-2006-7-9-r81.pdf
 +
* Copyright: Brinig et al.; licensee BioMed Central Ltd. (information found on the article); open access
 +
* Publisher:  BioMed Central Ltd (for-profit publisher)
 +
* Availability:  online
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* Did LMU pay a fee for this article: no
 +
# What experiment was performed?  What was the "treatment" and what was the "control" in the experiment?
 +
# Were replicate experiments of the "treatment" and "control" conditions conducted? Were these biological or technical replicates?  How many of each?
 +
* Link to microarray data: https://www.ebi.ac.uk/arrayexpress/experiments/E-TABM-95/
  
−
[[Category:Assignment]]
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#6
 +
 
 +
* Cummings, C., Bootsma, H., Relman, D., & Miller, J. (2006). Species- and Strain-Specific Control of a Complex, Flexible Regulon by Bordetella BvgAS. Journal of Bacteriology, 188(5), 1775-1785. doi:doi: 10.1128/JB.188.5.1775-1785.2006
 +
* PubMed Abstract: http://www.ncbi.nlm.nih.gov/pubmed/16484188?dopt=Abstract
 +
* PubMed Central:  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1426559/
 +
* Publisher Full Text (HTML):  http://jb.asm.org/content/188/5/1775.full
 +
* Publisher Full Text (PDF):  http://jb.asm.org/content/188/5/1775.full.pdf
 +
* Copyright: American Society for Microbiology; open access
 +
* Publisher:  American Society for Microbiology (professional organization for scientists)
 +
* Availability:  online and in print
 +
* Did LMU pay a fee for this article: no
 +
# What experiment was performed?  What was the "treatment" and what was the "control" in the experiment?
 +
# Were replicate experiments of the "treatment" and "control" conditions conducted?  Were these biological or technical replicates?  How many of each?
 +
* Link to microarray data: https://www.ebi.ac.uk/arrayexpress/experiments/E-TABM-28/
 +
 
 +
#7
 +
 
 +
*King, A. J., van Gorkom, T., Pennings, J. L., van der Heide, H. G., He, Q., Diavatopoulos, D., … Mooi, F. R. (2010). Correction: Comparative genomic profiling of Dutch clinical Bordetella pertussis isolates using DNA microarrays: identification of genes absent from epidemic strains. BMC Genomics, 11, 196. http://doi.org/10.1186/1471-2164-11-196
 +
* PubMed Abstract:  http://www.biomedcentral.com/1471-2164/9/311#abs
 +
* PubMed Central: <http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481270/>
 +
* Publisher Full Text (HTML):  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481270/
 +
* Publisher Full Text (PDF): <http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481270/pdf/1471-2164-9-311.pdf>
 +
* Copyright:  © 2008 King et al; licensee BioMed Central Ltd.This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
 +
* Publisher: BMC Genomics
 +
* Availability: online access
 +
* Did LMU pay a fee for this article: no
 +
 
 +
#8
 +
 
 +
*Nakamura, M. M., Liew, S.-Y., Cummings, C. A., Brinig, M. M., Dieterich, C., & Relman, D. A. (2006). Growth Phase- and Nutrient Limitation-Associated Transcript Abundance Regulation in Bordetella pertussis  . Infection and Immunity, 74(10), 5537–5548. http://doi.org/10.1128/IAI.00781-06
 +
* PubMed Abstract:  <http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1594893/?report=reader#__abstractid499869title>
 +
* PubMed Central: <http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1594893/>
 +
* Publisher Full Text (HTML): <http://iai.asm.org/content/74/10/5537.full>
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* Publisher Full Text (PDF):  <http://iai.asm.org/content/74/10/5537.full.pdf+html>
 +
* Copyright: © 2006, American Society for Microbiology
 +
* Publisher: Infection and Immunity
 +
* Availability: online access
 +
* Did LMU pay a fee for this article: no!-->

Revision as of 23:52, 12 November 2015

Team Information & Links

GenMAPP Analysis of Bordetella pertussis Microarray Data

Gene Database Project Links
Overview Deliverables Reference Format Guilds Project Manager GenMAPP User Quality Assurance Coder
Teams Heavy Metal HaterZ The Class Whoopers GÉNialOMICS Oregon Trail Survivors

Journal Entries

Class Whoopers Individual Journal Entries
Brandon Klein Week 11 Week 12 Week 14 Week 15
Lena Olufson Week 11 Week 12 Week 14 Week 15
Mahrad Saeedi Week 11 Week 12 Week 14 Week 15
Team Entries Week 11 Week 12 Week 14 Week 15

Group Members

Team Weekly Assignments

  • Week 10 Creation of page and combined annotated bibliography (midnight 11/10)
  • Week 11 (midnight 11/17)
  • Week 12 (midnight 11/24)
  • Week 14 (midnight 12/8)
  • Week 15 (midnight 12/15)

Weekly Updates

Week 11

Goals

  • For all:
    • Outline your assigned paper on your user page and include a list of 10 defined terms from the paper.
  • Nicole & Brandon
    • Prepare Journal Club presentation on the designated genome sequencing article
    • Slides Due: by midnight, Tuesday, November 17
    • Presentation Date: Tuesday, November 24
  • Lena & Mahrad
    • Prepare Journal Club presentation on the designated microarray paper
    • Slides Due: by midnight, Tuesday, November 17
    • Presentation Date: Tuesday, November 17

Progress

  • Nicole Anguiano (Coder):
  • Brandon Klein (QA):
  • Lena Olufson (GennMAPP):
  • Mahrad Saeedi (GennMAPP):

Meetings!

  • TBD

Week 10

Goals

  • For all:
    • Create an annotated bibliography including one genome sequencing paper and two microarray experiments for Bordetella pertussis
    • Create/update team page & compile group annotated bibliography
    • Assignment due date: Midnight Tuesday, November 10

Progress

  • All group members created annotated bibliographies and compiled them on the newly created group page.

Meetings!

  • Monday, November 9, 8pm-9pm, Seaver 120

Deliverables

  • GenMAPP Gene Database for assigned species (.gdb)
  • ReadMe file to accompany the Gene Database (.pdf)
  • Sample ReadMe in Word format: ReadMe_Vc-Std_External_20131122.zip
  • Include Gene Database Schema diagram in ReadMe
  • Sample schema in Adobe Illustrator format: Vibrio_schema_20101022.zip
  • Gene Database Testing Report for final submitted Gene Database (print from wiki to .pdf file)
  • Processed and analyzed DNA microarray dataset (.xls)
  • GenMAPP Expression Dataset file (.gex)
  • Filtered MAPPFinder Results (.xls)
  • Sample MAPP file of a relevant biological pathway for your species (.mapp)
  • Group Report describing the creation of the Gene Database and the biological analysis of the data (.doc or .pdf)
  • PowerPoint presentation (.ppt, given on Tuesday, December 15)

Annotated Bibliography

Genome Sequencing Paper

Neither of these papers is the first to report the genome sequence of B. pertussis. The paper that you will want to use is this one. I found it by looking at the introduction and references of the Zhang et. al (2011) paper. For your Week 11 assignment, please remove your annotated bibliography entries for the two papers below and create one for this new paper by Parkhill et al. (2003). You will use the Parkhill paper for your project. — Kdahlquist (talk) 09:54, 10 November 2015 (PST)

Note: revise/complete this citation

  • Parkhill, J., Sebaihia, M., Preston, A., Murphy, L. D., et al. (2003). Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica. Nature genetics, 35(1), 32-40. doi:10.1038/ng1227
  • PubMed Abstract: http://www.ncbi.nlm.nih.gov/pubmed/12910271
  • PubMed Central: Not available on PubMed Central
  • Publisher Full Text (HTML): http://www.nature.com/ng/journal/v35/n1/full/ng1227.html
  • Publisher Full Text (PDF): http://www.nature.com/ng/journal/v35/n1/pdf/ng1227.pdf
  • Copyright: ©2003 Nature Publishing Group (information found on PDF version of article). This article is not Open Access, but it is freely available 6 months after publication
  • Publisher: Nature Publishing Group (for profit?)
  • Availability: in print and online
  • Did LMU pay a fee for this article: Yes, LMU pays a subscription fee for access to the journal Nature Genetics.

Microarray Paper

This paper is suitable for your project. — Kdahlquist (talk) 10:04, 10 November 2015 (PST)

Hoo, R., Lam, J.H., Huot, L., Pant, A., Li, R., Hot, D., & Alonso, S. (2014). Evidence for a Role of the Polysaccharide Capsule Transport Proteins in Pertussis Pathogenesis. PLoS ONE, 9(12):e115243. doi: 10.1371/journal.pone.0115243


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