**Coevolution with the expansion of ''Homo sapiens''.
 
**Coevolution with the expansion of ''Homo sapiens''.
 
**Higher transmission rates no longer necessitate environmental survival (e.g. loss of capsule) or limited damage to the host (e.g. pertussis toxin).
 
**Higher transmission rates no longer necessitate environmental survival (e.g. loss of capsule) or limited damage to the host (e.g. pertussis toxin).
 +
'''Overall Impact'''
 +
This paper sequenced the genomes of ''B. pertussis'', ''B. parapertussis'', and ''B. bronchiseptica''; provided evidence for the common ancestry of these organisms; identified new information regarding their capsules; and proposed the genetic roots of increased virulence in the two strains that are human pathogens. These findings can be applied to genomic analyses of future pathogens to assess virulence.
    
====Methods====
 
====Methods====
 
'''DNA Preparation and Sequencing'''
 
'''DNA Preparation and Sequencing'''
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#0 /apps/xmlpipedb/biodb/fall2015/includes/diff/DairikiDiff.php(544): DiffEngine->diag()
#1 /apps/xmlpipedb/biodb/fall2015/includes/diff/DairikiDiff.php(344): DiffEngine->compareSeq()
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#13 /apps/xmlpipedb/biodb/fall2015/includes/diff/DifferenceEngine.php(632): DifferenceEngine->getDiff()
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#18 /apps/xmlpipedb/biodb/fall2015/includes/MediaWiki.php(395): ViewAction->show()
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#22 /apps/xmlpipedb/biodb/fall2015/index.php(44): MediaWiki->run()
#23 {main}