**Suggests that the ''Bordetella'' variable host specificity may be influenced by changes in this receptor-ligand interaction.
 
**Suggests that the ''Bordetella'' variable host specificity may be influenced by changes in this receptor-ligand interaction.
 
*Autotransporter protein variation.
 
*Autotransporter protein variation.
**Table 2 demonstrate differing autotransporter complements amongst the three species.
+
**'''Table 2''' lists the autotransporter proteins encoded for by ''B. pertussis'', ''B. parapertussis'', and ''B. bronchiseptica''. This table demonstrates that autotransporter complements differ amongst the three species.
 
** ''B. pertussis'' and ''B. parapertussis'' have fewer genes and more pseudogenes.
 
** ''B. pertussis'' and ''B. parapertussis'' have fewer genes and more pseudogenes.
 
**May also impact host specificity.
 
**May also impact host specificity.
 
*Siderophore similarities and variation.
 
*Siderophore similarities and variation.
 
**All three species contain operons for the siderophore alcaligin, suggesting they scavenge iron from their hosts.
 
**All three species contain operons for the siderophore alcaligin, suggesting they scavenge iron from their hosts.
 +
**'''Table 3''' lists the TonB-dependent ferric complex receptors encoded for by ''B. pertussis'', ''B. parapertussis'', and ''B. bronchiseptica''. This table demonstrates that each species codes for up to 16 of these molecules, which also suggests iron scavenging behavior.
 
** ''B. pertussis'' and ''B. parapertussis'' have fewer genes and more pseudogenes that code for siderophores.
 
** ''B. pertussis'' and ''B. parapertussis'' have fewer genes and more pseudogenes that code for siderophores.
 
**Lacking necessary siderophores may influence host specificity.
 
**Lacking necessary siderophores may influence host specificity.
 
**Synonymous substitution frequency values were calculated from orthologous gene pairs.
 
**Synonymous substitution frequency values were calculated from orthologous gene pairs.
 
**Ages of divergence were estimated.
 
**Ages of divergence were estimated.
 +
 +
====Preliminary Presentation====
 +
File Link: [[File:Genomepaper cw20151116.pdf]]
    
==''Bordetella Pertussis'' Model Organism Database==
 
==''Bordetella Pertussis'' Model Organism Database==
 
#I confirmed the GeneDB website as the ''Bordetella pertussis'' MOD with Dr. Dahlquist.
 
#I confirmed the GeneDB website as the ''Bordetella pertussis'' MOD with Dr. Dahlquist.
 
===Assessing the GeneDB MOD for ''Bordetella pertussis''===
 
===Assessing the GeneDB MOD for ''Bordetella pertussis''===
 +
'''Citation for GeneDB:'''
 +
*'''Logan-Klumpler, F. J., De Silva, N., Boehme, U., et al. (2012). GeneDB—an annotation database for pathogens. Nucleic acids research, 40(D1), D98-D108. doi: 10.1093/nar/gkr1032'''
 
# What types of data can be found in the database (sequence, structures, annotations, etc.); is it a primary or “meta” database; is it curated electronically, manually [in-house], or manually [community])?
 
# What types of data can be found in the database (sequence, structures, annotations, etc.); is it a primary or “meta” database; is it curated electronically, manually [in-house], or manually [community])?
 
#*GeneDB contains ''Bordetella pertussis'' gene sequences, locations, extensive annotations, and information regarding the proteins that the genes code for such as the proteins' lengths in amino acids and molecular masses.
 
#*GeneDB contains ''Bordetella pertussis'' gene sequences, locations, extensive annotations, and information regarding the proteins that the genes code for such as the proteins' lengths in amino acids and molecular masses.
#*GeneDB is a _______ database.
+
#*GeneDB is a primary database [http://nar.oxfordjournals.org/content/40/D1/D98.full].
 
#*GeneDB undergoes extensive manual [in-house] curation [http://www.genedb.org/Page/aboutUs]. For ''Bordetella pertussis'', manual curation is directed by Dr. Julian Parkhill.
 
#*GeneDB undergoes extensive manual [in-house] curation [http://www.genedb.org/Page/aboutUs]. For ''Bordetella pertussis'', manual curation is directed by Dr. Julian Parkhill.
 
# What individual or organization maintains the database?  
 
# What individual or organization maintains the database?  
 
#* The only link to an external site that is not hosted by the Sanger Institute is to the [https://en.wikipedia.org/wiki/Bordetella_pertussis ''Bordetella pertussis'' Wikipedia Page].
 
#* The only link to an external site that is not hosted by the Sanger Institute is to the [https://en.wikipedia.org/wiki/Bordetella_pertussis ''Bordetella pertussis'' Wikipedia Page].
 
#* No links to other databases are present. All of the tools presented by GeneDB such as their BLAST tool are entirely self-contained.
 
#* No links to other databases are present. All of the tools presented by GeneDB such as their BLAST tool are entirely self-contained.
# Can the information be downloaded?
+
# Can the information be downloaded?  
#*There is a FTP link to the sequence data for ''Bordetella pertussis'' on the [http://www.genedb.org/Homepage/Bpertussis Main Page].
+
#*Information regarding genes and the proteins that they code for can be dowloaded directly from GeneDB. The download page, however, it somewhat tricky to access. To do so, follow these instructions accessed from the [http://www.genedb.org/Page/genedbFAQ FAQ Page]:
 +
#**[[File:GeneDB Download Instructions.png]]
 +
#*Additionally, there is a FTP link to the genome sequence data for ''Bordetella pertussis'' on the [http://www.genedb.org/Homepage/Bpertussis Main Page].
 
#* In what file formats?
 
#* In what file formats?
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