Difference between revisions of "Eyanosch Week 4"

Revision as of 04:28, 29 September 2015

Modify the gene sequence string so that it highlights or “tags” the special sequences within this gene:

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- Human genes
-about 50% repeated bp's
+#Modify the gene sequence string so that it highlights or “tags” the special sequences within this gene:
-about 5% code for proteins
+#What is the exact mRNA sequence that is transcribed from this gene?
+#What is the amino acid sequence that is translated from this mRNA?
-% are regulatory (differentiation)
-million bp's = human genome size
-Roughly ~ 20,296 genes (protein coding genes)
-humans have about 100,000 different proteins in our cells
-Open reading frame and doing translation = area coded for a certain gene
-'''Bioinformatics'''
-Database analytical tools - available access to lots of data
-*information
-**representation, organization, manipulation, distribution, maintenance
-transcends all science, interdisciplinary
-check out Data life cycle (plan, collect, assure, describe, preserver, discover, integrate, analyze)
-*Key Concepts
-** ID's = identifiers
-** Record = entry in a database
-** searching a database is executing a query
-** Different databases use different file formats
-Pertinent types for this class
--Sequence
--3d structure
--Model organism databases
--etc.
-Major databases to note
-#NCBI: National Center for Biotechnology Information
-#*GenBank
-#*Gene
-#*Pubmed
-#uniprot (formerly SWISS-PROT