Difference between revisions of "Aporras1 Week 4"
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| + | #Met outside of class with [[User:Cazinge|Eddie Azinge]] to discuss any questions we had prior to meeting and throughout the process of completing the Week 4 assignment. | ||
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| + | '''While I worked with the people noted above, this individual journal entry was completed by me and not copied from another source.''' | ||
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==References== | ==References== | ||
Revision as of 04:03, 26 September 2017
User Page: Antonio Porras
Assignment Page: Week 4
Electronic Notebook
- I visited the SGD Database and we chose the CLN1 gene as the model organism.
- First, searched through information on the SGD database and found the following going from the top to the bottom of the page:
- Overview: regulation of cell cycle promoting first growth phase to S phase.
- Found on chromosome XIII; also provides the sequence.
- Cyclin dependent protein kinase.
- Found within the nucleus and the cytoplasm.
- Encodes for a G1 cyclin which regulates the cell cycle.
- Cyclins are essential because they activate CDKs at the correct times within the cell cycle.
- Provides length of protein to be 546 a.a., PI to be 5.62, and molecular weight to be 62038.2
- ANother observation on the website, it provides additional literature regarding the study of CLN1.
- I then searched on the NCBI Gene Database and gathered what I thought to be relevant information going from the top to the bottom of the webpage:
- A protein coding gene also known as YMR199W
- The genomic sequence is NC_001145.3
- Provides various interactions with other genes, however this list is extensive/exhaustive and not essential to understand the function of the gene.
- Provides further links to PubMed articles on CLN1.
- Ontology processes: cell cycle, cell division, G1/S transition of mitotic cell cycle, regulation of serine/threonine kinase activity.
- Name of the protein: NP_013926
- Name of mRNA: NM_001182706.1
Acknowledgements
- Met outside of class with Eddie Azinge to discuss any questions we had prior to meeting and throughout the process of completing the Week 4 assignment.
While I worked with the people noted above, this individual journal entry was completed by me and not copied from another source.
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References
- LMU BioDB 2017. (2017). Week 3. Retrieved September 16, 2017, from https://xmlpipedb.cs.lmu.edu/biodb/fall2017/index.php/Week_3
- Ncbi.nlm.nih.gov. (2017). CLN1 cyclin CLN1 [Saccharomyces cerevisiae S288C] - Gene - NCBI. [online] Available at: https://www.ncbi.nlm.nih.gov/gene/855239 [Accessed 26 Sep. 2017].
- Yeastgenome.org. (2017). CLN1 | SGD. [online] Available at: https://www.yeastgenome.org/locus/S000004812 [Accessed 26 Sep. 2017].
