QLanners Week 4

For this week's assignment, Emma Tyrnauer and I surfed the Saccharomyces Genome Database (SGD) after Thursday's class period. We picked the gene ADA2 as our favorite gene to focus on for the week.

To start this week's assignment, Emma and I decided to both individually do the initial research on the ADA2 gene using the four websites on the assignment page. I started my research by visiting the SGD website on 9/24 . From here I obtained the following information:

• Standard Name: ADA2
• Systematic Name: YDR448W
• Name Description: transcriptional ADAptor
• Gene ID (from SGD): S000002856
• Web address of gene to be used for hyperlink on webpage: https://www.yeastgenome.org/locus/S000002856
• DNA Sequence:

1 ATGTCAAACA AGTTTCACTG TGACGTTTGT TCAGCTGATT GCACGAACAG AGTGAGGGTT
61 TCATGTGCTA TTTGTCCCGA ATACGACTTA TGCGTGCCCT GCTTTTCACA AGGCTCGTAT
121 ACAGGAAAGC ATCGCCCTTA CCATGATTAT AGGATAATAG AGACCAATTC ATACCCCATT
181 CTCTGTCCTG ATTGGGGTGC CGATGAAGAA TTGCAGTTGA TTAAAGGCGC ACAGACTTTA
241 GGGCTCGGTA ATTGGCAGGA TATTGCTGAC CATATAGGCA GCAGAGGCAA AGAAGAAGTT
301 AAGGAACATT ACCTAAAATA TTATCTGGAA AGCAAATACT ATCCAATACC TGATATTACC
361 CAAAATATAC ATGTCCCACA AGATGAATTT TTGGAACAGC GAAGGCATAG AATCGAGTCC
421 TTCCGGGAGA GGCCGCTAGA GCCTCCAAGA AAGCCCATGG CATCGGTTCC TAGCTGCCAT
481 GAAGTACAGG GGTTTATGCC GGGCAGATTA GAATTTGAAA CAGAATTCGA AAATGAAGCT
541 GAAGGTCCCG TAAAGGATAT GGTTTTTGAA CCTGATGACC AGCCCTTAGA CATTGAATTG
601 AAGTTTGCCA TCTTGGACAT TTACAATTCT AGATTGACAA CCAGAGCAGA AAAGAAAAGG
661 CTATTATTTG AAAACCATTT AATGGATTAC AGAAAGTTGC AAGCTATTGA CAAAAAGAGG
721 AGCAAAGAAG CCAAAGAATT GTATAACCGC ATAAAACCTT TTGCTCGTGT TATGACTGCA
781 CAGGATTTTG AGGAATTTAG CAAGGATATA TTAGAAGAAT TGCATTGCAG GGCAAGAATA
841 CAGCAATTAC AAGAATGGAG AAGCAATGGG TTAACCACGT TAGAAGCAGG TCTTAAGTAT
901 GAACGAGATA AGCAAGCTAG AATTAGCAGT TTCGAGAAAT TTGGCGCTTC TACGGCGGCG
961 TCACTCAGTG AGGGCAATAG CCGTTATAGG TCGAATTCTG CACATAGGTC GAACGCAGAA
1021 TACAGCCAAA ACTACAGCGA AAATGGCGGT AGAAAGAAAA ATATGACCAT TAGCGATATA
1081 CAGCATGCAC CTGACTATGC ACTGTTGTCC AACGACGAGC AGCAACTTTG TATTCAACTG
1141 AAAATTTTAC CTAAACCGTA TCTCGTTCTA AAAGAGGTAA TGTTCAGAGA ACTGTTGAAG
1201 ACTGGGGGTA ATCTAAGCAA AAGCGCATGT AGGGAACTAC TTAATATAGA CCCCATAAAA
1261 GCGAATAGAA TATACGATTT TTTCCAGAGC CAGAATTGGA TGTAA

• Protein Sequence:

1 MSNKFHCDVC SADCTNRVRV SCAICPEYDL CVPCFSQGSY TGKHRPYHDY RIIETNSYPI
61 LCPDWGADEE LQLIKGAQTL GLGNWQDIAD HIGSRGKEEV KEHYLKYYLE SKYYPIPDIT
121 QNIHVPQDEF LEQRRHRIES FRERPLEPPR KPMASVPSCH EVQGFMPGRL EFETEFENEA
181 EGPVKDMVFE PDDQPLDIEL KFAILDIYNS RLTTRAEKKR LLFENHLMDY RKLQAIDKKR
241 SKEAKELYNR IKPFARVMTA QDFEEFSKDI LEELHCRARI QQLQEWRSNG LTTLEAGLKY
301 ERDKQARISS FEKFGASTAA SLSEGNSRYR SNSAHRSNAE YSQNYSENGG RKKNMTISDI
361 QHAPDYALLS NDEQQLCIQL KILPKPYLVL KEVMFRELLK TGGNLSKSAC RELLNIDPIK
421 ANRIYDFFQS QNWM*

• Function of your gene:
  • Binding to chromatin
  • Catalysis the reaction of acetyl-CoA with histone to make CoA and acetyl-histone
  • Phosphatidylserine binding
  • transcription coactivator activity to increase the frequency, rate, or duration of transcription

What was different about the information provided about your gene in each of the parent databases?