Aporras1 Week 4

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User Page: Antonio Porras

Assignment Page: Week 4

Electronic Notebook

  1. I visited the SGD Database and we chose the CLN1 gene as the model organism.
  2. First, searched through information on the SGD database:
    • Overview: regulation of cell cycle promoting first growth phase to S phase.
    • Found on chromosome XIII; also provides the sequence.
    • Cyclin dependent protein kinase.
    • Found within the nucleus and the cytoplasm.
    • Encodes for a G1 cyclin which regulates the cell cycle.
    • Cyclins are essential because they activate CDKs at the correct times within the cell cycle.
    • Provides length of protein to be 546 a.a., PI to be 5.62, and molecular weight to be 62038.2
    • ANother observation on the website, it provides additional literature regarding the study of CLN1.