Jcowan4 Journal Week 11 - Revision history

Jcowan4: /* Annotated Bibliography */ answered

2019-11-19T07:58:02Z

‎Annotated Bibliography: answered

Jcowan4: /* Conclusion */ conclusion about this week 11/18/2019

2019-11-19T06:07:39Z

‎Conclusion: conclusion about this week 11/18/2019

Jcowan4: /* Annotated Bibliography */ answered ref 2

2019-11-19T06:04:46Z

‎Annotated Bibliography: answered ref 2

Jcowan4: /* Annotated Bibliography */ header

2019-11-19T05:44:08Z

‎Annotated Bibliography: header

Jcowan4: /* Annotated Bibliography */ Finished reference 1

2019-11-19T05:39:46Z

‎Annotated Bibliography: Finished reference 1

Jcowan4: /* Annotated Bibliography */ answered

2019-11-19T04:34:27Z

‎Annotated Bibliography: answered

Jcowan4: /* Data/Files */ added presentation

2019-11-14T07:58:51Z

‎Data/Files: added presentation

Jcowan4: /* Biological Terms */ added definition

2019-11-14T06:14:06Z

‎Biological Terms: added definition

Jcowan4: /* References */ added references

2019-11-14T05:55:02Z

‎References: added references

Jcowan4: /* Briefly state the result shown in each of the figures and tables, not just the ones you are presenting. */ answering

2019-11-14T05:50:19Z

‎Briefly state the result shown in each of the figures and tables, not just the ones you are presenting.: answering

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 # Review Article
 # NA
 ==Data/Files==

← Older revision		Revision as of 06:07, 19 November 2019
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	==Conclusion==		==Conclusion==
		+
		+	This week, I learned how to reference sources and to look up information to confirm its viability. I also learned how to properly format a presentation.

	==Acknowledgements==		==Acknowledgements==

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 *#* Web of Science
 *#** Which advanced search functions were most useful to narrow down the search?  How many results did you get? The most useful functions included: Times cited, Usage count, date after (year). Results went from 60 to 11
 '''REFERENCE 1'''
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 # Article is open to the public
 # Availibility: Online
-# Publisher: POS Biology
+# Publisher: PLOS Biology
 # Earliest Publish Date: 2003
 # Peer-reviewed: Yes
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 # Primary Research article
 # https://ndownloader.figshare.com/files/471538
 ==Data/Files==

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 # Primary research article
 # Data are not available (dead hyperlink)
 # Hess, D. C., Lu, W., Rabinowitz, J. D., & Botstein, D. (2006). Ammonium toxicity and potassium limitation in yeast. PLoS biology, 4(11), e351. '''DOI: 10.1371/journal.pbio.0040351'''

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 # Primary research article
 # Data are not available (dead hyperlink)
 ==Data/Files==

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 *# Use a keyword search for the first three databases/tools and answer the following:
 *#* PubMed
-*#** What original keyword(s) did you use?  How many results did you get?
+*#** What original keyword(s) did you use?  How many results did you get? Yeast (283103), potassium (259156), potassium and yeast (3055)
-*#** Which terms in which combinations were most useful to narrow down the search?  How many results did you get after narrowing the search?
+*#** Which terms in which combinations were most useful to narrow down the search?  How many results did you get after narrowing the search? Potassium starvation and yeast (66)
 *#* Google Scholar
-*#** What original keyword(s) did you use?  How many results did you get?
+*#** What original keyword(s) did you use?  How many results did you get? Yeast (3090000), potassium (4370000), potassium and yeast (1290000)
-*#** Which terms in which combinations were most useful to narrow down the search?  How many results did you get after narrowing the search?
+*#** Which terms in which combinations were most useful to narrow down the search?  How many results did you get after narrowing the search? potassium starvation and yeast (41600)
 *#* Web of Science
-*#** What original keyword(s) did you use?  How many results did you get?
+*#** What original keyword(s) did you use?  How many results did you get? Yeast (272999), potassium (271094), potassium and yeast (2162)
-*#** Which terms in which combinations were most useful to narrow down the search?  How many results did you get after narrowing the search?
+*#** Which terms in which combinations were most useful to narrow down the search?  How many results did you get after narrowing the search? Potassium starvation and yeast (60)
 *# Use the advanced search functions for each of these three databases/tools and answer the following:
 *#* PubMed
-*#** Which advanced search functions were most useful to narrow down the search?  How many results did you get?
+*#** Which advanced search functions were most useful to narrow down the search?  How many results did you get? The most useful included: Text availability, most recent, filtering out the older articles. It narrowed down my search to under 100 articles.
 *#* Google Scholar
-*#** Which advanced search functions were most useful to narrow down the search?  How many results did you get?
+*#** Which advanced search functions were most useful to narrow down the search?  How many results did you get? The most useful functions include: time intervals of when the articles were released/updated, date. The result changed from 21600 to 2100.
 *#* Web of Science
-*#** Which advanced search functions were most useful to narrow down the search?  How many results did you get?
+*#** Which advanced search functions were most useful to narrow down the search?  How many results did you get? The most useful functions included: Times cited, Usage count, date after (year). Results went from 60 to 11
 *#* Perform a prospective search on your article in the Web of Science and answer the following:
 *#** How many articles does this article cite?
 *#** How many articles cite this article?
 ==Data/Files==

← Older revision		Revision as of 07:58, 14 November 2019
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	==Data/Files==		==Data/Files==
		+
		+	[[Media:Jonar_Cowan_Team_Skinny_Genes.pdf \| Skinny Genes Presentation]]

	==Conclusion==		==Conclusion==

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 ==Biological Terms==
-Intracellular
+Intracellular: Occurring or being (situated) inside a cell or cells. (Biology Online, 2019)
-Transcriptomic
+Transcriptomic: The study of all RNA molecules in a cell. RNA is copied from pieces of DNA and contains information to make proteins and perform other important functions in the cell. Transcriptomics is used to learn more about how genes are turned on in different types of cells and how this may help cause certain diseases, such as cancer.
-Extracellular
+Extracellular: Occurring or being (situated) outside the cell or cells. (Biology Online, 2019)
-Methionine
+Methionine: (Science: biochemistry) Contains the SCH3 group that can act as a methyl donor (see s adenosyl methionine). Common in proteins but at low frequency. The met x linkage is subject to specific cleavage by cyanogen bromide. (Biology Online, 2019)
-Biosynthesis
+Biosynthesis: The production of a complex chemical compound from simpler precursors in a living organism, usually involving enzymes (to catalyze the reaction) and energy source (such as ATP). (Biology Online, 2019)
-B-galactosidase
+B-galactosidase: A protein complex that possesses beta-galactosidase activity, i.e. catalyzes the hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides. In E. coli, the complex is a homotetramer; dimeric and hexameric beta-galactosidase complexes have been observed in other species.
-Homocysteine
+Homocysteine: The chemical reactions and pathways resulting in the formation of homocysteine, 2-amino-4-sulfanylbutanoic acid.
-Oxidative
+Oxidative: Capable of oxidizing other substances. Of, pertaining to, or produced by oxidation. (Biology Online, 2019)
-Glutathione
+Glutathione: (Science: biochemistry) The tripeptide _ glutamylcysteinylglycine. It contains an unusual peptide Linkage between the _ carboxyl group of the glutamate side chain and the amine group of cysteine. (Biology Online, 2019)
-Substrate
+Substrate: A substratum or an underlying stratum. (Biology Online, 2019)
-Transduction
+Transduction: there are a group of viruses called bacteriophages. These bacteriophages inject their viral dna into the host cell of bacteria. The viral dna then becomes incorporated into the chromosome of the bacterium. Thus the viral dna forms part of the bacterial chromosome and will be copied to all daughter cells. Though this viral dna will become active again at low frequency's. (Biology Online, 2019)
 ==Outline==

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 ==References==
 {{jcowan4}}
 (*Participation: Table 2, Introduction (Background Information), Question 1, Question 3)

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 ===Briefly state the result shown in each of the figures and tables, not just the ones you are presenting.===
 '''Table 1''' shows the transcriptional changes between 10, 20, 40, 60, and 120 minutes. It measures the amount of genes that are induced and repressed at each timepoint.
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 '''Figure 4''' shows the effects of methylglyoxal production and treholse production from potassium starvation. '''A''' shows how the production of each is made. '''B''' shows the changes in expression '''X''' = Timepoint '''Y''' = Changes in expression (-fold). '''C''' shows the levels of methyglyoxal when affected by potassium starvation. '''X''' = Timepoint '''Y''' = Methyglyoxal Levels.
-'''Figure 5''' shows the a correlation between the expression of CIT2 and DLD3 genes and potassium starvation. '''A''' shows the changes in expression for genes and an image of the changes in CIT2, DLD3 and ACT1. '''B''' shows the changes in mitochondrial change before and after the procedure and images of WT and fzo1. '''C'''
+'''Figure 5''' shows the a correlation between the expression of CIT2 and DLD3 genes and potassium starvation. '''A''' shows the changes in expression for genes and an image of the changes in CIT2, DLD3 and ACT1. '''B''' shows the changes in mitochondrial change before and after the procedure and images of WT and fzo1. '''C''' & '''D''' shows the graph depicting the relative concentration of intracellular ammonium after treatment.
-'''Figure 6'''
+'''Figure 6''' shows expression of genes controlling cyclins express various responses to potassium starvation. '''A''' shows a graph demonstrating the change in expression levels of retrograde after potassium starvation. '''X''' = Timepoint '''Y''' = log2 change in expression levels. '''B''' are images depicting relative abundance of cyclin mRNA & '''C''' are images depicting relative abundance of cyclin protein
-'''Figure 7'''
+'''Figure 7''' shows that potassium starvation decreases septin ring formation. '''A''' shows a graph that represents the change in expression levels of septin ring fomration genes after potassium starvation. '''B''' are images depicting the localization of Cdc11-GFP during treatment. '''C''' are images depicting relative abundance of Cdc11 protein. '''D''' are images depicting the localization of Cdc11 protein
 ===How does this work compare with previous studies?===