Knguye66 Eyoung20 Week 12/13

Combined Individual Journals for Kaitlyn Nguyen and Emma Young (Data Analysts).

Methods and Results: Progress

Progress 11/21/19

Our group decided to have the ANOVA, sanity check, and STEM set-up done before class on Thursday, 11/21/19. After finishing the steps on Week 8 for Statistical Analysis Part I: ANOVA on Microsoft Excel for the new MicroArray Data found on the Data_Analysis page, a quick sanity check was performed for the p-value dataset.

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Sanity Check Questions:

-Unadjusted p-value-

1. How many genes have p<0.05? and what is the percentage (out of 6189)?
   • 2528, 40.8%
2. How many genes have p<0.01? and what is the percentage (out of 6189)?
   • 1652, 26.7%
3. How any genes have p<0.001? and what is the percentage (out of 6189)?
   • 919, 14.8%
4. How many genes have p<0.0001? and what is the percentage (out of 6189)?
   • 496, 8.0%

-Bonferroni & Benjamini and Hochberg p-value-

1. How any genes are p<0.05 for the Bonferroni-corrected p-value? and what is the percentage (out of 6189)?
   • 248, 4.0%
2. How any genes are p <0.05 for the Benjamini and Hochberg-corrected p-value? and what is the percentage (out of 6189)?
   • 1822, 29.4%

-NSR1-

1. What is its unadjusted, Bonferroni-corrected, and B-H-corrected p-values?
   • Unadjusted: 2.86939E-10
   • Bonferroni: 1.77586E-06
   • B-H: 8.87932E-07
   • Average Log fold:
     • t15: 3.279225
     • t30: 3.621
     • t60: 3.526525
     • t90: -2.04985
     • t120: -0.60622

-Favorite Gene (YDR090C)-

1. • Unadjusted: 0.519632074
   • Bonferroni: 3216.002905
   • B-H: 0.641276751
   • Average Log fold:
     • t15: -0.067
     • t30: 0.51286
     • t60: 0.5417
     • t90: -0.27156
     • t120: -0.06704

Acknowledgements

This section is in acknowledgement to partner Kaitlyn Nguyen (User:knguye66), Michael Armas (User:Marmas), as well as, Iliana Crespin (User:Icrespin), and Emma Young (User:eyoung20). We would also like to acknowledge Dr. Dahlquist (User:KDahlquist) for introducing and teaching the topic and direction of this assignment.

"Except for what is noted above, this individual journal entry was completed by me and not copied from another source."