Mavila9 Week 12 Journal

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10 Words I Didn't Understand Before

1. Acute promyelocytic leukemia - An aggressive type of acute myeloid leukemia in which there are too many immature blood-forming cells in the blood and bone marrow. It is usually marked by an exchange of parts of chromosomes 15 and 17. Also called APL and promyelocytic leukemia (NCI Dictionary of Cancer Terms).
2. Aquaglyceroporin - integral membrane proteins that are permeable to glycerol as well as water (Grosell, 2003).
3. Chelation - the combination of a metal ion with a chemical compound, forming a ring (biology-online.org dictionary).
4. Glutathionylation - the specific post-translational modification of protein cysteine residues by the addition of the tripeptide glutathione, the most abundant and important low-molecular-mass thiol within most cell types (Dalle-Donne, 2009).
5. Auxotrophic - any strain of microorganism (alga, bacterium, or fungus) that differs from the wild‐type by requiring a supply of one or more growth factors (Oxford Dictionary of Biochemistry and Molecular Biology).
6. Orthologue - a gene, protein, or biopolymeric sequence that is evolutionarily related to another by descent from a common ancestor, having diverged as a result of a speciation event (Oxford Dictionary of Biochemistry and Molecular Biology).
7. Dichotomous - a term that describes dividing into two parts or classifications (biology-online.org dictionary).
8. Antioxidant - any substance that inhibits oxidation, usually because it is preferentially oxidized itself (Lackie, 2007).
9. Glutathione - most abundant non-protein thiol, synthesized in the cytosol, that protects against oxidative stress, and regulates cell proliferation, immune response, apoptosis, and fibrogenesis (Lu, 2012)
10. Ubiquitination - formation of a highly efficient and selective isopeptide bond between a substrate lysine residue and the C-terminus of ubiquitin catalyzed by ubiquitin-protein ligase, or E3 (Pickart, 2001).

=Conclusion

References

(2006). auxotroph. In Cammack, R., Atwood, T., Campbell, P., Parish, H., Smith, A., Vella, F., & Stirling, J. (Eds.), Oxford Dictionary of Biochemistry and Molecular Biology. : Oxford University Press. Retrieved 12 Nov. 2019, from [1] Dalle-Donne, I., Rossi, R., Colombo, G., Giustarini, D., & Milzani, A. (2009). Protein S-glutathionylation: a regulatory device from bacteria to humans. Trends in biochemical sciences, 34(2), 85-96. doi: [2] Grosell, M., & Bury, N. R. (2003). Biochimica et Biophysica Acta (BBA)/Biomembranes: Preface. Biochimica et Biophysica Acta-Biomembranes, 1618(2). doi: [3] Lackie, J. M., & Lackie, J. M. (Eds.). (2007). The dictionary of cell and molecular biology. Retrieved from [4] Lu, S. C. (2013). Glutathione synthesis. Biochimica et Biophysica Acta (BBA)-General Subjects, 1830(5), 3143-3153. doi: [5] Pickart, C. M. (2001). Mechanisms underlying ubiquitination. Annual review of biochemistry, 70(1), 503-533. doi: [6]