Cdomin12 Week 11
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Contents
- 1 1. What is the main result presented in this paper?
- 2 2. What is the importance or significance of this work?
- 3 3. What were the limitations in previous studies that led them to perform this work?
- 4 4. How did they treat the yeast cells (what experiment were they doing?)
- 5 5. What strain(s) of yeast did they use? Were the strain(s) haploid or diploid?
- 6 6. What media did they grow them in? What temperature? What type of incubator? For how long?
- 7 7. What controls did they use?
- 8 8. How many replicates did they perform per treatment or timepoint?
- 9 9. What method did they use to prepare the RNA, label it and hybridize it to the microarray?
- 10 10. What mathematical/statistical method did they use to analyze the data?
- 11 11. Are the data publicly available for download? From which web site?
- 12 12. Briefly state the result shown in each of the figures and tables, not just the ones you are presenting.
- 13 13. What do the X and Y axes represent?
- 14 14. How were the measurements made?
- 15 15. What trends are shown by the plots and what conclusions can you draw from the data?
- 16 16. How does this work compare with previous studies?
- 17 17. What are the important implications of this work?
- 18 18. What future directions should the authors take?
- 19 19. Give a critical evaluation of how well you think the authors supported their conclusions with the data they showed. Are there any major flaws to the paper?
