Hivanson Week 10

Methods/Results

Why did you select this profile? In other words, why was it interesting to you? I selected profile 22 because the overall trend of a spike only at 90 minutes is different from the rest of the profiles' trends.

How many genes belong to this profile? 46 genes belong to profile 22.

How many genes were expected to belong to this profile? 23.6 genes were expected to be in profile 22.

What is the p value for the enrichment of genes in this profile? 2.3E-5

How many GO terms are associated with this profile at p < 0.05? 25

How many GO terms are associated with this profile with a corrected p value < 0.05? 7

GO ID Definitions

GO ID	Definition
GO:0034599	cellular response to oxidative stress
GO:0005737	cytoplasm
GO:0006897	endocytosis
GO:0030479	actin cortical patch
GO:0005856	cytoskeleton
GO:0000324	fungal-type vacuole

Why does the cell react to cold shock by changing the expression of genes associated with these GO terms?

The genes that are associated with these GO terms include stress responses, like cellular response to oxidative stress, and its related terms that I excluded from the above table due to similarity. This makes sense as cold shock is considered a stressor. Additionally, various cellular structure components are associated with these GO terms, such as cytoplasm, cytoskeleton, and fungal-type vacuole which are

Also, what does this have to do with the transcription factor being deleted (for the groups working with deletion strain data)

Data & Files

Excel file with microarray data for dCIN5

Tab text file with dCIN5 stem data

stem dCIN5 significant profiles genelist folder

stem dCIN5 significant profiles GOlist folder

References

• Help:Table. (2024). In Wikipedia. Retrieved January 17, 2023, from https://en.wikipedia.org/w/index.php?title=Help:Table&oldid=1213890372

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